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CD247 ,CD247 ,P20963
  • Uniprot Accession= P20963
  • Ensembl Transcript= ENST00000362089.9
  • Uniprot Name= CD247
  • Name= T-cell surface glycoprotein CD3 zeta chain
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 3
  • Number of Interaction partner in hippie: 125
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AC104662.2 PI4K2B G5E9Z4 Phosphatidylinositol 4-kinase type 2 chr4 Not Cancer Driver No 1 hippie 48 0 0 0 0
ACACB_ENST00000377848 ACACB O00763 Acetyl-CoA carboxylase 2 chr12 Not Cancer Driver No 1 hippie 388 342 62 62 0
ACE ACE P12821 Angiotensin-converting enzyme chr17 Not Cancer Driver No 1 hippie 201 86 8 8 0
ACOT7 ACOT7 O00154 Cytosolic acyl coenzyme A thioester hydrolase chr1 Not Cancer Driver No 1 hippie 43 77 16 16 0
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 hippie 70 48 14 14 84
AHSA1 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 1 hippie 46 146 17 17 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 Not Cancer Driver No 1 hippie 49 154 13 13 0
ATAD2 ATAD2 Q6PL18 ATPase family AAA domain-containing protein 2 chr8 Not Cancer Driver No 1 hippie 227 647 113 113 0
ATXN2_ENST00000550104 ATXN2 Q99700 Ataxin-2 chr12 Not Cancer Driver No 1 hippie 146 1228 134 134 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 hippie 65 334 38 38 0
CARMIL2 CARMIL2 Q6F5E8 Capping protein, Arp2/3 and myosin-I linker protein 2 chr16 Not Cancer Driver No 1 hippie 154 669 75 75 4
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 hippie 115 512 56 56 4
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 Census, Compendium Yes 1 hippie 50 0 0 0 0
CD2 CD2 P06729 T-cell surface antigen CD2 chr1 Not Cancer Driver No 1 hippie 75 126 35 35 0
CD244 CD244 Q9BZW8 Natural killer cell receptor 2B4 chr1 Not Cancer Driver No 1 hippie 77 92 22 22 0
CD247 CD247 P20963 T-cell surface glycoprotein CD3 zeta chain chr1 Not Cancer Driver No 1 hippie 33 91 24 24 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 Census Yes 1 hippie 42 18 10 10 0
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 Not Cancer Driver No 1 hippie 54 3 1 1 0
CD3D CD3D P04234 T-cell surface glycoprotein CD3 delta chain chr11 Not Cancer Driver No 1 hippie 23 2 1 1 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 Not Cancer Driver No 1 hippie 28 72 12 12 0
CD48_ENST00000368046 CD48 P09326 CD48 antigen chr1 Not Cancer Driver No 1 hippie 39 2 0 0 0
CD5 CD5 P06127 T-cell surface glycoprotein CD5 chr11 Not Cancer Driver No 1 hippie 67 146 19 19 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 Not Cancer Driver No 1 hippie 40 44 2 2 0
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie 190 71 6 6 1
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 Census, Compendium Yes 1 hippie, biogrid 247 1212 214 214 148
CPD CPD O75976 Carboxypeptidase D chr17 Not Cancer Driver No 1 hippie 131 476 45 45 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 Not Cancer Driver No 1 hippie 41 18 1 1 0
CZIB CZIB Q9NWV4 CXXC motif containing zinc binding protein chr1 Not Cancer Driver No 1 hippie 19 2 1 1 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 Compendium Yes 1 hippie 182 331 42 42 0
DNAJA2 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 hippie 50 174 27 27 0
DNASE1L3 DNASE1L3 Q13609 Deoxyribonuclease gamma chr3 Not Cancer Driver No 1 hippie 43 15 4 4 0
DOCK2 DOCK2 Q92608 Dedicator of cytokinesis protein 2 chr5 Not Cancer Driver No 1 hippie 480 266 79 79 2
EEF1G EEF1G P26641 Elongation factor 1-gamma chr11 Not Cancer Driver No 1 hippie 44 66 5 5 0
EIF3F_ENST00000309828 EIF3F O00303 Eukaryotic translation initiation factor 3 subunit F chr11 Not Cancer Driver No 1 hippie 29 125 8 8 1
EIF3M EIF3M Q7L2H7 Eukaryotic translation initiation factor 3 subunit M chr11 Not Cancer Driver No 1 hippie 44 0 0 0 0
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 Not Cancer Driver No 1 hippie 37 21 5 5 5
ERICH6B ERICH6B Q5W0A0 Glutamate-rich protein 6B chr13 Not Cancer Driver No 1 hippie 152 323 125 125 0
ESYT1_ENST00000394048 ESYT1 Q9BSJ8 Extended synaptotagmin-1 chr12 Not Cancer Driver No 1 hippie 126 278 32 32 0
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 1 hippie 94 646 93 93 0
