Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ANAPC1 | ANAPC1 | Q9H1A4 | Anaphase-promoting complex subunit 1 | chr2 | Not Cancer Driver | No | 2 | intact, hippie | 206 | 263 | 33 | 33 | 0 |
ANAPC10_ENST00000507656 | ANAPC10 | Q9UM13 | Anaphase-promoting complex subunit 10 | chr4 | Not Cancer Driver | No | 3 | intact, hippie | 12 | 65 | 0 | 0 | 0 |
ANAPC11_ENST00000579978 | ANAPC11 | Q9NYG5 | Anaphase-promoting complex subunit 11 | chr17 | Not Cancer Driver | No | 2 | intact, hippie | 7 | 0 | 0 | 0 | 0 |
ANAPC13 | ANAPC13 | Q9BS18 | Anaphase-promoting complex subunit 13 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 5 | 68 | 5 | 5 | 0 |
ANAPC15_ENST00000538393 | ANAPC15 | P60006 | Anaphase-promoting complex subunit 15 | chr11 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 15 | 117 | 14 | 14 | 0 |
ANAPC16 | ANAPC16 | Q96DE5 | Anaphase-promoting complex subunit 16 | chr10 | Not Cancer Driver | No | 3 | hippie, biogrid | 11 | 42 | 4 | 4 | 0 |
ANAPC2 | ANAPC2 | Q9UJX6 | Anaphase-promoting complex subunit 2 | chr9 | Not Cancer Driver | No | 3 | intact, hippie | 104 | 146 | 26 | 26 | 0 |
ANAPC4_ENST00000315368 | ANAPC4 | Q9UJX5 | Anaphase-promoting complex subunit 4 | chr4 | Not Cancer Driver | No | 1 | hippie | 70 | 54 | 1 | 1 | 0 |
ANAPC5 | ANAPC5 | Q9UJX4 | Anaphase-promoting complex subunit 5 | chr12 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 94 | 41 | 4 | 4 | 0 |
ANAPC7 | ANAPC7 | A0A024RBJ3 | Anaphase promoting complex subunit 7, isoform CRA_b | chr12 | Not Cancer Driver | No | 2 | intact, hippie | 74 | 98 | 17 | 17 | 0 |
APBA1 | APBA1 | Q02410 | Amyloid-beta A4 precursor protein-binding family A member 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 149 | 556 | 103 | 103 | 0 |
APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 128 | 418 | 71 | 71 | 17 |
AURKA_ENST00000395915 | AURKA | O14965 | Aurora kinase A | chr20 | Not Cancer Driver | No | 1 | hippie | 36 | 178 | 21 | 21 | 0 |
AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 63 | 8 | 8 | 0 |
AXIN2 | AXIN2 | Q9Y2T1 | Axin-2 | chr17 | Census, Compendium | Yes | 1 | intact, hippie | 114 | 547 | 77 | 77 | 0 |
BANP_ENST00000286122 | BANP | Q8N9N5 | Protein BANP | chr16 | Not Cancer Driver | No | 1 | hippie | 74 | 311 | 43 | 43 | 0 |
BTRC | BTRC | Q9Y297 | F-box/WD repeat-containing protein 1A | chr10 | Not Cancer Driver | No | 1 | hippie | 80 | 45 | 4 | 4 | 0 |
BUB1 | BUB1 | O43683 | Mitotic checkpoint serine/threonine-protein kinase BUB1 | chr2 | Not Cancer Driver | No | 4 | hippie, biogrid | 139 | 466 | 64 | 64 | 0 |
BUB1B | BUB1B | O60566 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta | chr15 | Census | Yes | 5 | intact, hippie, biogrid | 96 | 480 | 35 | 35 | 7 |
BUB3 | BUB3 | O43684 | Mitotic checkpoint protein BUB3 | chr10 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 46 | 60 | 6 | 6 | 0 |
CAPNS1 | CAPNS1 | P04632 | Calpain small subunit 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 58 | 5 | 5 | 0 |
CCDC59 | CCDC59 | Q9P031 | Thyroid transcription factor 1-associated protein 26 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 206 | 27 | 27 | 0 |
CCNA1 | CCNA1 | P78396 | Cyclin-A1 | chr13 | Not Cancer Driver | No | 1 | hippie | 112 | 82 | 21 | 21 | 0 |
