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CAPZB_ENST00000375142 ,CAPZB ,P47756
  • Uniprot Accession= P47756
  • Ensembl Transcript= ENST00000375142.5
  • Uniprot Name= CAPZB
  • Name= F-actin-capping protein subunit beta
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 60
  • Number of Interaction partner in biogrid: 84
  • Number of Interaction partner in hippie: 254
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ABRA ABRA Q8N0Z2 Actin-binding Rho-activating protein chr8 Not Cancer Driver No 1 hippie, biogrid 108 285 86 86 0
ACO2 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 Not Cancer Driver No 1 hippie 94 172 19 19 5
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 2 intact, hippie 112 43 5 5 5
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ACTR10 ACTR10 Q9NZ32 Actin-related protein 10 chr14 Not Cancer Driver No 1 hippie, biogrid 45 29 3 3 0
ACTR1A ACTR1A P61163 Alpha-centractin chr10 Not Cancer Driver No 1 hippie, biogrid 47 14 0 0 0
ACTR1B ACTR1B P42025 Beta-centractin chr2 Not Cancer Driver No 2 intact, hippie, biogrid 59 17 4 4 0
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
AHCY AHCY P23526 Adenosylhomocysteinase chr20 Not Cancer Driver No 1 hippie 58 0 0 0 4
AKT3_ENST00000366539 AKT3 Q9Y243 RAC-gamma serine/threonine-protein kinase chr1 Census, Compendium Yes 1 intact, hippie 92 131 24 24 3
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 intact, hippie 144 767 104 104 2
ANO7 ANO7 Q6IWH7 Anoctamin-7 chr2 Not Cancer Driver No 1 hippie 144 147 32 32 0
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARAP1 ARAP1 Q96P48 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 152 401 28 28 0
ARHGAP17 ARHGAP17 Q68EM7 Rho GTPase-activating protein 17 chr16 Not Cancer Driver No 1 hippie 123 547 72 72 0
ARPC2_ENST00000315717 ARPC2 O15144 Actin-related protein 2/3 complex subunit 2 chr2 Not Cancer Driver No 1 hippie, biogrid 40 49 8 8 0
ARPC3 ARPC3 O15145 Actin-related protein 2/3 complex subunit 3 chr12 Not Cancer Driver No 1 hippie, biogrid 17 26 6 6 0
ARPC5L ARPC5L Q9BPX5 Actin-related protein 2/3 complex subunit 5-like protein chr9 Not Cancer Driver No 1 hippie, biogrid 4 48 0 0 0
ARPC5_ENST00000359856 ARPC5 O15511 Actin-related protein 2/3 complex subunit 5 chr1 Not Cancer Driver No 1 hippie, biogrid 15 66 7 7 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 biogrid 29 195 9 9 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 hippie 37 63 7 7 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BCCIP_ENST00000278100 BCCIP Q9P287 BRCA2 and CDKN1A-interacting protein chr10 Not Cancer Driver No 1 hippie, biogrid 35 99 16 16 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 Not Cancer Driver No 1 hippie 29 55 3 3 0
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 Not Cancer Driver No 1 hippie 124 656 86 86 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 115 546 73 73 10
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BLNK BLNK Q8WV28 B-cell linker protein chr10 Not Cancer Driver No 1 hippie 74 376 61 61 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 2 intact, hippie 50 150 30 30 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 2 hippie, biogrid 27 192 24 24 0
CAPZA1 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 Not Cancer Driver No 8 intact, hippie, biogrid 40 41 2 2 0
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 5 hippie, biogrid 37 19 0 0 0
CARMIL1 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 Not Cancer Driver No 1 hippie 171 537 87 87 0
CARMIL2 CARMIL2 Q6F5E8 Capping protein, Arp2/3 and myosin-I linker protein 2 chr16 Not Cancer Driver No 1 hippie 154 669 75 75 4
