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CDC7 ,CDC7 ,O00311
  • Uniprot Accession= O00311
  • Ensembl Transcript= ENST00000428239.5
  • Uniprot Name= CDC7
  • Name= Cell division cycle 7-related protein kinase
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 44
  • Number of Interaction partner in biogrid: 16
  • Number of Interaction partner in hippie: 85
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AMY1A AMY1A P0DUB6 Alpha-amylase 1A chr1 Not Cancer Driver No 1 intact, hippie, biogrid 20 29 0 0 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARF1_ENST00000272102 ARF1 P84077 ADP-ribosylation factor 1 chr1 Not Cancer Driver No 1 intact 30 4 2 2 2
BANP_ENST00000286122 BANP Q8N9N5 Protein BANP chr16 Not Cancer Driver No 1 intact, hippie 74 311 43 43 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 intact, hippie 42 212 19 19 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CDC7 CDC7 O00311 Cell division cycle 7-related protein kinase chr1 Not Cancer Driver No 2 intact, hippie 72 185 24 24 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 Census, Compendium Yes 1 intact, hippie 52 52 5 5 3
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 intact, hippie 50 34 2 2 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 intact, hippie 48 121 30 30 0
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 Census, Compendium Yes 1 intact, hippie 166 83 88 88 36
CENPJ CENPJ Q9HC77 Centromere protein J chr13 Not Cancer Driver No 1 hippie 176 1176 158 158 1
CHAF1A CHAF1A Q13111 Chromatin assembly factor 1 subunit A chr19 Not Cancer Driver No 1 intact, hippie 133 767 99 99 0
CLSPN CLSPN Q9HAW4 Claspin chr1 Not Cancer Driver No 1 hippie 151 1283 147 147 0
COLGALT1 COLGALT1 Q8NBJ5 Procollagen galactosyltransferase 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 89 114 11 11 3
DBF4 DBF4 Q9UBU7 Protein DBF4 homolog A chr7 Not Cancer Driver No 12 intact, hippie, biogrid 75 333 26 26 0
DBF4B DBF4B Q8NFT6 Protein DBF4 homolog B chr17 Not Cancer Driver No 4 intact, hippie, biogrid 68 311 22 22 0
DIAPH1 DIAPH1 O60610 Protein diaphanous homolog 1 chr5 Not Cancer Driver No 1 hippie 118 692 57 57 1
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DTD1 DTD1 Q8TEA8 D-aminoacyl-tRNA deacylase 1 chr20 Not Cancer Driver No 1 hippie 45 93 26 26 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 intact, hippie 88 312 53 53 0
GMEB2_ENST00000370077 GMEB2 Q9UKD1 Glucocorticoid modulatory element-binding protein 2 chr20 Not Cancer Driver No 1 hippie 84 274 39 39 0
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 intact, hippie 115 854 96 96 0
GOLGA6A GOLGA6A Q9NYA3 Golgin subfamily A member 6A chr15 Not Cancer Driver No 1 intact, hippie 51 633 44 44 0
GPT_ENST00000528431 GPT P24298 Alanine aminotransferase 1 chr8 Not Cancer Driver No 1 intact, hippie 52 51 9 9 0
GRHPR GRHPR Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase chr9 Not Cancer Driver No 1 hippie 31 36 4 4 0
HADHB HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie, biogrid 71 41 9 9 14
HDGFL2 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 Not Cancer Driver No 1 hippie 59 622 57 57 0
HHIPL1 HHIPL1 Q96JK4 HHIP-like protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 73 161 9 9 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 55 319 41 41 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 Census Yes 1 hippie, biogrid 12 109 12 12 0
HOMEZ HOMEZ Q8IX15 Homeobox and leucine zipper protein Homez chr14 Not Cancer Driver No 1 hippie 83 401 70 70 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 336 666 69 69 2
ICE1 ICE1 Q9Y2F5 Little elongation complex subunit 1 chr5 Not Cancer Driver No 1 intact, hippie 360 1666 265 265 0
IFT122_ENST00000348417 IFT122 Q9HBG6 Intraflagellar transport protein 122 homolog chr3 Not Cancer Driver No 1 hippie 157 54 5 5 5
IGF2BP2_ENST00000382199 IGF2BP2 Q9Y6M1 Insulin-like growth factor 2 mRNA-binding protein 2 chr3 Census Yes 1 hippie, biogrid 68 237 31 31 0
IKZF1 IKZF1 Q13422 DNA-binding protein Ikaros chr7 Census, Compendium Yes 1 intact, hippie 143 326 92 92 5
IKZF3 IKZF3 Q9UKT9 Zinc finger protein Aiolos chr17 Census, Compendium Yes 1 hippie 106 284 60 60 1
IKZF4_ENST00000547167 IKZF4 Q9H2S9 Zinc finger protein Eos chr12 Not Cancer Driver No 1 intact, hippie 69 417 57 57 0
IL13RA2_ENST00000243213 IL13RA2 Q14627 Interleukin-13 receptor subunit alpha-2 chrX Not Cancer Driver No 1 hippie, biogrid 69 0 0 0 0
IMMT IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie, biogrid 97 400 50 50 0
