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CCT3 ,CCT3 ,P49368
  • Number of Interaction partner in intact: 198
  • Number of Interaction partner in biogrid: 211
  • Number of Interaction partner in hippie: 506
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ABHD17A_ENST00000292577 ABHD17A Q96GS6 Alpha/beta hydrolase domain-containing protein 17A chr19 Not Cancer Driver No 1 hippie, biogrid 35 20 5 5 0
AC104662.2 PI4K2B G5E9Z4 Phosphatidylinositol 4-kinase type 2 chr4 Not Cancer Driver No 1 intact, hippie 48 0 0 0 0
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 intact 70 48 14 14 84
ACTBL2 ACTBL2 Q562R1 Beta-actin-like protein 2 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 73 29 5 5 0
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ACTL6A ACTL6A O96019 Actin-like protein 6A chr3 Not Cancer Driver No 2 hippie, biogrid 61 74 15 15 0
ACTR1A ACTR1A P61163 Alpha-centractin chr10 Not Cancer Driver No 2 hippie, biogrid 47 14 0 0 0
ACTR1B ACTR1B P42025 Beta-centractin chr2 Not Cancer Driver No 3 intact, hippie, biogrid 59 17 4 4 0
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 51 6 2 2 0
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 32 16 2 2 0
ACTR3B ACTR3B Q9P1U1 Actin-related protein 3B chr7 Not Cancer Driver No 2 intact, hippie, biogrid 55 5 0 0 0
ACTRT1 ACTRT1 Q8TDG2 Actin-related protein T1 chrX Not Cancer Driver No 1 hippie, biogrid 153 10 7 7 0
ACTRT2 ACTRT2 Q8TDY3 Actin-related protein T2 chr1 Not Cancer Driver No 1 hippie, biogrid 97 33 7 7 0
AGBL4 AGBL4 Q5VU57 Cytosolic carboxypeptidase 6 chr1 Not Cancer Driver No 1 hippie, biogrid 65 72 2 2 0
AGO3 AGO3 Q9H9G7 Protein argonaute-3 chr1 Not Cancer Driver No 1 intact, hippie 110 143 19 19 0
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
AHSA1 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 1 hippie 46 146 17 17 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 intact, hippie 108 158 24 24 4
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 Not Cancer Driver No 1 hippie 173 788 103 103 0
ANG ANG P03950 Angiogenin chr14 Not Cancer Driver No 1 hippie 19 36 2 2 14
ANGPTL7 ANGPTL7 O43827 Angiopoietin-related protein 7 chr1 Not Cancer Driver No 1 hippie, biogrid 38 33 7 7 0
ANK3 ANK3 Q12955 Ankyrin-3 chr10 Not Cancer Driver No 1 hippie 860 3054 579 579 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 intact, hippie 84 181 32 32 0
ARF1_ENST00000272102 ARF1 P84077 ADP-ribosylation factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 30 4 2 2 2
ARMC6 ARMC6 Q6NXE6 Armadillo repeat-containing protein 6 chr19 Not Cancer Driver No 1 intact, hippie 65 77 5 5 0
ART3 ART3 Q13508 Ecto-ADP-ribosyltransferase 3 chr4 Not Cancer Driver No 1 intact 54 82 12 12 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 Not Cancer Driver No 1 intact, hippie 65 451 58 58 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
ATP6V1B1 ATP6V1B1 P15313 V-type proton ATPase subunit B, kidney isoform chr2 Not Cancer Driver No 1 hippie, biogrid 77 66 14 14 9
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie 51 63 8 8 0
B9D1 B9D1 Q9UPM9 B9 domain-containing protein 1 chr17 Not Cancer Driver No 1 intact, hippie 16 51 6 6 2
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 biogrid 29 195 9 9 0
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 hippie 37 63 7 7 0
BBS10 BBS10 Q8TAM1 Bardet-Biedl syndrome 10 protein chr12 Not Cancer Driver No 1 intact, hippie 78 67 11 11 24
BBS12 BBS12 Q6ZW61 Bardet-Biedl syndrome 12 protein chr4 Not Cancer Driver No 1 intact, hippie 88 34 5 5 10
BBS7 BBS7 Q8IWZ6 Bardet-Biedl syndrome 7 protein chr4 Not Cancer Driver No 1 intact, hippie 99 56 8 8 4
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 Not Cancer Driver No 1 intact, hippie, biogrid 94 75 21 21 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 2 intact, hippie 50 150 30 30 0
BMX_ENST00000342014 BMX P51813 Cytoplasmic tyrosine-protein kinase BMX chrX Not Cancer Driver No 1 hippie 106 172 27 27 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 80 45 4 4 0
BUB3 BUB3 O43684 Mitotic checkpoint protein BUB3 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 46 60 6 6 0
BUD31 BUD31 P41223 Protein BUD31 homolog chr7 Not Cancer Driver No 1 intact, hippie 20 32 4 4 0
C11orf54_ENST00000354421 C11orf54 Q9H0W9 Ester hydrolase C11orf54 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 23 23 0 0 0
C1orf127 C1orf127 G8JLG8 Uncharacterized protein C1orf127 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 105 442 72 72 0
CAD CAD P27708 CAD protein chr2 Not Cancer Driver No 1 hippie, biogrid 287 368 52 52 1
CAMKMT CAMKMT Q7Z624 Calmodulin-lysine N-methyltransferase chr2 Not Cancer Driver No 1 hippie, biogrid 34 31 0 0 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 hippie, biogrid 65 334 38 38 0
CBX1_ENST00000225603 CBX1 P83916 Chromobox protein homolog 1 chr17 Not Cancer Driver No 1 intact, hippie 31 154 25 25 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CCL1 CCL1 P22362 C-C motif chemokine 1 chr17 Not Cancer Driver No 1 intact 27 0 0 0 0
CCNC CCNC P24863 Cyclin-C chr6 Census Yes 1 intact, hippie 32 33 3 3 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 Census, Compendium Yes 1 hippie 55 31 25 25 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 Not Cancer Driver No 6 intact, hippie, biogrid 63 46 3 3 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 Not Cancer Driver No 6 intact, hippie, biogrid 51 92 2 2 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 5 intact, hippie, biogrid 83 72 10 10 1
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 Not Cancer Driver No 6 intact, hippie, biogrid 66 5 1 1 0
CCT6B CCT6B Q92526 T-complex protein 1 subunit zeta-2 chr17 Not Cancer Driver No 4 intact, hippie, biogrid 90 1 0 0 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 7 intact, hippie, biogrid 59 36 6 6 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 Not Cancer Driver No 6 intact, hippie, biogrid 41 36 2 2 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 Not Cancer Driver No 3 intact, hippie, biogrid 44 198 15 15 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 100 618 77 77 0
CDC73 CDC73 Q6P1J9 Parafibromin chr1 Census, Compendium Yes 1 hippie 110 210 39 39 2
