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CENPF ,CENPF ,P49454
  • Uniprot Accession= P49454
  • Ensembl Transcript= ENST00000366955.7
  • Uniprot Name= CENPF
  • Name= Centromere protein F
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 31
  • Number of Interaction partner in biogrid: 34
  • Number of Interaction partner in hippie: 94
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACER3 ACER3 Q9NUN7 Alkaline ceramidase 3 chr11 Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 1
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 Census, Compendium Yes 2 intact, hippie 303 575 114 114 16
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie, biogrid 34 103 14 14 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 Not Cancer Driver No 1 hippie 46 122 22 22 0
ASF1A ASF1A Q9Y294 Histone chaperone ASF1A chr6 Not Cancer Driver No 1 hippie, biogrid 18 69 2 2 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRAP BRAP Q7Z569 BRCA1-associated protein chr12 Not Cancer Driver No 1 hippie 70 192 24 24 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BRK1 BRK1 Q8WUW1 Protein BRICK1 chr3 Not Cancer Driver No 1 hippie, biogrid 7 14 1 1 0
CBX4 CBX4 O00257 E3 SUMO-protein ligase CBX4 chr17 Not Cancer Driver No 1 intact, hippie 72 477 63 63 0
CCDC33_ENST00000558821 CCDC33 Q8N5R6-4 Isoform 4 of Coiled-coil domain-containing protein 33 chr15 Not Cancer Driver No 2 hippie, biogrid 60 288 51 51 0
CCDC68_ENST00000432185 CCDC68 Q9H2F9 Coiled-coil domain-containing protein 68 chr18 Not Cancer Driver No 3 intact, hippie, biogrid 77 205 45 45 0
CDCA5 CDCA5 Q96FF9 Sororin chr11 Not Cancer Driver No 1 hippie 32 211 26 26 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 Not Cancer Driver No 1 hippie 40 1 0 0 0
CENPE CENPE Q02224 Centromere-associated protein E chr4 Not Cancer Driver No 1 intact, hippie 343 1620 228 228 2
CENPF CENPF P49454 Centromere protein F chr1 Not Cancer Driver No 1 hippie 387 2136 260 260 0
CENPU CENPU Q71F23 Centromere protein U chr4 Not Cancer Driver No 1 intact, hippie 51 298 42 42 0
CHMP2B CHMP2B Q9UQN3 Charged multivesicular body protein 2b chr3 Not Cancer Driver No 1 hippie 28 183 25 25 4
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
COG6 COG6 Q9Y2V7 Conserved oligomeric Golgi complex subunit 6 chr13 Not Cancer Driver No 1 intact, hippie, biogrid 83 141 16 16 1
COPS6 COPS6 Q7L5N1 COP9 signalosome complex subunit 6 chr7 Not Cancer Driver No 1 intact, hippie 38 30 6 6 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 Census Yes 1 hippie, biogrid 126 268 35 35 4
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 64 102 2 2 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 135 447 73 73 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
ERP29 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 Not Cancer Driver No 1 intact, hippie 29 34 5 5 0
ESAM ESAM Q96AP7 Endothelial cell-selective adhesion molecule chr11 Not Cancer Driver No 1 intact, hippie, biogrid 54 154 30 30 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FAM160A2_ENST00000449352 FHIP1B Q8N612 FHF complex subunit HOOK interacting protein 1B chr11 Not Cancer Driver No 1 intact 129 415 54 54 0
FAM167A FAM167A Q96KS9 Protein FAM167A chr8 Not Cancer Driver No 1 intact, hippie, biogrid 33 116 17 17 0
FBXL5 FBXL5 Q9UKA1 F-box/LRR-repeat protein 5 chr4 Not Cancer Driver No 1 hippie, biogrid 80 70 7 7 0
FBXO38_ENST00000340253 FBXO38 Q6PIJ6 F-box only protein 38 chr5 Not Cancer Driver No 1 hippie 133 440 48 48 1
FNTA FNTA P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha chr8 Not Cancer Driver No 2 hippie, biogrid 43 92 12 12 0
FNTB FNTB P49356 Protein farnesyltransferase subunit beta chr14 Not Cancer Driver No 4 hippie, biogrid 36 31 1 1 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 intact, hippie 85 352 65 65 0
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 Census Yes 2 intact, hippie, biogrid 56 263 34 34 0
HECW2_ENST00000644256 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 Not Cancer Driver No 1 hippie 348 845 195 195 4
HIST1H1A H1-1 Q02539 Histone H1.1 chr6 Not Cancer Driver No 1 intact 37 210 35 35 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 2 hippie, biogrid 6 301 6 6 22
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KPNA1 KPNA1 P52294 Importin subunit alpha-5 chr3 Not Cancer Driver No 1 hippie 65 121 18 18 0
KXD1_ENST00000222307 KXD1 Q9BQD3 KxDL motif-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 24 104 17 17 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
