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ATF6 ,ATF6 ,P18850
  • Uniprot Accession= P18850
  • Ensembl Transcript= ENST00000367942.3
  • Uniprot Name= ATF6
  • Name= Cyclic AMP-dependent transcription factor ATF-6 alpha
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 63
  • Number of Interaction partner in hippie: 110
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 42 51 2 2 0
ACLY_ENST00000590151 ACLY P53396 ATP-citrate synthase chr17 Not Cancer Driver No 1 hippie 120 114 12 12 0
APOD APOD P05090 Apolipoprotein D chr3 Not Cancer Driver No 1 hippie 34 13 2 2 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 Not Cancer Driver No 1 hippie 88 468 59 59 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 Not Cancer Driver No 1 hippie 70 557 59 59 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 65 456 42 42 5
BPGM_ENST00000344924 BPGM P07738 Bisphosphoglycerate mutase chr7 Not Cancer Driver No 1 hippie 34 15 0 0 2
BTNL2_ENST00000374993 BTNL2 Q9UIR0 Butyrophilin-like protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 66 82 16 16 0
BTNL3 BTNL3 Q6UXE8 Butyrophilin-like protein 3 chr5 Not Cancer Driver No 1 hippie, biogrid 79 50 13 13 0
CCDC107 CCDC107 Q8WV48 Coiled-coil domain-containing protein 107 chr9 Not Cancer Driver No 1 hippie, biogrid 14 215 12 12 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 Not Cancer Driver No 1 hippie, biogrid 20 2 0 0 0
CD300E CD300E Q496F6 CMRF35-like molecule 2 chr17 Not Cancer Driver No 1 hippie, biogrid 55 38 11 11 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDH5 CDH5 P33151 Cadherin-5 chr16 Not Cancer Driver No 2 hippie, biogrid 144 305 55 55 0
CEBPD CEBPD P49716 CCAAT/enhancer-binding protein delta chr8 Not Cancer Driver No 1 hippie 5 234 4 4 0
CHRNB1 CHRNB1 P11230 Acetylcholine receptor subunit beta chr17 Not Cancer Driver No 1 hippie, biogrid 62 45 9 9 3
CLEC2D_ENST00000290855 CLEC2D Q9UHP7 C-type lectin domain family 2 member D chr12 Not Cancer Driver No 1 hippie, biogrid 28 14 1 1 0
CLEC3A CLEC3A O75596 C-type lectin domain family 3 member A chr16 Not Cancer Driver No 2 hippie, biogrid 65 21 3 3 0
COP1 COP1 Q8NHY2 E3 ubiquitin-protein ligase COP1 chr1 Not Cancer Driver No 1 hippie 106 147 11 11 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 Census Yes 1 hippie 25 277 23 23 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 Not Cancer Driver No 1 hippie 96 338 67 67 1
CRTC2 CRTC2 Q53ET0 CREB-regulated transcription coactivator 2 chr1 Not Cancer Driver No 1 hippie 92 674 88 88 0
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 Not Cancer Driver No 1 hippie, biogrid 113 10 3 3 2
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 Not Cancer Driver No 1 hippie 193 114 11 11 0
DDC DDC P20711 Aromatic-L-amino-acid decarboxylase chr7 Not Cancer Driver No 1 hippie 98 5 0 0 9
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 28 11 1 1 0
DET1_ENST00000268148 DET1 Q7L5Y6 DET1 homolog chr15 Not Cancer Driver No 1 hippie, biogrid 97 42 12 12 0
DNAJC1 DNAJC1 Q96KC8 DnaJ homolog subfamily C member 1 chr10 Not Cancer Driver No 1 hippie, biogrid 60 315 44 44 0
DNAJC16 DNAJC16 Q9Y2G8 DnaJ homolog subfamily C member 16 chr1 Not Cancer Driver No 1 hippie, biogrid 84 63 2 2 0
DNAJC25 DNAJC25 Q9H1X3 DnaJ homolog subfamily C member 25 chr9 Not Cancer Driver No 1 hippie, biogrid 37 39 3 3 0
EDDM3B EDDM3B P56851 Epididymal secretory protein E3-beta chr14 Not Cancer Driver No 1 hippie, biogrid 24 0 0 0 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 Not Cancer Driver No 1 hippie 149 410 51 51 1
ELOVL5_ENST00000304434 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 Not Cancer Driver No 1 hippie, biogrid 34 25 4 4 2