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 intact 150 400 82 82 5
CDK11A CDK11A Q9UQ88 Cyclin-dependent kinase 11A chr1 Not Cancer Driver No 1 hippie, biogrid 66 485 44 44 0
CDK13 CDK13 Q14004 Cyclin-dependent kinase 13 chr7 Not Cancer Driver No 1 intact, hippie 155 1138 99 99 6
CDK18_ENST00000360066 CDK18 Q07002 Cyclin-dependent kinase 18 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 64 132 17 17 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 Census, Compendium Yes 1 hippie 52 52 5 5 3
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 Not Cancer Driver No 3 intact, hippie, biogrid 48 5 1 1 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie, biogrid 50 34 2 2 0
CELA2B CELA2B P08218 Chymotrypsin-like elastase family member 2B chr1 Not Cancer Driver No 1 hippie, biogrid 40 3 0 0 0
CERCAM CERCAM Q5T4B2 Inactive glycosyltransferase 25 family member 3 chr9 Not Cancer Driver No 1 hippie, biogrid 107 68 17 17 0
CETN2 CETN2 P41208 Centrin-2 chrX Not Cancer Driver No 1 intact, hippie 33 97 11 11 0
CFAP300 CFAP300 Q9BRQ4 Cilia- and flagella-associated protein 300 chr11 Not Cancer Driver No 1 intact, hippie 36 0 0 0 1
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 3 intact, hippie 287 145 18 18 151
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie, biogrid 190 71 6 6 1
COP1 COP1 Q8NHY2 E3 ubiquitin-protein ligase COP1 chr1 Not Cancer Driver No 2 intact, hippie 106 147 11 11 0
COPA_ENST00000241704 COPA P53621 Coatomer subunit alpha chr1 Not Cancer Driver No 1 hippie 163 157 18 18 4
CSAG1 CSAG1 Q6PB30 Putative chondrosarcoma-associated gene 1 protein chrX Not Cancer Driver No 1 intact, hippie 32 70 28 28 0
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 Not Cancer Driver No 1 hippie 62 133 18 18 0
CTTNBP2 CTTNBP2 Q8WZ74 Cortactin-binding protein 2 chr7 Not Cancer Driver No 1 intact, hippie 247 864 137 137 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
CYP27A1 CYP27A1 Q02318 Sterol 26-hydroxylase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 69 47 11 11 7
DAZ2_ENST00000382424 DAZ2 Q13117 Deleted in azoospermia protein 2 chrY Not Cancer Driver No 1 hippie, biogrid 1 72 0 0 0
DCAF10 DCAF10 Q5QP82 DDB1- and CUL4-associated factor 10 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 50 201 11 11 0
DCAF11 DCAF11 Q8TEB1 DDB1- and CUL4-associated factor 11 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 89 149 25 25 0
DCAF12 DCAF12 Q5T6F0 DDB1- and CUL4-associated factor 12 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 59 70 7 7 0
DCAF12L2 DCAF12L2 Q5VW00 DDB1- and CUL4-associated factor 12-like protein 2 chrX Census, Compendium Yes 1 intact, hippie, biogrid 227 98 51 51 0
DCAF13_ENST00000612750 DCAF13 Q9NV06 DDB1- and CUL4-associated factor 13 chr8 Not Cancer Driver No 2 hippie, biogrid 85 101 18 18 0
DCAF4 DCAF4 Q8WV16 DDB1- and CUL4-associated factor 4 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 59 114 11 11 0
DCAF4L1 DCAF4L1 Q3SXM0 DDB1- and CUL4-associated factor 4-like protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 88 0 0 0 0
DCAF5 DCAF5 Q96JK2 DDB1- and CUL4-associated factor 5 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 119 521 80 80 0
DCAF7 DCAF7 P61962 DDB1- and CUL4-associated factor 7 chr17 Not Cancer Driver No 4 intact, hippie, biogrid 48 0 0 0 0
DCAF8 DCAF8 Q5TAQ9 DDB1- and CUL4-associated factor 8 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 85 273 55 55 1
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 Not Cancer Driver No 1 intact 57 167 24 24 0
DDB2 DDB2 Q92466 DNA damage-binding protein 2 chr11 Census, Compendium Yes 2 hippie, biogrid 45 70 5 5 2
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DEPDC5_ENST00000382112 DEPDC5 O75140 GATOR complex protein DEPDC5 chr22 Not Cancer Driver No 1 hippie 226 575 91 91 7
DIPK2A DIPK2A Q8NDZ4 Divergent protein kinase domain 2A chr3 Not Cancer Driver No 1 intact, hippie 56 9 0 0 0
DNAI2 DNAI2 Q9GZS0 Dynein axonemal intermediate chain 2 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 136 209 47 47 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 hippie, biogrid 37 153 16 16 0
DNAJA4_ENST00000394852 DNAJA4 Q8WW22 DnaJ homolog subfamily A member 4 chr15 Not Cancer Driver No 1 hippie, biogrid 43 110 6 6 0
DNAJC13 DNAJC13 O75165 DnaJ homolog subfamily C member 13 chr3 Not Cancer Driver No 1 intact, hippie 276 141 17 17 0
DNAJC7 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 Not Cancer Driver No 1 intact, hippie 41 102 9 9 0
DOCK5 DOCK5 Q9H7D0 Dedicator of cytokinesis protein 5 chr8 Not Cancer Driver No 1 intact, hippie 278 330 45 45 0
DPH1 DPH1 Q9BZG8 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 chr17 Not Cancer Driver No 1 intact 41 67 8 8 2
DTL DTL Q9NZJ0 Denticleless protein homolog chr1 Not Cancer Driver No 2 hippie, biogrid 73 331 49 49 0
DYNC1I2_ENST00000409773 DYNC1I2 Q13409 Cytoplasmic dynein 1 intermediate chain 2 chr2 Not Cancer Driver No 1 hippie, biogrid 82 300 42 42 1
EED_ENST00000263360 EED O75530 Polycomb protein EED chr11 Census Yes 2 intact, hippie 64 79 11 11 6
EEF1AKMT3 EEF1AKMT3 Q96AZ1 EEF1A lysine methyltransferase 3 chr12 Not Cancer Driver No 1 hippie 23 33 1 1 0
EEF1G EEF1G P26641 Elongation factor 1-gamma chr11 Not Cancer Driver No 1 hippie 44 66 5 5 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EHD2 EHD2 Q9NZN4 EH domain-containing protein 2 chr19 Compendium Yes 1 hippie, biogrid 85 125 12 12 0
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 Not Cancer Driver No 1 hippie 142 585 71 71 0
EIF2B2 EIF2B2 P49770 Translation initiation factor eIF-2B subunit beta chr14 Not Cancer Driver No 1 hippie, biogrid 40 83 11 11 9
EIF6_ENST00000374436 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 Not Cancer Driver No 1 hippie, biogrid 30 17 3 3 0
EIPR1_ENST00000382125 EIPR1 Q53HC9 EARP and GARP complex-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 52 71 4 4 0
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 intact 51 21 2 2 0
EPB41L4A_ENST00000621003 EPB41L4A Q9HCS5 Band 4.1-like protein 4A chr5 Not Cancer Driver No 1 hippie, biogrid 119 378 65 65 0
EPS15 EPS15 P42566 Epidermal growth factor receptor substrate 15 chr1 Census, Compendium Yes 1 hippie 106 543 66 66 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
