Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACLY_ENST00000590151 | ACLY | P53396 | ATP-citrate synthase | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 120 | 114 | 12 | 12 | 0 |
ACTA1 | ACTA1 | P68133 | Actin, alpha skeletal muscle | chr1 | Not Cancer Driver | No | 1 | hippie | 70 | 48 | 14 | 14 | 84 |
ACTBL2 | ACTBL2 | Q562R1 | Beta-actin-like protein 2 | chr5 | Not Cancer Driver | No | 1 | hippie | 73 | 29 | 5 | 5 | 0 |
ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 112 | 43 | 5 | 5 | 5 |
ACTG1_ENST00000575087 | ACTG1 | P63261 | Actin, cytoplasmic 2 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 73 | 42 | 10 | 10 | 16 |
ACTN4 | ACTN4 | O43707 | Alpha-actinin-4 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 131 | 244 | 42 | 42 | 8 |
ACTR3B | ACTR3B | Q9P1U1 | Actin-related protein 3B | chr7 | Not Cancer Driver | No | 1 | hippie | 55 | 5 | 0 | 0 | 0 |
AHNAK | AHNAK | Q09666 | Neuroblast differentiation-associated protein AHNAK | chr11 | Not Cancer Driver | No | 1 | hippie | 805 | 5777 | 794 | 794 | 0 |
AK2 | AK2 | P54819 | Adenylate kinase 2, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 76 | 12 | 12 | 2 |
AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | Census, Compendium | Yes | 1 | hippie | 108 | 158 | 24 | 24 | 4 |
ALDOB | ALDOB | P05062 | Fructose-bisphosphate aldolase B | chr9 | Not Cancer Driver | No | 1 | hippie | 91 | 34 | 11 | 11 | 16 |
ANAPC15_ENST00000538393 | ANAPC15 | P60006 | Anaphase-promoting complex subunit 15 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 15 | 117 | 14 | 14 | 0 |
ANGPTL4 | ANGPTL4 | Q9BY76 | Angiopoietin-related protein 4 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 47 | 180 | 22 | 22 | 0 |
ANKRA2 | ANKRA2 | Q9H9E1 | Ankyrin repeat family A protein 2 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 31 | 97 | 11 | 11 | 0 |
ANKRD12 | ANKRD12 | Q6UB98 | Ankyrin repeat domain-containing protein 12 | chr18 | Not Cancer Driver | No | 1 | hippie | 232 | 1746 | 205 | 205 | 0 |
AR | AR | P10275 | Androgen receptor | chrX | Census, Compendium | Yes | 1 | hippie | 196 | 443 | 88 | 88 | 169 |
ARFIP2_ENST00000254584 | ARFIP2 | P53365 | Arfaptin-2 | chr11 | Not Cancer Driver | No | 1 | hippie | 37 | 144 | 15 | 15 | 0 |
ARHGAP25 | ARHGAP25 | P42331 | Rho GTPase-activating protein 25 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 120 | 339 | 62 | 62 | 0 |
ARHGEF6 | ARHGEF6 | Q15052 | Rho guanine nucleotide exchange factor 6 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 158 | 223 | 45 | 45 | 0 |
ARNT | ARNT | P27540 | Aryl hydrocarbon receptor nuclear translocator | chr1 | Census | Yes | 1 | hippie | 77 | 511 | 56 | 56 | 0 |
ASPRV1 | ASPRV1 | Q53RT3 | Retroviral-like aspartic protease 1 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 66 | 85 | 18 | 18 | 3 |
ATG5_ENST00000343245 | ATG5 | Q9H1Y0 | Autophagy protein 5 | chr6 | Not Cancer Driver | No | 1 | hippie | 40 | 25 | 6 | 6 | 1 |
ATR | ATR | Q13535 | Serine/threonine-protein kinase ATR | chr3 | Census, Compendium | Yes | 1 | hippie | 338 | 106 | 14 | 14 | 1 |
AURKA_ENST00000395915 | AURKA | O14965 | Aurora kinase A | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 178 | 21 | 21 | 0 |
AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | Not Cancer Driver | No | 2 | hippie | 51 | 63 | 8 | 8 | 0 |
AZIN1 | AZIN1 | O14977 | Antizyme inhibitor 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 39 | 10 | 2 | 2 | 0 |
BAAT_ENST00000395051 | BAAT | Q14032 | Bile acid-CoA:amino acid N-acyltransferase | chr9 | Not Cancer Driver | No | 1 | hippie | 88 | 10 | 4 | 4 | 1 |
BACH1_ENST00000286800 | BACH1 | O14867 | Transcription regulator protein BACH1 | chr21 | Not Cancer Driver | No | 1 | hippie | 105 | 328 | 39 | 39 | 0 |
BAG6 | BAG6 | P46379 | Large proline-rich protein BAG6 | chr6 | Not Cancer Driver | No | 1 | hippie | 98 | 861 | 79 | 79 | 0 |
BAP1 | BAP1 | Q92560 | Ubiquitin carboxyl-terminal hydrolase BAP1 | chr3 | Census, Compendium | Yes | 1 | hippie | 141 | 418 | 59 | 59 | 0 |
BCL2L1 | BCL2L1 | Q07817 | Bcl-2-like protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 29 | 55 | 3 | 3 | 0 |
BECN1_ENST00000590099 | BECN1 | Q14457 | Beclin-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 45 | 190 | 19 | 19 | 0 |
BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 224 | 1458 | 174 | 174 | 35 |
BRK1 | BRK1 | Q8WUW1 | Protein BRICK1 | chr3 | Not Cancer Driver | No | 1 | hippie | 7 | 14 | 1 | 1 | 0 |
BRPF3 | BRPF3 | Q9ULD4 | Bromodomain and PHD finger-containing protein 3 | chr6 | Not Cancer Driver | No | 1 | hippie | 143 | 633 | 74 | 74 | 0 |
C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | Not Cancer Driver | No | 2 | hippie | 14 | 103 | 6 | 6 | 2 |
C9orf3 | AOPEP | Q8N6M6 | Aminopeptidase O | chr9 | Not Cancer Driver | No | 1 | hippie | 87 | 107 | 13 | 13 | 0 |
CANX_ENST00000504734 | CANX | P27824 | Calnexin | chr5 | Not Cancer Driver | No | 1 | hippie | 65 | 334 | 38 | 38 | 0 |
CARF | CARF | Q8N187 | Calcium-responsive transcription factor | chr2 | Not Cancer Driver | No | 1 | hippie | 93 | 503 | 63 | 63 | 0 |
