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CDC42BPA_ENST00000334218 ,CDC42BPA ,Q5VT25
  • Uniprot Accession= Q5VT25
  • Ensembl Transcript= ENST00000334218.9
  • Uniprot Name= CDC42BPA
  • Name= Serine/threonine-protein kinase MRCK alpha
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 25
  • Number of Interaction partner in biogrid: 55
  • Number of Interaction partner in hippie: 111
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 Census Yes 1 hippie 248 1247 180 180 0
AL662899.2_ENST00000375880 CSNK2B Q5SRQ3 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie, biogrid 21 30 1 1 0
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 18 5 0 0 0
BCL2L12 BCL2L12 Q9HB09 Bcl-2-like protein 12 chr19 Census, Compendium Yes 1 hippie, biogrid 40 132 10 10 0
C11orf52 C11orf52 Q96A22 Uncharacterized protein C11orf52 chr11 Not Cancer Driver No 1 hippie, biogrid 15 108 12 12 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
CDC42BPA_ENST00000334218 CDC42BPA Q5VT25 Serine/threonine-protein kinase MRCK alpha chr1 Not Cancer Driver No 2 intact, hippie 215 717 80 80 0
CDC42BPB CDC42BPB Q9Y5S2 Serine/threonine-protein kinase MRCK beta chr14 Not Cancer Driver No 1 hippie 185 696 92 92 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 3 intact, hippie 39 23 2 2 1
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie 50 34 2 2 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 Not Cancer Driver No 1 hippie, biogrid 17 44 3 3 0
CENPQ CENPQ Q7L2Z9 Centromere protein Q chr6 Not Cancer Driver No 1 intact, hippie 33 183 23 23 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie, biogrid 20 19 0 0 4
CTDSPL2 CTDSPL2 Q05D32 CTD small phosphatase-like protein 2 chr15 Not Cancer Driver No 1 hippie 47 256 27 27 0
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 51 98 19 19 0
DIRAS3_ENST00000646789 DIRAS3 O95661 GTP-binding protein Di-Ras3 chr1 Not Cancer Driver No 1 hippie, biogrid 38 21 3 3 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 Not Cancer Driver No 1 hippie, biogrid 23 46 6 6 1
DNAJC5B DNAJC5B Q9UF47 DnaJ homolog subfamily C member 5B chr8 Not Cancer Driver No 1 hippie, biogrid 64 31 7 7 0
DNAJC7 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 Not Cancer Driver No 1 hippie, biogrid 41 102 9 9 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 151 8 1 1 0
EBAG9_ENST00000620557 EBAG9 O00559 Receptor-binding cancer antigen expressed on SiSo cells chr8 Not Cancer Driver No 1 hippie, biogrid 35 173 29 29 0
EPB41L4A_ENST00000621003 EPB41L4A Q9HCS5 Band 4.1-like protein 4A chr5 Not Cancer Driver No 1 hippie, biogrid 119 378 65 65 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
EZR EZR P15311 Ezrin chr6 Census Yes 1 hippie, biogrid 66 295 35 35 0
FAM167A FAM167A Q96KS9 Protein FAM167A chr8 Not Cancer Driver No 2 intact, hippie, biogrid 33 116 17 17 0
FCGR1A FCGR1A P12314 High affinity immunoglobulin gamma Fc receptor I chr1 Not Cancer Driver No 2 intact, hippie, biogrid 62 37 5 5 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 43 122 15 15 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX Not Cancer Driver No 1 intact, hippie 124 327 70 70 3
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie, biogrid 86 110 26 26 50
GJD3 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 5 79 0 0 0
GPRC5B_ENST00000569479 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 Not Cancer Driver No 1 hippie, biogrid 82 75 19 19 0
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 Not Cancer Driver No 1 hippie, biogrid 69 17 2 2 3
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 intact, hippie 47 135 10 10 0
HIST1H1C H1-2 P16403 Histone H1.2 chr6 Not Cancer Driver No 1 intact 79 211 78 78 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 intact, hippie 77 504 45 45 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 intact, hippie, biogrid 107 16 4 4 18
IFT57 IFT57 Q9NWB7 Intraflagellar transport protein 57 homolog chr3 Not Cancer Driver No 1 hippie 46 219 18 18 0
INKA2 INKA2 Q9NTI7 PAK4-inhibitor INKA2 chr1 Not Cancer Driver No 2 hippie 41 271 38 38 0
INO80B INO80B Q9C086 INO80 complex subunit B chr2 Not Cancer Driver No 1 hippie, biogrid 35 336 33 33 0
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 Not Cancer Driver No 1 hippie 103 49 11 11 12
KCTD17 KCTD17 Q8N5Z5 BTB/POZ domain-containing protein KCTD17 chr22 Not Cancer Driver No 3 intact, hippie, biogrid 23 187 14 14 1
KIF20B KIF20B Q96Q89 Kinesin-like protein KIF20B chr10 Not Cancer Driver No 1 hippie 217 902 109 109 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 intact, hippie, biogrid 788 7 2 2 27
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 47 93 10 10 0
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie, biogrid 43 55 7 7 1
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie, biogrid 86 94 13 13 1
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 Not Cancer Driver No 1 hippie 108 16 3 3 0
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 Not Cancer Driver No 1 hippie 110 170 30 30 0
LIMK2_ENST00000331728 LIMK2 P53671 LIM domain kinase 2 chr22 Not Cancer Driver No 1 hippie 93 146 29 29 0
