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CDKN2C_ENST00000371761 ,CDKN2C ,P42773
  • Uniprot Accession= P42773
  • Ensembl Transcript= ENST00000371761.3
  • Uniprot Name= CDKN2C
  • Name= Cyclin-dependent kinase 4 inhibitor C
  • Chromosome= chr1
  • Driver status= Census, Compendium
  • Number of Interaction partner in intact: 38
  • Number of Interaction partner in biogrid: 37
  • Number of Interaction partner in hippie: 93
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACOX1_ENST00000301608 ACOX1 Q15067 Peroxisomal acyl-coenzyme A oxidase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 71 63 11 11 7
AHCYL1 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 4 intact, hippie 58 108 10 10 0
AK2 AK2 P54819 Adenylate kinase 2, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 23 76 12 12 2
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
ANGPTL4 ANGPTL4 Q9BY76 Angiopoietin-related protein 4 chr19 Not Cancer Driver No 1 intact, hippie 47 180 22 22 0
ANKRD44 ANKRD44 Q8N8A2 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B chr2 Not Cancer Driver No 3 intact, hippie, biogrid 135 130 13 13 0
APLP1 APLP1 P51693 Amyloid beta precursor like protein 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 146 455 98 98 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 intact, hippie 128 418 71 71 17
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 Census Yes 1 hippie 77 511 56 56 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 Census, Compendium Yes 1 hippie 469 225 39 39 41
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 Census, Compendium Yes 1 hippie 338 106 14 14 1
ATXN7L1 ATXN7L1 Q9ULK2 Ataxin-7-like protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 60 710 48 48 0
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 Not Cancer Driver No 2 intact, hippie, biogrid 14 26 0 0 39
BEX4_ENST00000372691 BEX4 Q9NWD9 Protein BEX4 chrX Not Cancer Driver No 1 hippie, biogrid 13 120 13 13 0
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 Not Cancer Driver No 1 hippie, biogrid 18 0 0 0 0
CASP6 CASP6 P55212 Caspase-6 chr4 Not Cancer Driver No 1 hippie 28 24 4 4 0
CCDC90B CCDC90B Q9GZT6 Coiled-coil domain-containing protein 90B, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 31 76 6 6 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 Census, Compendium Yes 2 intact, hippie, biogrid 55 31 25 25 0
CCND2 CCND2 P30279 G1/S-specific cyclin-D2 chr12 Census, Compendium Yes 1 hippie 39 29 7 7 5
CCND3 CCND3 P30281 G1/S-specific cyclin-D3 chr6 Census, Compendium Yes 3 intact, hippie, biogrid 29 46 8 8 0
CCNE1 CCNE1 P24864 G1/S-specific cyclin-E1 chr19 Census Yes 1 hippie 63 142 26 26 0
CDA CDA P32320 Cytidine deaminase chr1 Not Cancer Driver No 2 intact, hippie, biogrid 21 8 0 0 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 hippie, biogrid 52 214 31 31 0
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 Census, Compendium Yes 15 intact, hippie, biogrid 52 52 5 5 3
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 Census Yes 15 intact, hippie, biogrid 40 24 3 3 1
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 Census, Compendium Yes 2 hippie, biogrid 166 83 88 88 36
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 Not Cancer Driver No 2 hippie, biogrid 15 67 3 3 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 Not Cancer Driver No 1 hippie, biogrid 17 44 3 3 0
COL20A1 COL20A1 Q9P218 Collagen alpha-1(XX) chain chr20 Not Cancer Driver No 1 intact, hippie, biogrid 209 647 115 115 0
COPS6 COPS6 Q7L5N1 COP9 signalosome complex subunit 6 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 38 30 6 6 0
CRX_ENST00000539067 CRX O43186 Cone-rod homeobox protein chr19 Not Cancer Driver No 1 intact, hippie 90 207 63 63 6
CTDSP1 CTDSP1 Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 chr2 Not Cancer Driver No 1 hippie 34 46 2 2 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DRAP1 DRAP1 Q14919 Dr1-associated corepressor chr11 Not Cancer Driver No 1 hippie, biogrid 28 170 22 22 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 1 hippie 171 187 39 39 3
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 hippie 113 162 28 28 0
GAS2L1_ENST00000621062 GAS2L1 Q99501 GAS2-like protein 1 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 76 474 50 50 0
GDF9 GDF9 O60383 Growth/differentiation factor 9 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 72 53 15 15 0
GIP GIP P09681 Gastric inhibitory polypeptide chr17 Not Cancer Driver No 1 hippie, biogrid 35 68 16 16 0
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 Census Yes 1 hippie 56 263 34 34 0
GPSM3_ENST00000375043 GPSM3 Q9Y4H4 G-protein-signaling modulator 3 chr6 Not Cancer Driver No 1 hippie, biogrid 26 160 26 26 0
GREB1_ENST00000234142 GREB1 Q4ZG55 Protein GREB1 chr2 Not Cancer Driver No 1 hippie 313 371 67 67 0
