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ARSA ,ARSA ,P15289
  • Uniprot Accession= P15289
  • Ensembl Transcript= ENST00000216124.9
  • Uniprot Name= ARSA
  • Name= Arylsulfatase A
  • Chromosome= chr22
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 23
  • Number of Interaction partner in biogrid: 50
  • Number of Interaction partner in hippie: 74
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADAMTS12 ADAMTS12 P58397 A disintegrin and metalloproteinase with thrombospondin motifs 12 chr5 Not Cancer Driver No 1 hippie, biogrid 504 374 128 128 0
ANXA11 ANXA11 P50995 Annexin A11 chr10 Not Cancer Driver No 1 hippie 63 244 31 31 1
ARSA ARSA P15289 Arylsulfatase A chr22 Not Cancer Driver No 1 hippie 46 61 7 7 97
ART5_ENST00000359918 ART5 Q96L15 Ecto-ADP-ribosyltransferase 5 chr11 Not Cancer Driver No 1 hippie, biogrid 42 21 3 3 0
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 Compendium Yes 1 hippie 141 601 70 70 19
C22orf39_ENST00000611555 C22orf39 Q6P5X5 UPF0545 protein C22orf39 chr22 Not Cancer Driver No 1 intact, hippie 8 47 4 4 0
CALR CALR P27797 Calreticulin chr19 Census Yes 1 hippie, biogrid 45 245 31 31 0
CAMK2B CAMK2B Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta chr7 Not Cancer Driver No 1 intact, hippie 86 273 28 28 6
CCDC22 CCDC22 O60826 Coiled-coil domain-containing protein 22 chrX Not Cancer Driver No 1 intact, hippie 62 243 18 18 2
CDC45_ENST00000407835 CDC45 O75419 Cell division control protein 45 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 73 66 16 16 5
CETN2 CETN2 P41208 Centrin-2 chrX Not Cancer Driver No 1 intact, hippie 33 97 11 11 0
CLEC4G CLEC4G Q6UXB4 C-type lectin domain family 4 member G chr19 Not Cancer Driver No 1 intact, hippie 40 35 4 4 0
CLGN_ENST00000414773 CLGN O14967 Calmegin chr4 Not Cancer Driver No 1 hippie, biogrid 86 255 36 36 0
CNPY3 CNPY3 Q9BT09 Protein canopy homolog 3 chr6 Not Cancer Driver No 1 hippie, biogrid 28 87 12 12 0
CNTNAP3 CNTNAP3 Q9BZ76 Contactin-associated protein-like 3 chr9 Not Cancer Driver No 1 hippie, biogrid 181 216 14 14 0
CTSL CTSL P07711 Procathepsin L chr9 Not Cancer Driver No 1 hippie 47 34 4 4 0
CTU1 CTU1 Q7Z7A3 Cytoplasmic tRNA 2-thiolation protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 12 60 1 1 0
DEFB135 DEFB135 Q30KP9 Beta-defensin 135 chr8 Not Cancer Driver No 1 hippie, biogrid 11 0 0 0 0
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 Not Cancer Driver No 1 hippie, biogrid 60 131 17 17 0
DNASE2B DNASE2B Q8WZ79 Deoxyribonuclease-2-beta chr1 Not Cancer Driver No 2 hippie, biogrid 53 14 1 1 0
DPEP2_ENST00000393847 DPEP2 Q9H4A9 Dipeptidase 2 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 66 73 4 4 0
EDN3_ENST00000371028 EDN3 P14138 Endothelin-3 chr20 Not Cancer Driver No 1 hippie, biogrid 69 140 44 44 3
EID2B EID2B Q96D98 EP300-interacting inhibitor of differentiation 2B chr19 Not Cancer Driver No 1 hippie 9 90 2 2 0
EID3 EID3 Q8N140 EP300-interacting inhibitor of differentiation 3 chr12 Not Cancer Driver No 1 intact 40 55 6 6 0
ENKD1 ENKD1 Q9H0I2 Enkurin domain-containing protein 1 chr16 Not Cancer Driver No 1 intact, hippie 40 307 34 34 0
ERFE ERFE Q4G0M1 Erythroferrone chr2 Not Cancer Driver No 1 hippie 4 179 0 0 0
FBXL12 FBXL12 Q9NXK8 F-box/LRR-repeat protein 12 chr19 Not Cancer Driver No 1 hippie, biogrid 41 0 0 0 0
FBXO21 FBXO21 O94952 F-box only protein 21 chr12 Not Cancer Driver No 1 hippie, biogrid 73 17 3 3 0
FOXI1 FOXI1 Q12951 Forkhead box protein I1 chr5 Not Cancer Driver No 1 intact, hippie 91 253 66 66 0
GAL3ST1 GAL3ST1 Q99999 Galactosylceramide sulfotransferase chr22 Not Cancer Driver No 1 hippie 103 15 2 2 0
GALNS GALNS P34059 N-acetylgalactosamine-6-sulfatase chr16 Not Cancer Driver No 3 hippie, biogrid 65 37 3 3 126
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 Not Cancer Driver No 1 hippie, biogrid 82 42 6 6 0
GFPT2 GFPT2 O94808 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 chr5 Not Cancer Driver No 1 hippie, biogrid 121 42 8 8 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 intact, hippie 36 25 6 6 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie, biogrid 94 268 35 35 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie, biogrid 73 282 35 35 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 61 82 6 6 2
INSL5 INSL5 Q9Y5Q6 Insulin-like peptide INSL5 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 27 56 7 7 0
