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CAPZA1 ,CAPZA1 ,P52907
  • Uniprot Accession= P52907
  • Ensembl Transcript= ENST00000263168.3
  • Uniprot Name= CAPZA1
  • Name= F-actin-capping protein subunit alpha-1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 61
  • Number of Interaction partner in biogrid: 65
  • Number of Interaction partner in hippie: 243
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAK1 AAK1 Q2M2I8 AP2-associated protein kinase 1 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 109 654 70 70 0
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 2 intact, hippie 112 43 5 5 5
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ACTR10 ACTR10 Q9NZ32 Actin-related protein 10 chr14 Not Cancer Driver No 1 hippie, biogrid 45 29 3 3 0
ACTR1A ACTR1A P61163 Alpha-centractin chr10 Not Cancer Driver No 1 hippie, biogrid 47 14 0 0 0
ACTR1B ACTR1B P42025 Beta-centractin chr2 Not Cancer Driver No 1 hippie, biogrid 59 17 4 4 0
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 51 6 2 2 0
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 intact, hippie 144 767 104 104 2
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARAP1 ARAP1 Q96P48 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 152 401 28 28 0
ARHGAP1 ARHGAP1 Q07960 Rho GTPase-activating protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 39 90 8 8 0
ARHGAP17 ARHGAP17 Q68EM7 Rho GTPase-activating protein 17 chr16 Not Cancer Driver No 1 hippie 123 547 72 72 0
ARPC2_ENST00000315717 ARPC2 O15144 Actin-related protein 2/3 complex subunit 2 chr2 Not Cancer Driver No 1 hippie, biogrid 40 49 8 8 0
ARPC3 ARPC3 O15145 Actin-related protein 2/3 complex subunit 3 chr12 Not Cancer Driver No 1 hippie, biogrid 17 26 6 6 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 Not Cancer Driver No 1 hippie 46 122 22 22 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 Not Cancer Driver No 1 hippie 23 118 14 14 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 40 25 6 6 1
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 hippie 37 63 7 7 0
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 Not Cancer Driver No 1 hippie 124 656 86 86 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 115 546 73 73 10
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BLNK BLNK Q8WV28 B-cell linker protein chr10 Not Cancer Driver No 1 hippie 74 376 61 61 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
CAPZA1 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 Not Cancer Driver No 1 intact, hippie 40 41 2 2 0
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 4 hippie, biogrid 37 19 0 0 0
CAPZB_ENST00000375142 CAPZB P47756 F-actin-capping protein subunit beta chr1 Not Cancer Driver No 8 intact, hippie, biogrid 33 66 3 3 0
CARMIL1 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 Not Cancer Driver No 2 intact, hippie 171 537 87 87 0
CARMIL2 CARMIL2 Q6F5E8 Capping protein, Arp2/3 and myosin-I linker protein 2 chr16 Not Cancer Driver No 1 hippie 154 669 75 75 4
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 hippie 115 512 56 56 4
CCNA1 CCNA1 P78396 Cyclin-A1 chr13 Not Cancer Driver No 1 intact, hippie 112 82 21 21 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CD2AP CD2AP Q9Y5K6 CD2-associated protein chr6 Not Cancer Driver No 4 intact, hippie, biogrid 80 456 60 60 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 intact, hippie 39 23 2 2 1
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 100 618 77 77 0
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie 50 34 2 2 0
CDKL2_ENST00000429927 CDKL2 Q92772 Cyclin-dependent kinase-like 2 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 63 171 21 21 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 2 intact, hippie 287 145 18 18 151
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CHUK CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 Not Cancer Driver No 1 intact, hippie 74 116 9 9 0