GRM1_ENST00000282753 GRM1 Q13255 Metabotropic glutamate receptor 1 chr6 Not Cancer Driver No 1 hippie 346 339 91 91 3
HIP1 HIP1 O00291 Huntingtin-interacting protein 1 chr7 Census, Compendium Yes 1 intact, hippie 137 510 70 70 0
KRT31 KRT31 Q15323 Keratin, type I cuticular Ha1 chr17 Not Cancer Driver No 1 hippie 116 64 16 16 0
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 intact, hippie 43 55 7 7 1
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 1 hippie 178 687 116 116 0
LNX2 LNX2 Q8N448 Ligand of Numb protein X 2 chr13 Not Cancer Driver No 1 intact, hippie 85 277 35 35 0
LRIF1 LRIF1 Q5T3J3 Ligand-dependent nuclear receptor-interacting factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 116 520 74 74 0
LY96 LY96 Q9Y6Y9 Lymphocyte antigen 96 chr8 Not Cancer Driver No 1 hippie 37 0 0 0 0
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 Not Cancer Driver No 1 hippie 104 75 27 27 0
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 Not Cancer Driver No 1 hippie 40 85 10 10 0
MAPK10_ENST00000515650 MAPK10 P53779 Mitogen-activated protein kinase 10 chr4 Not Cancer Driver No 1 hippie 88 107 16 16 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie, biogrid 62 2 0 0 7
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 Not Cancer Driver No 1 hippie 64 94 9 9 0
MARS2 MARS2 Q96GW9 Methionine--tRNA ligase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 75 34 6 6 1
MTA3 MTA3 Q9BTC8 Metastasis-associated protein MTA3 chr2 Not Cancer Driver No 1 intact, hippie 48 169 18 18 0
MTMR14 MTMR14 Q8NCE2 Myotubularin-related protein 14 chr3 Not Cancer Driver No 1 hippie 58 150 8 8 2
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NAGK_ENST00000244204 NAGK Q9UJ70 N-acetyl-D-glucosamine kinase chr2 Not Cancer Driver No 1 hippie 46 5 1 1 0
NAT2 NAT2 P11245 Arylamine N-acetyltransferase 2 chr8 Not Cancer Driver No 1 intact, hippie 52 0 0 0 0
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 69 252 26 26 16
NIF3L1_ENST00000409357 NIF3L1 Q9GZT8 NIF3-like protein 1 chr2 Not Cancer Driver No 1 hippie 55 43 3 3 0
PBX4 PBX4 Q9BYU1 Pre-B-cell leukemia transcription factor 4 chr19 Not Cancer Driver No 1 intact, hippie 47 262 26 26 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 Census, Compendium Yes 1 hippie 290 173 45 45 2
PLEKHG4 PLEKHG4 Q58EX7 Puratrophin-1 chr16 Not Cancer Driver No 1 hippie 132 295 35 35 0
POU6F2 POU6F2 P78424 POU domain, class 6, transcription factor 2 chr7 Not Cancer Driver No 1 intact, hippie 165 571 144 144 1
PPM1J PPM1J Q5JR12 Protein phosphatase 1J chr1 Not Cancer Driver No 1 hippie, biogrid 51 206 16 16 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 1 intact, hippie 41 12 1 1 8
PROSER2 PROSER2 Q86WR7 Proline and serine-rich protein 2 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 30 423 29 29 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 intact, hippie 83 694 57 57 0
PYM1 PYM1 Q9BRP8 Partner of Y14 and mago chr12 Not Cancer Driver No 1 intact, hippie 22 204 22 22 0
QPCTL QPCTL Q9NXS2 Glutaminyl-peptide cyclotransferase-like protein chr19 Not Cancer Driver No 1 hippie, biogrid 42 22 1 1 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 1 hippie 89 169 38 38 22
RBM48 RBM48 Q5RL73 RNA-binding protein 48 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 65 176 39 39 0
REL REL Q04864 Proto-oncogene c-Rel chr2 Census Yes 3 intact, hippie 68 363 43 43 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 Not Cancer Driver No 1 intact, hippie 287 1355 164 164 0
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact, hippie 137 417 61 61 0
SCGB2A2 SCGB2A2 Q13296 Mammaglobin-A chr11 Not Cancer Driver No 1 intact, hippie 11 0 0 0 0
SLX1A_ENST00000345535 SLX1A Q9BQ83-2 Isoform 2 of Structure-specific endonuclease subunit SLX1 chr16 Not Cancer Driver No 2 hippie, biogrid 5 27 0 0 0
SNU13_ENST00000355257 SNU13 P55769 NHP2-like protein 1 chr22 Not Cancer Driver No 1 intact, hippie 17 2 0 0 0
SORBS3 SORBS3 O60504 Vinexin chr8 Not Cancer Driver No 1 hippie 62 577 56 56 0
SPX SPX Q9BT56 Spexin chr12 Not Cancer Driver No 1 hippie, biogrid 22 40 8 8 0
ST14 ST14 Q9Y5Y6 Suppressor of tumorigenicity 14 protein chr11 Not Cancer Driver No 1 intact, hippie 106 47 5 5 1
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 Census, Compendium Yes 1 hippie 75 135 14 14 9
TCF12_ENST00000267811 TCF12 Q99081 Transcription factor 12 chr15 Census Yes 3 intact, hippie 105 680 105 105 3
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 Compendium Yes 1 hippie 141 662 136 136 13
TLE1 TLE1 Q04724 Transducin-like enhancer protein 1 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 111 381 53 53 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 intact, hippie, biogrid 2891 282 1466 1466 83
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 Not Cancer Driver No 1 intact, hippie, biogrid 20 89 4 4 1