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ATAD3A ,ATAD3A ,Q9NVI7
  • Number of Interaction partner in intact: 171
  • Number of Interaction partner in biogrid: 70
  • Number of Interaction partner in hippie: 420
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AARS2 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 123 203 25 25 5
AATK AATK Q6ZMQ8 Serine/threonine-protein kinase LMTK1 chr17 Not Cancer Driver No 2 intact, hippie 108 912 75 75 0
ABCB7_ENST00000373394 ABCB7 O75027 Iron-sulfur clusters transporter ABCB7, mitochondrial chrX Not Cancer Driver No 1 intact, hippie 117 79 14 14 4
ACAD9 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 69 28 5 5 12
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
AFG3L2 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 Not Cancer Driver No 1 intact, hippie 72 162 10 10 22
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 2 intact, hippie, biogrid 88 166 22 22 11
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
ANKRD55 ANKRD55 Q3KP44 Ankyrin repeat domain-containing protein 55 chr5 Not Cancer Driver No 1 hippie 95 339 63 63 0
APOO APOO Q9BUR5 MICOS complex subunit MIC26 chrX Not Cancer Driver No 1 hippie, biogrid 25 23 4 4 0
ARL2 ARL2 P36404 ADP-ribosylation factor-like protein 2 chr11 Not Cancer Driver No 1 intact, hippie 19 0 0 0 1
ASXL1_ENST00000613218 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 Census, Compendium Yes 1 hippie 205 1300 174 174 0
ATAD3A ATAD3A Q9NVI7 ATPase family AAA domain-containing protein 3A chr1 Not Cancer Driver No 1 intact, hippie 66 269 24 24 2
ATAD3B ATAD3B Q5T9A4 ATPase family AAA domain-containing protein 3B chr1 Not Cancer Driver No 1 hippie 84 243 19 19 0
ATP5MD_ENST00000309579 ATP5MK Q96IX5 ATP synthase membrane subunit K, mitochondrial chr10 Not Cancer Driver No 1 intact 7 1 1 1 0
ATP5MG ATP5MG O75964 ATP synthase subunit g, mitochondrial chr11 Not Cancer Driver No 1 hippie 16 0 0 0 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie 51 63 8 8 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 Not Cancer Driver No 1 hippie 14 163 14 14 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BRAF BRAF P15056 Serine/threonine-protein kinase B-raf chr7 Census, Compendium Yes 1 intact, hippie 791 310 43 43 39
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
BRF2 BRF2 Q9HAW0 Transcription factor IIIB 50 kDa subunit chr8 Not Cancer Driver No 1 hippie 40 138 13 13 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
C15orf48_ENST00000396650 NMES1 Q9C002 Normal mucosa of esophagus-specific gene 1 protein chr15 Not Cancer Driver No 1 intact 14 10 1 1 0
C17orf80_ENST00000535032 C17orf80 Q9BSJ5 Uncharacterized protein C17orf80 chr17 Not Cancer Driver No 1 hippie, biogrid 64 455 53 53 0
C19orf70_ENST00000309324 MICOS13 Q5XKP0 MICOS complex subunit MIC13 chr19 Not Cancer Driver No 1 hippie 12 3 0 0 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 14 103 6 6 2
CALR3 CALR3 Q96L12 Calreticulin-3 chr19 Not Cancer Driver No 1 hippie 60 101 16 16 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CCDC90B CCDC90B Q9GZT6 Coiled-coil domain-containing protein 90B, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 31 76 6 6 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 Not Cancer Driver No 1 hippie 85 495 61 61 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 Not Cancer Driver No 1 intact, hippie 73 95 12 12 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie 50 34 2 2 0
CEP57 CEP57 Q86XR8 Centrosomal protein of 57 kDa chr11 Not Cancer Driver No 1 hippie 61 403 50 50 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact, hippie 287 145 18 18 151
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie 235 1015 122 122 18
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1 hippie 419 974 177 177 6
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 Not Cancer Driver No 1 hippie, biogrid 59 17 3 3 0
CLUAP1_ENST00000576634 CLUAP1 Q96AJ1 Clusterin-associated protein 1 chr16 Not Cancer Driver No 1 hippie 48 203 22 22 0
COA1 COA1 Q9GZY4 Cytochrome c oxidase assembly factor 1 homolog chr7 Not Cancer Driver No 1 intact, hippie 14 4 1 1 0
COA3 COA3 Q9Y2R0 Cytochrome c oxidase assembly factor 3 homolog, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 4 57 3 3 0
COIL COIL P38432 Coilin chr17 Not Cancer Driver No 1 hippie, biogrid 61 385 42 42 0
COPB1_ENST00000439561 COPB1 P53618 Coatomer subunit beta chr11 Not Cancer Driver No 1 hippie, biogrid 110 95 10 10 1
COQ2_ENST00000647002 COQ2 Q96H96 4-hydroxybenzoate polyprenyltransferase, mitochondrial chr4 Not Cancer Driver No 1 intact, hippie, biogrid 23 25 0 0 17
COQ8A COQ8A Q8NI60 Atypical kinase COQ8A, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 95 166 29 29 12
COQ8B COQ8B Q96D53 Atypical kinase COQ8B, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 53 117 15 15 8
COQ9 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 43 111 13 13 0