CASC3 | CASC3 | O15234 | Protein CASC3 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 84 | 700 | 83 | 83 | 0 |
CCDC180 | CCDC180 | Q9P1Z9 | Coiled-coil domain-containing protein 180 | chr9 | Not Cancer Driver | No | 1 | hippie | 212 | 588 | 96 | 96 | 0 |
CCDC183 | CCDC183 | Q5T5S1 | Coiled-coil domain-containing protein 183 | chr9 | Not Cancer Driver | No | 1 | hippie | 61 | 206 | 25 | 25 | 0 |
CCND1 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | Census, Compendium | Yes | 3 | intact, hippie | 55 | 31 | 25 | 25 | 0 |
CCND2 | CCND2 | P30279 | G1/S-specific cyclin-D2 | chr12 | Census, Compendium | Yes | 1 | hippie | 39 | 29 | 7 | 7 | 5 |
CCNDBP1 | CCNDBP1 | O95273 | Cyclin-D1-binding protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 35 | 63 | 5 | 5 | 0 |
CCNE1 | CCNE1 | P24864 | G1/S-specific cyclin-E1 | chr19 | Census | Yes | 1 | hippie | 63 | 142 | 26 | 26 | 0 |
CCNF | CCNF | P41002 | Cyclin-F | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 221 | 23 | 23 | 3 |
CCNG1_ENST00000393929 | CCNG1 | P51959 | Cyclin-G1 | chr5 | Not Cancer Driver | No | 1 | hippie | 25 | 0 | 0 | 0 | 0 |
CD44 | CD44 | P16070 | CD44 antigen | chr11 | Not Cancer Driver | No | 1 | hippie | 75 | 542 | 60 | 60 | 0 |
CDC14B | CDC14B | O60729 | Dual specificity protein phosphatase CDC14B | chr9 | Not Cancer Driver | No | 1 | hippie | 61 | 138 | 15 | 15 | 0 |
CDC37 | CDC37 | Q16543 | Hsp90 co-chaperone Cdc37 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 214 | 31 | 31 | 0 |
CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
CDC45_ENST00000407835 | CDC45 | O75419 | Cell division control protein 45 homolog | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 73 | 66 | 16 | 16 | 5 |
CDC5L | CDC5L | Q99459 | Cell division cycle 5-like protein | chr6 | Not Cancer Driver | No | 1 | hippie | 100 | 618 | 77 | 77 | 0 |
CDC6 | CDC6 | Q99741 | Cell division control protein 6 homolog | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 57 | 170 | 15 | 15 | 1 |
CDC7 | CDC7 | O00311 | Cell division cycle 7-related protein kinase | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 72 | 185 | 24 | 24 | 0 |
CDK11A | CDK11A | Q9UQ88 | Cyclin-dependent kinase 11A | chr1 | Not Cancer Driver | No | 1 | hippie | 66 | 485 | 44 | 44 | 0 |
CDK4 | CDK4 | P11802 | Cyclin-dependent kinase 4 | chr12 | Census, Compendium | Yes | 15 | intact, hippie, biogrid | 52 | 52 | 5 | 5 | 3 |
CDK5RAP3_ENST00000338399 | CDK5RAP3 | Q96JB5 | CDK5 regulatory subunit-associated protein 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 50 | 99 | 20 | 20 | 0 |
CDK6 | CDK6 | Q00534 | Cyclin-dependent kinase 6 | chr7 | Census | Yes | 10 | intact, hippie, biogrid | 40 | 24 | 3 | 3 | 1 |
CDKN1C | CDKN1C | P49918 | Cyclin-dependent kinase inhibitor 1C | chr11 | Not Cancer Driver | No | 1 | hippie | 2 | 256 | 1 | 1 | 7 |
CDKN2AIP | CDKN2AIP | Q9NXV6 | CDKN2A-interacting protein | chr4 | Not Cancer Driver | No | 2 | hippie | 53 | 352 | 38 | 38 | 0 |
CDKN2A_ENST00000304494 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | Census, Compendium | Yes | 1 | hippie | 166 | 83 | 88 | 88 | 36 |
CDKN2B | CDKN2B | P42772 | Cyclin-dependent kinase 4 inhibitor B | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 15 | 67 | 3 | 3 | 0 |
CDKN2C_ENST00000371761 | CDKN2C | P42773 | Cyclin-dependent kinase 4 inhibitor C | chr1 | Census, Compendium | Yes | 2 | hippie, biogrid | 23 | 49 | 6 | 6 | 0 |
CDKN2D_ENST00000335766 | CDKN2D | P55273 | Cyclin-dependent kinase 4 inhibitor D | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 44 | 3 | 3 | 0 |
CENPA | CENPA | P49450 | Histone H3-like centromeric protein A | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 15 | 50 | 4 | 4 | 0 |
CFAP97 | CFAP97 | Q9P2B7 | Cilia- and flagella-associated protein 97 | chr4 | Not Cancer Driver | No | 1 | hippie | 63 | 530 | 63 | 63 | 0 |
CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
CLK2 | CLK2 | P49760 | Dual specificity protein kinase CLK2 | chr1 | Not Cancer Driver | No | 1 | hippie | 104 | 151 | 37 | 37 | 0 |
CLUAP1_ENST00000576634 | CLUAP1 | Q96AJ1 | Clusterin-associated protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 48 | 203 | 22 | 22 | 0 |
COMMD1 | COMMD1 | Q8N668 | COMM domain-containing protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 21 | 17 | 0 | 0 | 0 |
COPS5 | COPS5 | Q92905 | COP9 signalosome complex subunit 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 36 | 32 | 7 | 7 | 0 |
COPS6 | COPS6 | Q7L5N1 | COP9 signalosome complex subunit 6 | chr7 | Not Cancer Driver | No | 1 | hippie | 38 | 30 | 6 | 6 | 0 |
CRELD2_ENST00000328268 | CRELD2 | Q6UXH1 | Protein disulfide isomerase CRELD2 | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 39 | 33 | 6 | 6 | 0 |
CSTF2_ENST00000372972 | CSTF2 | P33240 | Cleavage stimulation factor subunit 2 | chrX | Not Cancer Driver | No | 1 | hippie | 85 | 484 | 72 | 72 | 0 |
CTBP2_ENST00000494626 | CTBP2 | P56545 | C-terminal-binding protein 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 48 | 94 | 4 | 4 | 0 |
CTSV | CTSV | O60911 | Cathepsin L2 | chr9 | Not Cancer Driver | No | 1 | hippie | 55 | 7 | 1 | 1 | 0 |
