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CBS_ENST00000359624 ,CBS ,P35520
  • Uniprot Accession= P35520
  • Ensembl Transcript= ENST00000359624.7
  • Uniprot Name= CBS
  • Name= Cystathionine beta-synthase
  • Chromosome= chr21
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 30
  • Number of Interaction partner in biogrid: 23
  • Number of Interaction partner in hippie: 112
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 84 28 5 5 1
AP1B1 AP1B1 Q10567 AP-1 complex subunit beta-1 chr22 Not Cancer Driver No 1 hippie, biogrid 114 119 10 10 1
ARHGAP11B ARHGAP11B Q3KRB8 Inactive Rho GTPase-activating protein 11B chr15 Not Cancer Driver No 1 intact, hippie, biogrid 20 17 1 1 0
ARHGAP26 ARHGAP26 Q9UNA1 Rho GTPase-activating protein 26 chr5 Census Yes 1 hippie, biogrid 99 259 26 26 1
ARHGAP29 ARHGAP29 Q52LW3 Rho GTPase-activating protein 29 chr1 Not Cancer Driver No 1 hippie, biogrid 182 579 94 94 0
ARHGAP32 ARHGAP32 A7KAX9 Rho GTPase-activating protein 32 chr11 Not Cancer Driver No 1 hippie, biogrid 268 1476 193 193 0
ARHGAP35_ENST00000614079 ARHGAP35 Q9NRY4 Rho GTPase-activating protein 35 chr19 Census, Compendium Yes 1 hippie, biogrid 255 409 58 58 0
ASNS_ENST00000394308 ASNS P08243 Asparagine synthetase [glutamine-hydrolyzing] chr7 Not Cancer Driver No 1 hippie, biogrid 81 11 0 0 3
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 biogrid 29 195 9 9 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
CAMK2A_ENST00000348628 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 Not Cancer Driver No 1 intact, hippie 83 62 10 10 7
CBS_ENST00000359624 CBS P35520 Cystathionine beta-synthase chr21 Not Cancer Driver No 7 intact, hippie 61 160 19 19 103
CBX4 CBX4 O00257 E3 SUMO-protein ligase CBX4 chr17 Not Cancer Driver No 1 hippie 72 477 63 63 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
COL4A3BP_ENST00000261415 CERT1 Q9Y5P4 Ceramide transfer protein chr5 Not Cancer Driver No 1 intact 73 215 23 23 2
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
CTBP2_ENST00000494626 CTBP2 P56545 C-terminal-binding protein 2 chr10 Not Cancer Driver No 1 hippie 48 94 4 4 0
CTH CTH P32929 Cystathionine gamma-lyase chr1 Not Cancer Driver No 1 hippie, biogrid 45 49 6 6 2
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CYTH1_ENST00000446868 CYTH1 Q15438 Cytohesin-1 chr17 Not Cancer Driver No 1 hippie 59 93 15 15 0
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 Census, Compendium Yes 1 intact, hippie 106 549 81 81 0
DBNL_ENST00000448521 DBNL Q9UJU6 Drebrin-like protein chr7 Not Cancer Driver No 1 hippie 46 304 31 31 0
DERA DERA Q9Y315 Deoxyribose-phosphate aldolase chr12 Not Cancer Driver No 1 hippie 33 2 0 0 0
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 hippie, biogrid 109 100 14 14 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EHHADH EHHADH Q08426 Peroxisomal bifunctional enzyme chr3 Not Cancer Driver No 2 intact, hippie 116 74 14 14 1
EIF3B_ENST00000397011 EIF3B P55884 Eukaryotic translation initiation factor 3 subunit B chr7 Not Cancer Driver No 1 hippie 89 226 4 4 0
ENOPH1 ENOPH1 Q9UHY7 Enolase-phosphatase E1 chr4 Not Cancer Driver No 1 hippie, biogrid 35 14 2 2 0
ERO1A ERO1A Q96HE7 ERO1-like protein alpha chr14 Not Cancer Driver No 1 hippie 48 32 5 5 0
FKBP6 FKBP6 O75344 Inactive peptidyl-prolyl cis-trans isomerase FKBP6 chr7 Not Cancer Driver No 1 hippie 75 17 1 1 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 intact, hippie 88 312 53 53 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 Not Cancer Driver No 3 intact, hippie 68 388 42 42 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 Not Cancer Driver No 1 hippie 9 11 0 0 0
