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CAP1_ENST00000372805 ,CAP1 ,Q01518
  • Uniprot Accession= Q01518
  • Ensembl Transcript= ENST00000372805.7
  • Uniprot Name= CAP1
  • Name= Adenylyl cyclase-associated protein 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 16
  • Number of Interaction partner in biogrid: 29
  • Number of Interaction partner in hippie: 92
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 1 hippie 56 361 38 38 0
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 2 hippie, biogrid 70 48 14 14 84
ACTA2 ACTA2 P62736 Actin, aortic smooth muscle chr10 Not Cancer Driver No 2 hippie, biogrid 50 39 4 4 17
ACTBL2 ACTBL2 Q562R1 Beta-actin-like protein 2 chr5 Not Cancer Driver No 3 hippie, biogrid 73 29 5 5 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 4 hippie, biogrid 112 43 5 5 5
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 Not Cancer Driver No 1 hippie 73 42 10 10 16
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 Not Cancer Driver No 1 intact, hippie 65 451 58 58 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 biogrid 29 195 9 9 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 Census Yes 1 hippie 96 384 49 49 0
BCL7A_ENST00000261822 BCL7A Q4VC05 B-cell CLL/lymphoma 7 protein family member A chr12 Census, Compendium Yes 2 hippie, biogrid 24 204 22 22 0
BCL7C_ENST00000215115 BCL7C Q8WUZ0 B-cell CLL/lymphoma 7 protein family member C chr16 Not Cancer Driver No 2 hippie, biogrid 28 209 25 25 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
CAP1_ENST00000372805 CAP1 Q01518 Adenylyl cyclase-associated protein 1 chr1 Not Cancer Driver No 1 hippie 70 156 31 31 0
CAP2 CAP2 P40123 Adenylyl cyclase-associated protein 2 chr6 Not Cancer Driver No 3 hippie, biogrid 81 171 28 28 0
CFL1_ENST00000308162 CFL1 P23528 Cofilin-1 chr11 Not Cancer Driver No 4 hippie, biogrid 21 4 0 0 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 2 intact, hippie 287 145 18 18 151
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 67 17 0 0 10
DNAL4 DNAL4 O96015 Dynein axonemal light chain 4 chr22 Not Cancer Driver No 1 hippie, biogrid 9 15 4 4 0
DPH2 DPH2 Q9BQC3 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 chr1 Not Cancer Driver No 1 hippie, biogrid 77 177 26 26 0
DPYSL2_ENST00000311151 DPYSL2 Q16555 Dihydropyrimidinase-related protein 2 chr8 Not Cancer Driver No 1 hippie, biogrid 86 146 32 32 0
EFNB1 EFNB1 P98172 Ephrin-B1 chrX Not Cancer Driver No 1 hippie 46 126 14 14 19
ENG ENG P17813 Endoglin chr9 Not Cancer Driver No 1 intact, hippie 60 114 15 15 32
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FASN FASN P49327 Fatty acid synthase chr17 Not Cancer Driver No 1 hippie 291 309 42 42 0
FMNL1 FMNL1 O95466 Formin-like protein 1 chr17 Not Cancer Driver No 1 hippie 115 524 32 32 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 intact, hippie 394 1243 185 185 8
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 1 hippie 216 669 76 76 0
GPC1 GPC1 P35052 Glypican-1 chr2 Not Cancer Driver No 1 hippie 58 166 14 14 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie 56 146 13 13 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie 100 254 43 43 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie 94 268 35 35 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 Compendium Yes 1 hippie, biogrid 44 127 9 9 2
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 788 7 2 2 27
LIG4 LIG4 P49917 DNA ligase 4 chr13 Not Cancer Driver No 1 hippie 134 63 10 10 2
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MAP2K2 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 Census Yes 1 intact, hippie, biogrid 58 105 14 14 4
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MCM3_ENST00000229854 MCM3 P25205 DNA replication licensing factor MCM3 chr6 Not Cancer Driver No 1 hippie 92 310 47 47 0
MCM4 MCM4 P33991 DNA replication licensing factor MCM4 chr8 Not Cancer Driver No 1 hippie 121 215 35 35 0