CCDC33_ENST00000558821 CCDC33 Q8N5R6-4 Isoform 4 of Coiled-coil domain-containing protein 33 chr15 Not Cancer Driver No 1 intact, hippie 60 288 51 51 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CD2AP CD2AP Q9Y5K6 CD2-associated protein chr6 Not Cancer Driver No 2 hippie, biogrid 80 456 60 60 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 intact, hippie 39 23 2 2 1
CDC73 CDC73 Q6P1J9 Parafibromin chr1 Census, Compendium Yes 1 hippie 110 210 39 39 2
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie 50 34 2 2 0
CEP152 CEP152 O94986 Centrosomal protein of 152 kDa chr15 Not Cancer Driver No 1 biogrid 204 986 110 110 2
CEP295 CEP295 Q9C0D2 Centrosomal protein of 295 kDa chr11 Not Cancer Driver No 1 biogrid 115 2026 87 87 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 2 intact, hippie 287 145 18 18 151
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 346 464 56 56 12
CNOT10_ENST00000328834 CNOT10 Q9H9A5 CCR4-NOT transcription complex subunit 10 chr3 Not Cancer Driver No 1 hippie, biogrid 69 218 18 18 0
CNOT11 CNOT11 Q9UKZ1 CCR4-NOT transcription complex subunit 11 chr2 Not Cancer Driver No 1 hippie, biogrid 53 216 16 16 0
CNOT2 CNOT2 Q9NZN8 CCR4-NOT transcription complex subunit 2 chr12 Not Cancer Driver No 2 hippie, biogrid 84 354 66 66 0
CNOT3 CNOT3 O75175 CCR4-NOT transcription complex subunit 3 chr19 Census, Compendium Yes 1 hippie, biogrid 120 538 78 78 4
CNOT6L CNOT6L Q96LI5 CCR4-NOT transcription complex subunit 6-like chr4 Not Cancer Driver No 1 hippie, biogrid 58 37 3 3 0
CNOT6_ENST00000261951 CNOT6 Q9ULM6 CCR4-NOT transcription complex subunit 6 chr5 Not Cancer Driver No 1 hippie, biogrid 65 66 4 4 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 Not Cancer Driver No 1 hippie, biogrid 31 21 1 1 0
CNOT8 CNOT8 Q9UFF9 CCR4-NOT transcription complex subunit 8 chr5 Not Cancer Driver No 1 hippie, biogrid 30 6 0 0 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 Compendium Yes 1 hippie 42 30 0 0 0
COX15 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 1 intact, hippie, biogrid 48 0 0 0 2
CPVL_ENST00000265394 CPVL Q9H3G5 Probable serine carboxypeptidase CPVL chr7 Not Cancer Driver No 1 hippie, biogrid 81 0 0 0 0
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 42 123 9 9 1
CTNNBL1 CTNNBL1 Q8WYA6 Beta-catenin-like protein 1 chr20 Not Cancer Driver No 1 biogrid 72 158 24 24 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 193 114 11 11 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 Not Cancer Driver No 1 intact, hippie 84 510 73 73 0
DCAF15 DCAF15 Q66K64 DDB1- and CUL4-associated factor 15 chr19 Not Cancer Driver No 1 hippie 50 173 18 18 0
DCAF4 DCAF4 Q8WV16 DDB1- and CUL4-associated factor 4 chr14 Not Cancer Driver No 1 intact, hippie 59 114 11 11 0
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 Census Yes 5 intact, hippie, biogrid 172 817 111 111 11
DCTN2_ENST00000548249 DCTN2 Q13561 Dynactin subunit 2 chr12 Not Cancer Driver No 2 hippie, biogrid 46 253 32 32 0
DCTN3 DCTN3 O75935 Dynactin subunit 3 chr9 Not Cancer Driver No 1 hippie, biogrid 18 3 0 0 0
DCTN4_ENST00000447998 DCTN4 Q9UJW0 Dynactin subunit 4 chr5 Not Cancer Driver No 2 hippie, biogrid 47 138 18 18 0
DCTN5 DCTN5 Q9BTE1 Dynactin subunit 5 chr16 Not Cancer Driver No 1 hippie, biogrid 23 0 0 0 0
DCTN6 DCTN6 O00399 Dynactin subunit 6 chr8 Not Cancer Driver No 2 hippie, biogrid 25 45 0 0 0
DCTPP1 DCTPP1 Q9H773 dCTP pyrophosphatase 1 chr16 Not Cancer Driver No 1 hippie 14 88 9 9 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 49 34 8 8 0
DDX53 DDX53 Q86TM3 Probable ATP-dependent RNA helicase DDX53 chrX Not Cancer Driver No 1 hippie, biogrid 113 199 42 42 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 67 17 0 0 10
DMWD DMWD Q09019 Dystrophia myotonica WD repeat-containing protein chr19 Not Cancer Driver No 1 hippie, biogrid 66 374 24 24 0
