Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADH5 | ADH5 | P11766 | Alcohol dehydrogenase class-3 | chr4 | Not Cancer Driver | No | 1 | hippie | 36 | 2 | 1 | 1 | 0 |
| ADSL | ADSL | P30566 | Adenylosuccinate lyase | chr22 | Not Cancer Driver | No | 1 | hippie | 68 | 36 | 9 | 9 | 27 |
| AHR | AHR | P35869 | Aryl hydrocarbon receptor | chr7 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 129 | 351 | 75 | 75 | 0 |
| AHRR_ENST00000505113 | AHRR | A9YTQ3 | Aryl hydrocarbon receptor repressor | chr5 | Not Cancer Driver | No | 1 | hippie | 117 | 462 | 66 | 66 | 0 |
| AIP | AIP | O00170 | AH receptor-interacting protein | chr11 | Not Cancer Driver | No | 1 | hippie | 32 | 64 | 9 | 9 | 1 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | Census, Compendium | Yes | 1 | hippie | 108 | 158 | 24 | 24 | 4 |
| ARL14 | ARL14 | Q8N4G2 | ADP-ribosylation factor-like protein 14 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 27 | 15 | 2 | 2 | 0 |
| ARNT | ARNT | P27540 | Aryl hydrocarbon receptor nuclear translocator | chr1 | Census | Yes | 2 | intact, hippie | 77 | 511 | 56 | 56 | 0 |
| ARNT2 | ARNT2 | Q9HBZ2 | Aryl hydrocarbon receptor nuclear translocator 2 | chr15 | Not Cancer Driver | No | 1 | hippie | 100 | 448 | 61 | 61 | 0 |
| ARPC2_ENST00000315717 | ARPC2 | O15144 | Actin-related protein 2/3 complex subunit 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 40 | 49 | 8 | 8 | 0 |
| ASF1A | ASF1A | Q9Y294 | Histone chaperone ASF1A | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 69 | 2 | 2 | 0 |
| BAG2 | BAG2 | O95816 | BAG family molecular chaperone regulator 2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 112 | 9 | 9 | 0 |
| BCAT1_ENST00000261192 | BCAT1 | P54687 | Branched-chain-amino-acid aminotransferase, cytosolic | chr12 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 67 | 8 | 2 | 2 | 0 |
| BECN1_ENST00000590099 | BECN1 | Q14457 | Beclin-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 45 | 190 | 19 | 19 | 0 |
| BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 224 | 1458 | 174 | 174 | 35 |
| C1QTNF2 | C1QTNF2 | A0A499FIM1 | C1q and tumor necrosis factor related protein 2 | chr5 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 58 | 169 | 38 | 38 | 0 |
| CAD | CAD | P27708 | CAD protein | chr2 | Not Cancer Driver | No | 1 | hippie | 287 | 368 | 52 | 52 | 1 |
| CALCOCO1 | CALCOCO1 | Q9P1Z2 | Calcium-binding and coiled-coil domain-containing protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 88 | 486 | 59 | 59 | 0 |
| CALM1 | CALM1 | P0DP23 | Calmodulin-1 | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 19 | 115 | 15 | 15 | 7 |
| CALML3 | CALML3 | P27482 | Calmodulin-like protein 3 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 105 | 28 | 28 | 0 |
| CAND1 | CAND1 | Q86VP6 | Cullin-associated NEDD8-dissociated protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 161 | 88 | 7 | 7 | 0 |
| CASP3 | CASP3 | P42574 | Caspase-3 | chr4 | Census | Yes | 1 | hippie | 32 | 62 | 5 | 5 | 0 |
| CASP9 | CASP9 | P55211 | Caspase-9 | chr1 | Census | Yes | 1 | hippie | 49 | 71 | 7 | 7 | 0 |
| CCND2 | CCND2 | P30279 | G1/S-specific cyclin-D2 | chr12 | Census, Compendium | Yes | 1 | hippie | 39 | 29 | 7 | 7 | 5 |
