Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACAA2 | ACAA2 | P42765 | 3-ketoacyl-CoA thiolase, mitochondrial | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 51 | 2 | 2 | 0 |
| ACAT1 | ACAT1 | P24752 | Acetyl-CoA acetyltransferase, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 32 | 1 | 1 | 10 |
| ACO2 | ACO2 | Q99798 | Aconitate hydratase, mitochondrial | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 94 | 172 | 19 | 19 | 5 |
| ADGRL3 | ADGRL3 | Q9HAR2 | Adhesion G protein-coupled receptor L3 | chr4 | Not Cancer Driver | No | 1 | hippie | 440 | 517 | 130 | 130 | 0 |
| AGR2 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 20 | 2 | 2 | 0 |
| AGTR1_ENST00000349243 | AGTR1 | P30556 | Type-1 angiotensin II receptor | chr3 | Not Cancer Driver | No | 1 | hippie | 95 | 0 | 0 | 0 | 1 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 128 | 418 | 71 | 71 | 17 |
| ATP12A_ENST00000381946 | ATP12A | P54707 | Potassium-transporting ATPase alpha chain 2 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 203 | 117 | 24 | 24 | 0 |
| ATP1A1_ENST00000295598 | ATP1A1 | P05023 | Sodium/potassium-transporting ATPase subunit alpha-1 | chr1 | Census | Yes | 6 | intact, hippie, biogrid | 115 | 115 | 16 | 16 | 6 |
| ATP1A3_ENST00000302102 | ATP1A3 | P13637 | Sodium/potassium-transporting ATPase subunit alpha-3 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 200 | 115 | 29 | 29 | 31 |
| ATP2A2 | ATP2A2 | P16615 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 136 | 78 | 14 | 14 | 41 |
| ATP4A | ATP4A | P20648 | Potassium-transporting ATPase alpha chain 1 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 201 | 121 | 30 | 30 | 0 |
| ATP5MG | ATP5MG | O75964 | ATP synthase subunit g, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie | 16 | 0 | 0 | 0 | 0 |
| ATP5PB | ATP5PB | P24539 | ATP synthase F(0) complex subunit B1, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 37 | 2 | 0 | 0 | 0 |
| ATP6V1E1 | ATP6V1E1 | P36543 | V-type proton ATPase subunit E 1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 27 | 3 | 3 | 2 |
| BACE1 | BACE1 | P56817 | Beta-secretase 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 55 | 53 | 5 | 5 | 0 |
| BARD1 | BARD1 | Q99728 | BRCA1-associated RING domain protein 1 | chr2 | Census | Yes | 1 | hippie | 96 | 384 | 49 | 49 | 0 |
| BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 224 | 1458 | 174 | 174 | 35 |
| CA9 | CA9 | Q16790 | Carbonic anhydrase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 72 | 274 | 50 | 50 | 0 |
| CANX_ENST00000504734 | CANX | P27824 | Calnexin | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 334 | 38 | 38 | 0 |
| CCDC8 | CCDC8 | Q9H0W5 | Coiled-coil domain-containing protein 8 | chr19 | Not Cancer Driver | No | 1 | hippie | 96 | 505 | 91 | 91 | 0 |
| CD81 | CD81 | P60033 | CD81 antigen | chr11 | Not Cancer Driver | No | 1 | hippie | 28 | 0 | 0 | 0 | 0 |
| CD9 | CD9 | P21926 | CD9 antigen | chr12 | Not Cancer Driver | No | 1 | hippie | 22 | 0 | 0 | 0 | 0 |
| CISD2 | CISD2 | Q8N5K1 | CDGSH iron-sulfur domain-containing protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 7 | 0 | 0 | 0 |
| CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
| CLSTN1 | CLSTN1 | O94985 | Calsyntenin-1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 110 | 271 | 22 | 22 | 0 |
| COX6B1_ENST00000592141 | COX6B1 | P14854 | Cytochrome c oxidase subunit 6B1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 23 | 6 | 6 | 2 |
| CPT2 | CPT2 | P23786 | Carnitine O-palmitoyltransferase 2, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 70 | 5 | 5 | 21 |
| CRIP2_ENST00000329146 | CRIP2 | P52943 | Cysteine-rich protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie | 15 | 68 | 3 | 3 | 0 |
| CTSD | CTSD | P07339 | Cathepsin D | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 6 | 1 | 1 | 2 |