FCGR3A_ENST00000443193 FCGR3A P08637 Low affinity immunoglobulin gamma Fc region receptor III-A chr1 Not Cancer Driver No 1 hippie 69 0 0 0 1
FLNB_ENST00000295956 FLNB O75369 Filamin-B chr3 Not Cancer Driver No 1 hippie 362 1183 170 170 19
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 Not Cancer Driver No 1 hippie 85 537 73 73 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 Compendium Yes 1 hippie 50 24 0 0 0
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 Census Yes 1 hippie, biogrid 56 263 34 34 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
GRWD1 GRWD1 Q9BQ67 Glutamate-rich WD repeat-containing protein 1 chr19 Not Cancer Driver No 1 hippie 44 187 14 14 0
HERC1 HERC1 Q15751 Probable E3 ubiquitin-protein ligase HERC1 chr15 Not Cancer Driver No 1 hippie, biogrid 487 1344 129 129 1
HIVEP1 HIVEP1 P15822 Zinc finger protein 40 chr6 Not Cancer Driver No 1 hippie 344 2238 292 292 0
HNRNPA3 HNRNPA3 P51991 Heterogeneous nuclear ribonucleoprotein A3 chr2 Not Cancer Driver No 1 hippie 46 285 37 37 0
HNRNPAB HNRNPAB Q99729 Heterogeneous nuclear ribonucleoprotein A/B chr5 Not Cancer Driver No 1 hippie 31 202 11 11 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 hippie 77 504 45 45 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie 100 254 43 43 0
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 Census, Compendium Yes 1 hippie 167 63 10 10 7
KIAA0408 KIAA0408 Q6ZU52 Uncharacterized protein KIAA0408 chr6 Not Cancer Driver No 1 hippie 112 607 94 94 0
LARP1 LARP1 Q6PKG0-3 Isoform 2 of La-related protein 1 chr5 Not Cancer Driver No 1 hippie 136 726 100 100 0
LAT_ENST00000360872 LAT O43561 Linker for activation of T-cells family member 1 chr16 Not Cancer Driver No 1 hippie 37 213 29 29 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 86 94 13 13 1
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 131 18 2 2 1
LRRFIP2 LRRFIP2 Q9Y608 Leucine-rich repeat flightless-interacting protein 2 chr3 Not Cancer Driver No 1 hippie 75 584 62 62 0
LY6E_ENST00000522024 LY6E Q16553 Lymphocyte antigen 6E chr8 Not Cancer Driver No 1 hippie 13 0 0 0 0
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 Not Cancer Driver No 1 hippie 101 128 22 22 0
MPRIP_ENST00000341712 MPRIP Q6WCQ1 Myosin phosphatase Rho-interacting protein chr17 Not Cancer Driver No 1 hippie 118 735 95 95 0
MYH4 MYH4 Q9Y623 Myosin-4 chr17 Not Cancer Driver No 1 hippie 464 1138 288 288 0
MYO1G MYO1G B0I1T2 Unconventional myosin-Ig chr7 Not Cancer Driver No 1 hippie 125 117 12 12 0
NAP1L1 NAP1L1 P55209 Nucleosome assembly protein 1-like 1 chr12 Not Cancer Driver No 1 hippie 47 207 31 31 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 1 hippie 48 111 17 17 0
NCR1 NCR1 O76036 Natural cytotoxicity triggering receptor 1 chr19 Not Cancer Driver No 1 hippie 81 27 8 8 0
NCR3 NCR3 O14931 Natural cytotoxicity triggering receptor 3 chr6 Not Cancer Driver No 1 hippie 26 31 2 2 0
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 Not Cancer Driver No 1 hippie 214 248 61 61 4
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 29 249 22 22 0
NSF NSF P46459 Vesicle-fusing ATPase chr17 Not Cancer Driver No 1 hippie 47 84 3 3 2
NUP205 NUP205 Q92621 Nuclear pore complex protein Nup205 chr7 Not Cancer Driver No 1 hippie 251 101 16 16 1
PCBP2_ENST00000439930 PCBP2 Q15366 Poly(rC)-binding protein 2 chr12 Not Cancer Driver No 1 hippie 40 200 24 24 0
PI4K2B PI4K2B Q8TCG2 Phosphatidylinositol 4-kinase type 2-beta chr4 Not Cancer Driver No 1 hippie 51 99 4 4 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 hippie 154 268 61 61 2
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 Census, Compendium Yes 1 hippie 179 214 31 31 2
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 Not Cancer Driver No 1 hippie 11 24 3 3 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 hippie 26 23 4 4 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 Not Cancer Driver No 1 hippie 141 364 62 62 4
PTPN3 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 Not Cancer Driver No 1 hippie 139 214 28 28 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 Census, Compendium Yes 1 hippie 73 192 25 25 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 Census, Compendium Yes 1 hippie 315 462 107 107 0
