Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACER3 | ACER3 | Q9NUN7 | Alkaline ceramidase 3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 0 | 0 | 0 | 1 |
| ACTC1 | ACTC1 | P68032 | Actin, alpha cardiac muscle 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 114 | 48 | 19 | 19 | 11 |
| ALK | ALK | Q9UM73 | ALK tyrosine kinase receptor | chr2 | Census, Compendium | Yes | 2 | intact, hippie | 303 | 575 | 114 | 114 | 16 |
| ANLN | ANLN | Q9NQW6 | Anillin | chr7 | Not Cancer Driver | No | 1 | hippie | 144 | 767 | 104 | 104 | 2 |
| APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 103 | 14 | 14 | 0 |
| ARRB2_ENST00000269260 | ARRB2 | P32121 | Beta-arrestin-2 | chr17 | Not Cancer Driver | No | 1 | hippie | 46 | 122 | 22 | 22 | 0 |
| ASF1A | ASF1A | Q9Y294 | Histone chaperone ASF1A | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 69 | 2 | 2 | 0 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
| BRAP | BRAP | Q7Z569 | BRCA1-associated protein | chr12 | Not Cancer Driver | No | 1 | hippie | 70 | 192 | 24 | 24 | 0 |
| BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 224 | 1458 | 174 | 174 | 35 |
| BRK1 | BRK1 | Q8WUW1 | Protein BRICK1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 14 | 1 | 1 | 0 |
| CBX4 | CBX4 | O00257 | E3 SUMO-protein ligase CBX4 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 72 | 477 | 63 | 63 | 0 |
| CCDC33_ENST00000558821 | CCDC33 | Q8N5R6-4 | Isoform 4 of Coiled-coil domain-containing protein 33 | chr15 | Not Cancer Driver | No | 2 | hippie, biogrid | 60 | 288 | 51 | 51 | 0 |
| CCDC68_ENST00000432185 | CCDC68 | Q9H2F9 | Coiled-coil domain-containing protein 68 | chr18 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 77 | 205 | 45 | 45 | 0 |
| CDCA5 | CDCA5 | Q96FF9 | Sororin | chr11 | Not Cancer Driver | No | 1 | hippie | 32 | 211 | 26 | 26 | 0 |
| CDK1 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 40 | 1 | 0 | 0 | 0 |
| CENPE | CENPE | Q02224 | Centromere-associated protein E | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 343 | 1620 | 228 | 228 | 2 |
| CENPF | CENPF | P49454 | Centromere protein F | chr1 | Not Cancer Driver | No | 1 | hippie | 387 | 2136 | 260 | 260 | 0 |
| CENPU | CENPU | Q71F23 | Centromere protein U | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 51 | 298 | 42 | 42 | 0 |
| CHMP2B | CHMP2B | Q9UQN3 | Charged multivesicular body protein 2b | chr3 | Not Cancer Driver | No | 1 | hippie | 28 | 183 | 25 | 25 | 4 |
| CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
| COG6 | COG6 | Q9Y2V7 | Conserved oligomeric Golgi complex subunit 6 | chr13 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 83 | 141 | 16 | 16 | 1 |
| COPS6 | COPS6 | Q7L5N1 | COP9 signalosome complex subunit 6 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 38 | 30 | 6 | 6 | 0 |
| CTNNA1 | CTNNA1 | P35221 | Catenin alpha-1 | chr5 | Census | Yes | 1 | hippie, biogrid | 126 | 268 | 35 | 35 | 4 |
| CUL4A | CUL4A | Q13619 | Cullin-4A | chr13 | Not Cancer Driver | No | 1 | hippie | 64 | 102 | 2 | 2 | 0 |
| CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | Not Cancer Driver | No | 1 | hippie | 188 | 372 | 41 | 41 | 3 |
| DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 132 | 514 | 82 | 82 | 0 |
| DYRK1A_ENST00000644942 | DYRK1A | Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | chr21 | Not Cancer Driver | No | 1 | hippie | 135 | 447 | 73 | 73 | 0 |
| EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
| ERP29 | ERP29 | P30040 | Endoplasmic reticulum resident protein 29 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 29 | 34 | 5 | 5 | 0 |
| ESAM | ESAM | Q96AP7 | Endothelial cell-selective adhesion molecule | chr11 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 54 | 154 | 30 | 30 | 0 |
| ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
| FAM160A2_ENST00000449352 | FHIP1B | Q8N612 | FHF complex subunit HOOK interacting protein 1B | chr11 | Not Cancer Driver | No | 1 | intact | 129 | 415 | 54 | 54 | 0 |
| FAM167A | FAM167A | Q96KS9 | Protein FAM167A | chr8 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 33 | 116 | 17 | 17 | 0 |