COX15 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 2 intact, hippie, biogrid 48 0 0 0 2
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 17 5 1 1 1
COX6B1_ENST00000592141 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 1 hippie 15 23 6 6 2
COX8A COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CPEB1_ENST00000611031 CPEB1 Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 chr15 Not Cancer Driver No 1 intact, hippie 90 226 37 37 0
CS CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 2 hippie, biogrid 50 13 2 2 0
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 1 hippie 44 46 3 3 0
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 Not Cancer Driver No 1 hippie 62 133 18 18 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 intact, hippie 151 65 9 9 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
CUL9 CUL9 Q8IWT3 Cullin-9 chr6 Not Cancer Driver No 1 hippie 321 633 73 73 0
CYC1 CYC1 P08574 Cytochrome c1, heme protein, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 65 35 8 8 2
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DAP3_ENST00000343043 DAP3 P51398 28S ribosomal protein S29, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 58 82 14 14 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 48 53 6 6 1
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX28 DDX28 Q9NUL7 Probable ATP-dependent RNA helicase DDX28 chr16 Not Cancer Driver No 1 intact, hippie 37 127 3 3 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 49 34 8 8 0
DHODH DHODH Q02127 Dihydroorotate dehydrogenase (quinone), mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 44 96 11 11 10
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 Not Cancer Driver No 1 hippie, biogrid 62 54 8 8 1
DLST DLST P36957 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 Not Cancer Driver No 1 intact, hippie, biogrid 53 190 32 32 1
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 50 152 21 21 0
DNAJC11 DNAJC11 Q9NVH1 DnaJ homolog subfamily C member 11 chr1 Not Cancer Driver No 1 intact, hippie 66 123 14 14 0
DNAJC15 DNAJC15 Q9Y5T4 DnaJ homolog subfamily C member 15 chr13 Not Cancer Driver No 1 hippie, biogrid 19 25 4 4 0
DNAJC30 DNAJC30 Q96LL9 DnaJ homolog subfamily C member 30, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 25 83 7 7 3
DNAJC4_ENST00000321685 DNAJC4 Q9NNZ3 DnaJ homolog subfamily C member 4 chr11 Not Cancer Driver No 1 hippie, biogrid 19 180 13 13 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 Not Cancer Driver No 1 hippie 67 212 23 23 7
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 151 8 1 1 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 Not Cancer Driver No 1 hippie 96 514 64 64 0
E2F3 E2F3 O00716 Transcription factor E2F3 chr6 Not Cancer Driver No 1 intact, hippie 46 253 20 20 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EPB41L3 EPB41L3 Q9Y2J2 Band 4.1-like protein 3 chr18 Not Cancer Driver No 1 intact, hippie 298 695 207 207 0
ERAL1 ERAL1 O75616 GTPase Era, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 32 81 6 6 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 Not Cancer Driver No 1 hippie 90 35 7 7 4
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 58 176 15 15 0
FAM160B1 FHIP2A Q5W0V3 FHF complex subunit HOOK interacting protein 2A chr10 Not Cancer Driver No 1 intact 92 130 13 13 0
FAM160B2 FHIP2B Q86V87 FHF complex subunit HOOK interacting protein 2B chr8 Not Cancer Driver No 1 intact 75 139 14 14 0
FAM210A FAM210A Q96ND0 Protein FAM210A chr18 Not Cancer Driver No 1 intact, hippie 34 99 14 14 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FASTKD2_ENST00000402774 FASTKD2 Q9NYY8 FAST kinase domain-containing protein 2, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 74 30 2 2 0
FASTKD5 FASTKD5 Q7L8L6 FAST kinase domain-containing protein 5, mitochondrial chr20 Not Cancer Driver No 1 hippie, biogrid 86 94 8 8 0
FBXO25 FBXO25 Q8TCJ0 F-box only protein 25 chr8 Not Cancer Driver No 1 hippie 33 20 0 0 0
FBXO32 FBXO32 Q969P5 F-box only protein 32 chr8 Not Cancer Driver No 1 hippie 54 0 0 0 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 Not Cancer Driver No 1 hippie 75 243 38 38 1
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 Not Cancer Driver No 1 hippie 68 120 4 4 0
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 Census, Compendium Yes 1 intact 238 228 44 44 72
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 Not Cancer Driver No 1 hippie 85 52 8 8 0
FMC1 FMC1 Q96HJ9 Protein FMC1 homolog chr7 Not Cancer Driver No 1 intact, hippie 9 30 1 1 0
FMNL1 FMNL1 O95466 Formin-like protein 1 chr17 Not Cancer Driver No 1 hippie 115 524 32 32 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 2 intact, hippie 85 352 65 65 0
GADD45GIP1 GADD45GIP1 Q8TAE8 Growth arrest and DNA damage-inducible proteins-interacting protein 1 chr19 Not Cancer Driver No 1 hippie 19 193 19 19 0
GAN GAN Q9H2C0 Gigaxonin chr16 Not Cancer Driver No 1 hippie 74 33 6 6 19