PWP2 PWP2 Q15269 Periodic tryptophan protein 2 homolog chr21 Not Cancer Driver No 1 hippie 99 101 9 9 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie 24 50 4 4 0
RALYL_ENST00000521268 RALYL Q86SE5 RNA-binding Raly-like protein chr8 Not Cancer Driver No 1 hippie 111 181 75 75 0
RCN2_ENST00000394885 RCN2 Q14257 Reticulocalbin-2 chr15 Not Cancer Driver No 1 hippie 35 125 11 11 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 Not Cancer Driver No 1 hippie 58 50 8 8 0
RIC1 RIC1 Q4ADV7 Guanine nucleotide exchange factor subunit RIC1 chr9 Not Cancer Driver No 1 hippie 159 252 15 15 1
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 Not Cancer Driver No 1 hippie 44 33 2 2 0
RPL6 RPL6 Q02878 60S ribosomal protein L6 chr12 Not Cancer Driver No 1 hippie 41 159 24 24 0
RPL7A RPL7A P62424 60S ribosomal protein L7a chr9 Not Cancer Driver No 1 hippie 27 100 5 5 0
RPL8_ENST00000528957 RPL8 P62917 60S ribosomal protein L8 chr8 Not Cancer Driver No 1 hippie 32 115 17 17 0
RPS24_ENST00000613865 RPS24 P62847 40S ribosomal protein S24 chr10 Not Cancer Driver No 1 hippie 13 88 10 10 0
RPS26_ENST00000646449 RPS26 P62854 40S ribosomal protein S26 chr12 Not Cancer Driver No 1 hippie 9 52 5 5 2
RTL9_ENST00000540313 RTL9 Q8NET4 Retrotransposon Gag-like protein 9 chrX Not Cancer Driver No 1 hippie 256 1222 220 220 0
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 Census, Compendium Yes 1 hippie 48 333 19 19 0
SH2D1A SH2D1A O60880 SH2 domain-containing protein 1A chrX Not Cancer Driver No 1 hippie 40 24 8 8 19
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie 84 397 58 58 0
SHC3 SHC3 Q92529 SHC-transforming protein 3 chr9 Not Cancer Driver No 1 hippie 94 432 64 64 0
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 Not Cancer Driver No 1 hippie 80 330 30 30 3
SKOR1_ENST00000380035 SKOR1 P84550 SKI family transcriptional corepressor 1 chr15 Not Cancer Driver No 1 hippie 104 682 47 47 0
SLA2 SLA2 Q9H6Q3 Src-like-adapter 2 chr20 Not Cancer Driver No 1 hippie 32 43 9 9 0
SLA_ENST00000338087 SLA Q13239 Src-like-adapter chr8 Not Cancer Driver No 1 hippie 59 51 11 11 0
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 1 hippie 41 0 0 0 0
SPG11 SPG11 Q96JI7 Spatacsin chr15 Not Cancer Driver No 1 hippie 252 126 12 12 1
STAT5A_ENST00000590949 STAT5A P42229 Signal transducer and activator of transcription 5A chr17 Not Cancer Driver No 1 hippie 89 125 14 14 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 Census, Compendium Yes 1 hippie 93 144 19 19 5
STRBP_ENST00000348403 STRBP Q96SI9 Spermatid perinuclear RNA-binding protein chr9 Not Cancer Driver No 1 hippie 74 306 31 31 0
SUCLG2_ENST00000307227 SUCLG2 Q96I99 Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial chr3 Not Cancer Driver No 1 hippie 48 12 2 2 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 Census Yes 1 hippie 89 80 6 6 1
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 Not Cancer Driver No 1 hippie 28 80 6 6 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 Not Cancer Driver No 1 hippie 16 3 0 0 0
TMF1 TMF1 P82094 TATA element modulatory factor chr3 Not Cancer Driver No 1 hippie 109 946 99 99 0
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 Not Cancer Driver No 1 hippie 33 234 29 29 8
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 Not Cancer Driver No 1 hippie 86 129 67 67 0
TUBA1B TUBA1B P68363 Tubulin alpha-1B chain chr12 Not Cancer Driver No 1 hippie 41 52 9 9 0
UBASH3A UBASH3A P57075 Ubiquitin-associated and SH3 domain-containing protein A chr21 Not Cancer Driver No 1 hippie 101 27 8 8 0
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 Not Cancer Driver No 1 hippie 20 89 4 4 1
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VTN VTN P04004 Vitronectin chr17 Not Cancer Driver No 1 hippie 76 168 29 29 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 Not Cancer Driver No 2 intact, hippie 126 117 17 17 8
ZNF281_ENST00000367353 ZNF281 Q9Y2X9 Zinc finger protein 281 chr1 Not Cancer Driver No 1 hippie 92 709 67 67 0
ZNF439 ZNF439 Q8NDP4 Zinc finger protein 439 chr19 Not Cancer Driver No 1 hippie 81 132 19 19 0