CUL1_ENST00000602748 | CUL1 | Q13616 | Cullin-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 151 | 65 | 9 | 9 | 0 |
CUL2_ENST00000374748 | CUL2 | Q13617 | Cullin-2 | chr10 | Not Cancer Driver | No | 1 | hippie | 87 | 66 | 3 | 3 | 0 |
CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | Census, Compendium | Yes | 1 | hippie | 123 | 167 | 23 | 23 | 3 |
CYLC2 | CYLC2 | Q14093 | Cylicin-2 | chr9 | Not Cancer Driver | No | 1 | hippie | 167 | 318 | 149 | 149 | 0 |
DAXX_ENST00000266000 | DAXX | Q9UER7 | Death domain-associated protein 6 | chr6 | Census, Compendium | Yes | 1 | hippie | 106 | 549 | 81 | 81 | 0 |
DEAF1 | DEAF1 | O75398 | Deformed epidermal autoregulatory factor 1 homolog | chr11 | Not Cancer Driver | No | 1 | hippie | 75 | 370 | 51 | 51 | 4 |
DGCR8 | DGCR8 | Q8WYQ5 | Microprocessor complex subunit DGCR8 | chr22 | Census, Compendium | Yes | 1 | hippie | 102 | 466 | 57 | 57 | 0 |
DYRK1B_ENST00000323039 | DYRK1B | Q9Y463 | Dual specificity tyrosine-phosphorylation-regulated kinase 1B | chr19 | Not Cancer Driver | No | 1 | hippie | 77 | 319 | 38 | 38 | 2 |
E2F1 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | Not Cancer Driver | No | 1 | hippie | 49 | 272 | 23 | 23 | 0 |
E4F1 | E4F1 | Q66K89 | Transcription factor E4F1 | chr16 | Not Cancer Driver | No | 1 | hippie | 84 | 462 | 46 | 46 | 0 |
ECT2 | ECT2 | Q9H8V3 | Protein ECT2 | chr3 | Not Cancer Driver | No | 1 | hippie | 104 | 284 | 33 | 33 | 0 |
EEF2 | EEF2 | P13639 | Elongation factor 2 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 111 | 78 | 14 | 14 | 1 |
EFHC2 | EFHC2 | Q5JST6 | EF-hand domain-containing family member C2 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 113 | 50 | 10 | 10 | 0 |
EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
EGR1 | EGR1 | P18146 | Early growth response protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 78 | 501 | 72 | 72 | 0 |
EIF1B | EIF1B | O60739 | Eukaryotic translation initiation factor 1b | chr3 | Not Cancer Driver | No | 1 | hippie | 12 | 6 | 0 | 0 | 0 |
EIF3A | EIF3A | Q14152 | Eukaryotic translation initiation factor 3 subunit A | chr10 | Not Cancer Driver | No | 1 | hippie | 181 | 835 | 130 | 130 | 0 |
ELOB_ENST00000409906 | ELOB | Q15370 | Elongin-B | chr16 | Not Cancer Driver | No | 1 | hippie | 13 | 69 | 10 | 10 | 0 |
EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 334 | 1790 | 196 | 196 | 1 |
EPB41_ENST00000373798 | EPB41 | P11171 | Protein 4.1 | chr1 | Not Cancer Driver | No | 1 | hippie | 101 | 557 | 69 | 69 | 0 |
EPHA2 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | Compendium | Yes | 1 | hippie | 171 | 187 | 39 | 39 | 3 |
EPHA3 | EPHA3 | P29320 | Ephrin type-A receptor 3 | chr3 | Census, Compendium | Yes | 1 | intact, hippie | 346 | 74 | 28 | 28 | 0 |
ERBB3 | ERBB3 | P21860 | Receptor tyrosine-protein kinase erbB-3 | chr12 | Census, Compendium | Yes | 1 | hippie | 298 | 396 | 70 | 70 | 3 |
ERGIC1 | ERGIC1 | Q969X5 | Endoplasmic reticulum-Golgi intermediate compartment protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 26 | 2 | 2 | 0 |
EXOC2 | EXOC2 | Q96KP1 | Exocyst complex component 2 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 105 | 134 | 18 | 18 | 0 |
FAM160A1_ENST00000505231 | FHIP1A | Q05DH4 | FHF complex subunit HOOK interacting protein 1A | chr4 | Not Cancer Driver | No | 1 | intact | 47 | 341 | 8 | 8 | 0 |
FBL | FBL | P22087 | rRNA 2'-O-methyltransferase fibrillarin | chr19 | Not Cancer Driver | No | 1 | hippie | 46 | 145 | 22 | 22 | 0 |
FGFR4 | FGFR4 | P22455 | Fibroblast growth factor receptor 4 | chr5 | Census, Compendium | Yes | 1 | hippie | 113 | 162 | 28 | 28 | 0 |
FKBP2_ENST00000449942 | FKBP2 | P26885 | Peptidyl-prolyl cis-trans isomerase FKBP2 | chr11 | Not Cancer Driver | No | 1 | hippie | 15 | 20 | 1 | 1 | 0 |
FN1 | FN1 | P02751 | Fibronectin | chr2 | Compendium | Yes | 1 | intact, hippie | 394 | 1243 | 185 | 185 | 8 |
FRAT2 | FRAT2 | O75474 | GSK-3-binding protein FRAT2 | chr10 | Not Cancer Driver | No | 1 | hippie | 1 | 195 | 1 | 1 | 0 |
FTSJ1 | FTSJ1 | Q9UET6 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase | chrX | Not Cancer Driver | No | 1 | intact, hippie | 44 | 89 | 14 | 14 | 0 |
FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 74 | 184 | 30 | 30 | 0 |
GALNT12 | GALNT12 | Q8IXK2 | Polypeptide N-acetylgalactosaminyltransferase 12 | chr9 | Not Cancer Driver | No | 1 | hippie | 68 | 64 | 2 | 2 | 8 |
GAPDH | GAPDH | P04406 | Glyceraldehyde-3-phosphate dehydrogenase | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 39 | 24 | 3 | 3 | 0 |
GGA1 | GGA1 | Q9UJY5 | ADP-ribosylation factor-binding protein GGA1 | chr22 | Not Cancer Driver | No | 1 | hippie | 75 | 385 | 33 | 33 | 0 |
GGA3 | GGA3 | Q9NZ52 | ADP-ribosylation factor-binding protein GGA3 | chr17 | Not Cancer Driver | No | 1 | hippie | 73 | 419 | 41 | 41 | 0 |
GLIS1 | GLIS1 | Q8NBF1 | Zinc finger protein GLIS1 | chr1 | Not Cancer Driver | No | 1 | hippie | 106 | 404 | 66 | 66 | 0 |
GLIS2 | GLIS2 | Q9BZE0 | Zinc finger protein GLIS2 | chr16 | Not Cancer Driver | No | 1 | hippie | 42 | 300 | 25 | 25 | 0 |
