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ASS1_ENST00000352480 ,ASS1 ,P00966
  • Uniprot Accession= P00966
  • Ensembl Transcript= ENST00000352480.9
  • Uniprot Name= ASS1
  • Name= Argininosuccinate synthase
  • Chromosome= chr9
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 65
  • Number of Interaction partner in hippie: 132
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ACOX1_ENST00000301608 ACOX1 Q15067 Peroxisomal acyl-coenzyme A oxidase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 71 63 11 11 7
ADK ADK P55263 Adenosine kinase chr10 Not Cancer Driver No 1 hippie, biogrid 29 33 2 2 3
AKTIP_ENST00000570004 AKTIP Q9H8T0 AKT-interacting protein chr16 Not Cancer Driver No 1 hippie, biogrid 33 95 10 10 0
ALDOA_ENST00000643777 ALDOA P04075 Fructose-bisphosphate aldolase A chr16 Not Cancer Driver No 1 hippie, biogrid 47 65 9 9 3
ANXA11 ANXA11 P50995 Annexin A11 chr10 Not Cancer Driver No 1 hippie, biogrid 63 244 31 31 1
APOO APOO Q9BUR5 MICOS complex subunit MIC26 chrX Not Cancer Driver No 1 hippie, biogrid 25 23 4 4 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 hippie 84 181 32 32 0
ARHGDIA_ENST00000580685 ARHGDIA P52565 Rho GDP-dissociation inhibitor 1 chr17 Not Cancer Driver No 1 hippie, biogrid 25 50 6 6 0
ARMC12_ENST00000373866 ARMC12 Q5T9G4 Armadillo repeat-containing protein 12 chr6 Not Cancer Driver No 1 hippie 58 8 0 0 0
ASB18 ASB18 Q6ZVZ8 Ankyrin repeat and SOCS box protein 18 chr2 Not Cancer Driver No 1 hippie 37 82 0 0 0
ASB9 ASB9 Q96DX5 Ankyrin repeat and SOCS box protein 9 chrX Not Cancer Driver No 1 hippie 55 71 20 20 0
ASCC2 ASCC2 Q9H1I8 Activating signal cointegrator 1 complex subunit 2 chr22 Not Cancer Driver No 1 hippie, biogrid 87 326 34 34 0
ASNS_ENST00000394308 ASNS P08243 Asparagine synthetase [glutamine-hydrolyzing] chr7 Not Cancer Driver No 1 hippie, biogrid 81 11 0 0 3
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 Not Cancer Driver No 1 hippie 65 63 8 8 86
ATG3 ATG3 Q9NT62 Ubiquitin-like-conjugating enzyme ATG3 chr3 Not Cancer Driver No 1 hippie 29 110 9 9 0
ATP6V0A4 ATP6V0A4 Q9HBG4 V-type proton ATPase 116 kDa subunit a 4 chr7 Not Cancer Driver No 1 hippie, biogrid 148 43 6 6 6
B3GNT2 B3GNT2 Q9NY97 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 chr2 Not Cancer Driver No 1 hippie, biogrid 51 22 6 6 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 171 425 68 68 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BTBD1 BTBD1 Q9H0C5 BTB/POZ domain-containing protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 48 50 1 1 0
CA10_ENST00000285273 CA10 Q9NS85 Carbonic anhydrase-related protein 10 chr17 Not Cancer Driver No 3 hippie, biogrid 103 9 1 1 0
CAPN1_ENST00000533129 CAPN1 P07384 Calpain-1 catalytic subunit chr11 Not Cancer Driver No 1 hippie 68 32 2 2 1
CDR2 CDR2 Q01850 Cerebellar degeneration-related protein 2 chr16 Not Cancer Driver No 1 hippie 50 287 26 26 0
CENPK_ENST00000514814 CENPK Q9BS16 Centromere protein K chr5 Not Cancer Driver No 1 hippie, biogrid 28 91 8 8 0
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CNDP2_ENST00000579847 CNDP2 Q96KP4 Cytosolic non-specific dipeptidase chr18 Not Cancer Driver No 1 hippie 67 39 5 5 0
CTSA_ENST00000372459 CTSA P10619 Lysosomal protective protein chr20 Not Cancer Driver No 1 hippie 59 14 1 1 12
