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CASP9 ,CASP9 ,P55211
  • Uniprot Accession= P55211
  • Ensembl Transcript= ENST00000333868.9
  • Uniprot Name= CASP9
  • Name= Caspase-9
  • Chromosome= chr1
  • Driver status= Census
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 1
  • Number of Interaction partner in hippie: 70
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 139 604 73 73 2
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 Not Cancer Driver No 1 hippie 32 16 2 2 0
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 Not Cancer Driver No 1 hippie 215 1770 214 214 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 Not Cancer Driver No 1 hippie 127 17 1 1 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 Census Yes 1 hippie 77 511 56 56 0
ATG7 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 Compendium Yes 1 hippie 77 53 8 8 6
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 Census Yes 1 hippie 30 39 2 2 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 Census, Compendium Yes 1 hippie 36 151 25 25 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 Not Cancer Driver No 1 hippie 29 55 3 3 0
BCL2L10_ENST00000260442 BCL2L10 Q9HD36 Bcl-2-like protein 10 chr15 Not Cancer Driver No 1 hippie 10 34 1 1 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 115 546 73 73 10
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 Not Cancer Driver No 1 hippie 69 83 9 9 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BIRC5_ENST00000350051 BIRC5 O15392 Baculoviral IAP repeat-containing protein 5 chr17 Not Cancer Driver No 1 hippie 20 49 6 6 0
BIRC6 BIRC6 Q9NR09 Baculoviral IAP repeat-containing protein 6 chr2 Census, Compendium Yes 1 hippie 640 1312 170 170 0
BIRC7 BIRC7 Q96CA5 Baculoviral IAP repeat-containing protein 7 chr20 Not Cancer Driver No 1 hippie 52 136 22 22 0
BIRC8 BIRC8 Q96P09 Baculoviral IAP repeat-containing protein 8 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 79 39 10 10 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 hippie 42 212 19 19 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 Not Cancer Driver No 1 hippie 81 46 11 11 0
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 53 126 7 7 1
CASP10_ENST00000272879 CASP10 Q92851 Caspase-10 chr2 Not Cancer Driver No 1 hippie 57 126 17 17 3
CASP3 CASP3 P42574 Caspase-3 chr4 Census Yes 1 hippie 32 62 5 5 0
CASP7_ENST00000345633 CASP7 P55210 Caspase-7 chr10 Not Cancer Driver No 1 hippie 38 73 10 10 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 Census, Compendium Yes 1 hippie 142 106 12 12 1
CASP9 CASP9 P55211 Caspase-9 chr1 Census Yes 1 hippie 49 71 7 7 0
CFL1_ENST00000308162 CFL1 P23528 Cofilin-1 chr11 Not Cancer Driver No 1 hippie 21 4 0 0 0
CRYAB_ENST00000616970 CRYAB P02511 Alpha-crystallin B chain chr11 Not Cancer Driver No 1 hippie 22 59 11 11 4
CYCS_ENST00000409409 CYCS P99999 Cytochrome c chr7 Not Cancer Driver No 1 hippie 12 19 3 3 1
DCC DCC P43146 Netrin receptor DCC chr18 Census, Compendium Yes 1 hippie 530 631 215 215 2
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 Not Cancer Driver No 1 hippie 62 54 8 8 1
DSP DSP P15924 Desmoplakin chr6 Not Cancer Driver No 1 hippie 483 1124 204 204 6
EIF4A1 EIF4A1 P60842 Eukaryotic initiation factor 4A-I chr17 Not Cancer Driver No 1 hippie 48 35 7 7 0
GMEB1 GMEB1 Q9Y692 Glucocorticoid modulatory element-binding protein 1 chr1 Not Cancer Driver No 1 hippie 56 312 31 31 0
GZMB GZMB P10144 Granzyme B chr14 Not Cancer Driver No 1 hippie 49 103 23 23 0
HECTD3 HECTD3 Q5T447 E3 ubiquitin-protein ligase HECTD3 chr1 Not Cancer Driver No 1 hippie 88 55 5 5 0
HIP1 HIP1 O00291 Huntingtin-interacting protein 1 chr7 Census, Compendium Yes 1 hippie 137 510 70 70 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 Not Cancer Driver No 1 hippie 25 203 20 20 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX Not Cancer Driver No 1 hippie 22 3 0 0 62
HSD17B4_ENST00000256216 HSD17B4 P51659 Peroxisomal multifunctional enzyme type 2 chr5 Not Cancer Driver No 1 hippie 99 82 12 12 4
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 20
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 61 82 6 6 2
HTRA4 HTRA4 P83105 Serine protease HTRA4 chr8 Not Cancer Driver No 1 hippie 57 15 0 0 0
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie 45 71 9 9 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 95 84 12 12 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 Census, Compendium Yes 1 hippie 94 96 24 24 6
MAP2K2 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 Census Yes 1 hippie 58 105 14 14 4
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 62 2 0 0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 38 49 5 5 0
MSTO1 MSTO1 Q9BUK6 Protein misato homolog 1 chr1 Not Cancer Driver No 1 hippie 40 82 4 4 1
NAIP_ENST00000194097 NAIP Q13075 Baculoviral IAP repeat-containing protein 1 chr5 Not Cancer Driver No 1 hippie 39 67 4 4 0
NLRP1_ENST00000572272 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 Not Cancer Driver No 1 hippie 222 340 65 65 6
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie 130 38 7 7 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 hippie 61 79 15 15 1
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 hippie 70 116 11 11 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 Census, Compendium Yes 1 hippie 243 382 67 67 18
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 Census, Compendium Yes 1 hippie 140 282 32 32 22
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
RNF34_ENST00000361234 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 Not Cancer Driver No 1 hippie 30 112 7 7 0
RNPEP RNPEP Q9H4A4 Aminopeptidase B chr1 Not Cancer Driver No 1 hippie 60 86 4 4 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 Not Cancer Driver No 1 hippie 177 34 8 8 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
SRF SRF P11831 Serum response factor chr6 Not Cancer Driver No 1 hippie 44 443 42 42 0
TRIM72 TRIM72 Q6ZMU5 Tripartite motif-containing protein 72 chr16 Not Cancer Driver No 1 hippie 54 69 14 14 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie 84 316 57 57 1
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX Not Cancer Driver No 1 hippie 89 55 6 6 0