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BCL10 ,BCL10 ,O95999
  • Uniprot Accession= O95999
  • Ensembl Transcript= ENST00000370580.5
  • Uniprot Name= BCL10
  • Name= B-cell lymphoma/leukemia 10
  • Chromosome= chr1
  • Driver status= Census, Compendium
  • Number of Interaction partner in intact: 30
  • Number of Interaction partner in biogrid: 9
  • Number of Interaction partner in hippie: 86
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 2 intact, hippie 108 158 24 24 4
ANP32B ANP32B Q92688 Acidic leucine-rich nuclear phosphoprotein 32 family member B chr9 Not Cancer Driver No 1 hippie 22 117 12 12 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 40 25 6 6 1
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 Census, Compendium Yes 1 hippie 469 225 39 39 41
BAAT_ENST00000395051 BAAT Q14032 Bile acid-CoA:amino acid N-acyltransferase chr9 Not Cancer Driver No 1 intact, hippie 88 10 4 4 1
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 Census, Compendium Yes 4 intact, hippie 36 151 25 25 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 Census Yes 1 intact, hippie 44 259 23 23 0
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 Not Cancer Driver No 2 hippie, biogrid 69 83 9 9 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 2 hippie, biogrid 77 98 16 16 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 intact, hippie 80 45 4 4 0
CAMK2G_ENST00000423381 CAMK2G Q13555 Calcium/calmodulin-dependent protein kinase type II subunit gamma chr10 Not Cancer Driver No 1 hippie 68 145 14 14 1
CARD10_ENST00000251973 CARD10 Q9BWT7 Caspase recruitment domain-containing protein 10 chr22 Not Cancer Driver No 1 hippie 94 474 40 40 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 Census, Compendium Yes 9 intact, hippie 303 530 140 140 5
CARD14 CARD14 Q9BXL6 Caspase recruitment domain-containing protein 14 chr17 Not Cancer Driver No 1 hippie 99 296 36 36 11
CARD19 CARD19 Q96LW7-2 Isoform 2 of Caspase recruitment domain-containing protein 19 chr9 Not Cancer Driver No 1 hippie 18 30 2 2 0
CARD9 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 Not Cancer Driver No 3 intact, hippie 72 225 35 35 11
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 Census, Compendium Yes 1 intact, hippie 142 106 12 12 1
CASP9 CASP9 P55211 Caspase-9 chr1 Census Yes 1 hippie 49 71 7 7 0
CCDC180 CCDC180 Q9P1Z9 Coiled-coil domain-containing protein 180 chr9 Not Cancer Driver No 1 intact, hippie 212 588 96 96 0
CDC14B CDC14B O60729 Dual specificity protein phosphatase CDC14B chr9 Not Cancer Driver No 1 intact, hippie 61 138 15 15 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 intact, hippie 50 34 2 2 0
CHUK CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 Not Cancer Driver No 1 hippie 74 116 9 9 0
COG6 COG6 Q9Y2V7 Conserved oligomeric Golgi complex subunit 6 chr13 Not Cancer Driver No 2 intact, hippie 83 141 16 16 1
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 2 intact, hippie 44 46 3 3 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 Not Cancer Driver No 1 hippie 151 8 1 1 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ENG ENG P17813 Endoglin chr9 Not Cancer Driver No 1 intact, hippie 60 114 15 15 32
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 Not Cancer Driver No 1 hippie 33 19 0 0 4
FGFR1OP CEP43 O95684 Centrosomal protein 43 chr6 Not Cancer Driver No 1 intact 43 272 33 33 0
FYB1_ENST00000515010 FYB1 O15117 FYN-binding protein 1 chr5 Not Cancer Driver No 1 hippie 176 687 161 161 0
HEMGN_ENST00000259456 HEMGN Q9BXL5 Hemogen chr9 Not Cancer Driver No 1 intact, hippie 78 473 73 73 0
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 Census, Compendium Yes 1 intact, hippie 106 211 31 31 1
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 2 intact, hippie 6 301 6 6 22
IL15RA_ENST00000379977 IL15RA Q13261 Interleukin-15 receptor subunit alpha chr10 Not Cancer Driver No 1 intact, hippie 40 173 32 32 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX Compendium Yes 1 hippie 71 337 39 39 0
KRT33B KRT33B Q14525 Keratin, type I cuticular Ha3-II chr17 Not Cancer Driver No 1 hippie, biogrid 87 59 18 18 0
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 Census, Compendium Yes 2 hippie, biogrid 75 139 12 12 1
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 22 24 1 1 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 Compendium Yes 1 hippie 89 144 20 20 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 hippie 104 333 66 66 6