CIAPIN1 CIAPIN1 Q6FI81 Anamorsin chr16 Not Cancer Driver No 1 hippie 27 119 8 8 0
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CLTA CLTA P09496 Clathrin light chain A chr9 Not Cancer Driver No 1 hippie, biogrid 20 192 12 12 0
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 346 464 56 56 12
CNOT10_ENST00000328834 CNOT10 Q9H9A5 CCR4-NOT transcription complex subunit 10 chr3 Not Cancer Driver No 1 hippie, biogrid 69 218 18 18 0
CNOT11 CNOT11 Q9UKZ1 CCR4-NOT transcription complex subunit 11 chr2 Not Cancer Driver No 1 hippie, biogrid 53 216 16 16 0
CNOT2 CNOT2 Q9NZN8 CCR4-NOT transcription complex subunit 2 chr12 Not Cancer Driver No 1 hippie, biogrid 84 354 66 66 0
CNOT3 CNOT3 O75175 CCR4-NOT transcription complex subunit 3 chr19 Census, Compendium Yes 1 hippie, biogrid 120 538 78 78 4
CNOT6L CNOT6L Q96LI5 CCR4-NOT transcription complex subunit 6-like chr4 Not Cancer Driver No 1 hippie, biogrid 58 37 3 3 0
CNOT6_ENST00000261951 CNOT6 Q9ULM6 CCR4-NOT transcription complex subunit 6 chr5 Not Cancer Driver No 1 hippie, biogrid 65 66 4 4 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 Not Cancer Driver No 1 hippie, biogrid 31 21 1 1 0
CNOT8 CNOT8 Q9UFF9 CCR4-NOT transcription complex subunit 8 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 30 6 0 0 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 Compendium Yes 1 hippie 42 30 0 0 0
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 42 123 9 9 1
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 193 114 11 11 0
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 Census Yes 3 intact, hippie, biogrid 172 817 111 111 11
DCTN2_ENST00000548249 DCTN2 Q13561 Dynactin subunit 2 chr12 Not Cancer Driver No 2 hippie, biogrid 46 253 32 32 0
DCTN3 DCTN3 O75935 Dynactin subunit 3 chr9 Not Cancer Driver No 1 hippie, biogrid 18 3 0 0 0
DCTN4_ENST00000447998 DCTN4 Q9UJW0 Dynactin subunit 4 chr5 Not Cancer Driver No 2 hippie, biogrid 47 138 18 18 0
DCTN5 DCTN5 Q9BTE1 Dynactin subunit 5 chr16 Not Cancer Driver No 1 hippie, biogrid 23 0 0 0 0
DCTN6 DCTN6 O00399 Dynactin subunit 6 chr8 Not Cancer Driver No 1 hippie, biogrid 25 45 0 0 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DOK2 DOK2 O60496 Docking protein 2 chr8 Not Cancer Driver No 1 hippie 58 254 31 31 0
DPF2_ENST00000528416 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 Not Cancer Driver No 1 hippie 67 179 30 30 5
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF1B EIF1B O60739 Eukaryotic translation initiation factor 1b chr3 Not Cancer Driver No 1 hippie 12 6 0 0 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 Not Cancer Driver No 1 hippie 50 57 6 6 1
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ELK4 ELK4 P28324 ETS domain-containing protein Elk-4 chr1 Census Yes 1 intact, hippie 46 239 26 26 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 intact, hippie 90 92 11 11 1
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 30 0 0 0 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 intact, hippie 416 1456 214 214 28
FLNB_ENST00000295956 FLNB O75369 Filamin-B chr3 Not Cancer Driver No 1 hippie 362 1183 170 170 19
FLNC FLNC Q14315 Filamin-C chr7 Not Cancer Driver No 1 hippie 546 1442 288 288 7
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 intact, hippie 394 1243 185 185 8
FRK FRK P42685 Tyrosine-protein kinase FRK chr6 Not Cancer Driver No 1 hippie, biogrid 87 18 2 2 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 1 hippie 216 669 76 76 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie 86 110 26 26 50
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
GRN GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie 76 29 6 6 1
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie 56 146 13 13 0