| CYC1 | CYC1 | P08574 | Cytochrome c1, heme protein, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 35 | 8 | 8 | 2 |
| DDAH2_ENST00000375787 | DDAH2 | O95865 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 24 | 96 | 6 | 6 | 0 |
| DLAT | DLAT | P10515 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 294 | 42 | 42 | 0 |
| DLD | DLD | P09622 | Dihydrolipoyl dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 17 | 0 | 0 | 10 |
| DNAJC11 | DNAJC11 | Q9NVH1 | DnaJ homolog subfamily C member 11 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 123 | 14 | 14 | 0 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
| EIF4H | EIF4H | Q15056 | Eukaryotic translation initiation factor 4H | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 175 | 17 | 17 | 0 |
| ELAVL1 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 69 | 43 | 5 | 5 | 0 |
| ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
| EZH2_ENST00000460911 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | Census, Compendium | Yes | 1 | hippie | 120 | 284 | 44 | 44 | 11 |
| FLNB_ENST00000295956 | FLNB | O75369 | Filamin-B | chr3 | Not Cancer Driver | No | 1 | hippie | 362 | 1183 | 170 | 170 | 19 |
| FUBP1 | FUBP1 | Q96AE4 | Far upstream element-binding protein 1 | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 88 | 595 | 85 | 85 | 0 |
| FXYD1_ENST00000455515 | FXYD1 | O00168 | Phospholemman | chr19 | Not Cancer Driver | No | 1 | hippie | 10 | 22 | 4 | 4 | 0 |
| FXYD7 | FXYD7 | P58549 | FXYD domain-containing ion transport regulator 7 | chr19 | Not Cancer Driver | No | 1 | hippie | 7 | 43 | 2 | 2 | 0 |
| GCH1_ENST00000622544 | GCH1 | P30793 | GTP cyclohydrolase 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 20 | 99 | 5 | 5 | 38 |
| GLRX_ENST00000505427 | GLRX | P35754 | Glutaredoxin-1 | chr5 | Not Cancer Driver | No | 1 | intact | 14 | 0 | 0 | 0 | 0 |
| HADHA | HADHA | P40939 | Trifunctional enzyme subunit alpha, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 19 | 2 | 2 | 5 |
| HADHB | HADHB | P55084 | Trifunctional enzyme subunit beta, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 41 | 9 | 9 | 14 |
| HAVCR1_ENST00000339252 | HAVCR1 | Q96D42 | Hepatitis A virus cellular receptor 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 95 | 156 | 48 | 48 | 0 |
| HLA-C | HLA-C | P10321 | HLA class I histocompatibility antigen, C alpha chain | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 104 | 175 | 58 | 58 | 0 |
| HLA-DRA | HLA-DRA | P01903 | HLA class II histocompatibility antigen, DR alpha chain | chr6 | Not Cancer Driver | No | 1 | hippie | 52 | 12 | 1 | 1 | 0 |
| HLA-DRB1 | HLA-DRB1 | P01911 | HLA class II histocompatibility antigen, DRB1 beta chain | chr6 | Not Cancer Driver | No | 1 | hippie | 48 | 12 | 1 | 1 | 0 |
| HLA-DRB5 | HLA-DRB5 | Q30154 | HLA class II histocompatibility antigen, DR beta 5 chain | chr6 | Not Cancer Driver | No | 1 | hippie | 35 | 18 | 2 | 2 | 0 |
| HNRNPA2B1 | HNRNPA2B1 | P22626 | Heterogeneous nuclear ribonucleoproteins A2/B1 | chr7 | Census, Compendium | Yes | 1 | hippie, biogrid | 68 | 255 | 41 | 41 | 0 |
| HNRNPA3 | HNRNPA3 | P51991 | Heterogeneous nuclear ribonucleoprotein A3 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 285 | 37 | 37 | 0 |
| HNRNPH1 | HNRNPH1 | P31943 | Heterogeneous nuclear ribonucleoprotein H | chr5 | Not Cancer Driver | No | 1 | hippie | 51 | 169 | 29 | 29 | 0 |
| HSD17B10 | HSD17B10 | Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 15 | 3 | 3 | 11 |
| HSD17B12 | HSD17B12 | Q53GQ0 | Very-long-chain 3-oxoacyl-CoA reductase | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 9 | 0 | 0 | 0 |
| HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 282 | 35 | 35 | 0 |
| HSPA9 | HSPA9 | P38646 | Stress-70 protein, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie | 67 | 283 | 26 | 26 | 2 |