DAZAP1 DAZAP1 Q96EP5 DAZ-associated protein 1 chr19 Compendium Yes 1 hippie, biogrid 53 327 45 45 0
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie 67 17 0 0 10
DOLPP1 DOLPP1 Q86YN1 Dolichyldiphosphatase 1 chr9 Not Cancer Driver No 1 hippie, biogrid 21 2 0 0 0
DPP3 DPP3 Q9NY33 Dipeptidyl peptidase 3 chr11 Not Cancer Driver No 1 hippie 96 64 11 11 0
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 Not Cancer Driver No 1 hippie 26 54 6 6 0
ELN ELN P15502 Elastin chr7 Census, Compendium Yes 1 hippie 125 107 14 14 0
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 107 59 6 6 2
EMC4 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 1 hippie 15 17 2 2 0
EOGT EOGT Q5NDL2 EGF domain-specific O-linked N-acetylglucosamine transferase chr3 Not Cancer Driver No 1 hippie, biogrid 60 18 4 4 2
EPHX1_ENST00000366837 EPHX1 P07099 Epoxide hydrolase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 75 7 3 3 0
FAM117B FAM117B Q6P1L5 Protein FAM117B chr2 Not Cancer Driver No 1 hippie, biogrid 61 547 55 55 0
FAM20C FAM20C Q8IXL6 Extracellular serine/threonine protein kinase FAM20C chr7 Not Cancer Driver No 1 hippie 33 188 3 3 9
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FH FH P07954 Fumarate hydratase, mitochondrial chr1 Census, Compendium Yes 1 hippie, biogrid 67 76 5 5 13
FSCN1 FSCN1 Q16658 Fascin chr7 Not Cancer Driver No 1 hippie, biogrid 58 81 5 5 0
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 hippie, biogrid 39 24 3 3 0
GBP2 GBP2 P32456 Guanylate-binding protein 2 chr1 Not Cancer Driver No 1 hippie 75 134 15 15 0
GDF15 GDF15 Q99988 Growth/differentiation factor 15 chr19 Not Cancer Driver No 1 hippie, biogrid 39 143 20 20 0
GIT2 GIT2 Q14161 ARF GTPase-activating protein GIT2 chr12 Not Cancer Driver No 1 hippie, biogrid 83 492 47 47 0
GNPDA1_ENST00000311337 GNPDA1 P46926 Glucosamine-6-phosphate isomerase 1 chr5 Not Cancer Driver No 1 hippie, biogrid 23 17 3 3 0
GSR GSR P00390 Glutathione reductase, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 53 55 5 5 1
GSS_ENST00000216951 GSS P48637 Glutathione synthetase chr20 Not Cancer Driver No 1 hippie 61 49 6 6 14
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie 67 283 26 26 2
HSPH1_ENST00000320027 HSPH1 Q92598 Heat shock protein 105 kDa chr13 Not Cancer Driver No 1 hippie, biogrid 103 323 42 42 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 Compendium Yes 1 hippie, biogrid 44 127 9 9 2
ICAM4_ENST00000380770 ICAM4 Q14773 Intercellular adhesion molecule 4 chr19 Not Cancer Driver No 1 hippie, biogrid 34 40 3 3 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 Census, Compendium Yes 1 hippie 136 59 5 5 5
KPNA2_ENST00000330459 KPNA2 P52292 Importin subunit alpha-1 chr17 Not Cancer Driver No 1 hippie, biogrid 74 129 18 18 0
KYNU_ENST00000409512 KYNU Q16719 Kynureninase chr2 Not Cancer Driver No 1 hippie, biogrid 103 20 5 5 1
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 Census, Compendium Yes 1 hippie, biogrid 161 788 100 100 0
LDHB_ENST00000350669 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie, biogrid 47 15 2 2 11
LGI2 LGI2 Q8N0V4 Leucine-rich repeat LGI family member 2 chr4 Not Cancer Driver No 1 hippie, biogrid 96 0 0 0 0
LRRC49_ENST00000260382 LRRC49 Q8IUZ0 Leucine-rich repeat-containing protein 49 chr15 Not Cancer Driver No 1 hippie, biogrid 117 124 21 21 0