GLUD1 GLUD1 P00367 Glutamate dehydrogenase 1, mitochondrial chr10 Not Cancer Driver No 1 intact, hippie 50 107 14 14 13
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 Not Cancer Driver No 1 intact, hippie 108 83 7 7 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
GRK2 GRK2 P25098 Beta-adrenergic receptor kinase 1 chr11 Not Cancer Driver No 1 hippie 77 87 8 8 0
GRWD1 GRWD1 Q9BQ67 Glutamate-rich WD repeat-containing protein 1 chr19 Not Cancer Driver No 1 hippie 44 187 14 14 0
GTPBP10 GTPBP10 A4D1E9 GTP-binding protein 10 chr7 Not Cancer Driver No 1 intact, hippie 50 52 4 4 0
GUF1 GUF1 Q8N442 Translation factor GUF1, mitochondrial chr4 Not Cancer Driver No 1 intact, hippie 75 38 5 5 1
HADHA HADHA P40939 Trifunctional enzyme subunit alpha, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 72 19 2 2 5
HADHB HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 71 41 9 9 14
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX Not Cancer Driver No 1 intact, hippie 178 409 59 59 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 1 intact, hippie 35 203 29 29 0
HECTD1 HECTD1 Q9ULT8 E3 ubiquitin-protein ligase HECTD1 chr14 Not Cancer Driver No 1 hippie 274 991 108 108 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie 37 77 9 9 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 118 435 51 51 0
HIGD1A_ENST00000418900 HIGD1A Q9Y241 HIG1 domain family member 1A, mitochondrial chr3 Not Cancer Driver No 1 hippie 17 8 0 0 0
HINT2 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 1 hippie, biogrid 10 29 2 2 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 hippie, biogrid 36 25 6 6 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 61 82 6 6 2
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 Compendium Yes 1 hippie 44 127 9 9 2
IARS2 IARS2 Q9NSE4 Isoleucine--tRNA ligase, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 149 145 22 22 0
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie 45 71 9 9 0
IMMP1L IMMP1L Q96LU5 Mitochondrial inner membrane protease subunit 1 chr11 Not Cancer Driver No 1 hippie 20 3 0 0 0
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 36 29 7 7 0
INAVA_ENST00000367342 INAVA Q3KP66 Innate immunity activator protein chr1 Not Cancer Driver No 1 intact, hippie 112 553 98 98 1
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 254 97 27 27 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KCTD10 KCTD10 Q9H3F6 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 chr12 Not Cancer Driver No 1 hippie 68 73 19 19 0
KCTD12 KCTD12 Q96CX2 BTB/POZ domain-containing protein KCTD12 chr13 Not Cancer Driver No 1 hippie 15 147 4 4 0
KIAA0391 PRORP O15091 Mitochondrial ribonuclease P catalytic subunit chr14 Not Cancer Driver No 1 intact 62 60 12 12 0
KIAA0556 KATNIP O60303 Katanin-interacting protein chr16 Not Cancer Driver No 1 intact 240 982 137 137 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KLF15 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 Not Cancer Driver No 1 hippie 66 273 48 48 0
KLF16 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 intact, hippie 13 204 8 8 0
KLF4 KLF4 O43474-1 Isoform 2 of Krueppel-like factor 4 chr9 Census, Compendium Yes 1 intact, hippie 58 415 38 38 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 Compendium Yes 1 hippie 77 366 40 40 0
KLF8 KLF8 O95600 Krueppel-like factor 8 chrX Not Cancer Driver No 1 intact, hippie 71 270 53 53 0
L1TD1 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie 149 534 114 114 0
L3MBTL1 L3MBTL1 Q9Y468 Lethal(3)malignant brain tumor-like protein 1 chr20 Not Cancer Driver No 1 intact, hippie 116 447 40 40 0
LACTB LACTB P83111 Serine beta-lactamase-like protein LACTB, mitochondrial chr15 Not Cancer Driver No 1 intact, hippie 44 121 3 3 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LETMD1_ENST00000262055 LETMD1 Q6P1Q0 LETM1 domain-containing protein 1 chr12 Not Cancer Driver No 1 intact, hippie 49 0 0 0 0
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 Not Cancer Driver No 1 hippie 108 16 3 3 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 99 175 15 15 10
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 131 18 2 2 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
MAFB MAFB Q9Y5Q3 Transcription factor MafB chr20 Census Yes 1 hippie 35 301 34 34 10
MAIP1 MAIP1 Q8WWC4 m-AAA protease-interacting protein 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 28 12 0 0 0
MALSU1 MALSU1 Q96EH3 Mitochondrial assembly of ribosomal large subunit protein 1 chr7 Not Cancer Driver No 1 intact, hippie 17 34 0 0 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 Census, Compendium Yes 1 hippie 94 96 24 24 6
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 Not Cancer Driver No 1 hippie 197 242 29 29 0
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 79 165 20 20 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 Not Cancer Driver No 1 intact, hippie 92 490 50 50 0