| HSPB2 | HSPB2 | Q16082 | Heat shock protein beta-2 | chr11 | Not Cancer Driver | No | 1 | intact | 25 | 103 | 11 | 11 | 0 |
| HTR2B | HTR2B | P41595 | 5-hydroxytryptamine receptor 2B | chr2 | Not Cancer Driver | No | 1 | hippie | 41 | 23 | 2 | 2 | 0 |
| HTT | HTT | P42858 | Huntingtin | chr4 | Not Cancer Driver | No | 1 | hippie | 336 | 666 | 69 | 69 | 2 |
| IGSF3_ENST00000369486 | IGSF3 | O75054 | Immunoglobulin superfamily member 3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 184 | 224 | 34 | 34 | 0 |
| ILVBL | ILVBL | A1L0T0 | 2-hydroxyacyl-CoA lyase 2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 30 | 1 | 1 | 0 |
| KCNMA1 | KCNMA1 | Q12791 | Calcium-activated potassium channel subunit alpha-1 | chr10 | Not Cancer Driver | No | 1 | intact | 222 | 225 | 39 | 39 | 5 |
| KIAA0319L | KIAA0319L | Q8IZA0 | Dyslexia-associated protein KIAA0319-like protein | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 117 | 508 | 58 | 58 | 0 |
| KIRREL3 | KIRREL3 | Q8IZU9 | Kin of IRRE-like protein 3 | chr11 | Not Cancer Driver | No | 1 | hippie | 111 | 223 | 32 | 32 | 0 |
| KMT2B | KMT2B | Q9UMN6 | Histone-lysine N-methyltransferase 2B | chr19 | Compendium | Yes | 1 | hippie | 378 | 1895 | 227 | 227 | 0 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | Not Cancer Driver | No | 1 | hippie | 54 | 65 | 16 | 16 | 0 |
| LMAN1 | LMAN1 | P49257 | Protein ERGIC-53 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 222 | 25 | 25 | 1 |
| LRIF1 | LRIF1 | Q5T3J3 | Ligand-dependent nuclear receptor-interacting factor 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 116 | 520 | 74 | 74 | 0 |
| MLC1 | MLC1 | Q15049 | Membrane protein MLC1 | chr22 | Not Cancer Driver | No | 1 | hippie | 53 | 35 | 7 | 7 | 15 |
| MRPS35 | MRPS35 | P82673 | 28S ribosomal protein S35, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 92 | 13 | 13 | 0 |
| MTCH1 | MTCH1 | Q9NZJ7 | Mitochondrial carrier homolog 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 102 | 2 | 2 | 0 |
| MTCH2 | MTCH2 | Q9Y6C9 | Mitochondrial carrier homolog 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 11 | 0 | 0 | 0 |
| NDRG1 | NDRG1 | Q92597 | Protein NDRG1 | chr8 | Census | Yes | 1 | hippie, biogrid | 66 | 140 | 22 | 22 | 0 |
| NDRG2 | NDRG2 | Q9UN36 | Protein NDRG2 | chr14 | Not Cancer Driver | No | 1 | hippie | 45 | 111 | 8 | 8 | 0 |
| NDRG3 | NDRG3 | Q9UGV2 | Protein NDRG3 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 109 | 16 | 16 | 0 |
| NDUFA12 | NDUFA12 | Q9UI09 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 31 | 6 | 6 | 0 |
| NDUFA2 | NDUFA2 | O43678 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 0 | 0 | 0 | 0 |
| NDUFS1_ENST00000449699 | NDUFS1 | P28331 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 40 | 3 | 3 | 2 |
| NDUFS3 | NDUFS3 | O75489 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 26 | 3 | 3 | 2 |
| NDUFV1 | NDUFV1 | P49821 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 57 | 9 | 9 | 3 |
| NEDD4L | NEDD4L | Q96PU5 | E3 ubiquitin-protein ligase NEDD4-like | chr18 | Not Cancer Driver | No | 1 | hippie | 126 | 463 | 60 | 60 | 4 |
| NIPSNAP2 | NIPSNAP2 | O75323 | Protein NipSnap homolog 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 30 | 6 | 1 | 1 | 0 |
| NPC1 | NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 155 | 24 | 0 | 0 | 150 |
| NR3C1_ENST00000343796 | NR3C1 | P04150 | Glucocorticoid receptor | chr5 | Not Cancer Driver | No | 1 | hippie | 92 | 362 | 37 | 37 | 12 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
| OGT | OGT | O15294 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | chrX | Not Cancer Driver | No | 1 | hippie | 156 | 89 | 16 | 16 | 2 |
| OMA1 | OMA1 | Q96E52 | Metalloendopeptidase OMA1, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 34 | 4 | 4 | 0 |
