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CEP350 ,CEP350 ,Q5VT06
  • Number of Interaction partner in intact: 28
  • Number of Interaction partner in biogrid: 50
  • Number of Interaction partner in hippie: 117
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 Not Cancer Driver No 1 hippie, biogrid 32 16 2 2 0
AMOT AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 1 hippie, biogrid 161 909 128 128 0
ANAPC2 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 Not Cancer Driver No 1 hippie, biogrid 104 146 26 26 0
AP2B1_ENST00000621914 AP2B1 P63010 AP-2 complex subunit beta chr17 Not Cancer Driver No 1 hippie, biogrid 85 95 12 12 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 intact, hippie 128 418 71 71 17
APTX_ENST00000379819 APTX Q7Z2E3 Aprataxin chr9 Not Cancer Driver No 1 hippie 36 101 6 6 9
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 Not Cancer Driver No 1 hippie 63 327 55 55 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 Not Cancer Driver No 1 intact, hippie 66 23 5 5 2
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
CAMSAP2 CAMSAP2 Q08AD1 Calmodulin-regulated spectrin-associated protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 176 1025 127 127 0
CBX6 CBX6 O95503 Chromobox protein homolog 6 chr22 Not Cancer Driver No 1 intact, hippie 57 335 54 54 0
CCDC13 CCDC13 Q8IYE1 Coiled-coil domain-containing protein 13 chr3 Not Cancer Driver No 1 intact, hippie 114 580 95 95 0
CCDC14 CCDC14 Q49A88-6 Isoform 6 of Coiled-coil domain-containing protein 14 chr3 Not Cancer Driver No 1 hippie, biogrid 88 585 61 61 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CCDC85A CCDC85A Q96PX6 Coiled-coil domain-containing protein 85A chr2 Not Cancer Driver No 1 hippie, biogrid 146 399 116 116 0
CCDC96 CCDC96 Q2M329 Coiled-coil domain-containing protein 96 chr4 Not Cancer Driver No 1 hippie, biogrid 74 308 41 41 0
CDC14A_ENST00000336454 CDC14A Q9UNH5 Dual specificity protein phosphatase CDC14A chr1 Not Cancer Driver No 1 intact, hippie 91 246 43 43 3
CDC16_ENST00000356221 CDC16 Q13042 Cell division cycle protein 16 homolog chr13 Not Cancer Driver No 2 intact, hippie, biogrid 68 54 7 7 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 Not Cancer Driver No 1 hippie, biogrid 217 1136 128 128 0
CEP104 CEP104 O60308 Centrosomal protein of 104 kDa chr1 Not Cancer Driver No 1 hippie 116 306 43 43 0
CEP120 CEP120 Q8N960 Centrosomal protein of 120 kDa chr5 Not Cancer Driver No 1 hippie 102 448 52 52 1
CEP128_ENST00000281129 CEP128 Q6ZU80 Centrosomal protein of 128 kDa chr14 Not Cancer Driver No 1 hippie 195 897 167 167 0
CEP135 CEP135 Q66GS9 Centrosomal protein of 135 kDa chr4 Not Cancer Driver No 2 hippie, biogrid 127 690 72 72 0
CEP152 CEP152 O94986 Centrosomal protein of 152 kDa chr15 Not Cancer Driver No 1 hippie 204 986 110 110 2
CEP19 CEP19 Q96LK0 Centrosomal protein of 19 kDa chr3 Not Cancer Driver No 2 intact, hippie, biogrid 30 71 11 11 0
CEP192 CEP192 Q8TEP8 Centrosomal protein of 192 kDa chr18 Not Cancer Driver No 1 hippie 274 1214 110 110 0
CEP250 CEP250 Q9BV73 Centrosome-associated protein CEP250 chr20 Not Cancer Driver No 1 hippie 250 1859 195 195 0
CEP290 CEP290 O15078 Centrosomal protein of 290 kDa chr12 Not Cancer Driver No 1 intact, hippie 255 1421 152 152 3
CEP63 CEP63 Q96MT8 Centrosomal protein of 63 kDa chr3 Not Cancer Driver No 1 intact, hippie 100 507 68 68 0
CEP78_ENST00000424347 CEP78 Q5JTW2 Centrosomal protein of 78 kDa chr9 Not Cancer Driver No 1 hippie 79 295 32 32 0
CEP85 CEP85 Q6P2H3 Centrosomal protein of 85 kDa chr1 Not Cancer Driver No 1 hippie 77 607 60 60 0
CEP89 CEP89 Q96ST8 Centrosomal protein of 89 kDa chr19 Census Yes 1 hippie 96 540 72 72 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 Compendium Yes 1 hippie 42 30 0 0 0
CNTRL_ENST00000238341 CNTRL Q7Z7A1 Centriolin chr9 Census Yes 1 hippie 234 1556 159 159 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 Census Yes 2 hippie, biogrid 126 268 35 35 4