LRRC31 LRRC31 Q6UY01 Leucine-rich repeat-containing protein 31 chr3 Not Cancer Driver No 1 hippie 109 80 10 10 0
LURAP1 LURAP1 Q96LR2 Leucine rich adaptor protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 30 169 18 18 0
LURAP1L LURAP1L Q8IV03 Leucine rich adaptor protein 1-like chr9 Not Cancer Driver No 3 intact, hippie, biogrid 31 142 16 16 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 95 84 12 12 0
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 14 328 14 14 0
MLNR MLNR O43193 Motilin receptor chr13 Not Cancer Driver No 1 hippie, biogrid 43 66 6 6 0
MYL12A_ENST00000217652 MYL12A P19105 Myosin regulatory light chain 12A chr18 Not Cancer Driver No 1 intact, hippie 19 70 13 13 0
MYL2 MYL2 P10916 Myosin regulatory light chain 2, ventricular/cardiac muscle isoform chr12 Not Cancer Driver No 1 hippie 44 34 8 8 6
MYL9 MYL9 P24844 Myosin regulatory light polypeptide 9 chr20 Not Cancer Driver No 1 hippie 34 82 19 19 0
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie 268 1237 176 176 0
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
OCLN OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 54 244 21 21 1
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 200 1144 170 170 2
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PPM1A_ENST00000395076 PPM1A P35813 Protein phosphatase 1A chr14 Not Cancer Driver No 1 hippie 60 134 24 24 0
PPP1R12C PPP1R12C Q9BZL4 Protein phosphatase 1 regulatory subunit 12C chr19 Not Cancer Driver No 1 hippie 70 605 55 55 0
PRPS2_ENST00000380668 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX Not Cancer Driver No 1 hippie, biogrid 56 4 1 1 0
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 1 hippie, biogrid 11 52 3 3 0
PTPRM_ENST00000332175 PTPRM P28827 Receptor-type tyrosine-protein phosphatase mu chr18 Not Cancer Driver No 1 intact, hippie 256 365 60 60 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 1 hippie, biogrid 31 43 4 4 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 22 58 4 4 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 biogrid 27 11 0 0 4
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 24 0 0 0 4
RBM8A_ENST00000632555 RBM8A Q9Y5S9 RNA-binding protein 8A chr1 Not Cancer Driver No 1 hippie 35 135 32 32 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 2 hippie, biogrid 52 19 2 2 0
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 20 10 0 0 0
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 18 10 0 0 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 41 12 3 3 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RHOQ RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 Not Cancer Driver No 1 hippie 25 0 0 0 0
RHOU RHOU Q7L0Q8 Rho-related GTP-binding protein RhoU chr1 Not Cancer Driver No 1 hippie 34 63 6 6 0
RHOV RHOV Q96L33 Rho-related GTP-binding protein RhoV chr15 Not Cancer Driver No 1 hippie 25 47 5 5 0
RND1 RND1 Q92730 Rho-related GTP-binding protein Rho6 chr12 Not Cancer Driver No 1 hippie 45 9 1 1 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 19 54 4 4 0
RND3_ENST00000263895 RND3 P61587 Rho-related GTP-binding protein RhoE chr2 Not Cancer Driver No 1 hippie 36 70 10 10 0
RPL28_ENST00000559463 RPL28 P46779 60S ribosomal protein L28 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 29 115 24 24 0
RPL7A RPL7A P62424 60S ribosomal protein L7a chr9 Not Cancer Driver No 1 hippie, biogrid 27 100 5 5 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 37 214 37 37 0
SERBP1 SERBP1 Q8NC51 Plasminogen activator inhibitor 1 RNA-binding protein chr1 Not Cancer Driver No 1 hippie 53 408 53 53 0
SKA3 SKA3 Q8IX90 Spindle and kinetochore-associated protein 3 chr13 Not Cancer Driver No 1 intact, hippie 56 230 32 32 0
SLC31A1 SLC31A1 O15431 High affinity copper uptake protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 22 28 6 6 0
SNAPIN SNAPIN O95295 SNARE-associated protein Snapin chr1 Not Cancer Driver No 1 intact, hippie 9 62 5 5 0
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie 38 416 37 37 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 intact, hippie 96 599 71 71 0
STX4 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 50 152 20 20 0
STX6 STX6 O43752 Syntaxin-6 chr1 Not Cancer Driver No 1 hippie, biogrid 33 78 11 11 0
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 29 164 14 14 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX Not Cancer Driver No 1 intact, hippie 379 1152 219 219 5
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 Not Cancer Driver No 1 intact, hippie 123 107 26 26 0
TIAF1 MYO18A O95411 Putative TGFB1-induced anti-apoptotic factor 1 chr17 Not Cancer Driver No 1 hippie 16 30 5 5 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VPS33A VPS33A Q96AX1 Vacuolar protein sorting-associated protein 33A chr12 Not Cancer Driver No 1 hippie 73 46 8 8 1
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 intact, hippie, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 2 intact, hippie, biogrid 15 55 3 3 0
ZFPL1 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie, biogrid 40 127 16 16 0