CCNA2_ENST00000618014 | CCNA2 | P20248 | Cyclin-A2 | chr4 | Not Cancer Driver | No | 4 | hippie, biogrid | 45 | 186 | 19 | 19 | 0 |
CCNB1 | CCNB1 | P14635 | G2/mitotic-specific cyclin-B1 | chr5 | Not Cancer Driver | No | 1 | hippie | 49 | 145 | 14 | 14 | 0 |
CCNF | CCNF | P41002 | Cyclin-F | chr16 | Not Cancer Driver | No | 1 | hippie | 106 | 221 | 23 | 23 | 3 |
CCT2 | CCT2 | P78371 | T-complex protein 1 subunit beta | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 63 | 46 | 3 | 3 | 0 |
CCT3 | CCT3 | P49368 | T-complex protein 1 subunit gamma | chr1 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 71 | 95 | 12 | 12 | 0 |
CCT4 | CCT4 | P50991 | T-complex protein 1 subunit delta | chr2 | Not Cancer Driver | No | 1 | hippie | 51 | 92 | 2 | 2 | 0 |
CCT5 | CCT5 | P48643 | T-complex protein 1 subunit epsilon | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 83 | 72 | 10 | 10 | 1 |
CCT6A | CCT6A | P40227 | T-complex protein 1 subunit zeta | chr7 | Not Cancer Driver | No | 1 | hippie | 66 | 5 | 1 | 1 | 0 |
CCT7 | CCT7 | Q99832 | T-complex protein 1 subunit eta | chr2 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 59 | 36 | 6 | 6 | 0 |
CCT8 | CCT8 | P50990 | T-complex protein 1 subunit theta | chr21 | Not Cancer Driver | No | 1 | hippie | 41 | 36 | 2 | 2 | 0 |
CDC16_ENST00000356221 | CDC16 | Q13042 | Cell division cycle protein 16 homolog | chr13 | Not Cancer Driver | No | 1 | hippie | 68 | 54 | 7 | 7 | 0 |
CDC20 | CDC20 | Q12834 | Cell division cycle protein 20 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 44 | 198 | 15 | 15 | 0 |
CDC23 | CDC23 | Q9UJX2 | Cell division cycle protein 23 homolog | chr5 | Not Cancer Driver | No | 3 | intact, hippie | 57 | 45 | 6 | 6 | 0 |
CDC25A | CDC25A | P30304 | M-phase inducer phosphatase 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 63 | 313 | 35 | 35 | 0 |
CDC25B | CDC25B | P30305 | M-phase inducer phosphatase 2 | chr20 | Not Cancer Driver | No | 1 | hippie | 80 | 328 | 43 | 43 | 0 |
CDC26 | CDC26 | Q8NHZ8 | Anaphase-promoting complex subunit CDC26 | chr9 | Not Cancer Driver | No | 1 | hippie | 5 | 85 | 5 | 5 | 0 |
CDC27_ENST00000066544 | CDC27 | P30260 | Cell division cycle protein 27 homolog | chr17 | Not Cancer Driver | No | 8 | intact, hippie | 179 | 289 | 75 | 75 | 0 |
CDC5L | CDC5L | Q99459 | Cell division cycle 5-like protein | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 100 | 618 | 77 | 77 | 0 |
CDC6 | CDC6 | Q99741 | Cell division control protein 6 homolog | chr17 | Not Cancer Driver | No | 1 | hippie | 57 | 170 | 15 | 15 | 1 |
CDK1 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | Not Cancer Driver | No | 2 | hippie, biogrid | 40 | 1 | 0 | 0 | 0 |
CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 24 | 0 | 0 | 0 | 0 |
CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | Census, Compendium | Yes | 3 | intact, hippie, biogrid | 48 | 121 | 30 | 30 | 0 |
CDR2 | CDR2 | Q01850 | Cerebellar degeneration-related protein 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 50 | 287 | 26 | 26 | 0 |
CDT1 | CDT1 | Q9H211 | DNA replication factor Cdt1 | chr16 | Not Cancer Driver | No | 1 | hippie | 60 | 377 | 35 | 35 | 5 |
