Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACKR2 | ACKR2 | O00590 | Atypical chemokine receptor 2 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 25 | 6 | 6 | 0 |
AGR2 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 20 | 2 | 2 | 0 |
AHNAK | AHNAK | Q09666 | Neuroblast differentiation-associated protein AHNAK | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 805 | 5777 | 794 | 794 | 0 |
AHNAK2 | AHNAK2 | Q8IVF2 | Protein AHNAK2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 1074 | 5470 | 1018 | 1018 | 0 |
AKAP2_ENST00000259318 | AKAP2 | Q9Y2D5 | A-kinase anchor protein 2 | chr9 | Not Cancer Driver | No | 1 | hippie | 137 | 852 | 134 | 134 | 0 |
ANXA6 | ANXA6 | P08133 | Annexin A6 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 107 | 15 | 15 | 0 |
ARHGEF7 | ARHGEF7 | Q14155 | Rho guanine nucleotide exchange factor 7 | chr13 | Not Cancer Driver | No | 1 | hippie | 106 | 301 | 39 | 39 | 0 |
ARVCF | ARVCF | O00192 | Armadillo repeat protein deleted in velo-cardio-facial syndrome | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 115 | 618 | 68 | 68 | 0 |
ASGR1 | ASGR1 | P07306 | Asialoglycoprotein receptor 1 | chr17 | Not Cancer Driver | No | 2 | intact, hippie | 23 | 95 | 5 | 5 | 0 |
ASGR2 | ASGR2 | P07307 | Asialoglycoprotein receptor 2 | chr17 | Not Cancer Driver | No | 2 | intact, hippie | 49 | 71 | 8 | 8 | 0 |
ATP2A1 | ATP2A1 | O14983 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 80 | 11 | 11 | 1 |
ATP5F1A_ENST00000282050 | ATP5F1A | P25705 | ATP synthase subunit alpha, mitochondrial | chr18 | Not Cancer Driver | No | 1 | hippie | 66 | 23 | 5 | 5 | 2 |
ATP5F1B | ATP5F1B | P06576 | ATP synthase subunit beta, mitochondrial | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 60 | 85 | 8 | 8 | 0 |
ATP5F1C | ATP5F1C | P36542 | ATP synthase subunit gamma, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie | 39 | 11 | 0 | 0 | 0 |
ATP5F1D_ENST00000591660 | ATP5F1D | P30049 | ATP synthase subunit delta, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie | 7 | 5 | 1 | 1 | 2 |
ATP5IF1 | ATP5IF1 | Q9UII2 | ATPase inhibitor, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 8 | 85 | 7 | 7 | 0 |
ATP5ME | ATP5ME | P56385 | ATP synthase subunit e, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie | 6 | 18 | 2 | 2 | 0 |
ATP5PB | ATP5PB | P24539 | ATP synthase F(0) complex subunit B1, mitochondrial | chr1 | Not Cancer Driver | No | 2 | intact, hippie | 37 | 2 | 0 | 0 | 0 |
ATP5PF_ENST00000400090 | ATP5PF | P18859 | ATP synthase-coupling factor 6, mitochondrial | chr21 | Not Cancer Driver | No | 1 | hippie | 14 | 15 | 1 | 1 | 0 |
ATP6AP2 | ATP6AP2 | O75787 | Renin receptor | chrX | Not Cancer Driver | No | 1 | intact, hippie | 56 | 0 | 0 | 0 | 2 |
ATP6V0A2 | ATP6V0A2 | Q9Y487 | V-type proton ATPase 116 kDa subunit a 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 88 | 36 | 6 | 6 | 0 |
ATP6V0C | ATP6V0C | P27449 | V-type proton ATPase 16 kDa proteolipid subunit c | chr16 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 19 | 1 | 0 | 0 | 0 |
ATP6V0D2 | ATP6V0D2 | Q8N8Y2 | V-type proton ATPase subunit d 2 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 0 | 0 | 0 | 0 |
BCAP31_ENST00000345046 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 104 | 14 | 14 | 0 |
BIRC2 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 83 | 9 | 9 | 0 |
C1orf21 | C1orf21 | Q9H246 | Uncharacterized protein C1orf21 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 121 | 16 | 16 | 0 |
C3AR1 | C3AR1 | Q16581 | C3a anaphylatoxin chemotactic receptor | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 88 | 72 | 16 | 16 | 0 |