ERCC8 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 Not Cancer Driver No 1 hippie 25 53 8 8 7
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 Not Cancer Driver No 1 intact, hippie 55 297 37 37 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 intact, hippie 90 92 11 11 1
ETFA ETFA P13804 Electron transfer flavoprotein subunit alpha, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 30 34 2 2 3
ETFBKMT_ENST00000412352 ETFBKMT Q8IXQ9 Electron transfer flavoprotein beta subunit lysine methyltransferase chr12 Not Cancer Driver No 1 hippie 25 0 0 0 0
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 hippie 83 241 34 34 0
FAM83F FAM83F Q8NEG4 Protein FAM83F chr22 Not Cancer Driver No 1 hippie, biogrid 65 255 27 27 0
FAM86B2 FAM86B2 P0C5J1 Putative protein N-methyltransferase FAM86B2 chr8 Not Cancer Driver No 1 hippie, biogrid 29 6 0 0 0
FANCA FANCA O15360 Fanconi anemia group A protein chr16 Census, Compendium Yes 1 hippie 160 154 15 15 27
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FBXW4 FBXW4 P57775 F-box/WD repeat-containing protein 4 chr10 Not Cancer Driver No 4 intact, hippie, biogrid 36 21 0 0 0
FBXW5 FBXW5 Q969U6 F-box/WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 64 74 10 10 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 68 120 4 4 0
FBXW9 FBXW9 Q5XUX1 F-box/WD repeat-containing protein 9 chr19 Not Cancer Driver No 1 hippie, biogrid 49 88 11 11 0
FGD5 FGD5 Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 chr3 Compendium Yes 1 hippie, biogrid 275 915 180 180 0
FGF11 FGF11 Q92914 Fibroblast growth factor 11 chr17 Not Cancer Driver No 1 hippie 20 68 5 5 0
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 Not Cancer Driver No 1 hippie 85 52 8 8 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
FNDC11_ENST00000370097 FNDC11 Q9BVV2 Fibronectin type III domain-containing protein 11 chr20 Not Cancer Driver No 1 hippie 49 37 7 7 0
FUS FUS P35637 RNA-binding protein FUS chr16 Census Yes 1 hippie 51 524 51 51 20
FYCO1 FYCO1 Q9BQS8 FYVE and coiled-coil domain-containing protein 1 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 181 892 106 106 1
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie, biogrid 92 70 13 13 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 11 2 1 1 0
GAN GAN Q9H2C0 Gigaxonin chr16 Not Cancer Driver No 1 hippie 74 33 6 6 19
GANAB_ENST00000356638 GANAB Q14697 Neutral alpha-glucosidase AB chr11 Not Cancer Driver No 2 hippie, biogrid 129 132 20 20 3
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 Not Cancer Driver No 1 hippie 74 38 5 5 171
GEMIN4 GEMIN4 P57678 Gem-associated protein 4 chr17 Not Cancer Driver No 1 intact, hippie 101 24 1 1 0
GNB1L GNB1L Q9BYB4 Guanine nucleotide-binding protein subunit beta-like protein 1 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 69 18 0 0 0
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 Not Cancer Driver No 1 hippie, biogrid 45 24 2 2 16
GNB2 GNB2 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 50 21 0 0 7
GNB5 GNB5 O14775 Guanine nucleotide-binding protein subunit beta-5 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 60 16 1 1 1
GPC1 GPC1 P35052 Glypican-1 chr2 Not Cancer Driver No 1 hippie 58 166 14 14 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
GRWD1 GRWD1 Q9BQ67 Glutamate-rich WD repeat-containing protein 1 chr19 Not Cancer Driver No 1 hippie 44 187 14 14 0
GTF2I GTF2I P78347 General transcription factor II-I chr7 Compendium Yes 1 hippie, biogrid 74 365 27 27 0
HCFC2 HCFC2 Q9Y5Z7 Host cell factor 2 chr12 Not Cancer Driver No 2 hippie, biogrid 95 279 34 34 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 4 intact, hippie, biogrid 47 135 10 10 0
HDAC11 HDAC11 Q96DB2 Histone deacetylase 11 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 57 18 8 8 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 65 61 8 8 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 118 718 73 73 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX Not Cancer Driver No 1 hippie 178 409 59 59 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie 37 77 9 9 0
HIPK4 HIPK4 Q8NE63 Homeodomain-interacting protein kinase 4 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 87 258 23 23 0
HNRNPA0 HNRNPA0 Q13151 Heterogeneous nuclear ribonucleoprotein A0 chr5 Not Cancer Driver No 1 hippie 25 172 14 14 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie, biogrid 94 268 35 35 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
HSPE1 HSPE1 P61604 10 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 8 3 0 0 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 Not Cancer Driver No 1 hippie 61 251 28 28 0
IGBP1_ENST00000356413 IGBP1 P78318 Immunoglobulin-binding protein 1 chrX Not Cancer Driver No 2 intact, hippie 51 193 28 28 0
IGSF8_ENST00000614243 IGSF8 Q969P0 Immunoglobulin superfamily member 8 chr1 Not Cancer Driver No 1 hippie 93 207 32 32 0
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 intact, hippie 108 76 13 13 0
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 2 hippie, biogrid 45 71 9 9 0
INPPL1 INPPL1 O15357 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 chr11 Not Cancer Driver No 1 hippie 174 566 76 76 4
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX Compendium Yes 1 intact, hippie 71 337 39 39 0
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 Not Cancer Driver No 1 intact, hippie 43 253 19 19 1
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
ITFG1 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie 70 18 3 3 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 254 97 27 27 0
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 Census Yes 1 intact, hippie, biogrid 139 43 10 10 1
IVNS1ABP IVNS1ABP Q9Y6Y0 Influenza virus NS1A-binding protein chr1 Not Cancer Driver No 1 hippie 85 90 12 12 0
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 Census, Compendium Yes 1 hippie 167 63 10 10 7
JMJD4 JMJD4 Q9H9V9 2-oxoglutarate and iron-dependent oxygenase JMJD4 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 67 19 5 5 0
JMJD7 JMJD7 P0C870 Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 chr15 Not Cancer Driver No 1 hippie, biogrid 40 0 0 0 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 61 277 50 50 0