| FBXL5 | FBXL5 | Q9UKA1 | F-box/LRR-repeat protein 5 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 70 | 7 | 7 | 0 |
| FBXO38_ENST00000340253 | FBXO38 | Q6PIJ6 | F-box only protein 38 | chr5 | Not Cancer Driver | No | 1 | hippie | 133 | 440 | 48 | 48 | 1 |
| FNTA | FNTA | P49354 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | chr8 | Not Cancer Driver | No | 2 | hippie, biogrid | 43 | 92 | 12 | 12 | 0 |
| FNTB | FNTB | P49356 | Protein farnesyltransferase subunit beta | chr14 | Not Cancer Driver | No | 4 | hippie, biogrid | 36 | 31 | 1 | 1 | 0 |
| G3BP1 | G3BP1 | Q13283 | Ras GTPase-activating protein-binding protein 1 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 85 | 352 | 65 | 65 | 0 |
| GOPC | GOPC | Q9HD26 | Golgi-associated PDZ and coiled-coil motif-containing protein | chr6 | Census | Yes | 2 | intact, hippie, biogrid | 56 | 263 | 34 | 34 | 0 |
| HECW2_ENST00000644256 | HECW2 | Q9P2P5 | E3 ubiquitin-protein ligase HECW2 | chr2 | Not Cancer Driver | No | 1 | hippie | 348 | 845 | 195 | 195 | 4 |
| HIST1H1A | H1-1 | Q02539 | Histone H1.1 | chr6 | Not Cancer Driver | No | 1 | intact | 37 | 210 | 35 | 35 | 0 |
| IKBKG_ENST00000611071 | IKBKG | Q9Y6K9 | NF-kappa-B essential modulator | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 6 | 301 | 6 | 6 | 22 |
| JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
| KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 774 | 102 | 102 | 2 |
| KPNA1 | KPNA1 | P52294 | Importin subunit alpha-5 | chr3 | Not Cancer Driver | No | 1 | hippie | 65 | 121 | 18 | 18 | 0 |
| KXD1_ENST00000222307 | KXD1 | Q9BQD3 | KxDL motif-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 104 | 17 | 17 | 0 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
| MAGEA3 | MAGEA3 | P43357 | Melanoma-associated antigen 3 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 79 | 103 | 18 | 18 | 0 |
| MAP7D2_ENST00000379651 | MAP7D2 | Q96T17 | MAP7 domain-containing protein 2 | chrX | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 124 | 723 | 120 | 120 | 0 |
| MAPRE3 | MAPRE3 | Q9UPY8 | Microtubule-associated protein RP/EB family member 3 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 120 | 16 | 16 | 0 |
| MKI67 | MKI67 | P46013 | Proliferation marker protein Ki-67 | chr10 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 540 | 3169 | 529 | 529 | 0 |
| MRFAP1L1 | MRFAP1L1 | Q96HT8 | MORF4 family-associated protein 1-like 1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 59 | 5 | 5 | 0 |
| MTCH2 | MTCH2 | Q9Y6C9 | Mitochondrial carrier homolog 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 11 | 0 | 0 | 0 |
| MTMR9 | MTMR9 | Q96QG7 | Myotubularin-related protein 9 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 45 | 7 | 7 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
| MZT1 | MZT1 | Q08AG7 | Mitotic-spindle organizing protein 1 | chr13 | Not Cancer Driver | No | 1 | hippie | 13 | 9 | 3 | 3 | 0 |
| NANOG | NANOG | Q9H9S0 | Homeobox protein NANOG | chr12 | Not Cancer Driver | No | 1 | hippie | 46 | 169 | 35 | 35 | 0 |
| NDE1_ENST00000396354 | NDE1 | Q9NXR1 | Nuclear distribution protein nudE homolog 1 | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 45 | 316 | 42 | 42 | 0 |
| NDEL1 | NDEL1 | Q9GZM8 | Nuclear distribution protein nudE-like 1 | chr17 | Not Cancer Driver | No | 3 | intact, hippie | 32 | 202 | 16 | 16 | 0 |
| NEURL4 | NEURL4 | Q96JN8 | Neuralized-like protein 4 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 217 | 751 | 119 | 119 | 0 |
| NFKBIA | NFKBIA | P25963 | NF-kappa-B inhibitor alpha | chr14 | Compendium | Yes | 1 | intact, hippie | 37 | 102 | 9 | 9 | 1 |
| NPM1 | NPM1 | P06748 | Nucleophosmin | chr5 | Census, Compendium | Yes | 1 | hippie | 29 | 249 | 22 | 22 | 0 |
| NQO2_ENST00000380430 | NQO2 | P16083 | Ribosyldihydronicotinamide dehydrogenase [quinone] | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 10 | 1 | 1 | 0 |
| NUP107 | NUP107 | P57740 | Nuclear pore complex protein Nup107 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 127 | 183 | 26 | 26 | 5 |
