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ARPC5_ENST00000359856 ,ARPC5 ,O15511
  • Uniprot Accession= O15511
  • Ensembl Transcript= ENST00000359856.10
  • Uniprot Name= ARPC5
  • Name= Actin-related protein 2/3 complex subunit 5
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 31
  • Number of Interaction partner in biogrid: 30
  • Number of Interaction partner in hippie: 82
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AARSD1 AARSD1 Q9BTE6 Alanyl-tRNA editing protein Aarsd1 chr17 Not Cancer Driver No 1 hippie 40 157 20 20 0
ABCE1 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 Not Cancer Driver No 1 hippie 74 36 6 6 0
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 intact 70 48 14 14 84
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 Not Cancer Driver No 6 intact, hippie, biogrid 51 6 2 2 0
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 Not Cancer Driver No 8 intact, hippie, biogrid 32 16 2 2 0
ACTR3B ACTR3B Q9P1U1 Actin-related protein 3B chr7 Not Cancer Driver No 4 intact, hippie, biogrid 55 5 0 0 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 intact, hippie 144 767 104 104 2
ANP32B ANP32B Q92688 Acidic leucine-rich nuclear phosphoprotein 32 family member B chr9 Not Cancer Driver No 1 hippie 22 117 12 12 0
ARPC1A ARPC1A Q92747 Actin-related protein 2/3 complex subunit 1A chr7 Not Cancer Driver No 8 intact, hippie, biogrid 48 27 7 7 0
ARPC1B_ENST00000431816 ARPC1B O15143 Actin-related protein 2/3 complex subunit 1B chr7 Not Cancer Driver No 10 intact, hippie, biogrid 37 34 1 1 0
ARPC2_ENST00000315717 ARPC2 O15144 Actin-related protein 2/3 complex subunit 2 chr2 Not Cancer Driver No 5 intact, hippie, biogrid 40 49 8 8 0
ARPC3 ARPC3 O15145 Actin-related protein 2/3 complex subunit 3 chr12 Not Cancer Driver No 7 intact, hippie, biogrid 17 26 6 6 0
ARPC4-TTLL3 ARPC4-TTLL3 P59998-2 Isoform 2 of Actin-related protein 2/3 complex subunit 4 chr3 Not Cancer Driver No 1 biogrid 64 79 7 7 0
ARPC4_ENST00000397261 ARPC4 P59998 Actin-related protein 2/3 complex subunit 4 chr3 Not Cancer Driver No 6 intact, hippie, biogrid 11 3 0 0 0
ARPC5L ARPC5L Q9BPX5 Actin-related protein 2/3 complex subunit 5-like protein chr9 Not Cancer Driver No 2 hippie, biogrid 4 48 0 0 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 Not Cancer Driver No 1 hippie 49 154 13 13 0
ASCC3 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 279 87 8 8 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 115 546 73 73 10
BRD3 BRD3 Q15059 Bromodomain-containing protein 3 chr9 Census Yes 1 hippie 87 566 68 68 0
BTF3L4 BTF3L4 Q96K17 Transcription factor BTF3 homolog 4 chr1 Not Cancer Driver No 1 hippie 11 131 8 8 0
CALR CALR P27797 Calreticulin chr19 Census Yes 1 hippie 45 245 31 31 0
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 1 hippie 37 19 0 0 0
CAPZB_ENST00000375142 CAPZB P47756 F-actin-capping protein subunit beta chr1 Not Cancer Driver No 1 hippie, biogrid 33 66 3 3 0
CBWD3 CBWD3 Q5JTY5 COBW domain-containing protein 3 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 16 62 1 1 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 intact, hippie 39 23 2 2 1
CHURC1_ENST00000552002 CHURC1 Q8WUH1 Protein Churchill chr14 Not Cancer Driver No 1 hippie, biogrid 10 0 0 0 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 42 123 9 9 1
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 193 114 11 11 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 Not Cancer Driver No 1 intact, hippie 84 510 73 73 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 48 53 6 6 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EIF3H EIF3H O15372 Eukaryotic translation initiation factor 3 subunit H chr8 Not Cancer Driver No 1 hippie, biogrid 37 109 12 12 0
EIF4B_ENST00000262056 EIF4B P23588 Eukaryotic translation initiation factor 4B chr12 Not Cancer Driver No 1 hippie 94 589 90 90 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