KDM4B KDM4B O94953 Lysine-specific demethylase 4B chr19 Not Cancer Driver No 3 intact, hippie, biogrid 133 429 49 49 3
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF21A KIF21A Q7Z4S6 Kinesin-like protein KIF21A chr12 Not Cancer Driver No 1 hippie 255 937 149 149 11
KLHDC2 KLHDC2 Q9Y2U9 Kelch domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 39 42 2 2 0
KLHDC8A KLHDC8A Q8IYD2 Kelch domain-containing protein 8A chr1 Not Cancer Driver No 2 intact, hippie, biogrid 60 3 4 4 0
KLHDC8B KLHDC8B Q8IXV7 Kelch domain-containing protein 8B chr3 Not Cancer Driver No 2 intact, hippie, biogrid 37 16 0 0 0
KLHL33 KLHL33 A6NCF5 Kelch-like protein 33 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 28 45 5 5 0
KLHL8 KLHL8 Q9P2G9 Kelch-like protein 8 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 75 63 7 7 0
KPNA4 KPNA4 O00629 Importin subunit alpha-3 chr3 Not Cancer Driver No 1 hippie, biogrid 59 112 12 12 0
KRT17 KRT17 Q04695 Keratin, type I cytoskeletal 17 chr17 Not Cancer Driver No 1 hippie 86 160 31 31 18
L1TD1 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie 149 534 114 114 0
L3MBTL2 L3MBTL2 Q969R5 Lethal(3)malignant brain tumor-like protein 2 chr22 Not Cancer Driver No 1 intact, hippie 95 210 38 38 0
LAMC1 LAMC1 P11047 Laminin subunit gamma-1 chr1 Not Cancer Driver No 1 hippie, biogrid 232 562 94 94 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 86 94 13 13 1
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie, biogrid 40 9 0 0 0
LDHB_ENST00000350669 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie, biogrid 47 15 2 2 11
LFNG LFNG Q8NES3 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe chr7 Not Cancer Driver No 1 hippie, biogrid 37 65 1 1 1
LGALS3 LGALS3 P17931 Galectin-3 chr14 Not Cancer Driver No 1 hippie 15 133 6 6 0
LGALS3BP LGALS3BP Q08380 Galectin-3-binding protein chr17 Not Cancer Driver No 1 hippie 62 9 0 0 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie 54 65 16 16 0
LNX2 LNX2 Q8N448 Ligand of Numb protein X 2 chr13 Not Cancer Driver No 1 intact, hippie 85 277 35 35 0
LOXL4 LOXL4 Q96JB6 Lysyl oxidase homolog 4 chr10 Not Cancer Driver No 1 hippie, biogrid 95 122 11 11 0
LRRC31 LRRC31 Q6UY01 Leucine-rich repeat-containing protein 31 chr3 Not Cancer Driver No 1 hippie 109 80 10 10 0
LRRC47 LRRC47 Q8N1G4 Leucine-rich repeat-containing protein 47 chr1 Not Cancer Driver No 1 hippie 65 291 30 30 0
LRRK1 LRRK1 Q38SD2 Leucine-rich repeat serine/threonine-protein kinase 1 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 289 261 33 33 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 2 intact, hippie 519 90 17 17 23
LSM1 LSM1 O15116 U6 snRNA-associated Sm-like protein LSm1 chr8 Not Cancer Driver No 1 intact 21 6 1 1 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 intact, hippie 10 17 1 1 0
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 Not Cancer Driver No 1 intact, hippie 40 85 10 10 0
MAP3K1 MAP3K1 Q13233 Mitogen-activated protein kinase kinase kinase 1 chr5 Census, Compendium Yes 1 hippie 184 820 62 62 3
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 74 355 44 44 0
MAP4K1 MAP4K1 Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 chr19 Not Cancer Driver No 1 hippie, biogrid 116 276 41 41 0
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 51 50 15 15 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 81 235 37 37 0
MAPK4 MAPK4 P31152 Mitogen-activated protein kinase 4 chr18 Not Cancer Driver No 1 intact, hippie, biogrid 111 222 42 42 0
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 79 165 20 20 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 Not Cancer Driver No 1 intact, hippie 64 94 9 9 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 2 intact, hippie 104 275 38 38 1
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 Not Cancer Driver No 1 hippie, biogrid 101 128 22 22 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MED29_ENST00000599213 MED29 Q9NX70 Mediator of RNA polymerase II transcription subunit 29 chr19 Not Cancer Driver No 1 intact, hippie 21 119 10 10 0
MED9 MED9 Q9NWA0 Mediator of RNA polymerase II transcription subunit 9 chr17 Not Cancer Driver No 1 intact, hippie 16 127 15 15 0
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie 76 446 42 42 0
METAP2 METAP2 P50579 Methionine aminopeptidase 2 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 54 176 19 19 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 Not Cancer Driver No 1 hippie 60 224 26 26 0
METTL18 METTL18 O95568 Histidine protein methyltransferase 1 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 37 125 8 8 0
METTL21C METTL21C Q5VZV1 Protein-lysine methyltransferase METTL21C chr13 Not Cancer Driver No 1 hippie, biogrid 54 47 13 13 0
METTL23_ENST00000341249 METTL23 Q86XA0 Histone-arginine methyltransferase METTL23 chr17 Not Cancer Driver No 1 hippie, biogrid 23 0 0 0 0
METTL27 METTL27 Q8N6F8 Methyltransferase-like protein 27 chr7 Not Cancer Driver No 1 hippie 36 47 8 8 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 Not Cancer Driver No 1 hippie 74 274 29 29 0
METTL6 METTL6 Q8TCB7 tRNA N(3)-methylcytidine methyltransferase METTL6 chr3 Not Cancer Driver No 1 hippie, biogrid 38 20 0 0 0
MIB2_ENST00000504599 MIB2 Q96AX9 E3 ubiquitin-protein ligase MIB2 chr1 Not Cancer Driver No 1 hippie, biogrid 88 307 31 31 0
MIPOL1 MIPOL1 Q8TD10 Mirror-image polydactyly gene 1 protein chr14 Not Cancer Driver No 2 intact, hippie 58 273 37 37 0
MKKS MKKS Q9NPJ1 McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin chr20 Not Cancer Driver No 1 hippie 56 6 1 1 22
MKS1 MKS1 Q9NXB0 Meckel syndrome type 1 protein chr17 Not Cancer Driver No 1 intact, hippie 82 152 23 23 2
MLST8_ENST00000397124 MLST8 Q9BVC4 Target of rapamycin complex subunit LST8 chr16 Not Cancer Driver No 2 hippie, biogrid 37 45 3 3 0
MMACHC MMACHC Q9Y4U1 Cyanocobalamin reductase / alkylcobalamin dealkylase chr1 Not Cancer Driver No 1 hippie, biogrid 29 85 5 5 14
MOB4 MOB4 Q9Y3A3 MOB-like protein phocein chr2 Not Cancer Driver No 1 intact, hippie 23 34 5 5 0
MOSPD2 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX Not Cancer Driver No 1 intact 58 143 16 16 0
MPPED1_ENST00000443721 MPPED1 O15442 Metallophosphoesterase domain-containing protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 79 26 15 15 0