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 Not Cancer Driver No 1 hippie 59 90 8 8 0
MIB2_ENST00000504599 MIB2 Q96AX9 E3 ubiquitin-protein ligase MIB2 chr1 Not Cancer Driver No 1 hippie 88 307 31 31 0
NANS NANS Q9NR45 Sialic acid synthase chr9 Not Cancer Driver No 1 hippie 29 45 1 1 6
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 Compendium Yes 1 hippie 37 102 9 9 1
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 Not Cancer Driver No 1 hippie 205 15 2 2 3
OTULIN OTULIN Q96BN8 Ubiquitin thioesterase otulin chr5 Not Cancer Driver No 1 hippie 47 97 5 5 2
PELI2 PELI2 Q9HAT8 E3 ubiquitin-protein ligase pellino homolog 2 chr14 Not Cancer Driver No 1 hippie 80 162 38 38 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 1 hippie 41 12 1 1 8
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 1 hippie 179 0 0 0 4
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 Not Cancer Driver No 1 intact, hippie 147 28 9 9 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 intact, hippie 70 116 11 11 0
PRPS2_ENST00000380668 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX Not Cancer Driver No 1 hippie, biogrid 56 4 1 1 0
PRRG4 PRRG4 Q9BZD6 Transmembrane gamma-carboxyglutamic acid protein 4 chr11 Not Cancer Driver No 1 intact, hippie 17 53 8 8 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 Not Cancer Driver No 1 hippie 16 39 4 4 0
QKI QKI Q96PU8 Protein quaking chr6 Census, Compendium Yes 1 intact, hippie 52 174 27 27 0
RAB20 RAB20 Q9NX57 Ras-related protein Rab-20 chr13 Not Cancer Driver No 1 hippie, biogrid 33 57 8 8 0
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 Compendium Yes 1 hippie 154 181 25 25 3
RBCK1 RBCK1 Q9BYM8 RanBP-type and C3HC4-type zinc finger-containing protein 1 chr20 Not Cancer Driver No 1 hippie 52 140 14 14 2
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 Not Cancer Driver No 1 hippie 63 143 20 20 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 Not Cancer Driver No 1 hippie 77 471 66 66 0
RNF181 RNF181 Q9P0P0 E3 ubiquitin-protein ligase RNF181 chr2 Not Cancer Driver No 1 hippie 15 63 8 8 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 Not Cancer Driver No 1 hippie 142 319 45 45 0
RNF8 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 Not Cancer Driver No 1 hippie 56 226 29 29 0
SHARPIN SHARPIN Q9H0F6 Sharpin chr8 Not Cancer Driver No 1 intact, hippie 34 237 16 16 0
SLC20A1 SLC20A1 Q8WUM9 Sodium-dependent phosphate transporter 1 chr2 Not Cancer Driver No 1 intact, hippie 67 157 9 9 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 Not Cancer Driver No 1 intact, hippie 19 318 16 16 4
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 Not Cancer Driver No 1 hippie 27 111 14 14 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
SRSF1 SRSF1 Q07955 Serine/arginine-rich splicing factor 1 chr17 Not Cancer Driver No 1 hippie 41 198 34 34 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 Not Cancer Driver No 1 intact, hippie 41 41 4 4 10
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 Not Cancer Driver No 1 hippie 292 0 0 0 0
TMEM43 TMEM43 Q9BTV4 Transmembrane protein 43 chr3 Not Cancer Driver No 1 hippie 47 57 9 9 3
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 Not Cancer Driver No 1 hippie 55 174 17 17 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 1 hippie 58 111 15 15 12
TRADD TRADD Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein chr16 Not Cancer Driver No 1 hippie 26 74 5 5 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 5 intact, hippie, biogrid 63 4 1 1 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 67 62 7 7 0
TRMO TRMO Q9BU70 tRNA (adenine(37)-N6)-methyltransferase chr9 Not Cancer Driver No 1 intact, hippie 57 228 25 25 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 Not Cancer Driver No 1 hippie 25 24 3 3 0
UBE2V2 UBE2V2 Q15819 Ubiquitin-conjugating enzyme E2 variant 2 chr8 Not Cancer Driver No 1 hippie 22 76 12 12 0
USHBP1 USHBP1 Q8N6Y0 Usher syndrome type-1C protein-binding protein 1 chr19 Not Cancer Driver No 1 intact, hippie 118 583 95 95 0
USP9X_ENST00000378308 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX Census, Compendium Yes 1 hippie 339 405 51 51 1
VAPB VAPB O95292 Vesicle-associated membrane protein-associated protein B/C chr20 Not Cancer Driver No 1 hippie, biogrid 16 138 8 8 3
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX Not Cancer Driver No 1 hippie 89 55 6 6 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
ZNF444 ZNF444 Q8N0Y2 Zinc finger protein 444 chr19 Not Cancer Driver No 1 hippie, biogrid 17 221 13 13 0