GMNN_ENST00000620958 | GMNN | O75496 | Geminin | chr6 | Not Cancer Driver | No | 2 | intact, hippie | 24 | 206 | 24 | 24 | 1 |
GNL3 | GNL3 | Q9BVP2 | Guanine nucleotide-binding protein-like 3 | chr3 | Not Cancer Driver | No | 1 | hippie | 56 | 257 | 21 | 21 | 0 |
GSPT1_ENST00000563468 | GSPT1 | P15170 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A | chr16 | Not Cancer Driver | No | 1 | hippie | 42 | 149 | 13 | 13 | 0 |
HAUS1 | HAUS1 | Q96CS2 | HAUS augmin-like complex subunit 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 47 | 60 | 11 | 11 | 0 |
HDAC1 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 47 | 135 | 10 | 10 | 0 |
HGF_ENST00000644543 | HGF | P14210 | Hepatocyte growth factor | chr7 | Compendium | Yes | 1 | hippie | 233 | 43 | 16 | 16 | 0 |
HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | Census | Yes | 1 | hippie | 118 | 435 | 51 | 51 | 0 |
HIPK4 | HIPK4 | Q8NE63 | Homeodomain-interacting protein kinase 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 258 | 23 | 23 | 0 |
HLA-B | HLA-B | P01889 | HLA class I histocompatibility antigen, B alpha chain | chr6 | Compendium | Yes | 1 | hippie | 78 | 169 | 34 | 34 | 0 |
HLA-DOB | HLA-DOB | P13765 | HLA class II histocompatibility antigen, DO beta chain | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 34 | 9 | 2 | 2 | 0 |
HNRNPA2B1 | HNRNPA2B1 | P22626 | Heterogeneous nuclear ribonucleoproteins A2/B1 | chr7 | Census, Compendium | Yes | 1 | intact, hippie | 68 | 255 | 41 | 41 | 0 |
HNRNPC_ENST00000420743 | HNRNPC | P07910 | Heterogeneous nuclear ribonucleoproteins C1/C2 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 42 | 227 | 35 | 35 | 0 |
HNRNPH1 | HNRNPH1 | P31943 | Heterogeneous nuclear ribonucleoprotein H | chr5 | Not Cancer Driver | No | 1 | hippie | 51 | 169 | 29 | 29 | 0 |
HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 77 | 504 | 45 | 45 | 0 |
HRAS | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | hippie | 107 | 16 | 4 | 4 | 18 |
HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | Census, Compendium | Yes | 1 | intact, hippie | 106 | 257 | 37 | 37 | 0 |
HSP90AB1 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | Census, Compendium | Yes | 2 | intact, hippie | 100 | 254 | 43 | 43 | 0 |
HSPA4 | HSPA4 | P34932 | Heat shock 70 kDa protein 4 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 80 | 351 | 24 | 24 | 0 |
HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 149 | 251 | 52 | 52 | 0 |
HSPA9 | HSPA9 | P38646 | Stress-70 protein, mitochondrial | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 67 | 283 | 26 | 26 | 2 |
HUWE1_ENST00000262854 | HUWE1 | Q7Z6Z7 | E3 ubiquitin-protein ligase HUWE1 | chrX | Not Cancer Driver | No | 1 | hippie | 669 | 2091 | 329 | 329 | 21 |
IKBKB | IKBKB | O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | chr8 | Census, Compendium | Yes | 1 | hippie | 106 | 211 | 31 | 31 | 1 |
IKBKE | IKBKE | Q14164 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 108 | 76 | 13 | 13 | 0 |
IMPDH1_ENST00000626419 | IMPDH1 | P20839 | Inosine-5'-monophosphate dehydrogenase 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 13 | 1 | 1 | 7 |
ING1 | ING1 | Q9UK53 | Inhibitor of growth protein 1 | chr13 | Compendium | Yes | 1 | hippie | 69 | 209 | 33 | 33 | 3 |
ING4 | ING4 | Q9UNL4 | Inhibitor of growth protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie | 31 | 108 | 15 | 15 | 0 |
IQGAP1 | IQGAP1 | P46940 | Ras GTPase-activating-like protein IQGAP1 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 183 | 351 | 35 | 35 | 0 |
ISOC2_ENST00000425675 | ISOC2 | Q96AB3 | Isochorismatase domain-containing protein 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 24 | 8 | 0 | 0 | 0 |
KAT2B | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | Not Cancer Driver | No | 1 | hippie | 107 | 266 | 27 | 27 | 0 |
KAT5_ENST00000377046 | KAT5 | Q92993 | Histone acetyltransferase KAT5 | chr11 | Not Cancer Driver | No | 1 | hippie | 65 | 173 | 21 | 21 | 3 |
KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 774 | 102 | 102 | 2 |
KSR1_ENST00000644974 | KSR1 | Q8IVT5 | Kinase suppressor of Ras 1 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 114 | 404 | 58 | 58 | 0 |
KSR2_ENST00000339824 | KSR2 | Q6VAB6 | Kinase suppressor of Ras 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 231 | 434 | 120 | 120 | 0 |
LAMTOR3 | LAMTOR3 | Q9UHA4 | Ragulator complex protein LAMTOR3 | chr4 | Not Cancer Driver | No | 1 | hippie | 12 | 0 | 0 | 0 | 0 |
LATS2 | LATS2 | Q9NRM7 | Serine/threonine-protein kinase LATS2 | chr13 | Census, Compendium | Yes | 1 | hippie | 178 | 687 | 116 | 116 | 0 |
LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
LMNA | LMNA | P02545 | Prelamin-A/C | chr1 | Census | Yes | 1 | hippie | 68 | 544 | 49 | 49 | 131 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
LSM8 | LSM8 | O95777 | U6 snRNA-associated Sm-like protein LSm8 | chr7 | Not Cancer Driver | No | 1 | hippie | 14 | 3 | 1 | 1 | 0 |
MAF1_ENST00000532522 | MAF1 | Q9H063 | Repressor of RNA polymerase III transcription MAF1 homolog | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 22 | 74 | 4 | 4 | 0 |