MBD2 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 Not Cancer Driver No 1 intact 26 384 25 25 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 Census Yes 1 hippie 92 208 22 22 85
MMGT1 MMGT1 Q8N4V1 ER membrane protein complex subunit 5 chrX Not Cancer Driver No 1 hippie 24 17 4 4 0
MPC1 MPC1 Q9Y5U8 Mitochondrial pyruvate carrier 1 chr6 Not Cancer Driver No 1 hippie, biogrid 8 0 0 0 2
MT2A MT2A P02795 Metallothionein-2 chr16 Not Cancer Driver No 1 hippie 8 0 0 0 0
MTAP MTAP Q13126 S-methyl-5'-thioadenosine phosphorylase chr9 Not Cancer Driver No 1 hippie, biogrid 37 15 0 0 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie 45 11 0 0 0
MVD MVD P53602 Diphosphomevalonate decarboxylase chr16 Not Cancer Driver No 1 hippie 47 49 10 10 3
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NAMPT NAMPT P43490 Nicotinamide phosphoribosyltransferase chr7 Not Cancer Driver No 1 hippie 50 27 5 5 0
NANS NANS Q9NR45 Sialic acid synthase chr9 Not Cancer Driver No 2 hippie, biogrid 29 45 1 1 6
NEUROG1 NEUROG1 Q92886 Neurogenin-1 chr5 Not Cancer Driver No 1 hippie, biogrid 27 178 18 18 0
NEUROG3 NEUROG3 Q9Y4Z2 Neurogenin-3 chr10 Not Cancer Driver No 1 hippie, biogrid 53 156 34 34 2
NHLRC2 NHLRC2 Q8NBF2 NHL repeat-containing protein 2 chr10 Not Cancer Driver No 1 hippie 74 103 12 12 0
NMRAL1 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 39 14 3 3 0
OAZ3_ENST00000639906 OAZ3 Q9UMX2 Ornithine decarboxylase antizyme 3 chr1 Not Cancer Driver No 1 hippie, biogrid 37 33 2 2 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 58 470 51 51 6
PABPN1L PABPN1L A6NDY0 Embryonic polyadenylate-binding protein 2 chr16 Not Cancer Driver No 1 hippie, biogrid 20 211 13 13 0
PAICS_ENST00000512576 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 Not Cancer Driver No 1 hippie, biogrid 23 35 3 3 0
PC PC P11498 Pyruvate carboxylase, mitochondrial chr11 Not Cancer Driver No 2 hippie, biogrid 185 172 27 27 9
PDCD6IP_ENST00000307296 PDCD6IP Q8WUM4 Programmed cell death 6-interacting protein chr3 Not Cancer Driver No 1 hippie, biogrid 85 272 22 22 0
PEPD PEPD P12955 Xaa-Pro dipeptidase chr19 Not Cancer Driver No 1 hippie 53 17 2 2 4
PFKL PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 Not Cancer Driver No 1 hippie, biogrid 91 29 4 4 0
PHGDH_ENST00000641023 PHGDH O43175 D-3-phosphoglycerate dehydrogenase chr1 Not Cancer Driver No 1 hippie, biogrid 51 38 4 4 8
PHIP PHIP Q8WWQ0 PH-interacting protein chr6 Not Cancer Driver No 1 hippie 239 835 110 110 0
PIR_ENST00000380420 PIR O00625 Pirin chrX Not Cancer Driver No 1 hippie, biogrid 29 185 16 16 0
PITRM1_ENST00000224949 PITRM1 Q5JRX3 Presequence protease, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 122 220 26 26 2
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie, biogrid 78 58 13 13 0
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 Not Cancer Driver No 1 hippie, biogrid 22 40 5 5 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 Not Cancer Driver No 1 hippie, biogrid 24 30 4 4 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 Not Cancer Driver No 1 hippie, biogrid 46 13 4 4 0
PRMT7_ENST00000441236 PRMT7 Q9NVM4 Protein arginine N-methyltransferase 7 chr16 Not Cancer Driver No 1 hippie 71 39 1 1 3