MAGEA3 MAGEA3 P43357 Melanoma-associated antigen 3 chrX Not Cancer Driver No 1 hippie, biogrid 79 103 18 18 0
MAP7D2_ENST00000379651 MAP7D2 Q96T17 MAP7 domain-containing protein 2 chrX Not Cancer Driver No 1 intact, hippie, biogrid 124 723 120 120 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 Not Cancer Driver No 1 hippie, biogrid 37 120 16 16 0
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 540 3169 529 529 0
MRFAP1L1 MRFAP1L1 Q96HT8 MORF4 family-associated protein 1-like 1 chr4 Not Cancer Driver No 1 hippie, biogrid 12 59 5 5 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie, biogrid 45 11 0 0 0
MTMR9 MTMR9 Q96QG7 Myotubularin-related protein 9 chr8 Not Cancer Driver No 1 hippie, biogrid 60 45 7 7 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MZT1 MZT1 Q08AG7 Mitotic-spindle organizing protein 1 chr13 Not Cancer Driver No 1 hippie 13 9 3 3 0
NANOG NANOG Q9H9S0 Homeobox protein NANOG chr12 Not Cancer Driver No 1 hippie 46 169 35 35 0
NDE1_ENST00000396354 NDE1 Q9NXR1 Nuclear distribution protein nudE homolog 1 chr16 Not Cancer Driver No 1 intact, hippie 45 316 42 42 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 Not Cancer Driver No 3 intact, hippie 32 202 16 16 0
NEURL4 NEURL4 Q96JN8 Neuralized-like protein 4 chr17 Not Cancer Driver No 1 intact, hippie 217 751 119 119 0
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 Compendium Yes 1 intact, hippie 37 102 9 9 1
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 29 249 22 22 0
NQO2_ENST00000380430 NQO2 P16083 Ribosyldihydronicotinamide dehydrogenase [quinone] chr6 Not Cancer Driver No 1 hippie, biogrid 28 10 1 1 0
NUP107 NUP107 P57740 Nuclear pore complex protein Nup107 chr12 Not Cancer Driver No 1 intact, hippie 127 183 26 26 5
NUP133 NUP133 Q8WUM0 Nuclear pore complex protein Nup133 chr1 Not Cancer Driver No 1 intact, hippie 143 116 16 16 3
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 Not Cancer Driver No 1 hippie 42 82 11 11 7
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
POLH POLH Q9Y253 DNA polymerase eta chr6 Not Cancer Driver No 1 intact, hippie 72 291 20 20 10
PPP1R13B PPP1R13B Q96KQ4 Apoptosis-stimulating of p53 protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 115 821 92 92 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 Not Cancer Driver No 1 hippie, biogrid 71 297 37 37 1
RHOT2 RHOT2 Q8IXI1 Mitochondrial Rho GTPase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 52 79 5 5 0
RMDN3 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 45 196 17 17 0
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 167 220 28 28 0
RNF166 RNF166 Q96A37 E3 ubiquitin-protein ligase RNF166 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 18 24 2 2 0
RPL31_ENST00000264258 RPL31 P62899 60S ribosomal protein L31 chr2 Not Cancer Driver No 1 hippie 19 69 14 14 0
SETD2 SETD2 Q9BYW2 Histone-lysine N-methyltransferase SETD2 chr3 Census, Compendium Yes 1 hippie 321 1945 209 209 2
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 Not Cancer Driver No 1 hippie 177 34 8 8 0
SNAP25 SNAP25 P60880 Synaptosomal-associated protein 25 chr20 Not Cancer Driver No 1 hippie 61 176 49 49 1
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SVIL SVIL O95425 Supervillin chr10 Not Cancer Driver No 1 intact, hippie 308 1423 192 192 0
SYCE1_ENST00000343131 SYCE1 Q8N0S2 Synaptonemal complex central element protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 70 251 50 50 0
TCP10L TCP10L Q8TDR4 T-complex protein 10A homolog 1 chr21 Not Cancer Driver No 2 intact, hippie, biogrid 32 213 32 32 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 Not Cancer Driver No 1 hippie 63 220 34 34 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 Not Cancer Driver No 1 hippie 33 361 20 20 0
TMA16 TMA16 Q96EY4 Translation machinery-associated protein 16 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 25 112 10 10 0
TOP3B_ENST00000357179 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 Not Cancer Driver No 1 hippie 102 151 17 17 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TSC22D1 TSC22D1 Q15714 TSC22 domain family protein 1 chr13 Not Cancer Driver No 1 intact, hippie 110 1023 98 98 0
TXLNA_ENST00000373610 TXLNA P40222 Alpha-taxilin chr1 Not Cancer Driver No 1 hippie, biogrid 68 481 59 59 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WASF3 WASF3 Q9UPY6 Wiskott-Aldrich syndrome protein family member 3 chr13 Not Cancer Driver No 1 intact, hippie, biogrid 108 386 84 84 0