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CFH ,CFH ,P08603
  • Uniprot Accession= P08603
  • Ensembl Transcript= ENST00000367429.8
  • Uniprot Name= CFH
  • Name= Complement factor H
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 20
  • Number of Interaction partner in biogrid: 16
  • Number of Interaction partner in hippie: 41
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADM ADM P35318 Pro-adrenomedullin chr11 Not Cancer Driver No 1 hippie 20 113 13 13 0
AGPAT1 AGPAT1 Q99943 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha chr6 Not Cancer Driver No 1 hippie, biogrid 36 38 5 5 0
ALB ALB P02768 Albumin chr4 Compendium Yes 2 intact, hippie 162 6 0 0 3
APOE APOE P02649 Apolipoprotein E chr19 Not Cancer Driver No 1 intact, hippie 25 124 6 6 12
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 Census, Compendium Yes 1 hippie 457 1542 225 225 46
C3 C3 P01024 Complement C3 chr19 Not Cancer Driver No 11 intact, hippie 337 287 50 50 12
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 Not Cancer Driver No 1 hippie, biogrid 69 14 5 5 0
CFB CFB P00751 Complement factor B chr6 Not Cancer Driver No 1 intact, hippie 75 112 20 20 7
CFH CFH P08603 Complement factor H chr1 Not Cancer Driver No 3 intact, hippie 355 89 28 28 42
CFHR1 CFHR1 Q03591 Complement factor H-related protein 1 chr1 Not Cancer Driver No 2 intact 68 42 11 11 0
CFHR3 CFHR3 Q02985 Complement factor H-related protein 3 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 87 12 5 5 0
CFHR4 CFHR4 Q92496 Complement factor H-related protein 4 chr1 Not Cancer Driver No 1 intact, hippie 192 11 4 4 0
CFI_ENST00000394634 CFI P05156 Complement factor I chr4 Not Cancer Driver No 7 intact, hippie 97 4 0 0 13
CRP CRP P02741 C-reactive protein chr1 Not Cancer Driver No 13 intact, hippie 59 0 0 0 0
DMP1 DMP1 Q13316 Dentin matrix acidic phosphoprotein 1 chr4 Not Cancer Driver No 1 hippie 106 495 104 104 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 Not Cancer Driver No 1 intact 147 211 38 38 0
FMOD FMOD Q06828 Fibromodulin chr1 Not Cancer Driver No 1 intact 84 48 10 10 0
GNG8 GNG8 Q9UK08 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 chr19 Not Cancer Driver No 1 hippie, biogrid 2 16 1 1 0
GOT1 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 Not Cancer Driver No 1 hippie, biogrid 56 35 5 5 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 Not Cancer Driver No 1 hippie 191 133 12 12 0
KLHL18 KLHL18 O94889 Kelch-like protein 18 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 82 31 10 10 0
KLK10_ENST00000358789 KLK10 O43240 Kallikrein-10 chr19 Not Cancer Driver No 1 hippie, biogrid 35 30 8 8 0
MATN2 MATN2 O00339 Matrilin-2 chr8 Not Cancer Driver No 1 hippie, biogrid 151 167 26 26 0
MBNL1_ENST00000463374 MBNL1 Q9NR56 Muscleblind-like protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 56 153 20 20 0
MMUT MMUT P22033 Methylmalonyl-CoA mutase, mitochondrial chr6 Not Cancer Driver No 1 intact, hippie 107 99 11 11 125
PHF11 PHF11 Q9UIL8 PHD finger protein 11 chr13 Not Cancer Driver No 1 hippie, biogrid 34 82 10 10 0
PTX3 PTX3 P26022 Pentraxin-related protein PTX3 chr3 Not Cancer Driver No 3 intact, hippie 39 74 2 2 0
RHBDD1 RHBDD1 Q8TEB9 Rhomboid-related protein 4 chr2 Not Cancer Driver No 1 hippie, biogrid 38 69 9 9 0
SARAF SARAF Q96BY9 Store-operated calcium entry-associated regulatory factor chr8 Not Cancer Driver No 1 hippie, biogrid 32 73 8 8 0
SELL SELL P14151 L-selectin chr1 Not Cancer Driver No 1 hippie 68 20 3 3 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 intact, hippie 97 111 19 19 5
SSUH2 SSUH2 Q9Y2M2 Protein SSUH2 homolog chr3 Not Cancer Driver No 1 hippie, biogrid 58 76 7 7 0
ST6GALNAC6_ENST00000373146 ST6GALNAC6 Q969X2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 chr9 Not Cancer Driver No 1 hippie, biogrid 44 86 13 13 0
STX17_ENST00000534052 STX17 P56962 Syntaxin-17 chr9 Not Cancer Driver No 1 hippie, biogrid 27 81 4 4 0
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 Not Cancer Driver No 1 hippie 77 275 44 44 4
TFAP2C TFAP2C Q92754 Transcription factor AP-2 gamma chr20 Not Cancer Driver No 1 intact, hippie 76 282 41 41 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 Not Cancer Driver No 1 hippie 188 320 58 58 0
UBE2U_ENST00000611228 UBE2U Q5VVX9 Ubiquitin-conjugating enzyme E2 U chr1 Not Cancer Driver No 1 hippie, biogrid 38 66 1 1 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 Not Cancer Driver No 1 hippie 64 102 16 16 14
VPS16 VPS16 Q9H269 Vacuolar protein sorting-associated protein 16 homolog chr20 Not Cancer Driver No 1 intact, hippie 104 34 5 5 1
YTHDC1_ENST00000344157 YTHDC1 Q96MU7 YTH domain-containing protein 1 chr4 Not Cancer Driver No 1 intact, hippie 137 597 117 117 0
ZBTB16_ENST00000392996 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 Census, Compendium Yes 1 hippie 131 268 50 50 1