EMD EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie, biogrid 42 160 28 28 4
EPHX2 EPHX2 P34913 Bifunctional epoxide hydrolase 2 chr8 Not Cancer Driver No 1 hippie, biogrid 78 26 3 3 0
ERLEC1 ERLEC1 Q96DZ1 Endoplasmic reticulum lectin 1 chr2 Not Cancer Driver No 3 hippie, biogrid 54 134 17 17 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 Not Cancer Driver No 1 hippie 125 250 28 28 0
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 21 75 1 1 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FHL3 FHL3 Q13643 Four and a half LIM domains protein 3 chr1 Not Cancer Driver No 1 hippie, biogrid 33 0 0 0 0
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 hippie, biogrid 71 160 25 25 0
GABRD GABRD O14764 Gamma-aminobutyric acid receptor subunit delta chr1 Not Cancer Driver No 2 hippie, biogrid 71 19 5 5 1
GPIHBP1 GPIHBP1 Q8IV16 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 26 82 15 15 10
GTF2I GTF2I P78347 General transcription factor II-I chr7 Compendium Yes 1 hippie 74 365 27 27 0
HIBADH HIBADH P31937 3-hydroxyisobutyrate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 28 7 2 2 0
HLA-DQA1 HLA-DQA1 A0A173ADG5 HLA class II histocompatibility antigen DQ alpha chain chr6 Not Cancer Driver No 1 hippie, biogrid 29 5 0 0 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 Not Cancer Driver No 2 hippie, biogrid 63 138 39 39 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HSD17B11 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 Not Cancer Driver No 1 hippie, biogrid 28 3 0 0 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie 73 282 35 35 0
IL7 IL7 P13232 Interleukin-7 chr8 Not Cancer Driver No 1 hippie, biogrid 29 19 4 4 0
KCNC3 KCNC3 Q14003 Potassium voltage-gated channel subfamily C member 3 chr19 Not Cancer Driver No 1 hippie, biogrid 76 405 29 29 4
KCNG4 KCNG4 Q8TDN1 Potassium voltage-gated channel subfamily G member 4 chr16 Not Cancer Driver No 1 hippie, biogrid 117 47 10 10 0
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie, biogrid 40 9 0 0 0
LMAN2 LMAN2 Q12907 Vesicular integral-membrane protein VIP36 chr5 Not Cancer Driver No 1 hippie, biogrid 53 36 8 8 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
LRRN2_ENST00000367177 LRRN2 O75325 Leucine-rich repeat neuronal protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 132 84 18 18 0
MAGI1 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie 260 1212 220 220 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 1 hippie 39 25 1 1 0
METTL7A_ENST00000332160 METTL7A Q9H8H3 Putative methyltransferase-like protein 7A chr12 Not Cancer Driver No 1 hippie, biogrid 31 0 0 0 0
MGAT4C_ENST00000620241 MGAT4C Q9UBM8 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C chr12 Not Cancer Driver No 1 hippie, biogrid 179 29 19 19 0
NEDD8-MDP1 NEDD8-MDP1 E9PL57 NEDD8-MDP1 readthrough (Fragment) chr14 Not Cancer Driver No 1 biogrid 28 55 13 13 0
NFYA NFYA P23511 Nuclear transcription factor Y subunit alpha chr6 Not Cancer Driver No 1 hippie 43 187 29 29 0
NFYC NFYC Q13952 Nuclear transcription factor Y subunit gamma chr1 Not Cancer Driver No 1 hippie 46 320 32 32 0
NNMT NNMT P40261 Nicotinamide N-methyltransferase chr11 Not Cancer Driver No 1 hippie 51 5 1 1 0
OS9 OS9 Q13438 Protein OS-9 chr12 Not Cancer Driver No 2 hippie, biogrid 72 451 49 49 0
PARG_ENST00000616448 PARG Q86W56 Poly(ADP-ribose) glycohydrolase chr10 Not Cancer Driver No 1 hippie 60 519 1 1 0
PCDH20 PCDH20 Q8N6Y1 Protocadherin-20 chr13 Not Cancer Driver No 2 hippie, biogrid 228 159 30 30 0
PCDHAC1 PCDHAC1 Q9H158 Protocadherin alpha-C1 chr5 Not Cancer Driver No 2 hippie, biogrid 255 386 92 92 0
PCDHB11 PCDHB11 Q9Y5F2 Protocadherin beta-11 chr5 Not Cancer Driver No 1 hippie, biogrid 230 91 19 19 0