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 Census Yes 1 hippie, biogrid 172 817 111 111 11
DCTN2_ENST00000548249 DCTN2 Q13561 Dynactin subunit 2 chr12 Not Cancer Driver No 1 hippie, biogrid 46 253 32 32 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 2 intact, hippie, biogrid 132 514 82 82 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 Compendium Yes 1 hippie, biogrid 70 273 34 34 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
FAM160B1 FHIP2A Q5W0V3 FHF complex subunit HOOK interacting protein 2A chr10 Not Cancer Driver No 1 intact 92 130 13 13 0
FGFR1OP CEP43 O95684 Centrosomal protein 43 chr6 Not Cancer Driver No 3 intact 43 272 33 33 0
GOLGA1 GOLGA1 Q92805 Golgin subfamily A member 1 chr9 Not Cancer Driver No 1 hippie, biogrid 99 582 77 77 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 intact, hippie 56 146 13 13 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie 37 77 9 9 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 118 435 51 51 0
HOOK2 HOOK2 Q96ED9 Protein Hook homolog 2 chr19 Not Cancer Driver No 1 intact 94 487 62 62 0
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie 45 71 9 9 0
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 hippie, biogrid 67 291 28 28 3
KIAA0753 KIAA0753 Q2KHM9 Protein moonraker chr17 Not Cancer Driver No 1 intact, hippie 109 647 82 82 0
KIF11 KIF11 P52732 Kinesin-like protein KIF11 chr10 Not Cancer Driver No 1 intact, hippie 90 389 26 26 4
KIF1B_ENST00000377086 KIF1B O60333 Kinesin-like protein KIF1B chr1 Not Cancer Driver No 1 hippie 253 633 106 106 1
KIF22 KIF22 Q14807 Kinesin-like protein KIF22 chr16 Not Cancer Driver No 1 hippie 79 322 35 35 4
KIFAP3 KIFAP3 Q92845 Kinesin-associated protein 3 chr1 Not Cancer Driver No 1 hippie 116 71 10 10 0
KRT18_ENST00000388837 KRT18 P05783 Keratin, type I cytoskeletal 18 chr12 Not Cancer Driver No 1 hippie, biogrid 57 179 21 21 4
KRT19 KRT19 P08727 Keratin, type I cytoskeletal 19 chr17 Not Cancer Driver No 1 hippie, biogrid 57 165 19 19 0
KRT2 KRT2 P35908 Keratin, type II cytoskeletal 2 epidermal chr12 Not Cancer Driver No 1 hippie, biogrid 122 335 59 59 15
KRT8_ENST00000546897 KRT8 P05787 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 1 hippie, biogrid 65 221 37 37 3
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 Census, Compendium Yes 1 hippie, biogrid 161 788 100 100 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 intact, hippie 62 2 0 0 7
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 Not Cancer Driver No 2 hippie, biogrid 26 109 11 11 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 Not Cancer Driver No 1 hippie, biogrid 37 120 16 16 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 hippie, biogrid 136 589 92 92 0
MED4 MED4 Q9NPJ6 Mediator of RNA polymerase II transcription subunit 4 chr13 Not Cancer Driver No 1 hippie 29 161 17 17 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
NCKAP5 NCKAP5 O14513 Nck-associated protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 450 1677 408 408 0
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 Not Cancer Driver No 1 hippie, biogrid 80 313 45 45 0
NEURL4 NEURL4 Q96JN8 Neuralized-like protein 4 chr17 Not Cancer Driver No 1 intact, hippie 217 751 119 119 0
NIN NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 239 1392 164 164 2
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 intact, hippie 230 881 150 150 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 Not Cancer Driver No 1 hippie 56 146 13 13 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NUP98_ENST00000359171 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 Census Yes 1 hippie 227 1008 107 107 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OFD1 OFD1 O75665 Oral-facial-digital syndrome 1 protein chrX Not Cancer Driver No 1 hippie 129 476 58 58 5
PCDH7_ENST00000361762 PCDH7 O60245 Protocadherin-7 chr4 Not Cancer Driver No 1 intact, hippie 167 550 76 76 0
PCM1 PCM1 Q15154 Pericentriolar material 1 protein chr8 Census Yes 2 intact, hippie, biogrid 152 1665 134 134 0