MAFB | MAFB | Q9Y5Q3 | Transcription factor MafB | chr20 | Census | Yes | 1 | hippie | 35 | 301 | 34 | 34 | 10 |
MAP2K1 | MAP2K1 | Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | chr15 | Census, Compendium | Yes | 1 | hippie | 94 | 96 | 24 | 24 | 6 |
MAP2K5 | MAP2K5 | Q13163 | Dual specificity mitogen-activated protein kinase kinase 5 | chr15 | Not Cancer Driver | No | 1 | hippie | 40 | 85 | 10 | 10 | 0 |
MAP3K5 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | Not Cancer Driver | No | 1 | hippie | 197 | 242 | 29 | 29 | 0 |
MAPK10_ENST00000515650 | MAPK10 | P53779 | Mitogen-activated protein kinase 10 | chr4 | Not Cancer Driver | No | 1 | hippie | 88 | 107 | 16 | 16 | 0 |
MAPK14_ENST00000229794 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | Not Cancer Driver | No | 1 | hippie | 39 | 25 | 1 | 1 | 0 |
MAPK1_ENST00000398822 | MAPK1 | P28482 | Mitogen-activated protein kinase 1 | chr22 | Census, Compendium | Yes | 1 | hippie, biogrid | 62 | 2 | 0 | 0 | 7 |
MAPK3 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | Not Cancer Driver | No | 1 | hippie | 38 | 49 | 5 | 5 | 0 |
MAPK6 | MAPK6 | Q16659 | Mitogen-activated protein kinase 6 | chr15 | Not Cancer Driver | No | 1 | hippie | 79 | 165 | 20 | 20 | 0 |
MAPK8_ENST00000374189 | MAPK8 | P45983 | Mitogen-activated protein kinase 8 | chr10 | Not Cancer Driver | No | 1 | hippie | 64 | 94 | 9 | 9 | 0 |
MAPKAPK3 | MAPKAPK3 | Q16644 | MAP kinase-activated protein kinase 3 | chr3 | Not Cancer Driver | No | 1 | hippie | 35 | 117 | 12 | 12 | 1 |
MCC_ENST00000302475 | MCC | P23508 | Colorectal mutant cancer protein | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 136 | 589 | 92 | 92 | 0 |
MCM10 | MCM10 | Q7L590 | Protein MCM10 homolog | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 152 | 535 | 102 | 102 | 1 |
MCM2 | MCM2 | P49736 | DNA replication licensing factor MCM2 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 104 | 275 | 38 | 38 | 1 |
MCM5 | MCM5 | P33992 | DNA replication licensing factor MCM5 | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 88 | 109 | 20 | 20 | 1 |
MCM6 | MCM6 | Q14566 | DNA replication licensing factor MCM6 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 101 | 122 | 13 | 13 | 0 |
MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 2 | hippie | 56 | 297 | 37 | 37 | 0 |
MDM4 | MDM4 | O15151 | Protein Mdm4 | chr1 | Census, Compendium | Yes | 1 | hippie | 57 | 202 | 26 | 26 | 1 |
METTL14 | METTL14 | Q9HCE5 | N6-adenosine-methyltransferase non-catalytic subunit | chr4 | Not Cancer Driver | No | 1 | hippie | 60 | 224 | 26 | 26 | 0 |
METTL3 | METTL3 | Q86U44 | N6-adenosine-methyltransferase catalytic subunit | chr14 | Not Cancer Driver | No | 1 | hippie | 74 | 274 | 29 | 29 | 0 |
MIS12 | MIS12 | Q9H081 | Protein MIS12 homolog | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 14 | 15 | 2 | 2 | 0 |
MMRN1 | MMRN1 | Q13201 | Multimerin-1 | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 241 | 373 | 75 | 75 | 0 |
MOV10_ENST00000357443 | MOV10 | Q9HCE1 | Helicase MOV-10 | chr1 | Not Cancer Driver | No | 1 | hippie | 110 | 101 | 8 | 8 | 0 |
MTA1 | MTA1 | Q13330 | Metastasis-associated protein MTA1 | chr14 | Not Cancer Driver | No | 1 | hippie | 92 | 327 | 42 | 42 | 0 |
MTR | MTR | Q99707 | Methionine synthase | chr1 | Not Cancer Driver | No | 1 | hippie | 151 | 104 | 17 | 17 | 2 |
MYCN | MYCN | P04198 | N-myc proto-oncogene protein | chr2 | Census, Compendium | Yes | 1 | hippie | 71 | 415 | 64 | 64 | 3 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
MYL12A_ENST00000217652 | MYL12A | P19105 | Myosin regulatory light chain 12A | chr18 | Not Cancer Driver | No | 1 | intact, hippie | 19 | 70 | 13 | 13 | 0 |
MYO1C | MYO1C | O00159 | Unconventional myosin-Ic | chr17 | Not Cancer Driver | No | 1 | hippie | 110 | 66 | 11 | 11 | 0 |
NAT2 | NAT2 | P11245 | Arylamine N-acetyltransferase 2 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 52 | 0 | 0 | 0 | 0 |
NBR1 | NBR1 | Q14596 | Next to BRCA1 gene 1 protein | chr17 | Not Cancer Driver | No | 1 | hippie | 101 | 560 | 51 | 51 | 0 |
NCKAP1_ENST00000361354 | NCKAP1 | Q9Y2A7 | Nck-associated protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 129 | 44 | 3 | 3 | 0 |
NCL | NCL | P19338 | Nucleolin | chr2 | Not Cancer Driver | No | 1 | hippie | 85 | 569 | 68 | 68 | 0 |
NMI | NMI | Q13287 | N-myc-interactor | chr2 | Not Cancer Driver | No | 1 | hippie | 34 | 104 | 12 | 12 | 0 |
NOP53 | NOP53 | Q9NZM5 | Ribosome biogenesis protein NOP53 | chr19 | Not Cancer Driver | No | 1 | hippie | 59 | 391 | 41 | 41 | 0 |
NPM1 | NPM1 | P06748 | Nucleophosmin | chr5 | Census, Compendium | Yes | 2 | hippie | 29 | 249 | 22 | 22 | 0 |
NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
NSD3 | NSD3 | Q9BZ95 | Histone-lysine N-methyltransferase NSD3 | chr8 | Census | Yes | 1 | intact, hippie | 164 | 679 | 98 | 98 | 0 |
NXF1_ENST00000294172 | NXF1 | Q9UBU9 | Nuclear RNA export factor 1 | chr11 | Compendium | Yes | 1 | hippie | 100 | 163 | 32 | 32 | 0 |
OPTN_ENST00000263036 | OPTN | Q96CV9 | Optineurin | chr10 | Not Cancer Driver | No | 1 | hippie | 58 | 470 | 51 | 51 | 6 |