MATR3_ENST00000509990 MATR3 P43243 Matrin-3 chr5 Not Cancer Driver No 1 hippie 98 611 68 68 3
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MCU MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 41 13 0 0 0
MCUB MCUB Q9NWR8 Calcium uniporter regulatory subunit MCUb, mitochondrial chr4 Not Cancer Driver No 1 intact, hippie 33 24 1 1 0
MDH2 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 39 8 1 1 3
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie 76 446 42 42 0
METTL17_ENST00000339374 METTL17 Q9H7H0 Methyltransferase-like protein 17, mitochondrial chr14 Not Cancer Driver No 1 hippie 62 95 16 16 0
MEX3C MEX3C Q5U5Q3 RNA-binding E3 ubiquitin-protein ligase MEX3C chr18 Not Cancer Driver No 1 hippie 54 475 32 32 0
MGAT2 MGAT2 Q10469 Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase chr14 Not Cancer Driver No 1 intact, hippie 31 30 3 3 3
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 540 3169 529 529 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 Census Yes 1 hippie 92 208 22 22 85
MRPL1 MRPL1 Q9BYD6 39S ribosomal protein L1, mitochondrial chr4 Not Cancer Driver No 1 hippie 44 46 5 5 0
MRPL11 MRPL11 Q9Y3B7 39S ribosomal protein L11, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 25 12 1 1 0
MRPL12 MRPL12 P52815 39S ribosomal protein L12, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 21 22 6 6 1
MRPL13 MRPL13 Q9BYD1 39S ribosomal protein L13, mitochondrial chr8 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
MRPL14 MRPL14 Q6P1L8 39S ribosomal protein L14, mitochondrial chr6 Not Cancer Driver No 1 intact, hippie 21 36 6 6 0
MRPL15 MRPL15 Q9P015 39S ribosomal protein L15, mitochondrial chr8 Not Cancer Driver No 1 intact, hippie 32 81 3 3 0
MRPL16 MRPL16 Q9NX20 39S ribosomal protein L16, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 38 57 11 11 0
MRPL17 MRPL17 Q9NRX2 39S ribosomal protein L17, mitochondrial chr11 Not Cancer Driver No 1 hippie 13 39 2 2 0
MRPL18 MRPL18 Q9H0U6 39S ribosomal protein L18, mitochondrial chr6 Not Cancer Driver No 1 intact, hippie 26 35 2 2 0
MRPL2 MRPL2 Q5T653 39S ribosomal protein L2, mitochondrial chr6 Not Cancer Driver No 1 intact, hippie 43 132 17 17 0
MRPL20 MRPL20 Q9BYC9 39S ribosomal protein L20, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 20 0 0 0 0
MRPL21 MRPL21 Q7Z2W9 39S ribosomal protein L21, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 25 20 0 0 0
MRPL22 MRPL22 Q9NWU5 39S ribosomal protein L22, mitochondrial chr5 Not Cancer Driver No 1 intact, hippie 23 28 2 2 0
MRPL23 MRPL23 Q16540 39S ribosomal protein L23, mitochondrial chr11 Not Cancer Driver No 1 hippie 29 68 12 12 0
MRPL24_ENST00000368211 MRPL24 Q96A35 39S ribosomal protein L24, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 22 71 7 7 0
MRPL27 MRPL27 Q9P0M9 39S ribosomal protein L27, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 16 35 2 2 0
MRPL28_ENST00000389675 MRPL28 Q13084 39S ribosomal protein L28, mitochondrial chr16 Not Cancer Driver No 1 hippie 21 52 3 3 0
MRPL3 MRPL3 P09001 39S ribosomal protein L3, mitochondrial chr3 Not Cancer Driver No 1 hippie 42 61 5 5 1
MRPL32 MRPL32 Q9BYC8 39S ribosomal protein L32, mitochondrial chr7 Not Cancer Driver No 1 hippie 35 91 15 15 0
MRPL33 MRPL33 O75394 39S ribosomal protein L33, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 8 0 0 0 0
MRPL34 MRPL34 Q9BQ48 39S ribosomal protein L34, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 7 37 3 3 0
MRPL35 MRPL35 Q9NZE8 39S ribosomal protein L35, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 25 17 3 3 0
MRPL37_ENST00000360840 MRPL37 Q9BZE1 39S ribosomal protein L37, mitochondrial chr1 Not Cancer Driver No 1 hippie 44 36 5 5 0
MRPL38 MRPL38 Q96DV4 39S ribosomal protein L38, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 41 88 13 13 0
MRPL39_ENST00000352957 MRPL39 Q9NYK5 39S ribosomal protein L39, mitochondrial chr21 Not Cancer Driver No 1 intact, hippie 41 38 6 6 0
MRPL40 MRPL40 Q9NQ50 39S ribosomal protein L40, mitochondrial chr22 Not Cancer Driver No 1 hippie 20 104 9 9 0
MRPL41 MRPL41 Q8IXM3 39S ribosomal protein L41, mitochondrial chr9 Not Cancer Driver No 1 hippie 18 23 1 1 0
MRPL42 MRPL42 Q9Y6G3 39S ribosomal protein L42, mitochondrial chr12 Not Cancer Driver No 1 hippie 18 52 5 5 0
MRPL43_ENST00000318325 MRPL43 Q8N983 39S ribosomal protein L43, mitochondrial chr10 Not Cancer Driver No 1 hippie 17 66 6 6 0
MRPL44 MRPL44 Q9H9J2 39S ribosomal protein L44, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 37 45 2 2 1
MRPL46 MRPL46 Q9H2W6 39S ribosomal protein L46, mitochondrial chr15 Not Cancer Driver No 1 hippie 24 58 0 0 0
MRPL47 MRPL47 Q9HD33 39S ribosomal protein L47, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 44 34 7 7 0
MRPL48 MRPL48 Q96GC5 39S ribosomal protein L48, mitochondrial chr11 Not Cancer Driver No 1 hippie 16 15 1 1 0
MRPL49 MRPL49 Q13405 39S ribosomal protein L49, mitochondrial chr11 Not Cancer Driver No 1 hippie 17 74 9 9 0