C5AR1 | C5AR1 | P21730 | C5a anaphylatoxin chemotactic receptor 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 0 | 0 | 0 | 0 |
CA9 | CA9 | Q16790 | Carbonic anhydrase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 72 | 274 | 50 | 50 | 0 |
CACNA2D1_ENST00000356253 | CACNA2D1 | P54289 | Voltage-dependent calcium channel subunit alpha-2/delta-1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 277 | 99 | 25 | 25 | 0 |
CADM4 | CADM4 | Q8NFZ8 | Cell adhesion molecule 4 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 94 | 9 | 9 | 0 |
CCNY | CCNY | Q8ND76 | Cyclin-Y | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 94 | 6 | 6 | 0 |
CCNYL1 | CCNYL1 | Q8N7R7 | Cyclin-Y-like protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 100 | 8 | 8 | 0 |
CD2AP | CD2AP | Q9Y5K6 | CD2-associated protein | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 456 | 60 | 60 | 0 |
CD63_ENST00000552692 | CD63 | P08962 | CD63 antigen | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 0 | 0 | 0 | 0 |
CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
CDCA3 | CDCA3 | Q99618 | Cell division cycle-associated protein 3 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 268 | 26 | 26 | 0 |
CEP41 | CEP41 | Q9BYV8 | Centrosomal protein of 41 kDa | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 253 | 36 | 36 | 0 |
CHMP3 | CHMP3 | Q9Y3E7 | Charged multivesicular body protein 3 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 137 | 13 | 13 | 0 |
CMKLR1 | CMKLR1 | Q99788 | Chemerin-like receptor 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 107 | 24 | 13 | 13 | 0 |
CNTN1 | CNTN1 | Q12860 | Contactin-1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 265 | 220 | 50 | 50 | 0 |
COIL | COIL | P38432 | Coilin | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 385 | 42 | 42 | 0 |
CPNE2_ENST00000535318 | CPNE2 | Q96FN4 | Copine-2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 32 | 4 | 4 | 0 |
CSNK1G2 | CSNK1G2 | P78368 | Casein kinase I isoform gamma-2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 111 | 13 | 13 | 0 |
CSNK1G3_ENST00000361991 | CSNK1G3 | Q9Y6M4 | Casein kinase I isoform gamma-3 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 151 | 22 | 22 | 0 |
DIAPH1 | DIAPH1 | O60610 | Protein diaphanous homolog 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 118 | 692 | 57 | 57 | 1 |
DLG1_ENST00000419354 | DLG1 | Q12959 | Disks large homolog 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 120 | 460 | 67 | 67 | 0 |
DPP4 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 151 | 8 | 1 | 1 | 0 |
DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 127 | 124 | 45 | 45 | 0 |
EEPD1 | EEPD1 | Q7L9B9 | Endonuclease/exonuclease/phosphatase family domain-containing protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 249 | 32 | 32 | 0 |
EFNA5 | EFNA5 | P52803 | Ephrin-A5 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 25 | 6 | 6 | 0 |
EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
EIF3A | EIF3A | Q14152 | Eukaryotic translation initiation factor 3 subunit A | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 181 | 835 | 130 | 130 | 0 |
ELOVL1_ENST00000372458 | ELOVL1 | Q9BW60 | Elongation of very long chain fatty acids protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 32 | 0 | 0 | 0 | 1 |
ELOVL2 | ELOVL2 | Q9NXB9 | Elongation of very long chain fatty acids protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 57 | 8 | 2 | 2 | 0 |
ELOVL3 | ELOVL3 | Q9HB03 | Elongation of very long chain fatty acids protein 3 | chr10 | Not Cancer Driver | No | 1 | hippie | 42 | 1 | 1 | 1 | 0 |
