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CDK18_ENST00000360066 ,CDK18 ,Q07002
  • Uniprot Accession= Q07002
  • Ensembl Transcript= ENST00000360066.6
  • Uniprot Name= CDK18
  • Name= Cyclin-dependent kinase 18
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 76
  • Number of Interaction partner in biogrid: 38
  • Number of Interaction partner in hippie: 128
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 42 51 2 2 0
ACKR2 ACKR2 O00590 Atypical chemokine receptor 2 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 70 25 6 6 0
AK8 AK8 Q96MA6 Adenylate kinase 8 chr9 Not Cancer Driver No 1 intact, hippie 74 53 8 8 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 Not Cancer Driver No 2 intact, hippie 98 861 79 79 0
BLZF1 BLZF1 Q9H2G9 Golgin-45 chr1 Not Cancer Driver No 1 intact, hippie 51 218 24 24 0
CA4 CA4 P22748 Carbonic anhydrase 4 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 55 81 12 12 4
CBY1_ENST00000216029 CBY1 Q9Y3M2 Protein chibby homolog 1 chr22 Not Cancer Driver No 2 intact, hippie 13 98 11 11 0
CCDC102B CCDC102B Q68D86 Coiled-coil domain-containing protein 102B chr18 Not Cancer Driver No 1 hippie 133 334 89 89 0
CCDC125_ENST00000396499 CCDC125 Q86Z20 Coiled-coil domain-containing protein 125 chr5 Not Cancer Driver No 1 intact, hippie 58 261 23 23 0
CCDC85B CCDC85B Q15834 Coiled-coil domain-containing protein 85B chr11 Not Cancer Driver No 1 intact, hippie 3 79 2 2 0
CCDC88B CCDC88B A6NC98 Coiled-coil domain-containing protein 88B chr11 Not Cancer Driver No 1 intact, hippie 156 1152 130 130 0
CCND3 CCND3 P30281 G1/S-specific cyclin-D3 chr6 Census, Compendium Yes 1 intact, hippie 29 46 8 8 0
CCNDBP1 CCNDBP1 O95273 Cyclin-D1-binding protein 1 chr15 Not Cancer Driver No 1 hippie 35 63 5 5 0
CCNK CCNK O75909 Cyclin-K chr14 Not Cancer Driver No 2 intact, hippie 39 347 15 15 1
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 Not Cancer Driver No 1 intact, hippie, biogrid 63 46 3 3 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 intact, hippie, biogrid 71 95 12 12 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 Not Cancer Driver No 1 intact, hippie, biogrid 51 92 2 2 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 1 intact, hippie, biogrid 83 72 10 10 1
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 Not Cancer Driver No 1 intact, hippie, biogrid 66 5 1 1 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 1 intact, hippie, biogrid 59 36 6 6 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 Not Cancer Driver No 1 intact, hippie, biogrid 41 36 2 2 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 hippie, biogrid 52 214 31 31 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 40 1 0 0 0
CDK15 CDK15 Q96Q40 Cyclin-dependent kinase 15 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 66 35 4 4 0
CDK16_ENST00000357227 CDK16 Q00536 Cyclin-dependent kinase 16 chrX Not Cancer Driver No 3 hippie, biogrid 55 139 30 30 0
CDK17 CDK17 Q00537 Cyclin-dependent kinase 17 chr12 Not Cancer Driver No 1 hippie, biogrid 76 198 26 26 0
CDK18_ENST00000360066 CDK18 Q07002 Cyclin-dependent kinase 18 chr1 Not Cancer Driver No 1 hippie 64 132 17 17 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 Not Cancer Driver No 1 intact, hippie 48 5 1 1 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 hippie, biogrid 48 121 30 30 0