MRPL4_ENST00000307422 MRPL4 Q9BYD3 39S ribosomal protein L4, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 29 105 14 14 0
MRPL50 MRPL50 Q8N5N7 39S ribosomal protein L50, mitochondrial chr9 Not Cancer Driver No 1 hippie 27 3 0 0 0
MRPL51 MRPL51 Q4U2R6 39S ribosomal protein L51, mitochondrial chr12 Not Cancer Driver No 1 hippie 15 0 0 0 0
MRPL53 MRPL53 Q96EL3 39S ribosomal protein L53, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 20 22 1 1 0
MRPL55_ENST00000366746 MRPL55 Q7Z7F7 39S ribosomal protein L55, mitochondrial chr1 Not Cancer Driver No 1 hippie 19 67 13 13 0
MRPL57 MRPL57 Q9BQC6 Ribosomal protein 63, mitochondrial chr13 Not Cancer Driver No 1 intact, hippie 11 9 1 1 0
MRPL58 MRPL58 Q14197 Peptidyl-tRNA hydrolase ICT1, mitochondrial chr17 Not Cancer Driver No 1 hippie 28 105 13 13 0
MRPL9 MRPL9 Q9BYD2 39S ribosomal protein L9, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 24 54 3 3 0
MRPS10 MRPS10 P82664 28S ribosomal protein S10, mitochondrial chr6 Not Cancer Driver No 1 intact, hippie 19 22 3 3 0
MRPS11 MRPS11 P82912 28S ribosomal protein S11, mitochondrial chr15 Not Cancer Driver No 1 intact, hippie 23 114 12 12 0
MRPS12_ENST00000402029 MRPS12 O15235 28S ribosomal protein S12, mitochondrial chr19 Not Cancer Driver No 1 hippie 18 59 11 11 0
MRPS14 MRPS14 O60783 28S ribosomal protein S14, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 26 4 1 1 1
MRPS15 MRPS15 P82914 28S ribosomal protein S15, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 35 72 7 7 0
MRPS16 MRPS16 Q9Y3D3 28S ribosomal protein S16, mitochondrial chr10 Not Cancer Driver No 1 intact, hippie 7 29 2 2 0
MRPS17 MRPS17 Q9Y2R5 28S ribosomal protein S17, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie 14 9 3 3 0
MRPS18A MRPS18A Q9NVS2 39S ribosomal protein S18a, mitochondrial chr6 Not Cancer Driver No 1 hippie 18 82 5 5 0
MRPS18B MRPS18B Q9Y676 28S ribosomal protein S18b, mitochondrial chr6 Not Cancer Driver No 1 hippie 31 112 12 12 0
MRPS18C MRPS18C Q9Y3D5 28S ribosomal protein S18c, mitochondrial chr4 Not Cancer Driver No 1 intact, hippie 16 5 1 1 0
MRPS2 MRPS2 Q9Y399 28S ribosomal protein S2, mitochondrial chr9 Not Cancer Driver No 1 intact, hippie 32 57 6 6 3
MRPS21_ENST00000614145 MRPS21 P82921 28S ribosomal protein S21, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 18 0 0 0 0
MRPS22 MRPS22 P82650 28S ribosomal protein S22, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 51 65 8 8 1
MRPS23 MRPS23 Q9Y3D9 28S ribosomal protein S23, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 21 58 6 6 1
MRPS24 MRPS24 Q96EL2 28S ribosomal protein S24, mitochondrial chr7 Not Cancer Driver No 1 hippie 20 1 0 0 0
MRPS25 MRPS25 P82663 28S ribosomal protein S25, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 24 38 5 5 1
MRPS26 MRPS26 Q9BYN8 28S ribosomal protein S26, mitochondrial chr20 Not Cancer Driver No 1 hippie 18 102 6 6 0
MRPS27_ENST00000261413 MRPS27 Q92552 28S ribosomal protein S27, mitochondrial chr5 Not Cancer Driver No 1 intact, hippie 46 51 7 7 0
MRPS28 MRPS28 Q9Y2Q9 28S ribosomal protein S28, mitochondrial chr8 Not Cancer Driver No 1 hippie 26 78 8 8 1
MRPS30 MRPS30 Q9NP92 39S ribosomal protein S30, mitochondrial chr5 Not Cancer Driver No 1 intact, hippie 54 53 10 10 0
MRPS31 MRPS31 Q92665 28S ribosomal protein S31, mitochondrial chr13 Not Cancer Driver No 1 hippie 46 231 28 28 0
MRPS33 MRPS33 Q9Y291 28S ribosomal protein S33, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie 11 37 8 8 0
MRPS34_ENST00000397375 MRPS34 P82930 28S ribosomal protein S34, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 13 56 2 2 1
MRPS35 MRPS35 P82673 28S ribosomal protein S35, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie 42 92 13 13 0
MRPS5 MRPS5 P82675 28S ribosomal protein S5, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 52 157 20 20 0
MRPS6 MRPS6 P82932 28S ribosomal protein S6, mitochondrial chr21 Not Cancer Driver No 1 intact, hippie 17 13 1 1 0
MRPS7 MRPS7 Q9Y2R9 28S ribosomal protein S7, mitochondrial chr17 Not Cancer Driver No 1 hippie 31 26 0 0 1
MRPS9 MRPS9 P82933 28S ribosomal protein S9, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 49 75 9 9 0
MRS2_ENST00000378386 MRS2 Q9HD23 Magnesium transporter MRS2 homolog, mitochondrial chr6 Not Cancer Driver No 1 intact, hippie 47 0 0 0 0
MTCH1 MTCH1 Q9NZJ7 Mitochondrial carrier homolog 1 chr6 Not Cancer Driver No 1 hippie, biogrid 31 102 2 2 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie, biogrid 45 11 0 0 0
MTERF3 MTERF3 Q96E29 Transcription termination factor 3, mitochondrial chr8 Not Cancer Driver No 1 intact, hippie 53 62 5 5 0
MTF1 MTF1 Q14872 Metal regulatory transcription factor 1 chr1 Not Cancer Driver No 1 hippie 115 553 76 76 0
MTG2 MTG2 Q9H4K7 Mitochondrial ribosome-associated GTPase 2 chr20 Not Cancer Driver No 1 intact, hippie 57 47 9 9 0