MRPS5 MRPS5 P82675 28S ribosomal protein S5, mitochondrial chr2 Not Cancer Driver No 1 intact 52 157 20 20 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYH7B MYH7B A7E2Y1 Myosin-7B chr20 Not Cancer Driver No 1 hippie, biogrid 294 1103 138 138 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NCAPD3 NCAPD3 P42695 Condensin-2 complex subunit D3 chr11 Not Cancer Driver No 1 hippie 193 304 42 42 1
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 hippie 123 117 42 42 0
NEDD1_ENST00000266742 NEDD1 Q8NHV4 Protein NEDD1 chr12 Not Cancer Driver No 2 hippie, biogrid 87 282 36 36 0
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 1 intact, hippie 104 344 38 38 0
NFKB2 NFKB2 Q00653 Nuclear factor NF-kappa-B p100 subunit chr10 Census, Compendium Yes 1 intact, hippie 86 510 46 46 0
NFX1 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 Not Cancer Driver No 1 hippie 121 491 46 46 0
NGB NGB Q9NPG2 Neuroglobin chr14 Not Cancer Driver No 1 hippie 20 3 0 0 0
NIPSNAP1 NIPSNAP1 Q9BPW8 Protein NipSnap homolog 1 chr22 Not Cancer Driver No 1 intact, hippie 31 9 0 0 0
NME1_ENST00000393196 NME1 P15531 Nucleoside diphosphate kinase A chr17 Not Cancer Driver No 1 hippie 11 10 0 0 0
NOL10 NOL10 Q9BSC4 Nucleolar protein 10 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 52 182 22 22 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 Not Cancer Driver No 1 hippie 207 201 33 33 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 1 hippie 363 686 87 87 3
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NSMAF_ENST00000038176 NSMAF Q92636 Protein FAN chr8 Not Cancer Driver No 1 intact, hippie 118 80 13 13 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NXF5_ENST00000537026 NXF5 Q9H1B4 Nuclear RNA export factor 5 chrX Not Cancer Driver No 1 hippie, biogrid 92 4 3 3 0
OASL OASL Q15646 2'-5'-oligoadenylate synthase-like protein chr12 Not Cancer Driver No 1 intact, hippie 76 8 4 4 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
ODAPH_ENST00000311623 ODAPH Q17RF5 Odontogenesis associated phosphoprotein chr4 Not Cancer Driver No 1 intact, hippie 28 48 14 14 0
ODF1 ODF1 Q14990 Outer dense fiber protein 1 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 52 0 0 0 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
OLR1 OLR1 P78380 Oxidized low-density lipoprotein receptor 1 chr12 Not Cancer Driver No 1 intact, hippie 38 75 8 8 0
P4HA2_ENST00000379104 P4HA2 O15460 Prolyl 4-hydroxylase subunit alpha-2 chr5 Not Cancer Driver No 1 hippie, biogrid 66 82 12 12 2
PACRG PACRG Q96M98 Parkin coregulated gene protein chr6 Not Cancer Driver No 1 hippie 66 45 6 6 0
PAFAH1B2 PAFAH1B2 P68402 Platelet-activating factor acetylhydrolase IB subunit alpha2 chr11 Census Yes 1 hippie, biogrid 25 43 1 1 0
PAGE4_ENST00000376141 PAGE4 O60829 P antigen family member 4 chrX Not Cancer Driver No 1 hippie 20 102 20 20 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PC PC P11498 Pyruvate carboxylase, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 185 172 27 27 9
PCBP1 PCBP1 Q15365 Poly(rC)-binding protein 1 chr2 Census, Compendium Yes 1 hippie 65 166 24 24 0
PCGF6 PCGF6 Q9BYE7 Polycomb group RING finger protein 6 chr10 Not Cancer Driver No 1 hippie 29 142 11 11 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PDCL PDCL Q13371 Phosducin-like protein chr9 Not Cancer Driver No 3 intact, hippie, biogrid 33 146 13 13 0
PDCL3 PDCL3 Q9H2J4 Phosducin-like protein 3 chr2 Not Cancer Driver No 3 hippie, biogrid 48 73 13 13 0
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie, biogrid 52 50 10 10 0
PDK3_ENST00000379162 PDK3 Q15120 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial chrX Not Cancer Driver No 2 hippie, biogrid 61 28 6 6 1
PDK4 PDK4 Q16654 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 70 14 2 2 0
PEX14 PEX14 O75381 Peroxisomal membrane protein PEX14 chr1 Not Cancer Driver No 1 hippie 38 266 28 28 0
PEX7 PEX7 O00628 Peroxisomal targeting signal 2 receptor chr6 Not Cancer Driver No 4 intact, hippie, biogrid 32 0 0 0 2
PFDN2 PFDN2 Q9UHV9 Prefoldin subunit 2 chr1 Not Cancer Driver No 1 hippie, biogrid 18 111 11 11 0
PFDN4 PFDN4 Q9NQP4 Prefoldin subunit 4 chr20 Not Cancer Driver No 1 hippie, biogrid 22 40 6 6 0
PFDN5 PFDN5 Q99471 Prefoldin subunit 5 chr12 Not Cancer Driver No 1 hippie, biogrid 18 3 0 0 0
PGAM4 PGAM4 Q8N0Y7 Probable phosphoglycerate mutase 4 chrX Not Cancer Driver No 1 hippie, biogrid 42 62 9 9 0
PGK1 PGK1 P00558 Phosphoglycerate kinase 1 chrX Not Cancer Driver No 1 intact 61 40 5 5 9
PHKG2 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 Not Cancer Driver No 1 hippie 48 50 6 6 4
PHOSPHO1_ENST00000310544 PHOSPHO1 Q8TCT1 Phosphoethanolamine/phosphocholine phosphatase chr17 Not Cancer Driver No 1 intact, hippie 14 18 0 0 0
PI4K2B PI4K2B Q8TCG2 Phosphatidylinositol 4-kinase type 2-beta chr4 Not Cancer Driver No 1 intact, hippie 51 99 4 4 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PIK3R4 PIK3R4 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 chr3 Not Cancer Driver No 1 hippie, biogrid 193 315 45 45 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PKDCC PKDCC Q504Y2 Extracellular tyrosine-protein kinase PKDCC chr2 Not Cancer Driver No 1 intact, hippie, biogrid 36 124 0 0 0
PLAC8L1 PLAC8L1 A1L4L8 PLAC8-like protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 24 0 0 0 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 hippie 152 919 121 121 0
PNPLA1 PNPLA1 Q8N8W4 Omega-hydroxyceramide transacylase chr6 Not Cancer Driver No 2 hippie, biogrid 89 253 48 48 2
PNPLA5 PNPLA5 Q7Z6Z6 Patatin-like phospholipase domain-containing protein 5 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 78 33 8 8 0
POC1A POC1A Q8NBT0 POC1 centriolar protein homolog A chr3 Not Cancer Driver No 3 hippie, biogrid 51 88 8 8 1
POC1B POC1B Q8TC44 POC1 centriolar protein homolog B chr12 Not Cancer Driver No 2 intact, hippie, biogrid 52 86 8 8 1
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 Census, Compendium Yes 1 hippie 179 214 31 31 2
POLR1C POLR1C O15160 DNA-directed RNA polymerases I and III subunit RPAC1 chr6 Not Cancer Driver No 1 hippie 34 28 3 3 13
POLR2C POLR2C P19387 DNA-directed RNA polymerase II subunit RPB3 chr16 Not Cancer Driver No 1 hippie, biogrid 34 108 11 11 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 72 44 4 4 3