ELOVL4 | ELOVL4 | Q9GZR5 | Elongation of very long chain fatty acids protein 4 | chr6 | Not Cancer Driver | No | 1 | hippie | 68 | 23 | 6 | 6 | 1 |
ELOVL5_ENST00000304434 | ELOVL5 | Q9NYP7 | Elongation of very long chain fatty acids protein 5 | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 34 | 25 | 4 | 4 | 2 |
ELOVL6 | ELOVL6 | Q9H5J4 | Elongation of very long chain fatty acids protein 6 | chr4 | Not Cancer Driver | No | 1 | hippie | 40 | 0 | 0 | 0 | 0 |
ELOVL7_ENST00000425382 | ELOVL7 | A1L3X0 | Elongation of very long chain fatty acids protein 7 | chr5 | Not Cancer Driver | No | 1 | hippie | 41 | 10 | 2 | 2 | 0 |
ENAH | ENAH | Q8N8S7 | Protein enabled homolog | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 514 | 61 | 61 | 0 |
EPB41L2_ENST00000368128 | EPB41L2 | O43491 | Band 4.1-like protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 708 | 113 | 113 | 0 |
EPB41L3 | EPB41L3 | Q9Y2J2 | Band 4.1-like protein 3 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 298 | 695 | 207 | 207 | 0 |
EPPK1 | EPPK1 | P58107 | Epiplakin | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 417 | 1336 | 67 | 67 | 0 |
ERGIC1 | ERGIC1 | Q969X5 | Endoplasmic reticulum-Golgi intermediate compartment protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 26 | 2 | 2 | 0 |
ERICH5 | ERICH5 | Q6P6B1 | Glutamate-rich protein 5 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 374 | 61 | 61 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 2 | intact, hippie | 121 | 195 | 27 | 27 | 2 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
FLOT1 | FLOT1 | O75955 | Flotillin-1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 122 | 15 | 15 | 0 |
FUBP1 | FUBP1 | Q96AE4 | Far upstream element-binding protein 1 | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 88 | 595 | 85 | 85 | 0 |
FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 92 | 70 | 13 | 13 | 0 |
FZD7 | FZD7 | O75084 | Frizzled-7 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 22 | 2 | 2 | 0 |
GABBR2 | GABBR2 | O75899 | Gamma-aminobutyric acid type B receptor subunit 2 | chr9 | Not Cancer Driver | No | 1 | hippie | 169 | 220 | 29 | 29 | 4 |
GAP43_ENST00000305124 | GAP43 | P17677 | Neuromodulin | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 79 | 238 | 79 | 79 | 0 |
GAS1 | GAS1 | P54826 | Growth arrest-specific protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 82 | 4 | 4 | 0 |
GJD3 | GJD3 | Q8N144 | Gap junction delta-3 protein | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 79 | 0 | 0 | 0 |
GNAO1_ENST00000638705 | GNAO1 | P09471 | Guanine nucleotide-binding protein G(o) subunit alpha | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 10 | 0 | 0 | 15 |
GNAQ | GNAQ | P50148 | Guanine nucleotide-binding protein G(q) subunit alpha | chr9 | Census, Compendium | Yes | 1 | hippie, biogrid | 57 | 14 | 1 | 1 | 1 |
GNAS_ENST00000371075 | GNAS | O95467 | Neuroendocrine secretory protein 55 | chr20 | Census, Compendium | Yes | 1 | hippie, biogrid | 71 | 221 | 65 | 65 | 0 |
GNAZ | GNAZ | P19086 | Guanine nucleotide-binding protein G(z) subunit alpha | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 30 | 13 | 13 | 0 |
GPR17 | GPR17 | Q13304 | Uracil nucleotide/cysteinyl leukotriene receptor | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 16 | 4 | 4 | 0 |
GPR173 | GPR173 | Q9NS66 | Probable G-protein coupled receptor 173 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 12 | 0 | 0 | 0 |
GPR35_ENST00000403859 | GPR35 | Q9HC97 | G-protein coupled receptor 35 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 0 | 0 | 0 | 0 |
GPRIN1 | GPRIN1 | Q7Z2K8 | G protein-regulated inducer of neurite outgrowth 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 116 | 999 | 115 | 115 | 0 |