CDR2 CDR2 Q01850 Cerebellar degeneration-related protein 2 chr16 Not Cancer Driver No 1 hippie 50 287 26 26 0
CEP76 CEP76 Q8TAP6 Centrosomal protein of 76 kDa chr18 Not Cancer Driver No 1 intact, hippie 63 96 7 7 0
CHTOP_ENST00000368694 CHTOP Q9Y3Y2 Chromatin target of PRMT1 protein chr1 Not Cancer Driver No 1 hippie, biogrid 36 244 34 34 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 Census, Compendium Yes 1 hippie, biogrid 247 1212 214 214 148
COL1A2 COL1A2 P08123 Collagen alpha-2(I) chain chr7 Not Cancer Driver No 1 hippie, biogrid 372 1159 329 329 83
CTSB CTSB P07858 Cathepsin B chr8 Not Cancer Driver No 1 hippie 41 7 2 2 0
DNLZ DNLZ Q5SXM8 DNL-type zinc finger protein chr9 Not Cancer Driver No 3 intact, hippie, biogrid 15 72 9 9 0
DPF2_ENST00000528416 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 Not Cancer Driver No 1 hippie 67 179 30 30 5
DUSP7 DUSP7 Q16829 Dual specificity protein phosphatase 7 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 40 139 5 5 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 135 447 73 73 0
EEF2 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 intact, hippie 111 78 14 14 1
EIF3I EIF3I Q13347 Eukaryotic translation initiation factor 3 subunit I chr1 Not Cancer Driver No 1 intact, hippie 47 46 6 6 0
ENG ENG P17813 Endoglin chr9 Not Cancer Driver No 1 intact, hippie 60 114 15 15 32
EYA2 EYA2 O00167 Eyes absent homolog 2 chr20 Not Cancer Driver No 1 intact, hippie 107 204 50 50 0
FAAP100 FAAP100 Q0VG06 Fanconi anemia core complex-associated protein 100 chr17 Not Cancer Driver No 1 intact, hippie 93 207 31 31 0
FCHSD2 FCHSD2 O94868 F-BAR and double SH3 domains protein 2 chr11 Not Cancer Driver No 1 hippie 61 391 30 30 0
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 Not Cancer Driver No 2 hippie, biogrid 85 52 8 8 0
FKBP5 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 70 150 20 20 0
FSD2 FSD2 A1L4K1 Fibronectin type III and SPRY domain-containing protein 2 chr15 Not Cancer Driver No 1 hippie 116 300 60 60 0
FUBP3 FUBP3 Q96I24 Far upstream element-binding protein 3 chr9 Not Cancer Driver No 1 intact, hippie 68 353 51 51 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 2 intact, hippie 88 312 53 53 0
GNB4_ENST00000468623 GNB4 Q9HAV0 Guanine nucleotide-binding protein subunit beta-4 chr3 Not Cancer Driver No 1 intact, hippie 49 27 3 3 2
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 2 intact, hippie 115 854 96 96 0
GORASP2 GORASP2 Q9H8Y8 Golgi reassembly-stacking protein 2 chr2 Not Cancer Driver No 1 intact, hippie 55 287 31 31 0
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 Not Cancer Driver No 1 hippie 97 454 60 60 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 55 319 41 41 0
HNRNPUL2 HNRNPUL2 Q1KMD3 Heterogeneous nuclear ribonucleoprotein U-like protein 2 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 71 418 35 35 0
HOMER3_ENST00000542541 HOMER3 Q9NSC5 Homer protein homolog 3 chr19 Not Cancer Driver No 1 intact, hippie 31 251 15 15 0
HOOK2 HOOK2 Q96ED9 Protein Hook homolog 2 chr19 Not Cancer Driver No 1 intact, hippie 94 487 62 62 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 4 hippie, biogrid 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 3 intact, hippie, biogrid 100 254 43 43 0
IKZF3 IKZF3 Q9UKT9 Zinc finger protein Aiolos chr17 Census, Compendium Yes 1 hippie 106 284 60 60 1
INCA1_ENST00000576820 INCA1 Q0VD86 Protein INCA1 chr17 Not Cancer Driver No 1 intact, hippie 18 195 14 14 0