PPM1J PPM1J Q5JR12 Protein phosphatase 1J chr1 Not Cancer Driver No 1 intact, hippie 51 206 16 16 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 3 intact, hippie 41 12 1 1 8
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 Not Cancer Driver No 3 intact, hippie 37 12 0 0 0
PPP2R2A_ENST00000380737 PPP2R2A P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform chr8 Not Cancer Driver No 1 hippie 60 68 10 10 0
PPP2R2B_ENST00000394409 PPP2R2B Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform chr5 Not Cancer Driver No 2 intact, hippie 101 76 22 22 0
PPP2R2C_ENST00000382599 PPP2R2C Q9Y2T4 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform chr4 Not Cancer Driver No 6 intact, hippie, biogrid 78 78 13 13 0
PPP2R2D PPP2R2D Q66LE6 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform chr10 Not Cancer Driver No 1 hippie 50 65 9 9 0
PPP4C_ENST00000561610 PPP4C P60510 Serine/threonine-protein phosphatase 4 catalytic subunit chr16 Not Cancer Driver No 2 hippie, biogrid 41 0 0 0 0
PPP4R2 PPP4R2 Q9NY27 Serine/threonine-protein phosphatase 4 regulatory subunit 2 chr3 Not Cancer Driver No 1 hippie 32 314 26 26 0
PPP6C_ENST00000373547 PPP6C O00743 Serine/threonine-protein phosphatase 6 catalytic subunit chr9 Census, Compendium Yes 1 intact, hippie 63 0 0 0 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 Not Cancer Driver No 1 hippie 37 0 0 0 23
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 Not Cancer Driver No 1 hippie, biogrid 24 30 4 4 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 72 124 17 17 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
PRKACB_ENST00000370689 PRKACB P22694 cAMP-dependent protein kinase catalytic subunit beta chr1 Not Cancer Driver No 1 hippie 50 26 6 6 4
PRKACG PRKACG P22612 cAMP-dependent protein kinase catalytic subunit gamma chr9 Not Cancer Driver No 1 intact, hippie, biogrid 74 23 7 7 1
PRKAG3_ENST00000529249 PRKAG3 Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 74 144 25 25 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 2 intact, hippie 110 78 15 15 31
PRPF4 PRPF4 O43172 U4/U6 small nuclear ribonucleoprotein Prp4 chr9 Not Cancer Driver No 1 hippie 61 152 15 15 2
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PSMA2 PSMA2 P25787 Proteasome subunit alpha type-2 chr7 Not Cancer Driver No 1 hippie 20 0 0 0 0
PSMA3 PSMA3 P25788 Proteasome subunit alpha type-3 chr14 Not Cancer Driver No 1 hippie 27 30 5 5 0
PSMA5 PSMA5 P28066 Proteasome subunit alpha type-5 chr1 Not Cancer Driver No 1 hippie, biogrid 24 23 1 1 0
PSMA6 PSMA6 P60900 Proteasome subunit alpha type-6 chr14 Not Cancer Driver No 1 hippie, biogrid 37 2 1 1 0
PSMB8 PSMB8 P28062 Proteasome subunit beta type-8 chr6 Not Cancer Driver No 1 hippie, biogrid 43 62 7 7 3
PSMC2_ENST00000292644 PSMC2 P35998 26S proteasome regulatory subunit 7 chr7 Not Cancer Driver No 1 hippie, biogrid 63 120 13 13 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie 23 67 6 6 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 505 76 4 4 41
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 Census Yes 1 hippie 42 12 0 0 0
PTPA_ENST00000337738 PTPA Q15257 Serine/threonine-protein phosphatase 2A activator chr9 Not Cancer Driver No 1 intact, hippie 40 63 2 2 0
PTPRR PTPRR Q15256 Receptor-type tyrosine-protein phosphatase R chr12 Not Cancer Driver No 1 intact, hippie 172 73 28 28 0
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 1 hippie 115 421 74 74 3
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 2 intact, hippie 89 169 38 38 22
RAP2C_ENST00000370874 RAP2C Q9Y3L5 Ras-related protein Rap-2c chrX Not Cancer Driver No 2 intact, hippie, biogrid 32 8 2 2 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RBM3_ENST00000376755 RBM3 P98179 RNA-binding protein 3 chrX Not Cancer Driver No 1 hippie 22 134 18 18 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 Not Cancer Driver No 1 hippie 128 703 81 81 0
RDH8 RDH8 K7ELF7 Retinol dehydrogenase chr19 Not Cancer Driver No 1 hippie, biogrid 81 30 8 8 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RFWD3 RFWD3 Q6PCD5 E3 ubiquitin-protein ligase RFWD3 chr16 Census Yes 1 intact, hippie 68 318 30 30 1
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 hippie 137 417 61 61 0
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 Not Cancer Driver No 1 hippie 69 301 37 37 0
RIOK2 RIOK2 Q9BVS4 Serine/threonine-protein kinase RIO2 chr5 Not Cancer Driver No 1 hippie 68 253 33 33 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie 119 232 34 34 3
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 167 220 28 28 0
RNF181 RNF181 Q9P0P0 E3 ubiquitin-protein ligase RNF181 chr2 Not Cancer Driver No 1 hippie 15 63 8 8 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 Not Cancer Driver No 1 hippie 142 319 45 45 0
RPE65 RPE65 Q16518 Retinoid isomerohydrolase chr1 Not Cancer Driver No 1 hippie, biogrid 109 10 1 1 44
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 2 intact, hippie, biogrid 50 69 3 3 0
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 intact 53 26 4 4 0
RPS4Y1 RPS4Y1 P22090 40S ribosomal protein S4, Y isoform 1 chrY Not Cancer Driver No 1 hippie, biogrid 10 34 0 0 0
RPS6KB2 RPS6KB2 Q9UBS0 Ribosomal protein S6 kinase beta-2 chr11 Not Cancer Driver No 1 hippie 54 194 16 16 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 Not Cancer Driver No 1 hippie 176 241 21 21 0
RTF1 RTF1 Q92541 RNA polymerase-associated protein RTF1 homolog chr15 Not Cancer Driver No 1 intact 83 568 67 67 0
RTN2 RTN2 O75298 Reticulon-2 chr19 Not Cancer Driver No 1 intact 85 270 55 55 1
SAMM50 SAMM50 Q9Y512 Sorting and assembly machinery component 50 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 51 34 1 1 0
SEC31B SEC31B Q9NQW1 Protein transport protein Sec31B chr10 Not Cancer Driver No 3 intact, hippie, biogrid 167 421 64 64 0
SEH1L_ENST00000262124 SEH1L Q96EE3 Nucleoporin SEH1 chr18 Not Cancer Driver No 1 hippie 40 71 11 11 0
SFI1 SFI1 A8K8P3 Protein SFI1 homolog chr22 Not Cancer Driver No 1 intact 128 265 28 28 0
SGK2_ENST00000373100 SGK2 Q9HBY8 Serine/threonine-protein kinase Sgk2 chr20 Not Cancer Driver No 1 intact, hippie 84 52 10 10 0
SH3BP4_ENST00000392011 SH3BP4 Q9P0V3 SH3 domain-binding protein 4 chr2 Not Cancer Driver No 1 hippie 143 241 43 43 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 57 58 5 5 1