CEP128_ENST00000281129 | CEP128 | Q6ZU80 | Centrosomal protein of 128 kDa | chr14 | Not Cancer Driver | No | 1 | hippie | 195 | 897 | 167 | 167 | 0 |
CHFR | CHFR | Q96EP1 | E3 ubiquitin-protein ligase CHFR | chr12 | Not Cancer Driver | No | 1 | hippie | 85 | 341 | 54 | 54 | 0 |
CILP | CILP | O75339 | Cartilage intermediate layer protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 206 | 278 | 44 | 44 | 0 |
CKS1B | CKS1B | P61024 | Cyclin-dependent kinases regulatory subunit 1 | chr1 | Not Cancer Driver | No | 3 | hippie, biogrid | 10 | 10 | 0 | 0 | 0 |
CKS2 | CKS2 | P33552 | Cyclin-dependent kinases regulatory subunit 2 | chr9 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 9 | 10 | 2 | 2 | 0 |
CLSPN | CLSPN | Q9HAW4 | Claspin | chr1 | Not Cancer Driver | No | 1 | hippie | 151 | 1283 | 147 | 147 | 0 |
COPS5 | COPS5 | Q92905 | COP9 signalosome complex subunit 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 36 | 32 | 7 | 7 | 0 |
CPVL_ENST00000265394 | CPVL | Q9H3G5 | Probable serine carboxypeptidase CPVL | chr7 | Not Cancer Driver | No | 1 | hippie | 81 | 0 | 0 | 0 | 0 |
CREBBP | CREBBP | Q92793 | CREB-binding protein | chr16 | Census, Compendium | Yes | 1 | hippie | 412 | 1796 | 247 | 247 | 33 |
CUEDC2 | CUEDC2 | Q9H467 | CUE domain-containing protein 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 37 | 173 | 25 | 25 | 0 |
CUL1_ENST00000602748 | CUL1 | Q13616 | Cullin-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 151 | 65 | 9 | 9 | 0 |
CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | Census, Compendium | Yes | 1 | hippie | 123 | 167 | 23 | 23 | 3 |
CYP24A1 | CYP24A1 | Q07973 | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | chr20 | Not Cancer Driver | No | 1 | hippie | 74 | 77 | 5 | 5 | 4 |
DAXX_ENST00000266000 | DAXX | Q9UER7 | Death domain-associated protein 6 | chr6 | Census, Compendium | Yes | 1 | hippie | 106 | 549 | 81 | 81 | 0 |
DCPS | DCPS | Q96C86 | m7GpppX diphosphatase | chr11 | Not Cancer Driver | No | 1 | hippie | 48 | 53 | 6 | 6 | 1 |
DDRGK1 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 34 | 181 | 23 | 23 | 0 |
DNAJA2 | DNAJA2 | O60884 | DnaJ homolog subfamily A member 2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 174 | 27 | 27 | 0 |
DSC1 | DSC1 | Q08554 | Desmocollin-1 | chr18 | Not Cancer Driver | No | 1 | hippie | 219 | 265 | 65 | 65 | 0 |
E2F1 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | Not Cancer Driver | No | 1 | hippie | 49 | 272 | 23 | 23 | 0 |
EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
EIF2A | EIF2A | Q9BY44 | Eukaryotic translation initiation factor 2A | chr3 | Not Cancer Driver | No | 1 | hippie | 51 | 162 | 19 | 19 | 0 |
EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 3 | hippie, biogrid | 334 | 1790 | 196 | 196 | 1 |
FBXO31 | FBXO31 | Q5XUX0 | F-box only protein 31 | chr16 | Not Cancer Driver | No | 1 | hippie | 72 | 231 | 30 | 30 | 0 |
FBXO43 | FBXO43 | Q4G163 | F-box only protein 43 | chr8 | Not Cancer Driver | No | 1 | hippie | 98 | 292 | 40 | 40 | 0 |
FBXO5 | FBXO5 | Q9UKT4 | F-box only protein 5 | chr6 | Not Cancer Driver | No | 1 | hippie | 48 | 113 | 13 | 13 | 0 |
FBXW5 | FBXW5 | Q969U6 | F-box/WD repeat-containing protein 5 | chr9 | Not Cancer Driver | No | 1 | hippie | 64 | 74 | 10 | 10 | 0 |