HASPIN HASPIN Q8TF76 Serine/threonine-protein kinase haspin chr17 Not Cancer Driver No 1 intact, hippie 87 373 36 36 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 Compendium Yes 1 hippie 78 169 34 34 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HOOK1 HOOK1 Q9UJC3 Protein Hook homolog 1 chr1 Not Cancer Driver No 1 hippie 97 427 59 59 0
HOOK3 HOOK3 Q86VS8 Protein Hook homolog 3 chr8 Census Yes 1 hippie 79 493 55 55 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 intact, hippie 108 76 13 13 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 intact, hippie 6 301 6 6 22
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 254 97 27 27 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KDM4A KDM4A O75164 Lysine-specific demethylase 4A chr1 Not Cancer Driver No 1 hippie, biogrid 122 337 44 44 0
KIAA1671_ENST00000406486 KIAA1671 Q9BY89 Uncharacterized protein KIAA1671 chr22 Not Cancer Driver No 1 hippie, biogrid 14 1759 14 14 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
L1TD1 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie 149 534 114 114 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie 88 687 81 81 0
LRRFIP2 LRRFIP2 Q9Y608 Leucine-rich repeat flightless-interacting protein 2 chr3 Not Cancer Driver No 1 hippie, biogrid 75 584 62 62 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MAGOH MAGOH P61326 Protein mago nashi homolog chr1 Not Cancer Driver No 1 hippie 15 6 0 0 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 74 355 44 44 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 104 333 66 66 6
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 Not Cancer Driver No 1 hippie 26 109 11 11 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 Compendium Yes 2 hippie, biogrid 124 445 70 70 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 hippie 92 376 49 49 1
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact, hippie 136 589 92 92 0
MCFD2_ENST00000409973 MCFD2 Q8NI22 Multiple coagulation factor deficiency protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 16 90 11 11 4
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MDC1 MDC1 Q14676 Mediator of DNA damage checkpoint protein 1 chr6 Not Cancer Driver No 1 hippie 249 1829 223 223 0
MPG MPG P29372 DNA-3-methyladenine glycosylase chr16 Not Cancer Driver No 1 hippie 35 141 21 21 0
MTCL1_ENST00000306329 MTCL1 Q9Y4B5 Microtubule cross-linking factor 1 chr18 Not Cancer Driver No 1 hippie, biogrid 267 1681 232 232 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 310 1120 160 160 17
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie 268 1237 176 176 0
MYO5C MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 2 intact, hippie, biogrid 204 394 43 43 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 Not Cancer Driver No 1 hippie 176 342 41 41 3
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NCAPD3 NCAPD3 P42695 Condensin-2 complex subunit D3 chr11 Not Cancer Driver No 1 hippie 193 304 42 42 1
NEB_ENST00000172853 NEB P20929 Nebulin chr2 Not Cancer Driver No 1 intact, hippie 1188 1984 355 355 0
NEK2 NEK2 P51955 Serine/threonine-protein kinase Nek2 chr1 Not Cancer Driver No 1 hippie 61 92 19 19 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 78 492 49 49 0
NIN NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 239 1392 164 164 2
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 230 881 150 150 0
NLRP9 NLRP9 Q7RTR0 NACHT, LRR and PYD domains-containing protein 9 chr19 Not Cancer Driver No 1 hippie, biogrid 247 0 0 0 0
NMRAL1 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 39 14 3 3 0
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 155 24 0 0 150
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUDCD2 NUDCD2 Q8WVJ2 NudC domain-containing protein 2 chr5 Not Cancer Driver No 1 hippie 12 39 6 6 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX Not Cancer Driver No 1 hippie 151 126 24 24 41
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 Not Cancer Driver No 1 hippie 120 461 39 39 0