SIK3 SIK3 Q9Y2K2 Serine/threonine-protein kinase SIK3 chr11 Not Cancer Driver No 1 hippie, biogrid 143 964 107 107 1
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SKI SKI P12755 Ski oncogene chr1 Census Yes 1 hippie 44 432 26 26 14
SLC25A1 SLC25A1 P53007 Tricarboxylate transport protein, mitochondrial chr22 Not Cancer Driver No 1 hippie 22 34 2 2 17
SLC25A3 SLC25A3 Q00325 Phosphate carrier protein, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 49 32 4 4 1
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 Not Cancer Driver No 1 hippie 177 34 8 8 0
SMAP2 SMAP2 Q8WU79 Stromal membrane-associated protein 2 chr1 Not Cancer Driver No 1 hippie 50 214 30 30 0
SMOX_ENST00000305958 SMOX Q9NWM0 Spermine oxidase chr20 Not Cancer Driver No 2 intact, hippie, biogrid 79 164 23 23 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 52 97 11 11 0
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 Census Yes 1 intact 127 258 48 48 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 62 488 56 56 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 Census, Compendium Yes 1 intact, hippie 22 66 3 3 2
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SPDL1 SPDL1 Q96EA4 Protein Spindly chr5 Not Cancer Driver No 1 hippie 75 342 43 43 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 73 252 38 38 1
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
SSSCA1 ZNRD2 O60232 Protein ZNRD2 chr11 Not Cancer Driver No 2 intact 19 103 12 12 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STK24 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 Not Cancer Driver No 1 intact, hippie 67 118 16 16 0
STK25 STK25 O00506 Serine/threonine-protein kinase 25 chr2 Not Cancer Driver No 1 hippie 42 170 15 15 0
STK32A_ENST00000397936 STK32A Q8WU08 Serine/threonine-protein kinase 32A chr5 Not Cancer Driver No 1 intact, hippie, biogrid 48 74 10 10 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 2 intact, hippie 70 231 30 30 0
STOM STOM P27105 Stomatin chr9 Not Cancer Driver No 1 hippie, biogrid 23 44 3 3 0
STRADA STRADA Q7RTN6 STE20-related kinase adapter protein alpha chr17 Not Cancer Driver No 1 intact, hippie, biogrid 49 118 14 14 0
STRADB STRADB Q9C0K7 STE20-related kinase adapter protein beta chr2 Not Cancer Driver No 2 intact, hippie, biogrid 53 84 7 7 0
STRN STRN O43815 Striatin chr2 Census, Compendium Yes 3 intact, hippie 97 348 43 43 0
STRN3 STRN3 Q13033 Striatin-3 chr14 Not Cancer Driver No 1 hippie 93 366 42 42 0
STRN4_ENST00000263280 STRN4 Q9NRL3 Striatin-4 chr19 Not Cancer Driver No 1 hippie 84 407 40 40 0
SUCLG2_ENST00000307227 SUCLG2 Q96I99 Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 48 12 2 2 0
SUMF2_ENST00000275607 SUMF2 Q8NBJ7-2 Isoform 2 of Inactive C-alpha-formylglycine-generating enzyme 2 chr7 Not Cancer Driver No 1 hippie, biogrid 27 75 12 12 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 7 87 5 5 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX Not Cancer Driver No 1 intact, hippie 59 15 1 1 0
SUV39H2 SUV39H2 Q9H5I1 Histone-lysine N-methyltransferase SUV39H2 chr10 Not Cancer Driver No 1 hippie 39 23 1 1 0
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 1 hippie 83 483 46 46 3
TAF11 TAF11 Q15544 Transcription initiation factor TFIID subunit 11 chr6 Not Cancer Driver No 1 intact 22 137 16 16 0
TAF1C TAF1C Q15572 TATA box-binding protein-associated factor RNA polymerase I subunit C chr16 Not Cancer Driver No 1 hippie, biogrid 114 312 35 35 0
TAF5 TAF5 Q15542 Transcription initiation factor TFIID subunit 5 chr10 Not Cancer Driver No 2 intact 61 294 12 12 0
TATDN1 TATDN1 Q6P1N9 Deoxyribonuclease TATDN1 chr8 Not Cancer Driver No 1 hippie, biogrid 25 0 0 0 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 1 intact, hippie 101 42 5 5 12
TBL1Y TBL1Y Q9BQ87 F-box-like/WD repeat-containing protein TBL1Y chrY Not Cancer Driver No 2 intact, hippie, biogrid 31 138 8 8 0
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 Not Cancer Driver No 7 intact, hippie, biogrid 54 55 10 10 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 68 169 23 23 0
THOC3 THOC3 Q96J01 THO complex subunit 3 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 26 23 2 2 0
TLE2_ENST00000262953 TLE2 Q04725 Transducin-like enhancer protein 2 chr19 Not Cancer Driver No 2 hippie, biogrid 78 283 29 29 0
TMEM41B_ENST00000611268 TMEM41B Q5BJD5 Transmembrane protein 41B chr11 Not Cancer Driver No 1 hippie 19 47 3 3 0
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie 78 412 52 52 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TNK2_ENST00000333602 TNK2 Q07912 Activated CDC42 kinase 1 chr3 Not Cancer Driver No 1 hippie 137 593 81 81 0
TP53RK TP53RK Q96S44 EKC/KEOPS complex subunit TP53RK chr20 Not Cancer Driver No 1 hippie 20 51 2 2 3
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 2 intact, hippie 2891 282 1466 1466 83
TPI1_ENST00000396705 TPI1 P60174 Triosephosphate isomerase chr12 Not Cancer Driver No 1 intact 40 15 2 2 7
TRAF3IP3 TRAF3IP3 Q9Y228 TRAF3-interacting JNK-activating modulator chr1 Not Cancer Driver No 1 hippie 90 347 63 63 0
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 Not Cancer Driver No 1 hippie, biogrid 65 114 24 24 0
TRIM14 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 Not Cancer Driver No 1 hippie 36 93 7 7 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRIM68 TRIM68 Q6AZZ1 E3 ubiquitin-protein ligase TRIM68 chr11 Not Cancer Driver No 1 hippie, biogrid 74 37 7 7 0
TSSK3 TSSK3 Q96PN8 Testis-specific serine/threonine-protein kinase 3 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 30 0 0 0 0
TSSK6 TSSK6 Q9BXA6 Testis-specific serine/threonine-protein kinase 6 chr19 Not Cancer Driver No 2 hippie, biogrid 47 0 0 0 0
TTC27 TTC27 Q6P3X3 Tetratricopeptide repeat protein 27 chr2 Not Cancer Driver No 1 hippie 109 40 5 5 0
TTLL3_ENST00000430793 TTLL3 Q9Y4R7-5 Isoform 3 of Tubulin monoglycylase TTLL3 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 47 57 2 2 0
TTLL9_ENST00000375938 TTLL9 Q3SXZ7 Probable tubulin polyglutamylase TTLL9 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 88 73 11 11 0
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 3 intact, hippie, biogrid 59 52 11 11 8