ORC4_ENST00000392857 | ORC4 | O43929 | Origin recognition complex subunit 4 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 52 | 14 | 2 | 2 | 1 |
ORC5 | ORC5 | O43913 | Origin recognition complex subunit 5 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 43 | 16 | 2 | 2 | 0 |
OTUB1_ENST00000428192 | OTUB1 | Q96FW1 | Ubiquitin thioesterase OTUB1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 31 | 33 | 2 | 2 | 0 |
PA2G4 | PA2G4 | Q9UQ80 | Proliferation-associated protein 2G4 | chr12 | Not Cancer Driver | No | 1 | hippie | 45 | 128 | 18 | 18 | 0 |
PANX1 | PANX1 | Q96RD7 | Pannexin-1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 45 | 7 | 7 | 2 |
PCLAF | PCLAF | Q15004 | PCNA-associated factor | chr15 | Not Cancer Driver | No | 1 | hippie | 20 | 111 | 20 | 20 | 0 |
PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 22 | 3 | 3 | 1 |
PDCD6 | PDCD6 | O75340 | Programmed cell death protein 6 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 21 | 24 | 1 | 1 | 0 |
PDGFRA | PDGFRA | P16234 | Platelet-derived growth factor receptor alpha | chr4 | Census, Compendium | Yes | 1 | hippie | 290 | 173 | 45 | 45 | 2 |
PEX19 | PEX19 | P40855 | Peroxisomal biogenesis factor 19 | chr1 | Not Cancer Driver | No | 1 | hippie | 41 | 266 | 38 | 38 | 0 |
PEX3 | PEX3 | P56589 | Peroxisomal biogenesis factor 3 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 24 | 0 | 0 | 2 |
PIAS2 | PIAS2 | O75928 | E3 SUMO-protein ligase PIAS2 | chr18 | Not Cancer Driver | No | 1 | hippie | 78 | 209 | 28 | 28 | 0 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
PLEKHA8 | PLEKHA8 | Q96JA3 | Pleckstrin homology domain-containing family A member 8 | chr7 | Not Cancer Driver | No | 1 | hippie | 57 | 128 | 22 | 22 | 0 |
PML | PML | P29590 | Protein PML | chr15 | Census, Compendium | Yes | 2 | hippie | 112 | 312 | 34 | 34 | 0 |
PPP1CB_ENST00000358506 | PPP1CB | P62140 | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | chr2 | Not Cancer Driver | No | 1 | hippie | 47 | 25 | 5 | 5 | 5 |
PPP1CC_ENST00000335007 | PPP1CC | P36873 | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | chr12 | Not Cancer Driver | No | 1 | hippie | 26 | 23 | 4 | 4 | 0 |
PPP1R9B | PPP1R9B | Q96SB3 | Neurabin-2 | chr17 | Not Cancer Driver | No | 1 | hippie | 47 | 695 | 35 | 35 | 0 |
PRAME_ENST00000402697 | PRAME | P78395 | Melanoma antigen preferentially expressed in tumors | chr22 | Not Cancer Driver | No | 1 | hippie | 95 | 10 | 1 | 1 | 0 |
PRC1 | PRC1 | O43663 | Protein regulator of cytokinesis 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 63 | 235 | 26 | 26 | 0 |
PRKCA | PRKCA | P17252 | Protein kinase C alpha type | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 94 | 154 | 22 | 22 | 0 |
PSEN1 | PSEN1 | P49768 | Presenilin-1 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 61 | 134 | 21 | 21 | 96 |
PSMC3_ENST00000298852 | PSMC3 | P17980 | 26S proteasome regulatory subunit 6A | chr11 | Not Cancer Driver | No | 1 | hippie | 55 | 131 | 10 | 10 | 0 |
PSME3_ENST00000590720 | PSME3 | P61289 | Proteasome activator complex subunit 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 20 | 25 | 5 | 5 | 0 |
PTP4A3_ENST00000521578 | PTP4A3 | O75365 | Protein tyrosine phosphatase type IVA 3 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 3 | 0 | 0 | 0 |
RAB5A | RAB5A | P20339 | Ras-related protein Rab-5A | chr3 | Not Cancer Driver | No | 1 | hippie | 32 | 65 | 15 | 15 | 0 |
RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 2 |
RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 4 |
RAF1 | RAF1 | P04049 | RAF proto-oncogene serine/threonine-protein kinase | chr3 | Census, Compendium | Yes | 1 | hippie | 89 | 169 | 38 | 38 | 22 |
RAN_ENST00000392369 | RAN | P62826 | GTP-binding nuclear protein Ran | chr12 | Not Cancer Driver | No | 1 | hippie | 20 | 14 | 1 | 1 | 0 |
RASA1 | RASA1 | P20936 | Ras GTPase-activating protein 1 | chr5 | Compendium | Yes | 1 | hippie | 154 | 181 | 25 | 25 | 3 |
RASSF1 | RASSF1 | Q9NS23 | Ras association domain-containing protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 36 | 79 | 3 | 3 | 0 |
RBM26_ENST00000438737 | RBM26 | Q5T8P6 | RNA-binding protein 26 | chr13 | Not Cancer Driver | No | 1 | intact, hippie | 117 | 834 | 100 | 100 | 0 |
RBX1 | RBX1 | P62877 | E3 ubiquitin-protein ligase RBX1 | chr22 | Not Cancer Driver | No | 1 | hippie | 10 | 18 | 1 | 1 | 0 |
RC3H1_ENST00000258349 | RC3H1 | Q5TC82 | Roquin-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 158 | 796 | 115 | 115 | 0 |
RELA | RELA | Q04206 | Transcription factor p65 | chr11 | Compendium | Yes | 1 | hippie | 75 | 400 | 48 | 48 | 0 |
RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 1 | hippie | 52 | 19 | 2 | 2 | 0 |
RHOBTB1 | RHOBTB1 | O94844 | Rho-related BTB domain-containing protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 95 | 121 | 19 | 19 | 0 |
RHOBTB2_ENST00000251822 | RHOBTB2 | Q9BYZ6 | Rho-related BTB domain-containing protein 2 | chr8 | Not Cancer Driver | No | 1 | hippie | 99 | 131 | 18 | 18 | 6 |
RHOD | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 10 | 0 | 0 | 0 |
RHOF | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 10 | 0 | 0 | 0 |