HNRNPH1 | HNRNPH1 | P31943 | Heterogeneous nuclear ribonucleoprotein H | chr5 | Not Cancer Driver | No | 1 | hippie | 51 | 169 | 29 | 29 | 0 |
HRAS | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | hippie, biogrid | 107 | 16 | 4 | 4 | 18 |
HSD17B11 | HSD17B11 | Q8NBQ5 | Estradiol 17-beta-dehydrogenase 11 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 3 | 0 | 0 | 0 |
HSD17B12 | HSD17B12 | Q53GQ0 | Very-long-chain 3-oxoacyl-CoA reductase | chr11 | Not Cancer Driver | No | 1 | hippie | 32 | 9 | 0 | 0 | 0 |
HSD3B7 | HSD3B7 | Q9H2F3 | 3 beta-hydroxysteroid dehydrogenase type 7 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 27 | 5 | 5 | 2 |
HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | Census, Compendium | Yes | 1 | intact, hippie | 106 | 257 | 37 | 37 | 0 |
HTR1B | HTR1B | P28222 | 5-hydroxytryptamine receptor 1B | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 91 | 33 | 15 | 15 | 0 |
HTR2C | HTR2C | P28335 | 5-hydroxytryptamine receptor 2C | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 140 | 40 | 11 | 11 | 0 |
IER3IP1 | IER3IP1 | Q9Y5U9 | Immediate early response 3-interacting protein 1 | chr18 | Not Cancer Driver | No | 1 | intact, hippie | 3 | 0 | 0 | 0 | 2 |
INA | INA | Q16352 | Alpha-internexin | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 256 | 43 | 43 | 0 |
INPP5A | INPP5A | Q14642 | Inositol polyphosphate-5-phosphatase A | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 7 | 4 | 4 | 0 |
IPPK | IPPK | Q9H8X2 | Inositol-pentakisphosphate 2-kinase | chr9 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 55 | 43 | 3 | 3 | 0 |
KDSR | KDSR | Q06136 | 3-ketodihydrosphingosine reductase | chr18 | Census | Yes | 1 | hippie, biogrid | 31 | 35 | 4 | 4 | 1 |
KIF1B_ENST00000377086 | KIF1B | O60333 | Kinesin-like protein KIF1B | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 253 | 633 | 106 | 106 | 1 |
KPNB1 | KPNB1 | Q14974 | Importin subunit beta-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 92 | 94 | 11 | 11 | 0 |
LAMP2_ENST00000200639 | LAMP2 | P13473 | Lysosome-associated membrane glycoprotein 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 55 | 7 | 7 | 1 |
LAMTOR1 | LAMTOR1 | Q6IAA8 | Ragulator complex protein LAMTOR1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 96 | 7 | 7 | 0 |
LNPK_ENST00000272748 | LNPK | Q9C0E8 | Endoplasmic reticulum junction formation protein lunapark | chr2 | Not Cancer Driver | No | 1 | hippie | 62 | 257 | 43 | 43 | 0 |
LPAR1_ENST00000358883 | LPAR1 | Q92633 | Lysophosphatidic acid receptor 1 | chr9 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 79 | 21 | 6 | 6 | 0 |
LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | Census | Yes | 1 | hippie, biogrid | 95 | 84 | 12 | 12 | 0 |
MEAK7 | MEAK7 | Q6P9B6 | MTOR-associated protein MEAK7 | chr16 | Not Cancer Driver | No | 1 | hippie | 56 | 182 | 24 | 24 | 0 |
METTL7A_ENST00000332160 | METTL7A | Q9H8H3 | Putative methyltransferase-like protein 7A | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 0 | 0 | 0 | 0 |
MICAL1_ENST00000358807 | MICAL1 | Q8TDZ2 | [F-actin]-monooxygenase MICAL1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 112 | 364 | 37 | 37 | 0 |
MVB12A | MVB12A | Q96EY5 | Multivesicular body subunit 12A | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 67 | 4 | 4 | 0 |
MVB12B | MVB12B | Q9H7P6 | Multivesicular body subunit 12B | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 148 | 10 | 10 | 0 |
NCAM1_ENST00000316851 | NCAM1 | P13591 | Neural cell adhesion molecule 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 207 | 290 | 70 | 70 | 0 |