KMT2E KMT2E Q8IZD2 Inactive histone-lysine N-methyltransferase 2E chr7 Not Cancer Driver No 1 hippie 233 1613 198 198 4
LZTS1 LZTS1 Q9Y250 Leucine zipper putative tumor suppressor 1 chr8 Not Cancer Driver No 1 intact, hippie 102 467 75 75 0
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 79 165 20 20 0
MCM10 MCM10 Q7L590 Protein MCM10 homolog chr10 Not Cancer Driver No 1 intact, hippie 152 535 102 102 1
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 2 intact, hippie 104 275 38 38 1
MCM3_ENST00000229854 MCM3 P25205 DNA replication licensing factor MCM3 chr6 Not Cancer Driver No 2 intact, hippie 92 310 47 47 0
MCM4 MCM4 P33991 DNA replication licensing factor MCM4 chr8 Not Cancer Driver No 1 hippie 121 215 35 35 0
MCM5 MCM5 P33992 DNA replication licensing factor MCM5 chr22 Not Cancer Driver No 1 hippie 88 109 20 20 1
MCM6 MCM6 Q14566 DNA replication licensing factor MCM6 chr2 Not Cancer Driver No 1 hippie 101 122 13 13 0
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 Not Cancer Driver No 1 hippie 101 128 22 22 0
MCMBP MCMBP Q9BTE3 Mini-chromosome maintenance complex-binding protein chr10 Not Cancer Driver No 2 intact, hippie 71 136 14 14 0
MEOX2 MEOX2 P50222 Homeobox protein MOX-2 chr7 Not Cancer Driver No 1 intact, hippie 70 274 63 63 0
MRPL2 MRPL2 Q5T653 39S ribosomal protein L2, mitochondrial chr6 Not Cancer Driver No 1 intact, hippie, biogrid 43 132 17 17 0
MTUS2 MTUS2 Q5JR59 Microtubule-associated tumor suppressor candidate 2 chr13 Not Cancer Driver No 1 intact, hippie 370 1208 329 329 0
NDUFB2_ENST00000247866 NDUFB2 O95178 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial chr7 Not Cancer Driver No 1 hippie 13 26 3 3 0
NUP210 NUP210 Q8TEM1 Nuclear pore membrane glycoprotein 210 chr3 Not Cancer Driver No 1 hippie, biogrid 262 156 19 19 0
ORC1_ENST00000371566 ORC1 Q13415 Origin recognition complex subunit 1 chr1 Not Cancer Driver No 1 hippie 100 338 46 46 5
ORC5 ORC5 O43913 Origin recognition complex subunit 5 chr7 Not Cancer Driver No 1 intact, hippie 43 16 2 2 0
ORC6 ORC6 Q9Y5N6 Origin recognition complex subunit 6 chr16 Not Cancer Driver No 2 intact, hippie 23 69 10 10 1
PAF1 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 77 378 56 56 0
PGK1 PGK1 P00558 Phosphoglycerate kinase 1 chrX Not Cancer Driver No 1 hippie 61 40 5 5 9
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLOD1 PLOD1 Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 86 12 0 0 5
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PSIP1_ENST00000380738 PSIP1 O75475 PC4 and SFRS1-interacting protein chr9 Census, Compendium Yes 1 hippie 75 481 71 71 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 Not Cancer Driver No 1 hippie 34 13 0 0 0
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie 59 328 43 43 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie 119 232 34 34 3
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 intact 50 69 3 3 0
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 intact 53 26 4 4 0
SERTAD2 SERTAD2 Q14140 SERTA domain-containing protein 2 chr2 Not Cancer Driver No 1 intact, hippie 37 258 31 31 0
SHLD2_ENST00000298784 SHLD2 Q86V20 Shieldin complex subunit 2 chr10 Not Cancer Driver No 1 hippie 84 157 14 14 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SOCS6_ENST00000582322 SOCS6 O14544 Suppressor of cytokine signaling 6 chr18 Not Cancer Driver No 1 hippie 81 299 48 48 0
STAM2 STAM2 O75886 Signal transducing adapter molecule 2 chr2 Not Cancer Driver No 1 intact, hippie 69 291 30 30 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 Not Cancer Driver No 1 hippie 16 3 0 0 0
TOB1 TOB1 P50616 Protein Tob1 chr17 Not Cancer Driver No 1 hippie 35 214 18 18 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 intact, hippie 59 87 11 11 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
TSNAXIP1_ENST00000388833 TSNAXIP1 Q2TAA8 Translin-associated factor X-interacting protein 1 chr16 Not Cancer Driver No 1 hippie 93 237 37 37 0
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 50 52 3 3 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
ZBTB10 ZBTB10 Q96DT7 Zinc finger and BTB domain-containing protein 10 chr8 Not Cancer Driver No 1 intact, hippie 59 531 32 32 0
ZBTB26_ENST00000373654 ZBTB26 Q9HCK0 Zinc finger and BTB domain-containing protein 26 chr9 Not Cancer Driver No 1 intact, hippie 45 137 14 14 0
ZBTB8B ZBTB8B Q8NAP8 Zinc finger and BTB domain-containing protein 8B chr1 Not Cancer Driver No 1 intact, hippie 21 204 12 12 0