MCM5 MCM5 P33992 DNA replication licensing factor MCM5 chr22 Not Cancer Driver No 2 intact, hippie 88 109 20 20 1
MCM6 MCM6 Q14566 DNA replication licensing factor MCM6 chr2 Not Cancer Driver No 1 hippie 101 122 13 13 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYL12A_ENST00000217652 MYL12A P19105 Myosin regulatory light chain 12A chr18 Not Cancer Driver No 1 hippie, biogrid 19 70 13 13 0
MYLK4 MYLK4 Q86YV6 Myosin light chain kinase family member 4 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 67 77 14 14 0
MYOC MYOC Q99972 Myocilin chr1 Not Cancer Driver No 1 hippie 92 196 43 43 58
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 Not Cancer Driver No 1 hippie 89 88 19 19 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 78 492 49 49 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 35 23 0 0 0
NEK9 NEK9 Q8TD19 Serine/threonine-protein kinase Nek9 chr14 Not Cancer Driver No 1 hippie 88 330 34 34 3
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 230 881 150 150 0
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 Not Cancer Driver No 1 intact, hippie 310 116 43 43 0
NPLOC4 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 78 47 8 8 0
NPRL2 NPRL2 Q8WTW4 GATOR complex protein NPRL2 chr3 Compendium Yes 1 hippie 37 10 3 3 1
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
OGA OGA O60502 Protein O-GlcNAcase chr10 Not Cancer Driver No 1 hippie 89 241 15 15 0
PFN1 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie, biogrid 16 7 1 1 3
PLA2G4A PLA2G4A P47712 Cytosolic phospholipase A2 chr1 Not Cancer Driver No 1 intact, hippie 149 129 28 28 1
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
POTEI POTEI P0CG38 POTE ankyrin domain family member I chr2 Not Cancer Driver No 2 hippie, biogrid 14 449 6 6 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 intact, hippie, biogrid 70 116 11 11 0
PSME2 PSME2 Q9UL46 Proteasome activator complex subunit 2 chr14 Not Cancer Driver No 1 hippie, biogrid 32 39 3 3 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 hippie, biogrid 62 341 24 24 0
RNASEH2C RNASEH2C Q8TDP1 Ribonuclease H2 subunit C chr11 Not Cancer Driver No 1 hippie, biogrid 6 80 2 2 7
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 Not Cancer Driver No 1 hippie 176 241 21 21 0
SERPINB8 SERPINB8 P50452 Serpin B8 chr18 Not Cancer Driver No 1 hippie 74 4 0 0 0
SHTN1 SHTN1 A0MZ66 Shootin-1 chr10 Census Yes 1 hippie 68 470 52 52 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 Not Cancer Driver No 1 hippie 70 435 31 31 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
STK25 STK25 O00506 Serine/threonine-protein kinase 25 chr2 Not Cancer Driver No 1 hippie 42 170 15 15 0
TPM3 TPM3 P06753 Tropomyosin alpha-3 chain chr1 Census Yes 1 hippie 35 230 27 27 21
TPM4_ENST00000300933 TPM4 P67936 Tropomyosin alpha-4 chain chr19 Census Yes 1 hippie 28 216 28 28 0
TTC38 TTC38 Q5R3I4 Tetratricopeptide repeat protein 38 chr22 Not Cancer Driver No 1 hippie, biogrid 65 37 3 3 0
TULP3_ENST00000448120 TULP3 O75386 Tubby-related protein 3 chr12 Not Cancer Driver No 1 hippie 66 218 29 29 0
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 50 52 3 3 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 Not Cancer Driver No 2 hippie, biogrid 34 59 8 8 0
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 1 hippie 78 191 28 28 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UCHL5 UCHL5 Q9Y5K5 Ubiquitin carboxyl-terminal hydrolase isozyme L5 chr1 Not Cancer Driver No 1 hippie 33 41 7 7 0
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 Not Cancer Driver No 1 hippie 26 100 7 7 0
VDAC2_ENST00000543351 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 35 9 1 1 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WLS_ENST00000262348 WLS Q5T9L3 Protein wntless homolog chr1 Not Cancer Driver No 1 intact, hippie 71 14 3 3 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0