PCDH7_ENST00000361762 PCDH7 O60245 Protocadherin-7 chr4 Not Cancer Driver No 1 intact, hippie 167 550 76 76 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PIM3 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 24 9 0 0 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 152 919 121 121 0
PLEKHO1 PLEKHO1 Q53GL0 Pleckstrin homology domain-containing family O member 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 55 341 46 46 0
PLEKHO2 PLEKHO2 Q8TD55 Pleckstrin homology domain-containing family O member 2 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 61 402 56 56 0
PLS1 PLS1 Q14651 Plastin-1 chr3 Not Cancer Driver No 1 hippie, biogrid 100 59 8 8 4
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 hippie 38 27 6 6 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 1 intact, hippie 47 25 5 5 5
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 hippie 26 23 4 4 0
PPP2R2B_ENST00000394409 PPP2R2B Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform chr5 Not Cancer Driver No 2 intact, hippie 101 76 22 22 0
PRKAB1 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 Not Cancer Driver No 1 intact, hippie 39 124 13 13 0
PRNP PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 36 115 7 7 18
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PRPH PRPH P41219 Peripherin chr12 Not Cancer Driver No 1 hippie, biogrid 37 239 20 20 0
PSMA1_ENST00000396394 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 Not Cancer Driver No 1 hippie, biogrid 48 51 9 9 0
PSMA6 PSMA6 P60900 Proteasome subunit alpha type-6 chr14 Not Cancer Driver No 1 hippie, biogrid 37 2 1 1 0
PSMB6 PSMB6 P28072 Proteasome subunit beta type-6 chr17 Not Cancer Driver No 1 hippie, biogrid 19 22 1 1 0
PSME3_ENST00000590720 PSME3 P61289 Proteasome activator complex subunit 3 chr17 Not Cancer Driver No 1 hippie 20 25 5 5 0
PSMG1 PSMG1 O95456 Proteasome assembly chaperone 1 chr21 Not Cancer Driver No 1 hippie 31 25 1 1 0
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie 59 328 43 43 0
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 Compendium Yes 1 hippie 154 181 25 25 3
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 Not Cancer Driver No 1 hippie 128 703 81 81 0
RCSD1 RCSD1 Q6JBY9 CapZ-interacting protein chr1 Not Cancer Driver No 2 hippie, biogrid 70 416 70 70 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 Not Cancer Driver No 1 intact, hippie 66 295 39 39 0
RNF169 RNF169 Q8NCN4 E3 ubiquitin-protein ligase RNF169 chr11 Not Cancer Driver No 1 hippie 52 637 46 46 0
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 51 98 6 6 0
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie 28 114 16 16 0
RPA3 RPA3 P35244 Replication protein A 14 kDa subunit chr7 Not Cancer Driver No 1 hippie 13 4 1 1 0
RPGRIP1L_ENST00000379925 RPGRIP1L Q68CZ1 Protein fantom chr16 Not Cancer Driver No 1 intact, hippie 177 586 94 94 8
RPS6KB2 RPS6KB2 Q9UBS0 Ribosomal protein S6 kinase beta-2 chr11 Not Cancer Driver No 1 hippie 54 194 16 16 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 1 intact, hippie 74 513 48 48 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 Compendium Yes 1 hippie 90 184 26 26 0
S100A1 S100A1 P23297 Protein S100-A1 chr1 Not Cancer Driver No 1 hippie 13 9 0 0 0
S100A5 S100A5 P33763 Protein S100-A5 chr1 Not Cancer Driver No 1 hippie 12 7 1 1 0
S100B S100B P04271 Protein S100-B chr21 Not Cancer Driver No 2 intact, hippie 17 13 1 1 0
S100P S100P P25815 Protein S100-P chr4 Not Cancer Driver No 1 hippie 7 3 1 1 0
SCARB2 SCARB2 Q14108 Lysosome membrane protein 2 chr4 Not Cancer Driver No 1 hippie 61 13 3 3 1
SF3B1 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 Census, Compendium Yes 1 hippie, biogrid 244 477 80 80 0
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 Not Cancer Driver No 1 hippie 38 159 23 23 0
SH3BGRL SH3BGRL O75368 SH3 domain-binding glutamic acid-rich-like protein chrX Not Cancer Driver No 1 intact, hippie 23 51 8 8 0