NDN | NDN | Q99608 | Necdin | chr15 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 123 | 117 | 42 | 42 | 0 |
NEDD4L | NEDD4L | Q96PU5 | E3 ubiquitin-protein ligase NEDD4-like | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 126 | 463 | 60 | 60 | 4 |
NFE2L2 | NFE2L2 | Q16236 | Nuclear factor erythroid 2-related factor 2 | chr2 | Census, Compendium | Yes | 1 | intact, hippie | 228 | 402 | 62 | 62 | 4 |
NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | Compendium | Yes | 1 | hippie, biogrid | 146 | 211 | 31 | 31 | 0 |
OGDH | OGDH | Q02218 | 2-oxoglutarate dehydrogenase complex component E1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 150 | 106 | 19 | 19 | 0 |
OPRL1_ENST00000336866 | OPRL1 | P41146 | Nociceptin receptor | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 0 | 0 | 0 | 0 |
OTULINL | OTULINL | Q9NUU6 | Inactive ubiquitin thioesterase OTULINL | chr5 | Not Cancer Driver | No | 1 | hippie | 59 | 21 | 0 | 0 | 0 |
P2RY1 | P2RY1 | P47900 | P2Y purinoceptor 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 16 | 1 | 1 | 0 |
P2RY6_ENST00000540342 | P2RY6 | Q15077 | P2Y purinoceptor 6 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 10 | 5 | 5 | 0 |
PACSIN3_ENST00000298838 | PACSIN3 | Q9UKS6 | Protein kinase C and casein kinase substrate in neurons protein 3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 290 | 31 | 31 | 0 |
PAG1 | PAG1 | Q9NWQ8 | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 394 | 54 | 54 | 0 |
PALM | PALM | O75781 | Paralemmin-1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 381 | 50 | 50 | 0 |
PALM2-AKAP2 | PALM2-AKAP2 | Q9Y2D5-4 | Isoform 3 of A-kinase anchor protein 2 | chr9 | Not Cancer Driver | No | 1 | biogrid | 179 | 1072 | 178 | 178 | 0 |
PEX6 | PEX6 | Q13608 | Peroxisome assembly factor 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 72 | 177 | 9 | 9 | 11 |
PILRB | PILRB | Q9UKJ0 | Paired immunoglobulin-like type 2 receptor beta | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 26 | 3 | 3 | 0 |
PLEC | PLEC | Q15149 | Plectin | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 677 | 2130 | 272 | 272 | 2 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
POMK | POMK | Q9H5K3 | Protein O-mannose kinase | chr8 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 53 | 30 | 9 | 9 | 3 |
PPP2R5E | PPP2R5E | Q16537 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 86 | 20 | 20 | 0 |
PRKAA1_ENST00000397128 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 124 | 17 | 17 | 0 |
PRKAA2 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 128 | 98 | 26 | 26 | 0 |
PRKCA | PRKCA | P17252 | Protein kinase C alpha type | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 94 | 154 | 22 | 22 | 0 |
PRRC1_ENST00000296666 | PRRC1 | Q96M27 | Protein PRRC1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 235 | 24 | 24 | 0 |
PSMD14 | PSMD14 | O00487 | 26S proteasome non-ATPase regulatory subunit 14 | chr2 | Not Cancer Driver | No | 1 | hippie | 23 | 67 | 6 | 6 | 0 |
PTPN11_ENST00000351677 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | Census, Compendium | Yes | 1 | hippie, biogrid | 129 | 260 | 38 | 38 | 60 |
PTPN5 | PTPN5 | P54829 | Tyrosine-protein phosphatase non-receptor type 5 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 101 | 163 | 32 | 32 | 0 |
PTPRA_ENST00000399903 | PTPRA | P18433 | Receptor-type tyrosine-protein phosphatase alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 98 | 210 | 21 | 21 | 0 |
PTPRE | PTPRE | P23469 | Receptor-type tyrosine-protein phosphatase epsilon | chr10 | Not Cancer Driver | No | 1 | hippie | 122 | 97 | 13 | 13 | 0 |