GGACT GGACT Q9BVM4 Gamma-glutamylaminecyclotransferase chr13 Not Cancer Driver No 1 hippie, biogrid 4 51 0 0 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie 86 110 26 26 50
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HTRA4 HTRA4 P83105 Serine protease HTRA4 chr8 Not Cancer Driver No 1 hippie 57 15 0 0 0
HUS1 HUS1 O60921 Checkpoint protein HUS1 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 25 17 2 2 0
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 Not Cancer Driver No 1 hippie 43 92 5 5 0
METTL1 METTL1 Q9UBP6 tRNA (guanine-N(7)-)-methyltransferase chr12 Not Cancer Driver No 1 hippie 43 89 11 11 0
MKS1 MKS1 Q9NXB0 Meckel syndrome type 1 protein chr17 Not Cancer Driver No 2 intact, hippie, biogrid 82 152 23 23 2
MTPAP MTPAP Q9NVV4 Poly(A) RNA polymerase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 73 136 22 22 1
MYH11_ENST00000300036 MYH11 P35749 Myosin-11 chr16 Census, Compendium Yes 1 hippie 353 1180 201 201 2
MYO5C MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 intact, hippie 204 394 43 43 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 Not Cancer Driver No 1 intact, hippie 33 121 12 12 0
PKD2 PKD2 Q13563 Polycystin-2 chr4 Not Cancer Driver No 1 intact 113 375 35 35 10
POLA2 POLA2 Q14181 DNA polymerase alpha subunit B chr11 Not Cancer Driver No 2 hippie, biogrid 63 102 16 16 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 72 44 4 4 3
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 Not Cancer Driver No 1 hippie 72 17 1 1 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 Compendium Yes 2 hippie, biogrid 118 246 34 34 0
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 2 intact, hippie, biogrid 115 421 74 74 3
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 Compendium Yes 1 hippie 154 181 25 25 3
RBCK1 RBCK1 Q9BYM8 RanBP-type and C3HC4-type zinc finger-containing protein 1 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 52 140 14 14 2
RNASEH2B RNASEH2B Q5TBB1 Ribonuclease H2 subunit B chr13 Not Cancer Driver No 1 intact, hippie 34 84 9 9 14
RPA3 RPA3 P35244 Replication protein A 14 kDa subunit chr7 Not Cancer Driver No 1 hippie 13 4 1 1 0
SH3BGRL SH3BGRL O75368 SH3 domain-binding glutamic acid-rich-like protein chrX Not Cancer Driver No 1 intact, hippie 23 51 8 8 0
SH3GL1 SH3GL1 Q99961 Endophilin-A2 chr19 Census Yes 1 hippie 45 245 33 33 0
SIK2 SIK2 Q9H0K1 Serine/threonine-protein kinase SIK2 chr11 Not Cancer Driver No 1 hippie 94 525 56 56 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SYNPO SYNPO Q8N3V7 Synaptopodin chr5 Not Cancer Driver No 1 intact, hippie 103 918 102 102 0
TAX1BP1 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 Not Cancer Driver No 1 hippie 78 429 50 50 0
TCP11L1_ENST00000432887 TCP11L1 Q9NUJ3 T-complex protein 11-like protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 59 74 8 8 0
TOM1L1 TOM1L1 O75674 TOM1-like protein 1 chr17 Not Cancer Driver No 1 hippie 51 268 29 29 0
TPRKB_ENST00000272424 TPRKB Q9Y3C4 EKC/KEOPS complex subunit TPRKB chr2 Not Cancer Driver No 1 hippie 20 0 0 0 2
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRO TRO Q12816 Trophinin chrX Not Cancer Driver No 2 hippie, biogrid 220 593 81 81 0
TUBA4A TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 1 intact, hippie, biogrid 73 39 4 4 5
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 Not Cancer Driver No 1 intact, hippie, biogrid 20 102 8 8 0
VMP1 VMP1 Q96GC9 Vacuole membrane protein 1 chr17 Not Cancer Driver No 1 hippie 57 68 11 11 0
VPS13A VPS13A Q96RL7 Intermembrane lipid transfer protein VPS13A chr9 Not Cancer Driver No 2 hippie, biogrid 375 208 18 18 6
VPS13C_ENST00000261517 VPS13C Q709C8 Intermembrane lipid transfer protein VPS13C chr15 Not Cancer Driver No 2 intact, hippie, biogrid 446 433 51 51 1
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0
ZWINT ZWINT O95229 ZW10 interactor chr10 Not Cancer Driver No 1 hippie 65 168 44 44 0