RHOG_ENST00000396978 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 22 | 5 | 5 | 0 |
RHOH_ENST00000617441 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | Census | Yes | 1 | hippie | 41 | 12 | 3 | 3 | 0 |
RHOJ | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
RHOV | RHOV | Q96L33 | Rho-related GTP-binding protein RhoV | chr15 | Not Cancer Driver | No | 1 | hippie | 25 | 47 | 5 | 5 | 0 |
RIN2 | RIN2 | Q8WYP3-2 | Isoform 2 of Ras and Rab interactor 2 | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 104 | 342 | 34 | 34 | 0 |
RIN3 | RIN3 | Q8TB24 | Ras and Rab interactor 3 | chr14 | Not Cancer Driver | No | 1 | hippie | 137 | 417 | 61 | 61 | 0 |
RND2 | RND2 | P52198 | Rho-related GTP-binding protein RhoN | chr17 | Not Cancer Driver | No | 1 | hippie | 19 | 54 | 4 | 4 | 0 |
RNF2 | RNF2 | Q99496 | E3 ubiquitin-protein ligase RING2 | chr1 | Not Cancer Driver | No | 1 | hippie | 40 | 203 | 22 | 22 | 0 |
RPL11 | RPL11 | P62913 | 60S ribosomal protein L11 | chr1 | Not Cancer Driver | No | 1 | hippie | 27 | 12 | 1 | 1 | 1 |
RPP38_ENST00000378202 | RPP38 | P78345 | Ribonuclease P protein subunit p38 | chr10 | Not Cancer Driver | No | 1 | hippie | 36 | 118 | 19 | 19 | 0 |
RPS7_ENST00000645674 | RPS7 | P62081 | 40S ribosomal protein S7 | chr2 | Not Cancer Driver | No | 1 | hippie | 29 | 39 | 7 | 7 | 0 |
RRP1B | RRP1B | Q14684 | Ribosomal RNA processing protein 1 homolog B | chr21 | Not Cancer Driver | No | 1 | hippie | 74 | 513 | 48 | 48 | 0 |
RUVBL2 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 62 | 100 | 13 | 13 | 0 |
SAP25_ENST00000538735 | SAP25 | Q8TEE9 | Histone deacetylase complex subunit SAP25 | chr7 | Not Cancer Driver | No | 1 | hippie | 7 | 143 | 6 | 6 | 0 |
SEC61B | SEC61B | P60468 | Protein transport protein Sec61 subunit beta | chr9 | Not Cancer Driver | No | 1 | hippie | 11 | 60 | 7 | 7 | 0 |
SENP3_ENST00000429205 | SENP3 | Q9H4L4 | Sentrin-specific protease 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 53 | 288 | 30 | 30 | 0 |
SERTAD1 | SERTAD1 | Q9UHV2 | SERTA domain-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 24 | 164 | 18 | 18 | 0 |
SFRP4 | SFRP4 | Q6FHJ7 | Secreted frizzled-related protein 4 | chr7 | Census | Yes | 1 | hippie | 81 | 68 | 22 | 22 | 0 |
SIVA1 | SIVA1 | O15304 | Apoptosis regulatory protein Siva | chr14 | Not Cancer Driver | No | 1 | hippie | 20 | 20 | 6 | 6 | 0 |
SIX2 | SIX2 | Q9NPC8 | Homeobox protein SIX2 | chr2 | Census | Yes | 1 | intact, hippie | 53 | 151 | 21 | 21 | 0 |
SLC4A1 | SLC4A1 | P02730 | Band 3 anion transport protein | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 153 | 130 | 23 | 23 | 39 |
SMARCA4 | SMARCA4 | P51532 | Transcription activator BRG1 | chr19 | Census, Compendium | Yes | 1 | hippie | 349 | 1072 | 195 | 195 | 5 |
SNRPA | SNRPA | P09012 | U1 small nuclear ribonucleoprotein A | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 44 | 164 | 24 | 24 | 0 |
SNRPB | SNRPB | P14678 | Small nuclear ribonucleoprotein-associated proteins B and B' | chr20 | Not Cancer Driver | No | 1 | hippie | 39 | 182 | 34 | 34 | 4 |
SOX3 | SOX3 | P41225 | Transcription factor SOX-3 | chrX | Not Cancer Driver | No | 1 | hippie | 63 | 341 | 61 | 61 | 0 |
SOX4 | SOX4 | Q06945 | Transcription factor SOX-4 | chr6 | Not Cancer Driver | No | 1 | hippie | 28 | 400 | 24 | 24 | 4 |
SP1 | SP1 | P08047 | Transcription factor Sp1 | chr12 | Not Cancer Driver | No | 1 | hippie | 96 | 599 | 71 | 71 | 0 |
SPRTN | SPRTN | Q9H040 | DNA-dependent metalloprotease SPRTN | chr1 | Not Cancer Driver | No | 1 | hippie | 73 | 252 | 38 | 38 | 1 |
SRPK2_ENST00000489828 | SRPK2 | P78362 | SRSF protein kinase 2 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 343 | 46 | 46 | 0 |
STK11 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | Census, Compendium | Yes | 1 | hippie | 75 | 135 | 14 | 14 | 9 |
SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
TAF1_ENST00000373790 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | Not Cancer Driver | No | 1 | hippie | 379 | 1152 | 219 | 219 | 5 |
TBRG1 | TBRG1 | Q3YBR2 | Transforming growth factor beta regulator 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 23 | 173 | 7 | 7 | 0 |
TDRD7 | TDRD7 | Q8NHU6 | Tudor domain-containing protein 7 | chr9 | Not Cancer Driver | No | 1 | hippie | 126 | 266 | 38 | 38 | 0 |
TEAD2_ENST00000311227 | TEAD2 | Q15562 | Transcriptional enhancer factor TEF-4 | chr19 | Not Cancer Driver | No | 1 | hippie | 66 | 220 | 31 | 31 | 0 |
TERT | TERT | O14746 | Telomerase reverse transcriptase | chr5 | Census | Yes | 1 | hippie | 110 | 212 | 16 | 16 | 31 |
TFDP1 | TFDP1 | Q14186 | Transcription factor Dp-1 | chr13 | Not Cancer Driver | No | 1 | hippie | 82 | 245 | 47 | 47 | 0 |
TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | Not Cancer Driver | No | 1 | hippie | 41 | 41 | 4 | 4 | 10 |
TMEFF1 | TMEFF1 | Q8IYR6 | Tomoregulin-1 | chr9 | Not Cancer Driver | No | 1 | hippie | 50 | 65 | 9 | 9 | 0 |
TMOD1_ENST00000395211 | TMOD1 | P28289 | Tropomodulin-1 | chr9 | Not Cancer Driver | No | 1 | hippie | 41 | 195 | 29 | 29 | 0 |