FGFR1_ENST00000447712 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | Census, Compendium | Yes | 1 | hippie | 152 | 230 | 43 | 43 | 74 |
FOXO1 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | Census, Compendium | Yes | 1 | hippie | 81 | 584 | 75 | 75 | 0 |
FRY | FRY | Q5TBA9 | Protein furry homolog | chr13 | Not Cancer Driver | No | 1 | hippie | 463 | 676 | 109 | 109 | 0 |
FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 74 | 184 | 30 | 30 | 0 |
GMNN_ENST00000620958 | GMNN | O75496 | Geminin | chr6 | Not Cancer Driver | No | 1 | hippie | 24 | 206 | 24 | 24 | 1 |
HAX1 | HAX1 | O00165 | HCLS1-associated protein X-1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 219 | 32 | 32 | 2 |
HDAC1 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 47 | 135 | 10 | 10 | 0 |
HDAC2 | HDAC2 | Q92769 | Histone deacetylase 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 46 | 145 | 14 | 14 | 0 |
HDAC6_ENST00000426196 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | Not Cancer Driver | No | 1 | hippie | 178 | 409 | 59 | 59 | 0 |
HECW2_ENST00000644256 | HECW2 | Q9P2P5 | E3 ubiquitin-protein ligase HECW2 | chr2 | Not Cancer Driver | No | 1 | hippie | 348 | 845 | 195 | 195 | 4 |
HHEX | HHEX | Q03014 | Hematopoietically-expressed homeobox protein HHEX | chr10 | Not Cancer Driver | No | 1 | hippie | 23 | 193 | 21 | 21 | 0 |
HIF1AN | HIF1AN | Q9NWT6 | Hypoxia-inducible factor 1-alpha inhibitor | chr10 | Not Cancer Driver | No | 1 | hippie | 37 | 77 | 9 | 9 | 0 |
HNRNPF_ENST00000356053 | HNRNPF | P52597 | Heterogeneous nuclear ribonucleoprotein F | chr10 | Not Cancer Driver | No | 1 | hippie | 65 | 105 | 18 | 18 | 0 |
HOXD13 | HOXD13 | P35453 | Homeobox protein Hox-D13 | chr2 | Census, Compendium | Yes | 1 | hippie | 43 | 113 | 12 | 12 | 9 |
HSF1 | HSF1 | Q00613 | Heat shock factor protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 59 | 335 | 37 | 37 | 0 |
HSF2 | HSF2 | Q03933 | Heat shock factor protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 64 | 292 | 37 | 37 | 0 |
HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | Not Cancer Driver | No | 1 | hippie | 24 | 200 | 13 | 13 | 0 |
HSPA1L | HSPA1L | P34931 | Heat shock 70 kDa protein 1-like | chr6 | Not Cancer Driver | No | 1 | hippie | 119 | 141 | 28 | 28 | 0 |
HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | Not Cancer Driver | No | 1 | hippie | 73 | 282 | 35 | 35 | 0 |
HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | hippie | 149 | 251 | 52 | 52 | 0 |
HSPA9 | HSPA9 | P38646 | Stress-70 protein, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie | 67 | 283 | 26 | 26 | 2 |
HSPD1 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 61 | 82 | 6 | 6 | 2 |
HUWE1_ENST00000262854 | HUWE1 | Q7Z6Z7 | E3 ubiquitin-protein ligase HUWE1 | chrX | Not Cancer Driver | No | 1 | hippie | 669 | 2091 | 329 | 329 | 21 |
ID1 | ID1 | P41134 | DNA-binding protein inhibitor ID-1 | chr20 | Not Cancer Driver | No | 1 | hippie | 20 | 17 | 6 | 6 | 0 |
IST1_ENST00000541571 | IST1 | P53990 | IST1 homolog | chr16 | Not Cancer Driver | No | 1 | hippie | 31 | 185 | 17 | 17 | 0 |
KDM5B_ENST00000367265 | KDM5B | Q9UGL1 | Lysine-specific demethylase 5B | chr1 | Not Cancer Driver | No | 1 | hippie | 219 | 388 | 58 | 58 | 0 |