PCDHB16 PCDHB16 Q9NRJ7 Protocadherin beta-16 chr5 Not Cancer Driver No 1 hippie, biogrid 214 247 70 70 0
PCDHGA7 PCDHGA7 Q9Y5G6 Protocadherin gamma-A7 chr5 Not Cancer Driver No 1 hippie, biogrid 216 354 60 60 0
PCDHGC5 PCDHGC5 Q9Y5F6 Protocadherin gamma-C5 chr5 Not Cancer Driver No 1 hippie, biogrid 135 492 72 72 0
PDE3A PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A chr12 Not Cancer Driver No 1 hippie, biogrid 274 527 114 114 6
PEX14 PEX14 O75381 Peroxisomal membrane protein PEX14 chr1 Not Cancer Driver No 1 hippie, biogrid 38 266 28 28 0
PIGH PIGH Q14442 Phosphatidylinositol N-acetylglucosaminyltransferase subunit H chr14 Not Cancer Driver No 1 hippie, biogrid 12 1 0 0 1
PLGRKT PLGRKT Q9HBL7 Plasminogen receptor (KT) chr9 Not Cancer Driver No 1 hippie 17 0 0 0 0
POU5F1 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 Census Yes 1 hippie 36 186 12 12 0
PTRH2_ENST00000470557 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 Not Cancer Driver No 1 hippie 14 19 2 2 1
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 biogrid 27 11 0 0 4
RARRES1 RARRES1 P49788 Retinoic acid receptor responder protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 24 79 3 3 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 Not Cancer Driver No 1 hippie 63 143 20 20 0
RNF139 RNF139 Q8WU17 E3 ubiquitin-protein ligase RNF139 chr8 Not Cancer Driver No 1 hippie 76 68 4 4 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 Not Cancer Driver No 1 hippie 77 471 66 66 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie, biogrid 50 69 3 3 0
SAR1A_ENST00000373238 SAR1A Q9NR31 GTP-binding protein SAR1a chr10 Not Cancer Driver No 1 hippie 23 4 0 0 0
SEC62 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 2 hippie, biogrid 41 211 23 23 0
SEC63 SEC63 Q9UGP8 Translocation protein SEC63 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 98 266 37 37 0
SH3TC1 SH3TC1 Q8TE82 SH3 domain and tetratricopeptide repeat-containing protein 1 chr4 Not Cancer Driver No 1 hippie 160 233 32 32 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SPARC SPARC P09486 SPARC chr5 Not Cancer Driver No 1 hippie, biogrid 60 69 5 5 2
SPPL2B SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 Not Cancer Driver No 1 hippie, biogrid 68 99 17 17 0
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 Not Cancer Driver No 1 hippie 124 357 43 43 0
SRF SRF P11831 Serum response factor chr6 Not Cancer Driver No 1 hippie 44 443 42 42 0
SSR1 SSR1 P43307 Translocon-associated protein subunit alpha chr6 Not Cancer Driver No 1 hippie, biogrid 26 114 10 10 0
ST7 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 hippie 62 64 5 5 0
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 Not Cancer Driver No 1 hippie, biogrid 70 387 45 45 13
STK40_ENST00000373132 STK40 Q8N2I9 Serine/threonine-protein kinase 40 chr1 Not Cancer Driver No 2 hippie, biogrid 50 103 9 9 0
STX4 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 50 152 20 20 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 Not Cancer Driver No 1 hippie 63 284 32 32 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 31 56 4 4 1
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 1 hippie 58 111 15 15 12
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 Not Cancer Driver No 1 hippie, biogrid 47 91 5 5 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 hippie 105 203 10 10 39
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 Not Cancer Driver No 1 hippie 19 169 9 9 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 Not Cancer Driver No 1 hippie 37 336 26 26 2
ZYG11A ZYG11A Q6WRX3 Protein zyg-11 homolog A chr1 Not Cancer Driver No 1 hippie, biogrid 52 7 0 0 0