SH3BP1 SH3BP1 Q9Y3L3 SH3 domain-binding protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 57 430 31 31 0
SH3KBP1 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 5 intact, hippie, biogrid 102 530 82 82 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 33 164 12 12 0
SMURF1 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 Not Cancer Driver No 2 hippie, biogrid 89 256 31 31 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 62 488 56 56 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 66 103 18 18 0
STRAP STRAP Q9Y3F4 Serine-threonine kinase receptor-associated protein chr12 Not Cancer Driver No 1 hippie 44 40 5 5 0
SULT1C3 SULT1C3 Q6IMI6 Sulfotransferase 1C3 chr2 Not Cancer Driver No 1 hippie, biogrid 77 14 5 5 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SVIL SVIL O95425 Supervillin chr10 Not Cancer Driver No 1 hippie, biogrid 308 1423 192 192 0
TBCK_ENST00000432496 TBCK Q8TEA7 TBC domain-containing protein kinase-like protein chr4 Not Cancer Driver No 1 intact, hippie, biogrid 115 88 9 9 2
TEX101_ENST00000598265 TEX101 Q9BY14 Testis-expressed protein 101 chr19 Not Cancer Driver No 1 intact, hippie 45 2 0 0 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 68 169 23 23 0
TIAF1 MYO18A O95411 Putative TGFB1-induced anti-apoptotic factor 1 chr17 Not Cancer Driver No 1 hippie 16 30 5 5 0
TIFAB TIFAB Q6ZNK6 TRAF-interacting protein with FHA domain-containing protein B chr5 Not Cancer Driver No 1 intact, hippie 32 26 7 7 0
TNF TNF P01375 Tumor necrosis factor chr6 Not Cancer Driver No 1 hippie 24 45 3 3 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TNKS1BP1 TNKS1BP1 Q9C0C2 182 kDa tankyrase-1-binding protein chr11 Not Cancer Driver No 2 intact, hippie, biogrid 221 1712 219 219 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 hippie 227 1632 190 190 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 intact, hippie 67 62 7 7 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 intact, hippie 59 52 11 11 8
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 hippie 67 53 10 10 12
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 50 52 3 3 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 Not Cancer Driver No 1 hippie, biogrid 34 59 8 8 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UBR5 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 Census, Compendium Yes 1 hippie 340 1296 162 162 0
UCHL5 UCHL5 Q9Y5K5 Ubiquitin carboxyl-terminal hydrolase isozyme L5 chr1 Not Cancer Driver No 1 hippie 33 41 7 7 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
UHMK1 UHMK1 Q8TAS1 Serine/threonine-protein kinase Kist chr1 Not Cancer Driver No 1 intact, hippie, biogrid 42 14 2 2 0
UIMC1_ENST00000511320 UIMC1 Q96RL1 BRCA1-A complex subunit RAP80 chr5 Not Cancer Driver No 1 hippie, biogrid 64 609 51 51 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 59 86 6 6 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 2 intact, hippie 188 110 28 28 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VMP1 VMP1 Q96GC9 Vacuole membrane protein 1 chr17 Not Cancer Driver No 1 hippie 57 68 11 11 0
WASHC2A WASHC2A Q641Q2 WASH complex subunit 2A chr10 Not Cancer Driver No 1 hippie 48 1222 42 42 0
WASHC2C_ENST00000374362 WASHC2C Q9Y4E1 WASH complex subunit 2C chr10 Not Cancer Driver No 1 hippie 90 1204 89 89 0
WASHC3 WASHC3 Q9Y3C0 WASH complex subunit 3 chr12 Not Cancer Driver No 1 hippie 29 100 8 8 0
WASHC4_ENST00000332180 WASHC4 Q2M389 WASH complex subunit 4 chr12 Not Cancer Driver No 1 hippie 132 49 1 1 1
WASHC5 WASHC5 Q12768 WASH complex subunit 5 chr8 Not Cancer Driver No 1 intact, hippie 152 23 6 6 6
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 Not Cancer Driver No 1 hippie 30 41 2 2 0
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 79 108 9 9 3
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 1 hippie 22 109 4 4 0
ZBTB18_ENST00000622512 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 78 236 25 25 0