MTMR4 MTMR4 Q9NYA4 Myotubularin-related protein 4 chr17 Not Cancer Driver No 1 hippie 147 474 59 59 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NCAPD3 NCAPD3 P42695 Condensin-2 complex subunit D3 chr11 Not Cancer Driver No 1 hippie 193 304 42 42 1
NDUFA12 NDUFA12 Q9UI09 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 chr12 Not Cancer Driver No 1 intact, hippie 18 31 6 6 0
NDUFA4 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 Not Cancer Driver No 1 hippie, biogrid 14 4 0 0 0
NDUFA6_ENST00000602404 NDUFA6 P56556 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 chr22 Not Cancer Driver No 1 hippie 10 14 2 2 1
NDUFA9 NDUFA9 Q16795 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial chr12 Not Cancer Driver No 1 hippie 57 8 0 0 2
NDUFAF4 NDUFAF4 Q9P032 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 chr6 Not Cancer Driver No 1 hippie 14 46 4 4 2
NDUFB10 NDUFB10 O96000 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 chr16 Not Cancer Driver No 1 intact, hippie 19 33 1 1 1
NDUFB8 NDUFB8 O95169 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 28 64 11 11 3
NDUFS4 NDUFS4 O43181 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 26 92 17 17 1
NEURL4 NEURL4 Q96JN8 Neuralized-like protein 4 chr17 Not Cancer Driver No 1 intact, hippie 217 751 119 119 0
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 69 252 26 26 16
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 1 intact, hippie 104 344 38 38 0
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 155 24 0 0 150
NPRL2 NPRL2 Q8WTW4 GATOR complex protein NPRL2 chr3 Compendium Yes 1 hippie 37 10 3 3 1
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUBPL NUBPL Q8TB37 Iron-sulfur protein NUBPL chr14 Not Cancer Driver No 1 intact, hippie 32 49 1 1 2
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
OASL OASL Q15646 2'-5'-oligoadenylate synthase-like protein chr12 Not Cancer Driver No 1 intact, hippie 76 8 4 4 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OCIAD1 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 2 hippie, biogrid 37 169 25 25 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
OMA1 OMA1 Q96E52 Metalloendopeptidase OMA1, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 52 34 4 4 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 114 131 17 17 60
OPA3_ENST00000263275 OPA3 Q9H6K4 Optic atrophy 3 protein chr19 Not Cancer Driver No 1 hippie 18 44 7 7 2
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 Not Cancer Driver No 1 hippie 69 208 29 29 0
PARL PARL Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 49 28 5 5 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 Not Cancer Driver No 1 hippie 137 99 7 7 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 2 hippie, biogrid 70 43 6 6 20
PEX3 PEX3 P56589 Peroxisomal biogenesis factor 3 chr6 Not Cancer Driver No 1 hippie, biogrid 31 24 0 0 2
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 2 hippie, biogrid 31 26 4 4 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 Not Cancer Driver No 1 intact 37 4 1 1 0
PHKG2 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 Not Cancer Driver No 1 hippie 48 50 6 6 4
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 hippie 154 268 61 61 2
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PMPCA PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 1 hippie, biogrid 67 23 3 3 4
PMS2 PMS2 P54278 Mismatch repair endonuclease PMS2 chr7 Census, Compendium Yes 1 hippie 117 331 44 44 9
POC5 POC5 Q8NA72 Centrosomal protein POC5 chr5 Not Cancer Driver No 1 hippie 64 352 46 46 0
POLRMT POLRMT O00411 DNA-directed RNA polymerase, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 188 253 31 31 0
PPEF1 PPEF1 O14829 Serine/threonine-protein phosphatase with EF-hands 1 chrX Not Cancer Driver No 1 intact, hippie 127 66 10 10 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 intact, hippie 38 27 6 6 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 intact, hippie 26 23 4 4 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 Not Cancer Driver No 1 hippie 83 628 72 72 0
PPP2R2C_ENST00000382599 PPP2R2C Q9Y2T4 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform chr4 Not Cancer Driver No 1 intact, hippie 78 78 13 13 0
PPP2R2D PPP2R2D Q66LE6 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform chr10 Not Cancer Driver No 1 hippie 50 65 9 9 0
PPP4C_ENST00000561610 PPP4C P60510 Serine/threonine-protein phosphatase 4 catalytic subunit chr16 Not Cancer Driver No 1 hippie 41 0 0 0 0
PRDM16 PRDM16 Q9HAZ2 Histone-lysine N-methyltransferase PRDM16 chr1 Census Yes 1 hippie 254 830 152 152 1
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 72 124 17 17 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
PRKACB_ENST00000370689 PRKACB P22694 cAMP-dependent protein kinase catalytic subunit beta chr1 Not Cancer Driver No 1 hippie 50 26 6 6 4
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 Compendium Yes 1 hippie 79 43 9 9 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 83 694 57 57 0