| CCNE1 | CCNE1 | P24864 | G1/S-specific cyclin-E1 | chr19 | Census | Yes | 1 | hippie | 63 | 142 | 26 | 26 | 0 |
| CD44 | CD44 | P16070 | CD44 antigen | chr11 | Not Cancer Driver | No | 1 | hippie | 75 | 542 | 60 | 60 | 0 |
| CDK4 | CDK4 | P11802 | Cyclin-dependent kinase 4 | chr12 | Census, Compendium | Yes | 1 | hippie | 52 | 52 | 5 | 5 | 3 |
| CDK6 | CDK6 | Q00534 | Cyclin-dependent kinase 6 | chr7 | Census | Yes | 1 | hippie | 40 | 24 | 3 | 3 | 1 |
| CDK9 | CDK9 | P50750 | Cyclin-dependent kinase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 50 | 34 | 2 | 2 | 0 |
| CDKN2A_ENST00000304494 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | Census, Compendium | Yes | 1 | hippie | 166 | 83 | 88 | 88 | 36 |
| CDKN2B | CDKN2B | P42772 | Cyclin-dependent kinase 4 inhibitor B | chr9 | Not Cancer Driver | No | 1 | hippie | 15 | 67 | 3 | 3 | 0 |
| CDKN2C_ENST00000371761 | CDKN2C | P42773 | Cyclin-dependent kinase 4 inhibitor C | chr1 | Census, Compendium | Yes | 1 | hippie | 23 | 49 | 6 | 6 | 0 |
| CHD4 | CHD4 | Q14839 | Chromodomain-helicase-DNA-binding protein 4 | chr12 | Census, Compendium | Yes | 1 | hippie | 419 | 974 | 177 | 177 | 6 |
| CIAO3 | CIAO3 | Q9H6Q4 | Cytosolic iron-sulfur assembly component 3 | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 49 | 68 | 4 | 4 | 0 |
| CIC | CIC | Q96RK0 | Protein capicua homolog | chr19 | Census, Compendium | Yes | 1 | hippie | 276 | 1550 | 266 | 266 | 0 |
| CNBP_ENST00000422453 | CNBP | P62633 | CCHC-type zinc finger nucleic acid binding protein | chr3 | Census | Yes | 1 | hippie | 11 | 19 | 0 | 0 | 0 |
| CREB1_ENST00000430624 | CREB1 | P16220 | Cyclic AMP-responsive element-binding protein 1 | chr2 | Census | Yes | 1 | intact, hippie | 25 | 277 | 23 | 23 | 0 |
| CSNK2A1_ENST00000400217 | CSNK2A1 | P68400 | Casein kinase II subunit alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 71 | 75 | 8 | 8 | 4 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | Census, Compendium | Yes | 1 | hippie | 415 | 288 | 301 | 301 | 14 |
| CTTN_ENST00000301843 | CTTN | Q14247 | Src substrate cortactin | chr11 | Not Cancer Driver | No | 1 | hippie | 78 | 465 | 56 | 56 | 0 |
| CUL2_ENST00000374748 | CUL2 | Q13617 | Cullin-2 | chr10 | Not Cancer Driver | No | 2 | hippie, biogrid | 87 | 66 | 3 | 3 | 0 |
| CUL4A | CUL4A | Q13619 | Cullin-4A | chr13 | Not Cancer Driver | No | 1 | hippie | 64 | 102 | 2 | 2 | 0 |
| CYP1B1 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | Not Cancer Driver | No | 1 | hippie | 61 | 31 | 3 | 3 | 40 |
| DCAF15 | DCAF15 | Q66K64 | DDB1- and CUL4-associated factor 15 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 50 | 173 | 18 | 18 | 0 |
| DIABLO | DIABLO | Q9NR28 | Diablo IAP-binding mitochondrial protein | chr12 | Not Cancer Driver | No | 1 | hippie | 62 | 54 | 8 | 8 | 1 |
| DNAJA2 | DNAJA2 | O60884 | DnaJ homolog subfamily A member 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 50 | 174 | 27 | 27 | 0 |
| DNM2_ENST00000355667 | DNM2 | P50570 | Dynamin-2 | chr19 | Census | Yes | 1 | hippie | 138 | 270 | 43 | 43 | 22 |
| DPM1_ENST00000371588 | DPM1 | O60762 | Dolichol-phosphate mannosyltransferase subunit 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 38 | 29 | 6 | 6 | 3 |
| EGLN1 | EGLN1 | Q9GZT9 | Egl nine homolog 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 35 | 206 | 8 | 8 | 2 |
| EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
| ELAVL1 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 69 | 43 | 5 | 5 | 0 |
| ELOB_ENST00000409906 | ELOB | Q15370 | Elongin-B | chr16 | Not Cancer Driver | No | 1 | hippie | 13 | 69 | 10 | 10 | 0 |
| ELOC | ELOC | Q15369 | Elongin-C | chr8 | Not Cancer Driver | No | 1 | hippie | 22 | 25 | 5 | 5 | 0 |
| EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 334 | 1790 | 196 | 196 | 1 |
| EPAS1 | EPAS1 | Q99814 | Endothelial PAS domain-containing protein 1 | chr2 | Census, Compendium | Yes | 5 | intact, hippie, biogrid | 120 | 449 | 53 | 53 | 6 |
| EPHA2 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | Compendium | Yes | 1 | hippie | 171 | 187 | 39 | 39 | 3 |
| ERBB2 | ERBB2 | P04626 | Receptor tyrosine-protein kinase erbB-2 | chr17 | Census, Compendium | Yes | 1 | hippie | 275 | 314 | 41 | 41 | 1 |
| ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
| ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
| FEM1A | FEM1A | Q9BSK4 | Protein fem-1 homolog A | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 162 | 22 | 22 | 0 |
| FEV | FEV | Q99581 | Protein FEV | chr2 | Census | Yes | 1 | hippie | 15 | 55 | 0 | 0 | 0 |
| FGFR4 | FGFR4 | P22455 | Fibroblast growth factor receptor 4 | chr5 | Census, Compendium | Yes | 1 | hippie | 113 | 162 | 28 | 28 | 0 |
| FLOT2 | FLOT2 | Q14254 | Flotillin-2 | chr17 | Not Cancer Driver | No | 1 | hippie | 56 | 20 | 3 | 3 | 0 |
| FOXN1 | FOXN1 | O15353 | Forkhead box protein N1 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 90 | 483 | 65 | 65 | 2 |
| FOXR2 | FOXR2 | Q6PJQ5 | Forkhead box protein R2 | chrX | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 79 | 128 | 41 | 41 | 0 |
| FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | Not Cancer Driver | No | 1 | hippie | 92 | 70 | 13 | 13 | 0 |
| FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 74 | 184 | 30 | 30 | 0 |
| GIP | GIP | P09681 | Gastric inhibitory polypeptide | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 68 | 16 | 16 | 0 |
| GLIS1 | GLIS1 | Q8NBF1 | Zinc finger protein GLIS1 | chr1 | Not Cancer Driver | No | 1 | hippie | 106 | 404 | 66 | 66 | 0 |
| GLIS2 | GLIS2 | Q9BZE0 | Zinc finger protein GLIS2 | chr16 | Not Cancer Driver | No | 1 | hippie | 42 | 300 | 25 | 25 | 0 |
| GMNN_ENST00000620958 | GMNN | O75496 | Geminin | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 24 | 206 | 24 | 24 | 1 |
| GNAI1 | GNAI1 | P63096 | Guanine nucleotide-binding protein G(i) subunit alpha-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 52 | 11 | 3 | 3 | 0 |
| GNAI2 | GNAI2 | P04899 | Guanine nucleotide-binding protein G(i) subunit alpha-2 | chr3 | Compendium | Yes | 1 | hippie | 50 | 24 | 0 | 0 | 0 |
| GNAS_ENST00000371075 | GNAS | O95467 | Neuroendocrine secretory protein 55 | chr20 | Census, Compendium | Yes | 1 | hippie | 71 | 221 | 65 | 65 | 0 |
| GTF2F1 | GTF2F1 | P35269 | General transcription factor IIF subunit 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 63 | 426 | 48 | 48 | 0 |
| GTF2F2 | GTF2F2 | P13984 | General transcription factor IIF subunit 2 | chr13 | Not Cancer Driver | No | 1 | hippie | 20 | 112 | 9 | 9 | 0 |
| HDAC1 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 47 | 135 | 10 | 10 | 0 |