PCNT PCNT O95613 Pericentrin chr21 Not Cancer Driver No 1 hippie, biogrid 436 2474 337 337 0
PFN1 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie, biogrid 16 7 1 1 3
PIP PIP P12273 Prolactin-inducible protein chr7 Not Cancer Driver No 1 hippie, biogrid 42 0 0 0 0
PLEKHA5_ENST00000299275 PLEKHA5 Q9HAU0 Pleckstrin homology domain-containing family A member 5 chr12 Not Cancer Driver No 1 intact, hippie 144 869 114 114 0
PLK4 PLK4 O00444 Serine/threonine-protein kinase PLK4 chr4 Not Cancer Driver No 1 hippie 102 451 45 45 0
PNMA2 PNMA2 Q9UL42 Paraneoplastic antigen Ma2 chr8 Not Cancer Driver No 1 hippie, biogrid 52 45 5 5 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 Not Cancer Driver No 1 hippie 63 68 9 9 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 Not Cancer Driver No 1 hippie 72 69 7 7 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 72 44 4 4 3
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 1 hippie 41 12 1 1 8
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 Not Cancer Driver No 4 intact, hippie, biogrid 37 12 0 0 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 3 intact, hippie, biogrid 179 0 0 0 4
PPP2R3C PPP2R3C Q969Q6 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma chr14 Not Cancer Driver No 1 hippie 44 30 3 3 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 hippie, biogrid 62 341 24 24 0
RABL2B_ENST00000435118 RABL2B Q9UNT1 Rab-like protein 2B chr22 Not Cancer Driver No 1 hippie, biogrid 19 45 4 4 0
RITA1_ENST00000548278 RITA1 Q96K30 RBPJ-interacting and tubulin-associated protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 27 271 28 28 0
RNF10_ENST00000325954 RNF10 Q8N5U6 RING finger protein 10 chr12 Not Cancer Driver No 1 hippie, biogrid 108 455 63 63 0
RPGRIP1L_ENST00000379925 RPGRIP1L Q68CZ1 Protein fantom chr16 Not Cancer Driver No 1 intact, hippie 177 586 94 94 8
S100A2_ENST00000368709 S100A2 P29034 Protein S100-A2 chr1 Not Cancer Driver No 1 hippie, biogrid 16 6 2 2 0
SAMD4B SAMD4B Q5PRF9 Protein Smaug homolog 2 chr19 Not Cancer Driver No 1 hippie 79 467 57 57 0
SASS6 SASS6 Q6UVJ0 Spindle assembly abnormal protein 6 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 82 331 37 37 1
SPATA2_ENST00000289431 SPATA2 Q9UM82 Spermatogenesis-associated protein 2 chr20 Not Cancer Driver No 1 hippie 70 235 39 39 0
SPICE1 SPICE1 Q8N0Z3 Spindle and centriole-associated protein 1 chr3 Not Cancer Driver No 1 hippie 112 729 92 92 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 2 hippie, biogrid 54 267 32 32 30
SSX2IP SSX2IP Q9Y2D8 Afadin- and alpha-actinin-binding protein chr1 Not Cancer Driver No 1 intact, hippie 82 265 31 31 0
STIL_ENST00000360380 STIL Q15468 SCL-interrupting locus protein chr1 Census, Compendium Yes 1 hippie, biogrid 147 735 85 85 1
SYNE3 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 143 236 42 42 0
TDRD3_ENST00000196169 TDRD3 Q9H7E2 Tudor domain-containing protein 3 chr13 Not Cancer Driver No 1 hippie 97 518 77 77 0
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 intact, hippie 254 781 156 156 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TPTE2 TPTE2 Q6XPS3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 chr13 Not Cancer Driver No 1 hippie 210 33 13 13 0
TRIM36 TRIM36 Q9NQ86 E3 ubiquitin-protein ligase TRIM36 chr5 Not Cancer Driver No 1 hippie, biogrid 106 89 21 21 1
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
TRIM52 TRIM52 Q96A61 E3 ubiquitin-protein ligase TRIM52 chr5 Not Cancer Driver No 1 hippie, biogrid 23 147 13 13 0
VASP VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 1 hippie, biogrid 39 335 34 34 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VPS33B VPS33B Q9H267 Vacuolar protein sorting-associated protein 33B chr15 Not Cancer Driver No 1 hippie 54 17 0 0 2
WEE1 WEE1 P30291 Wee1-like protein kinase chr11 Not Cancer Driver No 1 intact, hippie 60 399 27 27 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
ZYX ZYX Q15942 Zyxin chr7 Not Cancer Driver No 1 hippie, biogrid 83 385 52 52 0