PSMD6_ENST00000295901 PSMD6 Q15008 26S proteasome non-ATPase regulatory subunit 6 chr3 Not Cancer Driver No 1 intact, hippie 33 40 3 3 0
PSME1_ENST00000206451 PSME1 Q06323 Proteasome activator complex subunit 1 chr14 Not Cancer Driver No 1 hippie, biogrid 20 80 8 8 0
PTCD3 PTCD3 Q96EY7 Pentatricopeptide repeat domain-containing protein 3, mitochondrial chr2 Not Cancer Driver No 1 hippie 69 77 4 4 0
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 Census Yes 1 hippie 42 12 0 0 0
PTP4A3_ENST00000521578 PTP4A3 O75365 Protein tyrosine phosphatase type IVA 3 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 30 3 0 0 0
PTPMT1 PTPMT1 Q8WUK0 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 16 0 0 0 0
PTPRM_ENST00000332175 PTPRM P28827 Receptor-type tyrosine-protein phosphatase mu chr18 Not Cancer Driver No 1 hippie 256 365 60 60 0
PTPRR PTPRR Q15256 Receptor-type tyrosine-protein phosphatase R chr12 Not Cancer Driver No 1 intact, hippie 172 73 28 28 0
PXMP2 PXMP2 Q9NR77 Peroxisomal membrane protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 15 0 0 0 0
RAB5IF_ENST00000373852 RAB5IF Q9BUV8 Respirasome Complex Assembly Factor 1 chr20 Not Cancer Driver No 1 hippie 7 13 0 0 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 1 intact, hippie 89 169 38 38 22
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie 52 19 2 2 0
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 18 10 0 0 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 41 12 3 3 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RIOK2 RIOK2 Q9BVS4 Serine/threonine-protein kinase RIO2 chr5 Not Cancer Driver No 1 hippie 68 253 33 33 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 Not Cancer Driver No 1 intact, hippie 66 295 39 39 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie 119 232 34 34 3
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 Not Cancer Driver No 1 hippie 142 319 45 45 0
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 2 hippie, biogrid 50 69 3 3 0
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 53 26 4 4 0
RPUSD4 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 54 97 15 15 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 1 intact, hippie 74 513 48 48 0
S100B S100B P04271 Protein S100-B chr21 Not Cancer Driver No 1 hippie, biogrid 17 13 1 1 0
SEC63 SEC63 Q9UGP8 Translocation protein SEC63 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 98 266 37 37 0
SETD9 SETD9 Q8NE22 SET domain-containing protein 9 chr5 Not Cancer Driver No 1 intact, hippie 28 4 1 1 0
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 hippie, biogrid 31 29 1 1 0
SH3KBP1 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 1 hippie 102 530 82 82 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SLC15A3 SLC15A3 Q8IY34 Solute carrier family 15 member 3 chr11 Not Cancer Driver No 1 intact, hippie 63 43 1 1 0
SLC25A1 SLC25A1 P53007 Tricarboxylate transport protein, mitochondrial chr22 Not Cancer Driver No 1 intact, hippie 22 34 2 2 17
SLC25A11 SLC25A11 Q02978 Mitochondrial 2-oxoglutarate/malate carrier protein chr17 Not Cancer Driver No 1 intact, hippie 37 16 1 1 3
SLC25A12 SLC25A12 O75746 Calcium-binding mitochondrial carrier protein Aralar1 chr2 Not Cancer Driver No 1 hippie, biogrid 110 21 7 7 2
SLC25A19_ENST00000416858 SLC25A19 Q9HC21 Mitochondrial thiamine pyrophosphate carrier chr17 Not Cancer Driver No 1 intact, hippie 34 16 0 0 2
SLC25A3 SLC25A3 Q00325 Phosphate carrier protein, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 49 32 4 4 1
SLC25A33 SLC25A33 Q9BSK2 Solute carrier family 25 member 33 chr1 Not Cancer Driver No 1 intact, hippie 23 4 0 0 0
SLC25A46 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 Not Cancer Driver No 1 hippie, biogrid 37 96 2 2 4
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 1 intact, hippie 41 0 0 0 0
SLC25A51_ENST00000242275 SLC25A51 Q9H1U9 Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 chr9 Not Cancer Driver No 1 hippie, biogrid 31 21 0 0 0
SLC25A6 SLC25A6 P12236 ADP/ATP translocase 3 chrX Not Cancer Driver No 1 intact, hippie 41 0 0 0 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 52 97 11 11 0
SOAT1 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 73 49 4 4 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 Census, Compendium Yes 1 intact, hippie 22 66 3 3 2
SOX15_ENST00000538513 SOX15 O60248 Protein SOX-15 chr17 Not Cancer Driver No 1 intact, hippie 18 227 18 18 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 intact, hippie 39 312 39 39 0
SOX5 SOX5 P35711 Transcription factor SOX-5 chr12 Not Cancer Driver No 1 intact, hippie 182 665 162 162 0
SOX6_ENST00000528429 SOX6 P35712 Transcription factor SOX-6 chr11 Not Cancer Driver No 1 intact, hippie 130 744 118 118 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 intact, hippie 96 599 71 71 0
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 intact, hippie 63 332 44 44 0