| HERC2 | HERC2 | O95714 | E3 ubiquitin-protein ligase HERC2 | chr15 | Compendium | Yes | 1 | hippie | 718 | 971 | 150 | 150 | 1 |
| HEY1_ENST00000354724 | HEY1 | Q9Y5J3 | Hairy/enhancer-of-split related with YRPW motif protein 1 | chr8 | Census | Yes | 1 | hippie | 33 | 172 | 15 | 15 | 0 |
| HEY2 | HEY2 | Q9UBP5 | Hairy/enhancer-of-split related with YRPW motif protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 64 | 179 | 26 | 26 | 0 |
| HGF_ENST00000644543 | HGF | P14210 | Hepatocyte growth factor | chr7 | Compendium | Yes | 1 | hippie | 233 | 43 | 16 | 16 | 0 |
| HIF1AN | HIF1AN | Q9NWT6 | Hypoxia-inducible factor 1-alpha inhibitor | chr10 | Not Cancer Driver | No | 1 | hippie | 37 | 77 | 9 | 9 | 0 |
| HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | Census | Yes | 3 | hippie, biogrid | 118 | 435 | 51 | 51 | 0 |
| HIF3A | HIF3A | Q9Y2N7 | Hypoxia-inducible factor 3-alpha | chr19 | Not Cancer Driver | No | 1 | hippie | 146 | 361 | 94 | 94 | 0 |
| HK1_ENST00000359426 | HK1 | P19367 | Hexokinase-1 | chr10 | Not Cancer Driver | No | 1 | hippie | 127 | 75 | 16 | 16 | 6 |
| HMGB1_ENST00000405805 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | Not Cancer Driver | No | 1 | hippie | 25 | 203 | 20 | 20 | 0 |
| HNF4A | HNF4A | P41235 | Hepatocyte nuclear factor 4-alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 135 | 127 | 48 | 48 | 5 |
| HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | Census, Compendium | Yes | 1 | hippie | 106 | 257 | 37 | 37 | 0 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 24 | 200 | 13 | 13 | 0 |
| HSPA2_ENST00000247207 | HSPA2 | P54652 | Heat shock-related 70 kDa protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 93 | 286 | 38 | 38 | 0 |
| HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 149 | 251 | 52 | 52 | 0 |
| HSPA9 | HSPA9 | P38646 | Stress-70 protein, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie | 67 | 283 | 26 | 26 | 2 |
| HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 10 | 118 | 8 | 8 | 20 |
| HSPD1 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 61 | 82 | 6 | 6 | 2 |
| ICAM1 | ICAM1 | P05362 | Intercellular adhesion molecule 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 61 | 251 | 28 | 28 | 0 |
| IKBKG_ENST00000611071 | IKBKG | Q9Y6K9 | NF-kappa-B essential modulator | chrX | Not Cancer Driver | No | 1 | hippie | 6 | 301 | 6 | 6 | 22 |
| IRAK4_ENST00000551736 | IRAK4 | Q9NWZ3 | Interleukin-1 receptor-associated kinase 4 | chr12 | Not Cancer Driver | No | 1 | hippie | 68 | 116 | 20 | 20 | 2 |
| JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
| JUP | JUP | P14923 | Junction plakoglobin | chr17 | Not Cancer Driver | No | 1 | hippie | 112 | 241 | 37 | 37 | 0 |
| KLC1_ENST00000348520 | KLC1 | Q07866 | Kinesin light chain 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 54 | 292 | 31 | 31 | 0 |
| KPNA1 | KPNA1 | P52294 | Importin subunit alpha-5 | chr3 | Not Cancer Driver | No | 1 | hippie | 65 | 121 | 18 | 18 | 0 |
| KPNA3 | KPNA3 | O00505 | Importin subunit alpha-4 | chr13 | Not Cancer Driver | No | 1 | hippie | 65 | 108 | 11 | 11 | 0 |
| KPNA5 | KPNA5 | O15131 | Importin subunit alpha-6 | chr6 | Not Cancer Driver | No | 1 | hippie | 65 | 133 | 13 | 13 | 0 |