TUBA1B TUBA1B P68363 Tubulin alpha-1B chain chr12 Not Cancer Driver No 2 intact, hippie, biogrid 41 52 9 9 0
TUBA1C_ENST00000301072 TUBA1C Q9BQE3 Tubulin alpha-1C chain chr12 Not Cancer Driver No 1 intact, hippie 39 50 5 5 0
TUBA3C TUBA3C P0DPH7 Tubulin alpha-3C chain chr13 Not Cancer Driver No 3 biogrid 185 36 14 14 0
TUBA3D TUBA3D P0DPH8 Tubulin alpha-3D chain chr2 Not Cancer Driver No 1 hippie 74 36 4 4 0
TUBA3E TUBA3E Q6PEY2 Tubulin alpha-3E chain chr2 Not Cancer Driver No 1 hippie, biogrid 92 35 9 9 0
TUBA4A TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 2 hippie, biogrid 73 39 4 4 5
TUBAL3 TUBAL3 A6NHL2 Tubulin alpha chain-like 3 chr10 Not Cancer Driver No 3 intact, hippie, biogrid 85 25 3 3 0
TUBB1 TUBB1 Q9H4B7 Tubulin beta-1 chain chr20 Not Cancer Driver No 1 hippie, biogrid 71 38 4 4 1
TUBB2B TUBB2B Q9BVA1 Tubulin beta-2B chain chr6 Not Cancer Driver No 3 intact, hippie, biogrid 43 68 10 10 10
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 intact, hippie 67 53 10 10 12
TUBB4A TUBB4A P04350 Tubulin beta-4A chain chr19 Not Cancer Driver No 1 hippie, biogrid 91 61 16 16 2
TUBB6 TUBB6 Q9BUF5 Tubulin beta-6 chain chr18 Not Cancer Driver No 1 hippie, biogrid 69 51 5 5 1
TUBB8 TUBB8 Q3ZCM7 Tubulin beta-8 chain chr10 Not Cancer Driver No 1 hippie, biogrid 103 53 18 18 13
TUBD1_ENST00000592426 TUBD1 Q9UJT1 Tubulin delta chain chr17 Not Cancer Driver No 2 intact, hippie, biogrid 54 3 0 0 0
TUBG1 TUBG1 P23258 Tubulin gamma-1 chain chr17 Not Cancer Driver No 3 intact, hippie 51 44 10 10 3
TUBG2 TUBG2 Q9NRH3 Tubulin gamma-2 chain chr17 Not Cancer Driver No 2 hippie, biogrid 51 48 4 4 0
TXNDC9 TXNDC9 O14530 Thioredoxin domain-containing protein 9 chr2 Not Cancer Driver No 3 hippie, biogrid 20 40 5 5 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 Not Cancer Driver No 1 intact, hippie 148 213 29 29 0
UBASH3B UBASH3B Q8TF42 Ubiquitin-associated and SH3 domain-containing protein B chr11 Not Cancer Driver No 1 hippie 86 73 6 6 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UBE2Z UBE2Z Q9H832 Ubiquitin-conjugating enzyme E2 Z chr17 Not Cancer Driver No 1 hippie 27 140 10 10 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
UCHL3 UCHL3 P15374 Ubiquitin carboxyl-terminal hydrolase isozyme L3 chr13 Not Cancer Driver No 1 hippie 26 61 3 3 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
ULK3 ULK3 Q6PHR2 Serine/threonine-protein kinase ULK3 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 37 55 2 2 0
UQCRC2 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 53 48 13 13 1
USP10_ENST00000219473 USP10 Q14694 Ubiquitin carboxyl-terminal hydrolase 10 chr16 Not Cancer Driver No 1 hippie 92 425 49 49 0
USP11 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 1 hippie 140 210 28 28 0
UTP18 UTP18 Q9Y5J1 U3 small nucleolar RNA-associated protein 18 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 49 250 21 21 0
VAV2 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 Not Cancer Driver No 1 intact, hippie 127 135 17 17 0
VBP1 VBP1 P61758 Prefoldin subunit 3 chrX Not Cancer Driver No 1 hippie, biogrid 27 47 7 7 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 188 110 28 28 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 142 117 36 36 133
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WDR34 DYNC2I2 Q96EX3 Cytoplasmic dynein 2 intermediate chain 2 chr9 Not Cancer Driver No 1 intact 50 123 10 10 10
WDR37_ENST00000263150 WDR37 Q9Y2I8 WD repeat-containing protein 37 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 63 154 16 16 4
WDR46 WDR46 O15213 WD repeat-containing protein 46 chr6 Not Cancer Driver No 1 hippie, biogrid 61 297 23 23 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 2 hippie, biogrid 30 35 3 3 0
WDR5B WDR5B Q86VZ2 WD repeat-containing protein 5B chr3 Not Cancer Driver No 2 intact, hippie, biogrid 35 29 5 5 0
WDR61 WDR61 Q9GZS3 WD repeat-containing protein 61 chr15 Not Cancer Driver No 1 hippie, biogrid 25 7 1 1 0
WDR70 WDR70 Q9NW82 WD repeat-containing protein 70 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 97 363 57 57 0
WDR74_ENST00000278856 WDR74 Q6RFH5 WD repeat-containing protein 74 chr11 Not Cancer Driver No 1 hippie, biogrid 44 177 21 21 0
WDR76 WDR76 Q9H967 WD repeat-containing protein 76 chr15 Not Cancer Driver No 1 hippie 60 288 33 33 0
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 30 41 2 2 0
WDR82 WDR82 Q6UXN9 WD repeat-containing protein 82 chr3 Not Cancer Driver No 1 hippie 35 0 0 0 0
WDR83 WDR83 Q9BRX9 WD repeat domain-containing protein 83 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 28 35 3 3 0
WDR86_ENST00000334493 WDR86 Q86TI4 WD repeat-containing protein 86 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 51 20 4 4 0
WDR89 WDR89 Q96FK6 WD repeat-containing protein 89 chr14 Not Cancer Driver No 1 hippie, biogrid 33 56 4 4 0
WDR92 DNAAF10 Q96MX6 Dynein axonemal assembly factor 10 chr2 Not Cancer Driver No 1 intact 36 42 6 6 0
WDTC1 WDTC1 Q8N5D0 WD and tetratricopeptide repeats protein 1 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 81 154 21 21 0
WIPI2 WIPI2 Q9Y4P8 WD repeat domain phosphoinositide-interacting protein 2 chr7 Not Cancer Driver No 1 hippie 64 68 5 5 1
WRAP53 WRAP53 Q9BUR4 Telomerase Cajal body protein 1 chr17 Not Cancer Driver No 2 hippie, biogrid 66 232 29 29 4
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 Not Cancer Driver No 1 intact, hippie 24 35 2 2 1
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 intact, hippie 66 140 12 12 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie 65 62 10 10 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 intact, hippie 30 81 10 10 0
ZBTB18_ENST00000622512 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 78 236 25 25 0
ZBTB38_ENST00000441582 ZBTB38 Q8NAP3 Zinc finger and BTB domain-containing protein 38 chr3 Not Cancer Driver No 1 hippie 137 648 73 73 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0
ZC3H7A_ENST00000355758 ZC3H7A Q8IWR0 Zinc finger CCCH domain-containing protein 7A chr16 Not Cancer Driver No 1 hippie 91 224 23 23 0
ZFYVE27_ENST00000393677 ZFYVE27 Q5T4F4 Protrudin chr10 Not Cancer Driver No 1 hippie 45 140 22 22 1
ZNF746_ENST00000340622 ZNF746 Q6NUN9 Zinc finger protein 746 chr7 Not Cancer Driver No 1 hippie 93 436 56 56 0