| P2RY6_ENST00000540342 | P2RY6 | Q15077 | P2Y purinoceptor 6 | chr11 | Not Cancer Driver | No | 1 | hippie | 50 | 10 | 5 | 5 | 0 |
| PANX1 | PANX1 | Q96RD7 | Pannexin-1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 45 | 7 | 7 | 2 |
| PAXIP1 | PAXIP1 | Q6ZW49 | PAX-interacting protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 120 | 461 | 39 | 39 | 0 |
| PDCD5 | PDCD5 | O14737 | Programmed cell death protein 5 | chr19 | Not Cancer Driver | No | 1 | hippie | 15 | 91 | 7 | 7 | 0 |
| PDHA1_ENST00000422285 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 43 | 6 | 6 | 20 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PMAIP1 | PMAIP1 | Q13794 | Phorbol-12-myristate-13-acetate-induced protein 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 2 | 23 | 1 | 1 | 0 |
| PRNP | PRNP | P04156 | Major prion protein | chr20 | Not Cancer Driver | No | 1 | hippie | 36 | 115 | 7 | 7 | 18 |
| PSMD6_ENST00000295901 | PSMD6 | Q15008 | 26S proteasome non-ATPase regulatory subunit 6 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 40 | 3 | 3 | 0 |
| PSME1_ENST00000206451 | PSME1 | Q06323 | Proteasome activator complex subunit 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 20 | 80 | 8 | 8 | 0 |
| RAB1A | RAB1A | P62820 | Ras-related protein Rab-1A | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 38 | 2 | 2 | 0 |
| RAB1B | RAB1B | Q9H0U4 | Ras-related protein Rab-1B | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 40 | 3 | 3 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
| RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 2 |
| RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 1 | hippie | 52 | 19 | 2 | 2 | 0 |
| RHOC_ENST00000369642 | RHOC | P08134 | Rho-related GTP-binding protein RhoC | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 53 | 7 | 7 | 0 |
| RHOF | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 10 | 0 | 0 | 0 |
| RHOJ | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
| RIF1 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | Not Cancer Driver | No | 1 | hippie | 287 | 1355 | 164 | 164 | 0 |
| RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
| RPL26 | RPL26 | P61254 | 60S ribosomal protein L26 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 114 | 13 | 13 | 0 |
| RPS19_ENST00000600467 | RPS19 | P39019 | 40S ribosomal protein S19 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 61 | 3 | 3 | 23 |
| RTN4 | RTN4 | Q9NQC3 | Reticulon-4 | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 121 | 866 | 82 | 82 | 0 |
| S100A9 | S100A9 | P06702 | Protein S100-A9 | chr1 | Not Cancer Driver | No | 1 | hippie | 18 | 76 | 7 | 7 | 0 |
| SC5D_ENST00000392789 | SC5D | O75845 | Lathosterol oxidase | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 21 | 3 | 3 | 3 |
| SDHA | SDHA | P31040 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | chr5 | Census | Yes | 1 | hippie, biogrid | 115 | 71 | 13 | 13 | 7 |
| SGCB | SGCB | Q16585 | Beta-sarcoglycan | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 80 | 8 | 8 | 12 |
| SLC15A3 | SLC15A3 | Q8IY34 | Solute carrier family 15 member 3 | chr11 | Not Cancer Driver | No | 1 | hippie | 63 | 43 | 1 | 1 | 0 |
| SLC4A1 | SLC4A1 | P02730 | Band 3 anion transport protein | chr17 | Not Cancer Driver | No | 1 | hippie | 153 | 130 | 23 | 23 | 39 |
| SLITRK5 | SLITRK5 | O94991 | SLIT and NTRK-like protein 5 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 257 | 346 | 93 | 93 | 0 |
| SMAD2_ENST00000402690 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | Census, Compendium | Yes | 1 | hippie | 79 | 137 | 12 | 12 | 0 |
| SNAP25 | SNAP25 | P60880 | Synaptosomal-associated protein 25 | chr20 | Not Cancer Driver | No | 1 | hippie | 61 | 176 | 49 | 49 | 1 |
| SPPL2B | SPPL2B | Q8TCT7 | Signal peptide peptidase-like 2B | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 99 | 17 | 17 | 0 |