KANK2_ENST00000586659 KANK2 Q63ZY3 KN motif and ankyrin repeat domain-containing protein 2 chr19 Not Cancer Driver No 1 hippie 107 531 71 71 3
KATNAL1_ENST00000380617 KATNAL1 Q9BW62 Katanin p60 ATPase-containing subunit A-like 1 chr13 Not Cancer Driver No 1 hippie 49 181 17 17 0
KIFC3_ENST00000379655 KIFC3 Q9BVG8 Kinesin-like protein KIFC3 chr16 Not Cancer Driver No 1 intact, hippie 84 487 42 42 0
KRT15_ENST00000393976 KRT15 P19012 Keratin, type I cytoskeletal 15 chr17 Not Cancer Driver No 1 intact, hippie 95 191 34 34 0
KRT16 KRT16 P08779 Keratin, type I cytoskeletal 16 chr17 Not Cancer Driver No 1 intact, hippie 83 152 28 28 16
KRT31 KRT31 Q15323 Keratin, type I cuticular Ha1 chr17 Not Cancer Driver No 1 hippie 116 64 16 16 0
KRT34 KRT34 O76011 Keratin, type I cuticular Ha4 chr17 Not Cancer Driver No 1 hippie 102 58 21 21 0
KRT40_ENST00000398486 KRT40 Q6A162 Keratin, type I cytoskeletal 40 chr17 Not Cancer Driver No 1 intact, hippie 70 6 1 1 0
KRT75 KRT75 O95678 Keratin, type II cytoskeletal 75 chr12 Not Cancer Driver No 1 intact, hippie 126 142 35 35 1
KRT86 KRT86 O43790 Keratin, type II cuticular Hb6 chr12 Not Cancer Driver No 1 intact 58 27 5 5 8
LARP4B LARP4B Q92615 La-related protein 4B chr10 Census Yes 1 hippie 127 521 91 91 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie 78 508 66 66 0
MAD1L1_ENST00000399654 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 Not Cancer Driver No 1 hippie 117 526 77 77 0
MAGED2 MAGED2 Q9UNF1 Melanoma-associated antigen D2 chrX Not Cancer Driver No 1 hippie 99 326 53 53 1
MASTL MASTL Q96GX5 Serine/threonine-protein kinase greatwall chr10 Not Cancer Driver No 1 hippie 90 389 44 44 0
MID2 MID2 Q9UJV3 Probable E3 ubiquitin-protein ligase MID2 chrX Not Cancer Driver No 1 hippie 112 95 24 24 1
MIPOL1 MIPOL1 Q8TD10 Mirror-image polydactyly gene 1 protein chr14 Not Cancer Driver No 1 intact, hippie 58 273 37 37 0
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 78 283 32 32 0
MTR MTR Q99707 Methionine synthase chr1 Not Cancer Driver No 1 hippie 151 104 17 17 2
MTUS2 MTUS2 Q5JR59 Microtubule-associated tumor suppressor candidate 2 chr13 Not Cancer Driver No 2 intact, hippie 370 1208 329 329 0
NSRP1 NSRP1 Q9H0G5 Nuclear speckle splicing regulatory protein 1 chr17 Not Cancer Driver No 1 intact, hippie 61 521 56 56 0
NTPCR NTPCR Q9BSD7 Cancer-related nucleoside-triphosphatase chr1 Not Cancer Driver No 1 hippie 30 31 2 2 0
NUTM1_ENST00000614490 NUTM1 Q86Y26 NUT family member 1 chr15 Census Yes 1 hippie 202 967 175 175 0
P3H1_ENST00000296388 P3H1 Q32P28 Prolyl 3-hydroxylase 1 chr1 Not Cancer Driver No 1 intact, hippie 91 177 18 18 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 Not Cancer Driver No 1 intact, hippie 83 419 45 45 2
PNMA1 PNMA1 Q8ND90 Paraneoplastic antigen Ma1 chr14 Not Cancer Driver No 1 intact, hippie 48 56 9 9 0
PPFIA1 PPFIA1 Q13136 Liprin-alpha-1 chr11 Not Cancer Driver No 1 hippie 164 865 126 126 0
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 Not Cancer Driver No 1 intact, hippie 37 12 0 0 0
PPP5C PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 Not Cancer Driver No 1 hippie 70 73 12 12 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie, biogrid 53 24 0 0 2
RAB3IP RAB3IP Q96QF0 Rab-3A-interacting protein chr12 Not Cancer Driver No 1 hippie 85 227 33 33 0