KIF18A | KIF18A | Q8NI77 | Kinesin-like protein KIF18A | chr11 | Not Cancer Driver | No | 1 | hippie | 114 | 405 | 60 | 60 | 0 |
KNL1 | KNL1 | Q8NG31 | Kinetochore scaffold 1 | chr15 | Census | Yes | 1 | hippie | 272 | 1265 | 135 | 135 | 1 |
KRT31 | KRT31 | Q15323 | Keratin, type I cuticular Ha1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 116 | 64 | 16 | 16 | 0 |
KRT32 | KRT32 | Q14532 | Keratin, type I cuticular Ha2 | chr17 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 88 | 74 | 20 | 20 | 0 |
KRT33A | KRT33A | O76009 | Keratin, type I cuticular Ha3-I | chr17 | Not Cancer Driver | No | 1 | hippie | 84 | 54 | 12 | 12 | 0 |
KRT85 | KRT85 | P78386 | Keratin, type II cuticular Hb5 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 97 | 29 | 4 | 4 | 1 |
KRTAP19-5 | KRTAP19-5 | Q3LI72 | Keratin-associated protein 19-5 | chr21 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 35 | 0 | 0 | 0 | 0 |
KRTAP9-2 | KRTAP9-2 | Q9BYQ4 | Keratin-associated protein 9-2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 0 | 0 | 0 | 0 |
KRTAP9-3 | KRTAP9-3 | Q9BYQ3 | Keratin-associated protein 9-3 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 0 | 0 | 0 | 0 |
LNP1 | LNP1 | A1A4G5 | Leukemia NUP98 fusion partner 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 32 | 145 | 27 | 27 | 0 |
MAB21L2 | MAB21L2 | Q9Y586 | Protein mab-21-like 2 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 6 | 3 | 3 | 5 |
MAD1L1_ENST00000399654 | MAD1L1 | Q9Y6D9 | Mitotic spindle assembly checkpoint protein MAD1 | chr7 | Not Cancer Driver | No | 1 | hippie | 117 | 526 | 77 | 77 | 0 |
MAD2L1 | MAD2L1 | Q13257 | Mitotic spindle assembly checkpoint protein MAD2A | chr4 | Not Cancer Driver | No | 19 | intact, hippie, biogrid | 26 | 12 | 1 | 1 | 0 |
MAD2L1BP_ENST00000372171 | MAD2L1BP | Q15013 | MAD2L1-binding protein | chr6 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 26 | 55 | 7 | 7 | 0 |
MAD2L2 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | Not Cancer Driver | No | 2 | intact, hippie | 22 | 0 | 0 | 0 | 1 |
MAML3 | MAML3 | Q96JK9 | Mastermind-like protein 3 | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 123 | 1119 | 123 | 123 | 0 |
MCL1 | MCL1 | Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 203 | 21 | 21 | 0 |
MDC1 | MDC1 | Q14676 | Mediator of DNA damage checkpoint protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 249 | 1829 | 223 | 223 | 0 |
MOV10_ENST00000357443 | MOV10 | Q9HCE1 | Helicase MOV-10 | chr1 | Not Cancer Driver | No | 1 | hippie | 110 | 101 | 8 | 8 | 0 |
MXI1_ENST00000239007 | MXI1 | P50539 | Max-interacting protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 22 | 187 | 18 | 18 | 1 |
MYBL2 | MYBL2 | P10244 | Myb-related protein B | chr20 | Not Cancer Driver | No | 1 | hippie | 111 | 506 | 85 | 85 | 0 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
NEDD8 | NEDD8 | Q15843 | NEDD8 | chr14 | Not Cancer Driver | No | 1 | hippie | 10 | 36 | 5 | 5 | 0 |
NEK2 | NEK2 | P51955 | Serine/threonine-protein kinase Nek2 | chr1 | Not Cancer Driver | No | 1 | hippie | 61 | 92 | 19 | 19 | 0 |
NINL | NINL | Q9Y2I6 | Ninein-like protein | chr20 | Not Cancer Driver | No | 1 | hippie | 230 | 881 | 150 | 150 | 0 |