PTPRG | PTPRG | P23470 | Receptor-type tyrosine-protein phosphatase gamma | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 212 | 465 | 61 | 61 | 0 |
PYGB | PYGB | P11216 | Glycogen phosphorylase, brain form | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 118 | 29 | 5 | 5 | 0 |
RAB5IF_ENST00000373852 | RAB5IF | Q9BUV8 | Respirasome Complex Assembly Factor 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 7 | 13 | 0 | 0 | 0 |
RAB9A | RAB9A | P51151 | Ras-related protein Rab-9A | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 21 | 1 | 1 | 0 |
RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 2 |
RAVER1_ENST00000615032 | RAVER1 | Q8IY67 | Ribonucleoprotein PTB-binding 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 330 | 22 | 22 | 0 |
RELL1_ENST00000314117 | RELL1 | Q8IUW5 | RELT-like protein 1 | chr4 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 19 | 201 | 11 | 11 | 0 |
RET | RET | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret | chr10 | Census, Compendium | Yes | 1 | hippie | 208 | 105 | 12 | 12 | 139 |
RETREG3 | RETREG3 | Q86VR2 | Reticulophagy regulator 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 42 | 248 | 29 | 29 | 0 |
RFTN1 | RFTN1 | Q14699 | Raftlin | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 87 | 319 | 44 | 44 | 0 |
RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
ROCK1 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 184 | 780 | 103 | 103 | 0 |
RPN1 | RPN1 | P04843 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | chr3 | Census | Yes | 1 | hippie, biogrid | 50 | 69 | 3 | 3 | 0 |
RPN2 | RPN2 | P04844 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 26 | 4 | 4 | 0 |
S1PR4 | S1PR4 | O95977 | Sphingosine 1-phosphate receptor 4 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 11 | 2 | 2 | 0 |
SEC61B | SEC61B | P60468 | Protein transport protein Sec61 subunit beta | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 60 | 7 | 7 | 0 |
SEC62 | SEC62 | Q99442 | Translocation protein SEC62 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 211 | 23 | 23 | 0 |
SGCZ | SGCZ | Q96LD1 | Zeta-sarcoglycan | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 131 | 58 | 15 | 15 | 0 |
SLC15A3 | SLC15A3 | Q8IY34 | Solute carrier family 15 member 3 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 63 | 43 | 1 | 1 | 0 |
SLC19A2 | SLC19A2 | O60779 | Thiamine transporter 1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 61 | 17 | 6 | 6 | 3 |
SLC22A1 | SLC22A1 | O15245 | Solute carrier family 22 member 1 | chr6 | Not Cancer Driver | No | 2 | intact, hippie | 68 | 12 | 0 | 0 | 0 |
SLC39A1_ENST00000310483 | SLC39A1 | Q9NY26 | Zinc transporter ZIP1 | chr1 | Not Cancer Driver | No | 1 | hippie | 38 | 22 | 0 | 0 | 0 |
SMPDL3B | SMPDL3B | Q92485 | Acid sphingomyelinase-like phosphodiesterase 3b | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 22 | 7 | 7 | 0 |
SNAP23 | SNAP23 | O00161 | Synaptosomal-associated protein 23 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 179 | 16 | 16 | 0 |
SPTAN1_ENST00000372731 | SPTAN1 | Q13813 | Spectrin alpha chain, non-erythrocytic 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 315 | 980 | 114 | 114 | 0 |
SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | Census | Yes | 1 | hippie, biogrid | 53 | 130 | 11 | 11 | 1 |
SSR1 | SSR1 | P43307 | Translocon-associated protein subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 114 | 10 | 10 | 0 |
STXBP2_ENST00000221283 | STXBP2 | Q15833 | Syntaxin-binding protein 2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 80 | 13 | 13 | 5 |
SYAP1 | SYAP1 | Q96A49 | Synapse-associated protein 1 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 221 | 22 | 22 | 0 |