TOP1 | TOP1 | P11387 | DNA topoisomerase 1 | chr20 | Census, Compendium | Yes | 1 | hippie | 93 | 391 | 53 | 53 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 2 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
TP63 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | Census, Compendium | Yes | 1 | hippie | 229 | 398 | 143 | 143 | 28 |
TPI1_ENST00000396705 | TPI1 | P60174 | Triosephosphate isomerase | chr12 | Not Cancer Driver | No | 1 | hippie | 40 | 15 | 2 | 2 | 7 |
TPT1_ENST00000530705 | TPT1 | P13693 | Translationally-controlled tumor protein | chr13 | Not Cancer Driver | No | 1 | hippie | 17 | 43 | 6 | 6 | 0 |
TRADD | TRADD | Q15628 | Tumor necrosis factor receptor type 1-associated DEATH domain protein | chr16 | Not Cancer Driver | No | 1 | hippie | 26 | 74 | 5 | 5 | 0 |
TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 430 | 41 | 41 | 0 |
TRIP12_ENST00000283943 | TRIP12 | Q14669 | E3 ubiquitin-protein ligase TRIP12 | chr2 | Not Cancer Driver | No | 1 | hippie | 224 | 845 | 117 | 117 | 4 |
TSC1 | TSC1 | Q92574 | Hamartin | chr9 | Census, Compendium | Yes | 1 | hippie | 135 | 732 | 78 | 78 | 11 |
TTF1 | TTF1 | Q15361 | Transcription termination factor 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 105 | 535 | 59 | 59 | 0 |
TUBA1A | TUBA1A | Q71U36 | Tubulin alpha-1A chain | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 59 | 52 | 11 | 11 | 8 |
TUBA1C_ENST00000301072 | TUBA1C | Q9BQE3 | Tubulin alpha-1C chain | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 39 | 50 | 5 | 5 | 0 |
TUBB | TUBB | P07437 | Tubulin beta chain | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 40 | 63 | 11 | 11 | 5 |
TUBB4B | TUBB4B | P68371 | Tubulin beta-4B chain | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 52 | 65 | 11 | 11 | 2 |
TUBG1 | TUBG1 | P23258 | Tubulin gamma-1 chain | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 44 | 10 | 10 | 3 |
UBE2A | UBE2A | P49459 | Ubiquitin-conjugating enzyme E2 A | chrX | Compendium | Yes | 1 | hippie | 35 | 67 | 13 | 13 | 2 |
UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | Not Cancer Driver | No | 1 | hippie | 16 | 16 | 3 | 3 | 0 |
UBE4B | UBE4B | O95155 | Ubiquitin conjugation factor E4 B | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 158 | 434 | 49 | 49 | 0 |
UBL7_ENST00000565335 | UBL7 | Q96S82 | Ubiquitin-like protein 7 | chr15 | Not Cancer Driver | No | 1 | hippie | 31 | 192 | 22 | 22 | 0 |
UCHL1 | UCHL1 | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | chr4 | Not Cancer Driver | No | 1 | hippie | 33 | 34 | 7 | 7 | 4 |
USP26 | USP26 | Q9BXU7 | Ubiquitin carboxyl-terminal hydrolase 26 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 206 | 325 | 75 | 75 | 0 |
VAMP1 | VAMP1 | P23763 | Vesicle-associated membrane protein 1 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 8 | 56 | 4 | 4 | 0 |
VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | Not Cancer Driver | No | 1 | hippie | 88 | 186 | 16 | 16 | 16 |
VHL | VHL | P40337 | von Hippel-Lindau disease tumor suppressor | chr3 | Census, Compendium | Yes | 1 | intact, hippie | 142 | 117 | 36 | 36 | 133 |
WRN | WRN | Q14191 | Werner syndrome ATP-dependent helicase | chr8 | Census, Compendium | Yes | 1 | hippie | 164 | 373 | 41 | 41 | 2 |
YWHAE | YWHAE | P62258 | 14-3-3 protein epsilon | chr17 | Census | Yes | 1 | hippie | 32 | 41 | 3 | 3 | 0 |
YY1 | YY1 | P25490 | Transcriptional repressor protein YY1 | chr14 | Not Cancer Driver | No | 1 | hippie | 37 | 336 | 26 | 26 | 2 |
ZBTB17_ENST00000375743 | ZBTB17 | Q13105 | Zinc finger and BTB domain-containing protein 17 | chr1 | Not Cancer Driver | No | 1 | hippie | 77 | 310 | 30 | 30 | 0 |
ZBTB38_ENST00000441582 | ZBTB38 | Q8NAP3 | Zinc finger and BTB domain-containing protein 38 | chr3 | Not Cancer Driver | No | 1 | hippie | 137 | 648 | 73 | 73 | 0 |
ZC3H18_ENST00000301011 | ZC3H18 | Q86VM9 | Zinc finger CCCH domain-containing protein 18 | chr16 | Not Cancer Driver | No | 1 | hippie | 139 | 929 | 134 | 134 | 0 |
ZDHHC5 | ZDHHC5 | Q9C0B5 | Palmitoyltransferase ZDHHC5 | chr11 | Not Cancer Driver | No | 1 | hippie | 89 | 462 | 63 | 63 | 0 |
ZFP91 | ZFP91 | Q96JP5 | E3 ubiquitin-protein ligase ZFP91 | chr11 | Not Cancer Driver | No | 1 | hippie | 85 | 383 | 55 | 55 | 0 |
ZGRF1 | ZGRF1 | Q86YA3 | Protein ZGRF1 | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 216 | 881 | 95 | 95 | 0 |
ZNF227 | ZNF227 | Q86WZ6 | Zinc finger protein 227 | chr19 | Not Cancer Driver | No | 1 | hippie | 84 | 220 | 27 | 27 | 0 |
ZNF410_ENST00000555044 | ZNF410 | Q86VK4 | Zinc finger protein 410 | chr14 | Not Cancer Driver | No | 1 | hippie | 51 | 309 | 28 | 28 | 0 |
ZNF420 | ZNF420 | Q8TAQ5 | Zinc finger protein 420 | chr19 | Not Cancer Driver | No | 1 | hippie | 110 | 154 | 24 | 24 | 0 |
ZNF687 | ZNF687 | Q8N1G0 | Zinc finger protein 687 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 138 | 776 | 83 | 83 | 1 |
ZUP1 | ZUP1 | Q96AP4 | Zinc finger-containing ubiquitin peptidase 1 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 63 | 204 | 19 | 19 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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