NUP98_ENST00000359171 | NUP98 | P52948 | Nuclear pore complex protein Nup98-Nup96 | chr11 | Census | Yes | 1 | hippie | 227 | 1008 | 107 | 107 | 0 |
OTUD7B | OTUD7B | Q6GQQ9 | OTU domain-containing protein 7B | chr1 | Not Cancer Driver | No | 1 | hippie | 124 | 537 | 87 | 87 | 0 |
PAXIP1 | PAXIP1 | Q6ZW49 | PAX-interacting protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 120 | 461 | 39 | 39 | 0 |
PBRM1_ENST00000296302 | PBRM1 | Q86U86 | Protein polybromo-1 | chr3 | Census, Compendium | Yes | 1 | hippie | 209 | 703 | 77 | 77 | 0 |
PCDHAC2 | PCDHAC2 | Q9Y5I4 | Protocadherin alpha-C2 | chr5 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 215 | 416 | 94 | 94 | 0 |
PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | Not Cancer Driver | No | 1 | hippie | 30 | 22 | 3 | 3 | 1 |
PHF8 | PHF8 | Q9UPP1 | Histone lysine demethylase PHF8 | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 154 | 603 | 93 | 93 | 1 |
PIM1 | PIM1 | P11309 | Serine/threonine-protein kinase pim-1 | chr6 | Census, Compendium | Yes | 1 | hippie | 71 | 27 | 8 | 8 | 0 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
PLEKHO2 | PLEKHO2 | Q8TD55 | Pleckstrin homology domain-containing family O member 2 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 402 | 56 | 56 | 0 |
PLK1 | PLK1 | P53350 | Serine/threonine-protein kinase PLK1 | chr16 | Not Cancer Driver | No | 1 | hippie | 87 | 119 | 13 | 13 | 0 |
PPP2CA | PPP2CA | P67775 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | chr5 | Not Cancer Driver | No | 1 | hippie | 41 | 12 | 1 | 1 | 8 |
PPP2CB | PPP2CB | P62714 | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform | chr8 | Not Cancer Driver | No | 1 | hippie | 37 | 12 | 0 | 0 | 0 |
PPP2R1A | PPP2R1A | P30153 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | chr19 | Census, Compendium | Yes | 1 | hippie | 179 | 0 | 0 | 0 | 4 |
PPP2R5A | PPP2R5A | Q15172 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform | chr1 | Not Cancer Driver | No | 1 | hippie | 55 | 93 | 5 | 5 | 0 |
PPP2R5E | PPP2R5E | Q16537 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform | chr14 | Not Cancer Driver | No | 1 | hippie | 68 | 86 | 20 | 20 | 0 |
PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | Not Cancer Driver | No | 1 | hippie | 110 | 78 | 15 | 15 | 31 |
PTTG1_ENST00000520452 | PTTG1 | O95997 | Securin | chr5 | Not Cancer Driver | No | 1 | hippie | 17 | 141 | 6 | 6 | 0 |
RASSF1 | RASSF1 | Q9NS23 | Ras association domain-containing protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 36 | 79 | 3 | 3 | 0 |
RAVER1_ENST00000615032 | RAVER1 | Q8IY67 | Ribonucleoprotein PTB-binding 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 61 | 330 | 22 | 22 | 0 |
RDH14 | RDH14 | Q9HBH5 | Retinol dehydrogenase 14 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 21 | 0 | 0 | 0 |
RELA | RELA | Q04206 | Transcription factor p65 | chr11 | Compendium | Yes | 1 | hippie | 75 | 400 | 48 | 48 | 0 |
RNF34_ENST00000361234 | RNF34 | Q969K3 | E3 ubiquitin-protein ligase RNF34 | chr12 | Not Cancer Driver | No | 1 | hippie | 30 | 112 | 7 | 7 | 0 |
RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