DOK2 DOK2 O60496 Docking protein 2 chr8 Not Cancer Driver No 1 hippie 58 254 31 31 0
DUSP8_ENST00000331588 DUSP8 Q13202 Dual specificity protein phosphatase 8 chr11 Not Cancer Driver No 1 hippie 40 338 11 11 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 135 447 73 73 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 Not Cancer Driver No 1 hippie 50 57 6 6 1
ELK4 ELK4 P28324 ETS domain-containing protein Elk-4 chr1 Census Yes 1 intact, hippie 46 239 26 26 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 Not Cancer Driver No 1 hippie 33 19 0 0 4
FBXO28 FBXO28 Q9NVF7 F-box only protein 28 chr1 Not Cancer Driver No 1 hippie, biogrid 49 230 30 30 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FGD5 FGD5 Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 chr3 Compendium Yes 1 hippie, biogrid 275 915 180 180 0
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 30 0 0 0 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 intact, hippie 416 1456 214 214 28
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 intact, hippie 394 1243 185 185 8
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 11 2 1 1 0
GAK GAK O14976 Cyclin-G-associated kinase chr4 Not Cancer Driver No 1 intact, hippie 146 589 79 79 0
GH1 GH1 P01241 Somatotropin chr17 Not Cancer Driver No 1 intact, hippie 54 24 9 9 15
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 Census, Compendium Yes 1 hippie 206 1015 184 184 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
GRN GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie 76 29 6 6 1
HASPIN HASPIN Q8TF76 Serine/threonine-protein kinase haspin chr17 Not Cancer Driver No 1 intact, hippie 87 373 36 36 0
HECW2_ENST00000644256 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 Not Cancer Driver No 1 hippie 348 845 195 195 4
HEXA_ENST00000268097 HEXA P06865 Beta-hexosaminidase subunit alpha chr15 Not Cancer Driver No 1 hippie 59 5 1 1 49
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HIST1H2BH H2BC9 Q93079 Histone H2B type 1-H chr6 Not Cancer Driver No 1 intact 42 79 20 20 0
HOOK3 HOOK3 Q86VS8 Protein Hook homolog 3 chr8 Census Yes 1 hippie 79 493 55 55 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 intact, hippie 108 76 13 13 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 intact, hippie 183 351 35 35 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 254 97 27 27 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
JUP JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 1 hippie 112 241 37 37 0
KIAA1671_ENST00000406486 KIAA1671 Q9BY89 Uncharacterized protein KIAA1671 chr22 Not Cancer Driver No 1 hippie, biogrid 14 1759 14 14 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 788 7 2 2 27
L1TD1 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie 149 534 114 114 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 biogrid 74 611 69 69 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie 88 687 81 81 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MAGOH MAGOH P61326 Protein mago nashi homolog chr1 Not Cancer Driver No 1 hippie 15 6 0 0 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 intact, hippie 10 17 1 1 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 74 355 44 44 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 1 hippie 39 25 1 1 0
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 Compendium Yes 2 hippie, biogrid 124 445 70 70 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 hippie 92 376 49 49 1
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX Not Cancer Driver No 1 biogrid 63 16 4 4 9
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact, hippie 136 589 92 92 0
MCFD2_ENST00000409973 MCFD2 Q8NI22 Multiple coagulation factor deficiency protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 16 90 11 11 4