KLK5_ENST00000593428 KLK5 Q9Y337 Kallikrein-5 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 69 75 16 16 0
LRPAP1 LRPAP1 P30533 Alpha-2-macroglobulin receptor-associated protein chr4 Not Cancer Driver No 1 hippie, biogrid 41 188 20 20 0
MANF MANF P55145 Mesencephalic astrocyte-derived neurotrophic factor chr3 Not Cancer Driver No 1 hippie, biogrid 14 1 0 0 0
MESD_ENST00000561312 MESD Q14696 LRP chaperone MESD chr15 Not Cancer Driver No 2 intact, hippie 21 150 14 14 0
NAAA NAAA Q02083 N-acylethanolamine-hydrolyzing acid amidase chr4 Not Cancer Driver No 1 hippie, biogrid 42 43 3 3 0
NCR3 NCR3 O14931 Natural cytotoxicity triggering receptor 3 chr6 Not Cancer Driver No 1 hippie, biogrid 26 31 2 2 0
NDUFV3_ENST00000340344 NDUFV3 P56181 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial chr21 Not Cancer Driver No 1 hippie, biogrid 5 95 4 4 0
NFXL1 NFXL1 Q6ZNB6 NF-X1-type zinc finger protein NFXL1 chr4 Not Cancer Driver No 1 hippie, biogrid 102 183 15 15 0
NT5C1A NT5C1A Q9BXI3 Cytosolic 5'-nucleotidase 1A chr1 Not Cancer Driver No 1 hippie, biogrid 86 95 16 16 0
NXPH4 NXPH4 O95158 Neurexophilin-4 chr12 Not Cancer Driver No 1 hippie, biogrid 26 42 0 0 0
PDIA4 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie, biogrid 81 147 22 22 0
PDIA5 PDIA5 Q14554 Protein disulfide-isomerase A5 chr3 Not Cancer Driver No 2 hippie, biogrid 73 79 9 9 0
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 Not Cancer Driver No 1 intact, hippie 120 459 54 54 0
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 Not Cancer Driver No 3 hippie, biogrid 49 18 5 5 0
PLD4_ENST00000392593 PLD4 Q96BZ4 5'-3' exonuclease PLD4 chr14 Not Cancer Driver No 1 biogrid 46 76 10 10 0
POU1F1_ENST00000350375 POU1F1 P28069 Pituitary-specific positive transcription factor 1 chr3 Not Cancer Driver No 1 intact, hippie 45 81 16 16 13
PPIC PPIC P45877 Peptidyl-prolyl cis-trans isomerase C chr5 Not Cancer Driver No 1 hippie 24 1 1 1 0
PPOX PPOX P50336 Protoporphyrinogen oxidase chr1 Not Cancer Driver No 1 hippie, biogrid 48 34 6 6 56
PROP1 PROP1 O75360 Homeobox protein prophet of Pit-1 chr5 Not Cancer Driver No 1 intact, hippie 35 194 32 32 7
PTPRK_ENST00000368215 PTPRK Q15262 Receptor-type tyrosine-protein phosphatase kappa chr6 Census, Compendium Yes 3 intact, hippie, biogrid 292 302 57 57 0
RAB25 RAB25 P57735 Ras-related protein Rab-25 chr1 Not Cancer Driver No 1 hippie, biogrid 26 32 5 5 0
RHOXF2 RHOXF2 Q9BQY4 Rhox homeobox family member 2 chrX Not Cancer Driver No 1 intact, hippie 32 156 23 23 0
SCGB1D1 SCGB1D1 O95968 Secretoglobin family 1D member 1 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 22 0 0 0 0
SEMA3B_ENST00000616701 SEMA3B Q13214 Semaphorin-3B chr3 Not Cancer Driver No 1 hippie, biogrid 46 145 8 8 0
SGSH SGSH P51688 N-sulphoglucosamine sulphohydrolase chr17 Not Cancer Driver No 1 hippie, biogrid 45 44 2 2 56
SH2D3A SH2D3A Q9BRG2 SH2 domain-containing protein 3A chr19 Not Cancer Driver No 1 hippie, biogrid 68 305 40 40 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 Not Cancer Driver No 1 hippie 21 107 13 13 5
SUMF1 SUMF1 Q8NBK3 Formylglycine-generating enzyme chr3 Not Cancer Driver No 3 hippie, biogrid 41 141 15 15 16
SUSD4 SUSD4 Q5VX71 Sushi domain-containing protein 4 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 85 134 27 27 0
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 Not Cancer Driver No 1 hippie 77 275 44 44 4
TMEM25_ENST00000313236 TMEM25 Q86YD3 Transmembrane protein 25 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 50 128 11 11 0
TNFRSF6B TNFRSF6B O95407 Tumor necrosis factor receptor superfamily member 6B chr20 Not Cancer Driver No 1 hippie, biogrid 22 22 3 3 0
TRIP13 TRIP13 Q15645 Pachytene checkpoint protein 2 homolog chr5 Not Cancer Driver No 5 intact, hippie 62 30 6 6 1
TUBB8 TUBB8 Q3ZCM7 Tubulin beta-8 chain chr10 Not Cancer Driver No 1 hippie, biogrid 103 53 18 18 13
UPK1A_ENST00000222275 UPK1A O00322 Uroplakin-1a chr19 Not Cancer Driver No 1 hippie, biogrid 36 0 0 0 0
VENTX VENTX O95231 Homeobox protein VENTX chr10 Not Cancer Driver No 1 intact, hippie 45 198 31 31 0
WNT16 WNT16 Q9UBV4 Protein Wnt-16 chr7 Not Cancer Driver No 1 hippie, biogrid 59 28 9 9 0
ZBTB43_ENST00000449886 ZBTB43 O43298 Zinc finger and BTB domain-containing protein 43 chr9 Not Cancer Driver No 3 hippie, biogrid 56 252 33 33 0