RNH1_ENST00000397604 | RNH1 | P13489 | Ribonuclease inhibitor | chr11 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 40 | 0 | 0 | 0 | 0 |
RPL23_ENST00000394332 | RPL23 | P62829 | 60S ribosomal protein L23 | chr17 | Not Cancer Driver | No | 1 | hippie | 14 | 29 | 4 | 4 | 0 |
RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 48 | 4 | 4 | 0 |
SAMM50 | SAMM50 | Q9Y512 | Sorting and assembly machinery component 50 homolog | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 34 | 1 | 1 | 0 |
SH2D3C | SH2D3C | Q8N5H7 | SH2 domain-containing protein 3C | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 110 | 440 | 72 | 72 | 0 |
SIRT2 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 56 | 85 | 17 | 17 | 0 |
SIRT6 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | Not Cancer Driver | No | 1 | hippie | 33 | 164 | 12 | 12 | 0 |
SKP2 | SKP2 | Q13309 | S-phase kinase-associated protein 2 | chr5 | Not Cancer Driver | No | 3 | hippie, biogrid | 52 | 52 | 6 | 6 | 0 |
SLC25A51_ENST00000242275 | SLC25A51 | Q9H1U9 | Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 21 | 0 | 0 | 0 |
SOSTDC1 | SOSTDC1 | Q6X4U4 | Sclerostin domain-containing protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 22 | 72 | 3 | 3 | 0 |
SPATC1 | SPATC1 | Q76KD6 | Speriolin | chr8 | Not Cancer Driver | No | 1 | hippie | 90 | 380 | 57 | 57 | 0 |
SPINT2 | SPINT2 | O43291 | Kunitz-type protease inhibitor 2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 25 | 3 | 3 | 1 |
SPOP | SPOP | O43791 | Speckle-type POZ protein | chr17 | Census, Compendium | Yes | 1 | hippie | 147 | 25 | 5 | 5 | 6 |
SSSCA1 | ZNRD2 | O60232 | Protein ZNRD2 | chr11 | Not Cancer Driver | No | 1 | intact | 19 | 103 | 12 | 12 | 0 |
STAU1 | STAU1 | O95793 | Double-stranded RNA-binding protein Staufen homolog 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 77 | 456 | 63 | 63 | 0 |
SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 10 | 76 | 7 | 7 | 0 |
TAS2R13 | TAS2R13 | Q9NYV9 | Taste receptor type 2 member 13 | chr12 | Not Cancer Driver | No | 1 | hippie | 33 | 0 | 0 | 0 | 0 |
TBK1 | TBK1 | Q9UHD2 | Serine/threonine-protein kinase TBK1 | chr12 | Not Cancer Driver | No | 1 | hippie | 101 | 42 | 5 | 5 | 12 |
TCP1 | TCP1 | P17987 | T-complex protein 1 subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie | 54 | 55 | 10 | 10 | 0 |
TFDP1 | TFDP1 | Q14186 | Transcription factor Dp-1 | chr13 | Not Cancer Driver | No | 1 | hippie | 82 | 245 | 47 | 47 | 0 |
TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | Not Cancer Driver | No | 1 | hippie | 41 | 41 | 4 | 4 | 10 |
TGFBR1_ENST00000374994 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | Not Cancer Driver | No | 1 | hippie | 86 | 23 | 3 | 3 | 15 |
TK1 | TK1 | P04183 | Thymidine kinase, cytosolic | chr17 | Not Cancer Driver | No | 1 | hippie | 26 | 13 | 4 | 4 | 0 |
TNIP2 | TNIP2 | Q8NFZ5 | TNFAIP3-interacting protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 43 | 316 | 36 | 36 | 0 |
TP63 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | Census, Compendium | Yes | 1 | hippie | 229 | 398 | 143 | 143 | 28 |
TP73 | TP73 | O15350 | Tumor protein p73 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 82 | 443 | 55 | 55 | 0 |