GAL GAL P22466 Galanin peptides chr11 Not Cancer Driver No 1 intact, hippie 17 36 2 2 1
GON7 GON7 Q9BXV9 EKC/KEOPS complex subunit GON7 chr14 Not Cancer Driver No 1 hippie 9 100 9 9 0
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 Census Yes 1 hippie 56 263 34 34 0
GPN1_ENST00000610189 GPN1 Q9HCN4 GPN-loop GTPase 1 chr2 Not Cancer Driver No 1 hippie 39 117 14 14 0
GPSM1 GPSM1 Q86YR5 G-protein-signaling modulator 1 chr9 Not Cancer Driver No 1 hippie 68 344 35 35 0
HGS HGS O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 Not Cancer Driver No 1 hippie 109 528 74 74 0
HID1 HID1 Q8IV36 Protein HID1 chr17 Not Cancer Driver No 2 intact, hippie 102 153 14 14 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 Not Cancer Driver No 1 hippie 59 335 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 intact, hippie 100 254 43 43 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie 149 251 52 52 0
HSPE1 HSPE1 P61604 10 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 8 3 0 0 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 2 intact, hippie 336 666 69 69 2
IPO4 IPO4 Q8TEX9 Importin-4 chr14 Not Cancer Driver No 1 hippie 106 87 5 5 0
IREB2 IREB2 P48200 Iron-responsive element-binding protein 2 chr15 Not Cancer Driver No 1 hippie 126 107 13 13 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 Not Cancer Driver No 1 intact, hippie 65 173 21 21 3
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 Not Cancer Driver No 1 hippie 61 277 50 50 0
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LRSAM1_ENST00000373322 LRSAM1 Q6UWE0 E3 ubiquitin-protein ligase LRSAM1 chr9 Not Cancer Driver No 1 hippie 86 240 30 30 1
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NEDD8 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 10 36 5 5 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 Not Cancer Driver No 2 intact, hippie 35 23 0 0 0
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 69 252 26 26 16
NMD3_ENST00000351193 NMD3 Q96D46 60S ribosomal export protein NMD3 chr3 Not Cancer Driver No 1 hippie, biogrid 67 104 20 20 0
NPLOC4 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 Not Cancer Driver No 1 hippie 78 47 8 8 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUCB1 NUCB1 Q02818 Nucleobindin-1 chr19 Not Cancer Driver No 1 hippie 56 352 43 43 0
OAT OAT P04181 Ornithine aminotransferase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 52 17 0 0 27
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 58 470 51 51 6
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 31 33 2 2 0
PA2G4 PA2G4 Q9UQ80 Proliferation-associated protein 2G4 chr12 Not Cancer Driver No 2 intact, hippie 45 128 18 18 0
PAGE4_ENST00000376141 PAGE4 O60829 P antigen family member 4 chrX Not Cancer Driver No 1 hippie 20 102 20 20 0
PARP6 PARP6 Q2NL67 Protein mono-ADP-ribosyltransferase PARP6 chr15 Not Cancer Driver No 1 hippie 87 67 13 13 0
PDLIM5_ENST00000317968 PDLIM5 Q96HC4 PDZ and LIM domain protein 5 chr4 Not Cancer Driver No 1 hippie 89 372 57 57 0
PIAS1_ENST00000249636 PIAS1 O75925 E3 SUMO-protein ligase PIAS1 chr15 Not Cancer Driver No 1 hippie 80 241 43 43 0
PIAS2 PIAS2 O75928 E3 SUMO-protein ligase PIAS2 chr18 Not Cancer Driver No 1 hippie 78 209 28 28 0
PIAS3 PIAS3 Q9Y6X2 E3 SUMO-protein ligase PIAS3 chr1 Not Cancer Driver No 1 hippie 70 266 31 31 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 Not Cancer Driver No 1 hippie 17 115 12 12 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLIN3 PLIN3 O60664 Perilipin-3 chr19 Not Cancer Driver No 1 hippie 44 256 34 34 0