| NUP133 | NUP133 | Q8WUM0 | Nuclear pore complex protein Nup133 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 143 | 116 | 16 | 16 | 3 |
| OBSL1 | OBSL1 | O75147 | Obscurin-like protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 233 | 553 | 60 | 60 | 0 |
| PAFAH1B1 | PAFAH1B1 | P43034 | Platelet-activating factor acetylhydrolase IB subunit beta | chr17 | Not Cancer Driver | No | 1 | hippie | 42 | 82 | 11 | 11 | 7 |
| PCLAF | PCLAF | Q15004 | PCNA-associated factor | chr15 | Not Cancer Driver | No | 1 | hippie | 20 | 111 | 20 | 20 | 0 |
| POLH | POLH | Q9Y253 | DNA polymerase eta | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 72 | 291 | 20 | 20 | 10 |
| PPP1R13B | PPP1R13B | Q96KQ4 | Apoptosis-stimulating of p53 protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 115 | 821 | 92 | 92 | 0 |
| PRC1 | PRC1 | O43663 | Protein regulator of cytokinesis 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 63 | 235 | 26 | 26 | 0 |
| RDX_ENST00000343115 | RDX | P35241 | Radixin | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 297 | 37 | 37 | 1 |
| RHOT2 | RHOT2 | Q8IXI1 | Mitochondrial Rho GTPase 2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 79 | 5 | 5 | 0 |
| RMDN3 | RMDN3 | Q96TC7 | Regulator of microtubule dynamics protein 3 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 196 | 17 | 17 | 0 |
| RNF123 | RNF123 | Q5XPI4 | E3 ubiquitin-protein ligase RNF123 | chr3 | Not Cancer Driver | No | 1 | hippie | 167 | 220 | 28 | 28 | 0 |
| RNF166 | RNF166 | Q96A37 | E3 ubiquitin-protein ligase RNF166 | chr16 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 18 | 24 | 2 | 2 | 0 |
| RPL31_ENST00000264258 | RPL31 | P62899 | 60S ribosomal protein L31 | chr2 | Not Cancer Driver | No | 1 | hippie | 19 | 69 | 14 | 14 | 0 |
| SETD2 | SETD2 | Q9BYW2 | Histone-lysine N-methyltransferase SETD2 | chr3 | Census, Compendium | Yes | 1 | hippie | 321 | 1945 | 209 | 209 | 2 |
| SIRT7 | SIRT7 | Q9NRC8 | NAD-dependent protein deacetylase sirtuin-7 | chr17 | Not Cancer Driver | No | 1 | hippie | 48 | 163 | 15 | 15 | 0 |
| SLC16A11 | SLC16A11 | Q8NCK7 | Monocarboxylate transporter 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 33 | 72 | 5 | 5 | 0 |
| SLFN11_ENST00000308377 | SLFN11 | Q7Z7L1 | Schlafen family member 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 177 | 34 | 8 | 8 | 0 |
| SNAP25 | SNAP25 | P60880 | Synaptosomal-associated protein 25 | chr20 | Not Cancer Driver | No | 1 | hippie | 61 | 176 | 49 | 49 | 1 |
| SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
| SVIL | SVIL | O95425 | Supervillin | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 308 | 1423 | 192 | 192 | 0 |
| SYCE1_ENST00000343131 | SYCE1 | Q8N0S2 | Synaptonemal complex central element protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 251 | 50 | 50 | 0 |
| TCP10L | TCP10L | Q8TDR4 | T-complex protein 10A homolog 1 | chr21 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 32 | 213 | 32 | 32 | 0 |
| TERF1 | TERF1 | P54274 | Telomeric repeat-binding factor 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 63 | 220 | 34 | 34 | 0 |
| TERF2 | TERF2 | Q15554 | Telomeric repeat-binding factor 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 33 | 361 | 20 | 20 | 0 |
| TMA16 | TMA16 | Q96EY4 | Translation machinery-associated protein 16 | chr4 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 25 | 112 | 10 | 10 | 0 |
| TOP3B_ENST00000357179 | TOP3B | O95985 | DNA topoisomerase 3-beta-1 | chr22 | Not Cancer Driver | No | 1 | hippie | 102 | 151 | 17 | 17 | 0 |
| TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 430 | 41 | 41 | 0 |
| TSC22D1 | TSC22D1 | Q15714 | TSC22 domain family protein 1 | chr13 | Not Cancer Driver | No | 1 | intact, hippie | 110 | 1023 | 98 | 98 | 0 |
| TXLNA_ENST00000373610 | TXLNA | P40222 | Alpha-taxilin | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 481 | 59 | 59 | 0 |
| VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
| WASF3 | WASF3 | Q9UPY6 | Wiskott-Aldrich syndrome protein family member 3 | chr13 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 108 | 386 | 84 | 84 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|