TPR | TPR | P12270 | Nucleoprotein TPR | chr1 | Census | Yes | 1 | intact, hippie | 311 | 1990 | 266 | 266 | 0 |
TRIM33 | TRIM33 | Q9UPN9 | E3 ubiquitin-protein ligase TRIM33 | chr1 | Census, Compendium | Yes | 1 | hippie | 110 | 617 | 51 | 51 | 0 |
TRIP13 | TRIP13 | Q15645 | Pachytene checkpoint protein 2 homolog | chr5 | Not Cancer Driver | No | 2 | intact, hippie | 62 | 30 | 6 | 6 | 1 |
TRRAP | TRRAP | Q9Y4A5 | Transformation/transcription domain-associated protein | chr7 | Census, Compendium | Yes | 1 | hippie | 554 | 402 | 59 | 59 | 8 |
TTK | TTK | P33981 | Dual specificity protein kinase TTK | chr6 | Not Cancer Driver | No | 1 | hippie | 136 | 352 | 46 | 46 | 0 |
TUBA1A | TUBA1A | Q71U36 | Tubulin alpha-1A chain | chr12 | Not Cancer Driver | No | 1 | hippie | 59 | 52 | 11 | 11 | 8 |
TUBA1C_ENST00000301072 | TUBA1C | Q9BQE3 | Tubulin alpha-1C chain | chr12 | Not Cancer Driver | No | 1 | hippie | 39 | 50 | 5 | 5 | 0 |
TUBA4A | TUBA4A | P68366 | Tubulin alpha-4A chain | chr2 | Not Cancer Driver | No | 1 | hippie | 73 | 39 | 4 | 4 | 5 |
TUBB | TUBB | P07437 | Tubulin beta chain | chr6 | Not Cancer Driver | No | 1 | hippie | 40 | 63 | 11 | 11 | 5 |
TUBB2A | TUBB2A | Q13885 | Tubulin beta-2A chain | chr6 | Not Cancer Driver | No | 1 | hippie | 44 | 70 | 13 | 13 | 2 |
TUBB4B | TUBB4B | P68371 | Tubulin beta-4B chain | chr9 | Not Cancer Driver | No | 1 | hippie | 52 | 65 | 11 | 11 | 2 |
TUBG1 | TUBG1 | P23258 | Tubulin gamma-1 chain | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 44 | 10 | 10 | 3 |
UBB_ENST00000614404 | UBB | P0CG47 | Polyubiquitin-B | chr17 | Not Cancer Driver | No | 1 | hippie | 20 | 102 | 8 | 8 | 0 |
UBE2C | UBE2C | O00762 | Ubiquitin-conjugating enzyme E2 C | chr20 | Not Cancer Driver | No | 1 | hippie | 13 | 40 | 0 | 0 | 0 |
UBE2D2 | UBE2D2 | P62837 | Ubiquitin-conjugating enzyme E2 D2 | chr5 | Compendium | Yes | 1 | hippie | 19 | 13 | 1 | 1 | 0 |
UBE2S | UBE2S | Q16763 | Ubiquitin-conjugating enzyme E2 S | chr19 | Not Cancer Driver | No | 1 | hippie | 25 | 102 | 12 | 12 | 0 |
UBR5 | UBR5 | O95071 | E3 ubiquitin-protein ligase UBR5 | chr8 | Census, Compendium | Yes | 1 | hippie | 340 | 1296 | 162 | 162 | 0 |
USP22 | USP22 | Q9UPT9 | Ubiquitin carboxyl-terminal hydrolase 22 | chr17 | Not Cancer Driver | No | 1 | hippie | 64 | 50 | 1 | 1 | 0 |
USP37_ENST00000454775 | USP37 | Q86T82 | Ubiquitin carboxyl-terminal hydrolase 37 | chr2 | Not Cancer Driver | No | 1 | hippie | 112 | 530 | 62 | 62 | 0 |
WDR5 | WDR5 | P61964 | WD repeat-containing protein 5 | chr9 | Not Cancer Driver | No | 1 | hippie | 30 | 35 | 3 | 3 | 0 |
XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie | 140 | 33 | 9 | 9 | 0 |
YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | Not Cancer Driver | No | 1 | hippie | 51 | 489 | 49 | 49 | 0 |
YARS2 | YARS2 | Q9Y2Z4 | Tyrosine--tRNA ligase, mitochondrial | chr12 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 59 | 62 | 11 | 11 | 2 |
YBX1 | YBX1 | P67809 | Y-box-binding protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 41 | 312 | 41 | 41 | 0 |
ZWINT | ZWINT | O95229 | ZW10 interactor | chr10 | Not Cancer Driver | No | 1 | hippie | 65 | 168 | 44 | 44 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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