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MDC1 MDC1 Q14676 Mediator of DNA damage checkpoint protein 1 chr6 Not Cancer Driver No 1 hippie 249 1829 223 223 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie, biogrid 76 446 42 42 0
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 113 740 56 56 0
MOSPD2 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX Not Cancer Driver No 1 intact 58 143 16 16 0
MRPL20 MRPL20 Q9BYC9 39S ribosomal protein L20, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie, biogrid 20 0 0 0 0
MTCL1_ENST00000306329 MTCL1 Q9Y4B5 Microtubule cross-linking factor 1 chr18 Not Cancer Driver No 1 hippie, biogrid 267 1681 232 232 0
MTPN MTPN P58546 Myotrophin chr7 Not Cancer Driver No 3 intact, hippie, biogrid 11 11 3 3 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYH11_ENST00000300036 MYH11 P35749 Myosin-11 chr16 Census, Compendium Yes 1 hippie 353 1180 201 201 2
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 310 1120 160 160 17
MYLK MYLK Q15746 Myosin light chain kinase, smooth muscle chr3 Not Cancer Driver No 1 intact, hippie, biogrid 343 957 184 184 3
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie 268 1237 176 176 0
MYO5B MYO5B Q9ULV0 Unconventional myosin-Vb chr18 Not Cancer Driver No 1 hippie, biogrid 269 505 68 68 14
MYO5C MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 intact, hippie 204 394 43 43 0
NAPA NAPA P54920 Alpha-soluble NSF attachment protein chr19 Not Cancer Driver No 1 hippie, biogrid 33 11 0 0 0
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 Not Cancer Driver No 1 intact 88 89 8 8 0
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 123 117 42 42 0
NDUFA7 NDUFA7 O95182 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 chr19 Not Cancer Driver No 1 hippie 16 103 13 13 0
NFX1 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 Not Cancer Driver No 1 hippie 121 491 46 46 0
NIN NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 239 1392 164 164 2
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 230 881 150 150 0
NMRAL1 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 39 14 3 3 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUDCD2 NUDCD2 Q8WVJ2 NudC domain-containing protein 2 chr5 Not Cancer Driver No 1 hippie 12 39 6 6 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX Not Cancer Driver No 1 hippie 151 126 24 24 41
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 Not Cancer Driver No 1 biogrid 42 82 11 11 7
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PAPSS1 PAPSS1 O43252 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 chr4 Not Cancer Driver No 1 hippie 94 82 14 14 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 Not Cancer Driver No 1 hippie 120 461 39 39 0
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 Not Cancer Driver No 1 hippie, biogrid 46 13 5 5 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PDLIM7 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 Not Cancer Driver No 1 hippie 48 244 20 20 0
PER2 PER2 O15055 Period circadian protein homolog 2 chr2 Not Cancer Driver No 1 hippie 166 782 101 101 1
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PIM3 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 24 9 0 0 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHO1 PLEKHO1 Q53GL0 Pleckstrin homology domain-containing family O member 1 chr1 Not Cancer Driver No 2 hippie, biogrid 55 341 46 46 0
PLEKHO2 PLEKHO2 Q8TD55 Pleckstrin homology domain-containing family O member 2 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 61 402 56 56 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 hippie 38 27 6 6 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 1 intact, hippie 47 25 5 5 5