SYVN1 | SYVN1 | Q86TM6 | E3 ubiquitin-protein ligase synoviolin | chr11 | Not Cancer Driver | No | 1 | hippie | 63 | 284 | 32 | 32 | 0 |
TACR1 | TACR1 | P25103 | Substance-P receptor | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 69 | 28 | 2 | 2 | 0 |
TCTN2 | TCTN2 | Q96GX1 | Tectonic-2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 75 | 23 | 2 | 2 | 0 |
TCTN3 | TCTN3 | Q6NUS6 | Tectonic-3 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 45 | 71 | 8 | 8 | 1 |
TECR | TECR | Q9NZ01 | Very-long-chain enoyl-CoA reductase | chr19 | Not Cancer Driver | No | 1 | hippie | 41 | 0 | 0 | 0 | 1 |
TJP1_ENST00000346128 | TJP1 | Q07157 | Tight junction protein ZO-1 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 198 | 1350 | 151 | 151 | 0 |
TLN1 | TLN1 | Q9Y490 | Talin-1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 278 | 1109 | 126 | 126 | 0 |
TMBIM6_ENST00000549385 | TMBIM6 | P55061 | Bax inhibitor 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 16 | 3 | 0 | 0 | 0 |
TMEM106B | TMEM106B | Q9NUM4 | Transmembrane protein 106B | chr7 | Not Cancer Driver | No | 1 | hippie | 31 | 56 | 4 | 4 | 1 |
TMEM216 | TMEM216 | Q9P0N5 | Transmembrane protein 216 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 11 | 0 | 0 | 0 | 7 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
TRIP12_ENST00000283943 | TRIP12 | Q14669 | E3 ubiquitin-protein ligase TRIP12 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 224 | 845 | 117 | 117 | 4 |
TSG101 | TSG101 | Q99816 | Tumor susceptibility gene 101 protein | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 159 | 23 | 23 | 0 |
TSPAN15 | TSPAN15 | O95858 | Tetraspanin-15 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 0 | 0 | 0 | 0 |
TTYH1_ENST00000376530 | TTYH1 | Q9H313 | Protein tweety homolog 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 21 | 3 | 3 | 0 |
UBQLN2 | UBQLN2 | Q9UHD9 | Ubiquilin-2 | chrX | Not Cancer Driver | No | 1 | hippie | 82 | 581 | 79 | 79 | 8 |
ULBP3 | ULBP3 | Q9BZM4 | UL16-binding protein 3 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 14 | 1 | 1 | 0 |
UNC93B1 | UNC93B1 | Q9H1C4 | Protein unc-93 homolog B1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 57 | 127 | 5 | 5 | 0 |
VIM_ENST00000224237 | VIM | P08670 | Vimentin | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 316 | 57 | 57 | 1 |
VIPR1 | VIPR1 | P32241 | Vasoactive intestinal polypeptide receptor 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 10 | 2 | 2 | 0 |
VIPR2 | VIPR2 | P41587 | Vasoactive intestinal polypeptide receptor 2 | chr7 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 74 | 0 | 0 | 0 | 0 |
VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
VPS26A_ENST00000263559 | VPS26A | O75436 | Vacuolar protein sorting-associated protein 26A | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 44 | 2 | 2 | 0 |
VPS28_ENST00000292510 | VPS28 | Q9UK41 | Vacuolar protein sorting-associated protein 28 homolog | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 31 | 5 | 5 | 0 |
VPS37C | VPS37C | A5D8V6 | Vacuolar protein sorting-associated protein 37C | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 309 | 31 | 31 | 0 |
YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 489 | 49 | 49 | 0 |
YES1_ENST00000314574 | YES1 | P07947 | Tyrosine-protein kinase Yes | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 62 | 10 | 10 | 0 |
YIF1A | YIF1A | O95070 | Protein YIF1A | chr11 | Not Cancer Driver | No | 1 | hippie | 32 | 33 | 3 | 3 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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