RABEP1 RABEP1 Q15276 Rab GTPase-binding effector protein 1 chr17 Census, Compendium Yes 1 hippie 81 520 57 57 0
RALY RALY Q9UKM9 RNA-binding protein Raly chr20 Not Cancer Driver No 1 hippie, biogrid 58 187 32 32 0
RBM4_ENST00000310092 RBM4 Q9BWF3 RNA-binding protein 4 chr11 Not Cancer Driver No 1 intact, hippie 40 129 12 12 0
REL REL Q04864 Proto-oncogene c-Rel chr2 Census Yes 1 intact, hippie 68 363 43 43 0
RPL37A RPL37A P61513 60S ribosomal protein L37a chr2 Not Cancer Driver No 1 intact, hippie 4 0 0 0 0
S100B S100B P04271 Protein S100-B chr21 Not Cancer Driver No 1 hippie, biogrid 17 13 1 1 0
SEC23A SEC23A Q15436 Protein transport protein Sec23A chr14 Not Cancer Driver No 1 intact, hippie 100 73 8 8 1
SEC24D SEC24D O94855 Protein transport protein Sec24D chr4 Not Cancer Driver No 1 hippie 130 319 45 45 2
SFXN2 SFXN2 Q96NB2 Sideroflexin-2 chr10 Not Cancer Driver No 3 intact, hippie, biogrid 44 0 0 0 0
SPERT CBY2 Q8NA61 Protein chibby homolog 2 chr13 Not Cancer Driver No 1 intact 103 340 82 82 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie 35 112 14 14 12
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 Not Cancer Driver No 1 hippie, biogrid 54 55 10 10 0
TRAF1 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 Not Cancer Driver No 1 intact, hippie 51 63 9 9 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 1 intact, hippie 63 4 1 1 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 intact, hippie 59 87 11 11 0
TRIM50_ENST00000453152 TRIM50 Q86XT4 E3 ubiquitin-protein ligase TRIM50 chr7 Not Cancer Driver No 1 intact, hippie 63 80 11 11 0
TRIM54_ENST00000380075 TRIM54 Q9BYV2 Tripartite motif-containing protein 54 chr2 Not Cancer Driver No 1 intact, hippie 63 98 17 17 0
TRPS1_ENST00000220888 TRPS1 Q9UHF7 Zinc finger transcription factor Trps1 chr8 Not Cancer Driver No 1 hippie 348 800 216 216 7
TSGA10_ENST00000355053 TSGA10 Q9BZW7 Testis-specific gene 10 protein chr2 Not Cancer Driver No 1 hippie 112 477 76 76 0
TTC23 TTC23 Q5W5X9 Tetratricopeptide repeat protein 23 chr15 Not Cancer Driver No 1 hippie 42 109 13 13 0
TTC29_ENST00000325106 TTC29 Q8NA56 Tetratricopeptide repeat protein 29 chr4 Not Cancer Driver No 3 intact, hippie, biogrid 105 64 12 12 0
UBL4A UBL4A P11441 Ubiquitin-like protein 4A chrX Not Cancer Driver No 2 intact, hippie 22 16 5 5 0
VPS28_ENST00000292510 VPS28 Q9UK41 Vacuolar protein sorting-associated protein 28 homolog chr8 Not Cancer Driver No 1 intact, hippie 28 31 5 5 0
VPS52 VPS52 Q8N1B4 Vacuolar protein sorting-associated protein 52 homolog chr6 Not Cancer Driver No 1 hippie 89 36 5 5 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 3 intact, hippie, biogrid 22 109 4 4 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 intact, hippie, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 3 intact, hippie, biogrid 15 55 3 3 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 3 intact, hippie, biogrid 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 3 intact, hippie, biogrid 30 81 10 10 0
ZNF426 ZNF426 Q9BUY5 Zinc finger protein 426 chr19 Not Cancer Driver No 1 intact, hippie 64 24 4 4 0
ZNF438 ZNF438 Q7Z4V0 Zinc finger protein 438 chr10 Not Cancer Driver No 1 intact, hippie 123 612 90 90 0
ZNF774 ZNF774 Q6NX45 Zinc finger protein 774 chr15 Not Cancer Driver No 1 intact, hippie 61 233 30 30 0
ZRANB1 ZRANB1 Q9UGI0 Ubiquitin thioesterase ZRANB1 chr10 Not Cancer Driver No 1 hippie 87 158 25 25 0