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 intact, hippie 26 23 4 4 0
PPP1R9A_ENST00000433881 PPP1R9A Q9ULJ8 Neurabin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 217 887 174 174 0
PPP2R2B_ENST00000394409 PPP2R2B Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform chr5 Not Cancer Driver No 1 hippie 101 76 22 22 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 Not Cancer Driver No 1 hippie 37 0 0 0 23
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PRNP PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 36 115 7 7 18
PSMC1 PSMC1 P62191 26S proteasome regulatory subunit 4 chr14 Not Cancer Driver No 1 biogrid 36 165 10 10 0
PSME3_ENST00000590720 PSME3 P61289 Proteasome activator complex subunit 3 chr17 Not Cancer Driver No 1 hippie 20 25 5 5 0
PTN PTN P21246 Pleiotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 43 51 11 11 0
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie 59 328 43 43 0
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 Compendium Yes 1 hippie 154 181 25 25 3
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 158 796 115 115 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 Not Cancer Driver No 1 hippie 128 703 81 81 0
RCSD1 RCSD1 Q6JBY9 CapZ-interacting protein chr1 Not Cancer Driver No 2 hippie, biogrid 70 416 70 70 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RHOBTB2_ENST00000251822 RHOBTB2 Q9BYZ6 Rho-related BTB domain-containing protein 2 chr8 Not Cancer Driver No 1 hippie 99 131 18 18 6
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 20 10 0 0 0
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 18 10 0 0 0
RHOV RHOV Q96L33 Rho-related GTP-binding protein RhoV chr15 Not Cancer Driver No 1 hippie 25 47 5 5 0
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact, hippie 137 417 61 61 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 Not Cancer Driver No 1 intact, hippie 66 295 39 39 0
RND3_ENST00000263895 RND3 P61587 Rho-related GTP-binding protein RhoE chr2 Not Cancer Driver No 1 hippie 36 70 10 10 0
RNF138 RNF138 Q8WVD3 E3 ubiquitin-protein ligase RNF138 chr18 Not Cancer Driver No 1 hippie 44 34 6 6 0
RNF169 RNF169 Q8NCN4 E3 ubiquitin-protein ligase RNF169 chr11 Not Cancer Driver No 1 hippie 52 637 46 46 0
RPAP3 RPAP3 Q9H6T3 RNA polymerase II-associated protein 3 chr12 Not Cancer Driver No 1 hippie, biogrid 59 334 37 37 0
RPGRIP1L_ENST00000379925 RPGRIP1L Q68CZ1 Protein fantom chr16 Not Cancer Driver No 1 intact, hippie 177 586 94 94 8
RPL36A_ENST00000553110 RPL36A P83881 60S ribosomal protein L36a chrX Not Cancer Driver No 1 biogrid 17 64 10 10 0
RPP14_ENST00000295959 RPP14 O95059 Ribonuclease P protein subunit p14 chr3 Not Cancer Driver No 1 intact, hippie 8 0 0 0 0
SCARB2 SCARB2 Q14108 Lysosome membrane protein 2 chr4 Not Cancer Driver No 1 hippie 61 13 3 3 1
SERPINA5_ENST00000554276 SERPINA5 P05154 Plasma serine protease inhibitor chr14 Not Cancer Driver No 1 hippie 103 24 17 17 0
SH3BGRL SH3BGRL O75368 SH3 domain-binding glutamic acid-rich-like protein chrX Not Cancer Driver No 1 intact, hippie 23 51 8 8 0
SH3BP1 SH3BP1 Q9Y3L3 SH3 domain-binding protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 57 430 31 31 0
SH3KBP1 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 4 intact, hippie, biogrid 102 530 82 82 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 Census, Compendium Yes 1 hippie 96 281 51 51 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 33 164 12 12 0
SLC25A1 SLC25A1 P53007 Tricarboxylate transport protein, mitochondrial chr22 Not Cancer Driver No 1 hippie 22 34 2 2 17
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 66 103 18 18 0
SVIL SVIL O95425 Supervillin chr10 Not Cancer Driver No 1 hippie, biogrid 308 1423 192 192 0
SYNPO SYNPO Q8N3V7 Synaptopodin chr5 Not Cancer Driver No 1 intact, hippie 103 918 102 102 0