SPATA5 SPATA5 Q8NB90 ATPase family protein 2 homolog chr4 Not Cancer Driver No 1 hippie 101 165 16 16 10
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 73 252 38 38 1
SPTLC1 SPTLC1 O15269 Serine palmitoyltransferase 1 chr9 Not Cancer Driver No 1 hippie 50 27 5 5 5
SPTLC2 SPTLC2 O15270 Serine palmitoyltransferase 2 chr14 Not Cancer Driver No 1 hippie 72 9 2 2 5
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
SRGAP2 SRGAP2 O75044 SLIT-ROBO Rho GTPase-activating protein 2 chr1 Not Cancer Driver No 1 hippie 122 541 71 71 0
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie 27 0 0 0 6
SSR1 SSR1 P43307 Translocon-associated protein subunit alpha chr6 Not Cancer Driver No 1 hippie, biogrid 26 114 10 10 0
STARD9 STARD9 Q9P2P6 StAR-related lipid transfer protein 9 chr15 Not Cancer Driver No 1 hippie 104 3390 76 76 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STK25 STK25 O00506 Serine/threonine-protein kinase 25 chr2 Not Cancer Driver No 1 hippie 42 170 15 15 0
STK26 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX Not Cancer Driver No 1 hippie 62 119 18 18 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 Not Cancer Driver No 1 hippie 70 241 32 32 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 1 hippie 70 231 30 30 0
SURF1 SURF1 Q15526 Surfeit locus protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 17 82 6 6 11
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 1 hippie 83 483 46 46 3
TECR TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 Not Cancer Driver No 1 intact, hippie 41 0 0 0 1
TFAM TFAM Q00059 Transcription factor A, mitochondrial chr10 Not Cancer Driver No 1 hippie 25 110 15 15 1
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 68 169 23 23 0
TLX2 TLX2 O43763 T-cell leukemia homeobox protein 2 chr2 Not Cancer Driver No 1 intact, hippie 24 220 15 15 0
TLX3 TLX3 O43711 T-cell leukemia homeobox protein 3 chr5 Census Yes 1 intact, hippie 40 179 24 24 0
TMEM126A TMEM126A Q9H061 Transmembrane protein 126A chr11 Not Cancer Driver No 1 intact, hippie 18 7 1 1 0
TMEM223 TMEM223 A0PJW6 Transmembrane protein 223 chr11 Not Cancer Driver No 1 intact, hippie 19 6 0 0 0
TMEM70 TMEM70 Q9BUB7 Transmembrane protein 70, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 26 24 4 4 1
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie 78 412 52 52 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 1 intact, hippie 58 111 15 15 12
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 Not Cancer Driver No 1 intact, hippie 48 229 28 28 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TOP3B_ENST00000357179 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 Not Cancer Driver No 1 hippie, biogrid 102 151 17 17 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 intact, hippie 2891 282 1466 1466 83
TRADD TRADD Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein chr16 Not Cancer Driver No 1 intact, hippie 26 74 5 5 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 74 110 11 11 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 Not Cancer Driver No 1 intact, hippie 37 73 7 7 0
TSFM_ENST00000454289 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 37 74 7 7 2
TUBA1C_ENST00000301072 TUBA1C Q9BQE3 Tubulin alpha-1C chain chr12 Not Cancer Driver No 1 intact, hippie 39 50 5 5 0
TUBGCP2_ENST00000368563 TUBGCP2 Q9BSJ2 Gamma-tubulin complex component 2 chr10 Not Cancer Driver No 1 hippie 124 93 16 16 0
TUFM TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 2 intact, hippie, biogrid 51 50 3 3 1
TXNIP TXNIP Q9H3M7 Thioredoxin-interacting protein chr1 Not Cancer Driver No 1 hippie 61 77 14 14 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX Compendium Yes 1 hippie 35 67 13 13 2
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
UNC93B1 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 Not Cancer Driver No 1 intact, hippie 57 127 5 5 0
UQCRC2 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 53 48 13 13 1
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 59 86 6 6 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 188 110 28 28 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie, biogrid 88 186 16 16 16
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 38 36 4 4 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
WWC1_ENST00000265293 WWC1 Q8IX03 Protein KIBRA chr5 Not Cancer Driver No 1 hippie 147 550 81 81 0
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 79 108 9 9 3
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
YME1L1 YME1L1 Q96TA2 ATP-dependent zinc metalloprotease YME1L1 chr10 Not Cancer Driver No 1 intact, hippie 112 136 14 14 1
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0
ZFYVE21_ENST00000311141 ZFYVE21 Q9BQ24 Zinc finger FYVE domain-containing protein 21 chr14 Not Cancer Driver No 1 hippie 28 19 0 0 0
ZNF746_ENST00000340622 ZNF746 Q6NUN9 Zinc finger protein 746 chr7 Not Cancer Driver No 1 hippie 93 436 56 56 0