PREX1 PREX1 Q8TCU6 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein chr20 Not Cancer Driver No 1 intact, hippie, biogrid 297 307 55 55 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 intact, hippie 53 24 0 0 2
PRKAG1_ENST00000548065 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 Not Cancer Driver No 1 intact, hippie 35 25 2 2 0
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 Census, Compendium Yes 1 hippie 39 66 11 11 17
PSMA1_ENST00000396394 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 Not Cancer Driver No 2 intact, hippie 48 51 9 9 0
PTPRR PTPRR Q15256 Receptor-type tyrosine-protein phosphatase R chr12 Not Cancer Driver No 1 hippie 172 73 28 28 0
RAD23B RAD23B P54727 UV excision repair protein RAD23 homolog B chr9 Not Cancer Driver No 1 hippie 54 324 41 41 0
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 Not Cancer Driver No 1 hippie 73 413 30 30 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RSU1_ENST00000345264 RSU1 Q15404 Ras suppressor protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 25 61 4 4 0
RTF2_ENST00000357348 RTF2 Q9BY42 Replication termination factor 2 chr20 Not Cancer Driver No 1 hippie 44 170 22 22 0
SEC24B_ENST00000265175 SEC24B O95487 Protein transport protein Sec24B chr4 Not Cancer Driver No 1 hippie, biogrid 135 526 55 55 0
SEC31A_ENST00000355196 SEC31A O94979 Protein transport protein Sec31A chr4 Not Cancer Driver No 1 hippie, biogrid 139 519 58 58 0
SKIV2L SKIV2L Q15477 Helicase SKI2W chr6 Not Cancer Driver No 1 hippie, biogrid 140 390 54 54 1
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 52 97 11 11 0
SRP14 SRP14 P37108 Signal recognition particle 14 kDa protein chr15 Not Cancer Driver No 1 hippie 10 74 8 8 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 Not Cancer Driver No 1 intact, hippie 33 234 29 29 8
TPT1_ENST00000530705 TPT1 P13693 Translationally-controlled tumor protein chr13 Not Cancer Driver No 1 intact, hippie 17 43 6 6 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 Not Cancer Driver No 2 intact, hippie 74 110 11 11 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 hippie 84 219 33 33 0
UBA5 UBA5 Q9GZZ9 Ubiquitin-like modifier-activating enzyme 5 chr3 Not Cancer Driver No 1 hippie 41 126 8 8 7
UBASH3A UBASH3A P57075 Ubiquitin-associated and SH3 domain-containing protein A chr21 Not Cancer Driver No 2 intact, hippie 101 27 8 8 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 3 intact, hippie 16 16 3 3 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 Not Cancer Driver No 1 hippie 25 24 3 3 0
UBE3B_ENST00000434735 UBE3B Q7Z3V4 Ubiquitin-protein ligase E3B chr12 Not Cancer Driver No 1 hippie, biogrid 151 13 0 0 1
UGP2 UGP2 Q16851 UTP--glucose-1-phosphate uridylyltransferase chr2 Not Cancer Driver No 1 hippie 65 55 7 7 1
VBP1 VBP1 P61758 Prefoldin subunit 3 chrX Not Cancer Driver No 1 hippie, biogrid 27 47 7 7 0
VTA1 VTA1 Q9NP79 Vacuolar protein sorting-associated protein VTA1 homolog chr6 Not Cancer Driver No 2 intact, hippie 49 152 25 25 0
WDYHV1 NTAQ1 Q96HA8 Protein N-terminal glutamine amidohydrolase chr8 Not Cancer Driver No 1 intact 38 26 3 3 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
ZDHHC17 ZDHHC17 Q8IUH5 Palmitoyltransferase ZDHHC17 chr12 Not Cancer Driver No 1 hippie 84 49 9 9 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0
ZMYM5_ENST00000337963 ZMYM5 Q9UJ78 Zinc finger MYM-type protein 5 chr13 Not Cancer Driver No 1 intact, hippie 67 374 40 40 0