| SST | SST | P61278 | Somatostatin | chr3 | Not Cancer Driver | No | 1 | hippie | 25 | 40 | 15 | 15 | 0 |
| STX4 | STX4 | Q12846 | Syntaxin-4 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 152 | 20 | 20 | 0 |
| TARDBP | TARDBP | Q13148 | TAR DNA-binding protein 43 | chr1 | Not Cancer Driver | No | 1 | hippie | 51 | 202 | 15 | 15 | 27 |
| TEX101_ENST00000598265 | TEX101 | Q9BY14 | Testis-expressed protein 101 | chr19 | Not Cancer Driver | No | 1 | hippie | 45 | 2 | 0 | 0 | 0 |
| TM9SF1 | TM9SF1 | O15321 | Transmembrane 9 superfamily member 1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 15 | 4 | 4 | 0 |
| TM9SF2 | TM9SF2 | Q99805 | Transmembrane 9 superfamily member 2 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 16 | 2 | 2 | 0 |
| TM9SF3 | TM9SF3 | Q9HD45 | Transmembrane 9 superfamily member 3 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 2 | 0 | 0 | 0 |
| TMEM259 | TMEM259 | Q4ZIN3 | Membralin | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 188 | 9 | 9 | 0 |
| TMEM67 | TMEM67 | Q5HYA8 | Meckelin | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 120 | 11 | 0 | 0 | 37 |
| TMPRSS11B | TMPRSS11B | Q86T26 | Transmembrane protease serine 11B | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 5 | 0 | 0 | 0 |
| TOMM40_ENST00000405636 | TOMM40 | O96008 | Mitochondrial import receptor subunit TOM40 homolog | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 98 | 1 | 1 | 0 |
| TRAF3_ENST00000392745 | TRAF3 | Q13114 | TNF receptor-associated factor 3 | chr14 | Compendium | Yes | 1 | hippie | 61 | 101 | 9 | 9 | 1 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | Not Cancer Driver | No | 1 | hippie | 67 | 62 | 7 | 7 | 0 |
| TRIM14 | TRIM14 | Q14142 | Tripartite motif-containing protein 14 | chr9 | Not Cancer Driver | No | 1 | hippie | 36 | 93 | 7 | 7 | 0 |
| TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
| TRMT2A_ENST00000403707 | TRMT2A | Q8IZ69 | tRNA (uracil-5-)-methyltransferase homolog A | chr22 | Not Cancer Driver | No | 1 | hippie | 64 | 157 | 20 | 20 | 0 |
| TSC22D2 | TSC22D2 | O75157 | TSC22 domain family protein 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 64 | 723 | 59 | 59 | 0 |
| TSPAN6 | TSPAN6 | O43657 | Tetraspanin-6 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 0 | 0 | 0 | 0 |
| TUBB1 | TUBB1 | Q9H4B7 | Tubulin beta-1 chain | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 38 | 4 | 4 | 1 |
| TUBB8 | TUBB8 | Q3ZCM7 | Tubulin beta-8 chain | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 103 | 53 | 18 | 18 | 13 |
| TXNDC15 | TXNDC15 | Q96J42 | Thioredoxin domain-containing protein 15 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 137 | 15 | 15 | 0 |
| UNC93B1 | UNC93B1 | Q9H1C4 | Protein unc-93 homolog B1 | chr11 | Not Cancer Driver | No | 1 | hippie | 57 | 127 | 5 | 5 | 0 |
| UQCRB_ENST00000287022 | UQCRB | P14927 | Cytochrome b-c1 complex subunit 7 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 2 | 1 | 1 | 0 |
| UQCRFS1 | UQCRFS1 | P47985 | Cytochrome b-c1 complex subunit Rieske, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 47 | 4 | 4 | 1 |
| UQCRQ_ENST00000378665 | UQCRQ | O14949 | Cytochrome b-c1 complex subunit 8 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 9 | 12 | 1 | 1 | 1 |
| USP4 | USP4 | Q13107 | Ubiquitin carboxyl-terminal hydrolase 4 | chr3 | Not Cancer Driver | No | 1 | hippie | 102 | 286 | 22 | 22 | 0 |
| VDAC1_ENST00000395047 | VDAC1 | P21796 | Voltage-dependent anion-selective channel protein 1 | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 38 | 36 | 4 | 4 | 0 |
| VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
| WFS1_ENST00000503569 | WFS1 | O76024 | Wolframin | chr4 | Not Cancer Driver | No | 1 | hippie | 105 | 203 | 10 | 10 | 39 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|