TAF2 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 Not Cancer Driver No 1 biogrid 129 241 34 34 1
TBCK_ENST00000432496 TBCK Q8TEA7 TBC domain-containing protein kinase-like protein chr4 Not Cancer Driver No 1 intact, hippie, biogrid 115 88 9 9 2
TES TES Q9UGI8 Testin chr7 Not Cancer Driver No 1 hippie 56 100 7 7 0
TIAF1 MYO18A O95411 Putative TGFB1-induced anti-apoptotic factor 1 chr17 Not Cancer Driver No 1 hippie 16 30 5 5 0
TMOD3 TMOD3 Q9NYL9 Tropomodulin-3 chr15 Not Cancer Driver No 1 hippie, biogrid 40 190 24 24 0
TNKS1BP1 TNKS1BP1 Q9C0C2 182 kDa tankyrase-1-binding protein chr11 Not Cancer Driver No 2 intact, hippie, biogrid 221 1712 219 219 0
TOMM40_ENST00000405636 TOMM40 O96008 Mitochondrial import receptor subunit TOM40 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 17 98 1 1 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 hippie 227 1632 190 190 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TPM2 TPM2 P07951 Tropomyosin beta chain chr9 Not Cancer Driver No 1 hippie, biogrid 39 232 35 35 15
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 intact, hippie 67 62 7 7 0
TRIM14 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 Not Cancer Driver No 1 hippie 36 93 7 7 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 intact 59 52 11 11 8
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 hippie 67 53 10 10 12
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 50 52 3 3 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 Not Cancer Driver No 1 hippie, biogrid 34 59 8 8 0
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 1 hippie 78 191 28 28 0
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 biogrid 84 219 33 33 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UBE2Q2 UBE2Q2 Q8WVN8 Ubiquitin-conjugating enzyme E2 Q2 chr15 Not Cancer Driver No 1 hippie 35 122 10 10 0
UBL7_ENST00000565335 UBL7 Q96S82 Ubiquitin-like protein 7 chr15 Not Cancer Driver No 1 hippie, biogrid 31 192 22 22 0
UBR5 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 Census, Compendium Yes 1 hippie 340 1296 162 162 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
UIMC1_ENST00000511320 UIMC1 Q96RL1 BRCA1-A complex subunit RAP80 chr5 Not Cancer Driver No 1 hippie, biogrid 64 609 51 51 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 59 86 6 6 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 2 intact, hippie 188 110 28 28 0
VCL VCL P18206 Vinculin chr10 Not Cancer Driver No 1 hippie 114 673 80 80 2
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 142 117 36 36 133
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VMP1 VMP1 Q96GC9 Vacuole membrane protein 1 chr17 Not Cancer Driver No 1 hippie 57 68 11 11 0
VPS26A_ENST00000263559 VPS26A O75436 Vacuolar protein sorting-associated protein 26A chr10 Not Cancer Driver No 1 intact, hippie 27 44 2 2 0
WASHC2A WASHC2A Q641Q2 WASH complex subunit 2A chr10 Not Cancer Driver No 1 hippie 48 1222 42 42 0
WASHC2C_ENST00000374362 WASHC2C Q9Y4E1 WASH complex subunit 2C chr10 Not Cancer Driver No 1 hippie 90 1204 89 89 0
WASHC3 WASHC3 Q9Y3C0 WASH complex subunit 3 chr12 Not Cancer Driver No 1 hippie 29 100 8 8 0
WASHC4_ENST00000332180 WASHC4 Q2M389 WASH complex subunit 4 chr12 Not Cancer Driver No 1 hippie 132 49 1 1 1
WASHC5 WASHC5 Q12768 WASH complex subunit 5 chr8 Not Cancer Driver No 1 intact, hippie 152 23 6 6 6
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 Not Cancer Driver No 1 biogrid 129 427 63 63 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
ZBTB18_ENST00000622512 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 78 236 25 25 0
ZNF574_ENST00000359044 ZNF574 Q6ZN55 Zinc finger protein 574 chr19 Not Cancer Driver No 1 biogrid 120 410 51 51 0