PTGR1_ENST00000309195 PTGR1 Q14914 Prostaglandin reductase 1 chr9 Not Cancer Driver No 1 hippie, biogrid 40 12 1 1 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie 49 140 25 25 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie 22 58 4 4 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RPGRIP1L_ENST00000379925 RPGRIP1L Q68CZ1 Protein fantom chr16 Not Cancer Driver No 1 hippie 177 586 94 94 8
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 Not Cancer Driver No 1 hippie 14 29 4 4 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 1 hippie, biogrid 62 100 13 13 0
SCLT1 SCLT1 Q96NL6 Sodium channel and clathrin linker 1 chr4 Not Cancer Driver No 1 hippie 98 398 61 61 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 Not Cancer Driver No 1 hippie, biogrid 78 7 2 2 0
SGTB SGTB Q96EQ0 Small glutamine-rich tetratricopeptide repeat-containing protein beta chr5 Not Cancer Driver No 1 hippie 28 114 10 10 0
SIRT3 SIRT3 Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial chr11 Not Cancer Driver No 2 hippie, biogrid 33 60 2 2 0
SLC13A1 SLC13A1 Q9BZW2 Solute carrier family 13 member 1 chr7 Not Cancer Driver No 1 hippie 146 39 6 6 0
SLC25A1 SLC25A1 P53007 Tricarboxylate transport protein, mitochondrial chr22 Not Cancer Driver No 1 hippie 22 34 2 2 17
SMARCA2 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 Not Cancer Driver No 1 hippie 273 1009 160 160 42
SORT1 SORT1 Q99523 Sortilin chr1 Not Cancer Driver No 1 hippie 69 110 2 2 0
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 Not Cancer Driver No 1 hippie 136 680 101 101 0
SPR SPR P35270 Sepiapterin reductase chr2 Not Cancer Driver No 1 hippie, biogrid 23 19 4 4 2
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 74 270 39 39 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TAGLN2_ENST00000368097 TAGLN2 P37802 Transgelin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 28 83 12 12 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 Not Cancer Driver No 1 hippie 63 220 34 34 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 Not Cancer Driver No 1 hippie 33 361 20 20 0
TKT_ENST00000462138 TKT P29401 Transketolase chr3 Not Cancer Driver No 1 hippie, biogrid 66 86 7 7 1
TMEM184A TMEM184A Q6ZMB5 Transmembrane protein 184A chr7 Not Cancer Driver No 2 hippie, biogrid 59 76 17 17 0
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie 78 412 52 52 0
TNFAIP8_ENST00000504771 TNFAIP8 O95379 Tumor necrosis factor alpha-induced protein 8 chr5 Not Cancer Driver No 1 hippie 21 13 1 1 0
TPI1_ENST00000396705 TPI1 P60174 Triosephosphate isomerase chr12 Not Cancer Driver No 1 hippie, biogrid 40 15 2 2 7
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM33 TRIM33 Q9UPN9 E3 ubiquitin-protein ligase TRIM33 chr1 Census, Compendium Yes 1 hippie 110 617 51 51 0
TXN TXN P10599 Thioredoxin chr9 Not Cancer Driver No 1 hippie, biogrid 6 0 0 0 0
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 Not Cancer Driver No 1 hippie 52 271 44 44 0
USP4 USP4 Q13107 Ubiquitin carboxyl-terminal hydrolase 4 chr3 Not Cancer Driver No 1 hippie 102 286 22 22 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 hippie 30 81 10 10 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0
ZNF354C ZNF354C Q86Y25 Zinc finger protein 354C chr5 Not Cancer Driver No 2 hippie, biogrid 109 77 30 30 0