| KPNA6 | KPNA6 | O60684 | Importin subunit alpha-7 | chr1 | Not Cancer Driver | No | 1 | hippie | 70 | 97 | 17 | 17 | 0 |
| KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 1 | hippie | 788 | 7 | 2 | 2 | 27 |
| LATS2 | LATS2 | Q9NRM7 | Serine/threonine-protein kinase LATS2 | chr13 | Census, Compendium | Yes | 1 | hippie | 178 | 687 | 116 | 116 | 0 |
| LDHA_ENST00000422447 | LDHA | P00338 | L-lactate dehydrogenase A chain | chr11 | Not Cancer Driver | No | 1 | hippie | 40 | 9 | 0 | 0 | 0 |
| LOX | LOX | P28300 | Protein-lysine 6-oxidase | chr5 | Compendium | Yes | 1 | hippie, biogrid | 44 | 172 | 11 | 11 | 4 |
| LRRC59 | LRRC59 | Q96AG4 | Leucine-rich repeat-containing protein 59 | chr17 | Not Cancer Driver | No | 1 | hippie | 33 | 122 | 15 | 15 | 0 |
| LSM8 | LSM8 | O95777 | U6 snRNA-associated Sm-like protein LSm8 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 14 | 3 | 1 | 1 | 0 |
| LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | Census | Yes | 1 | hippie | 95 | 84 | 12 | 12 | 0 |
| MAD2L1 | MAD2L1 | Q13257 | Mitotic spindle assembly checkpoint protein MAD2A | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 12 | 1 | 1 | 0 |
| MAP2K3 | MAP2K3 | P46734 | Dual specificity mitogen-activated protein kinase kinase 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 104 | 75 | 27 | 27 | 0 |
| MAP2K5 | MAP2K5 | Q13163 | Dual specificity mitogen-activated protein kinase kinase 5 | chr15 | Not Cancer Driver | No | 1 | hippie | 40 | 85 | 10 | 10 | 0 |
| MAPK14_ENST00000229794 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | Not Cancer Driver | No | 1 | hippie | 39 | 25 | 1 | 1 | 0 |
| MATR3_ENST00000509990 | MATR3 | P43243 | Matrin-3 | chr5 | Not Cancer Driver | No | 1 | hippie | 98 | 611 | 68 | 68 | 3 |
| MPRIP_ENST00000341712 | MPRIP | Q6WCQ1 | Myosin phosphatase Rho-interacting protein | chr17 | Not Cancer Driver | No | 1 | hippie | 118 | 735 | 95 | 95 | 0 |
| MTA3 | MTA3 | Q9BTC8 | Metastasis-associated protein MTA3 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 48 | 169 | 18 | 18 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
| MYH10_ENST00000269243 | MYH10 | P35580 | Myosin-10 | chr17 | Not Cancer Driver | No | 1 | hippie | 258 | 1134 | 136 | 136 | 0 |
| MYH9 | MYH9 | P35579 | Myosin-9 | chr22 | Census, Compendium | Yes | 1 | hippie | 310 | 1120 | 160 | 160 | 17 |
| MYL6_ENST00000548293 | MYL6 | P60660 | Myosin light polypeptide 6 | chr12 | Not Cancer Driver | No | 1 | hippie | 13 | 17 | 1 | 1 | 0 |
| MYO1B | MYO1B | O43795 | Unconventional myosin-Ib | chr2 | Not Cancer Driver | No | 1 | hippie | 144 | 34 | 4 | 4 | 0 |
| MYO1C | MYO1C | O00159 | Unconventional myosin-Ic | chr17 | Not Cancer Driver | No | 1 | hippie | 110 | 66 | 11 | 11 | 0 |
| NANOG | NANOG | Q9H9S0 | Homeobox protein NANOG | chr12 | Not Cancer Driver | No | 1 | hippie | 46 | 169 | 35 | 35 | 0 |
| NCOA1_ENST00000348332 | NCOA1 | Q15788 | Nuclear receptor coactivator 1 | chr2 | Census, Compendium | Yes | 1 | hippie | 188 | 1217 | 149 | 149 | 0 |
| NCOA2 | NCOA2 | Q15596 | Nuclear receptor coactivator 2 | chr8 | Census, Compendium | Yes | 1 | hippie | 210 | 1281 | 185 | 185 | 0 |
| NCOA7_ENST00000368357 | NCOA7 | Q8NI08 | Nuclear receptor coactivator 7 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 110 | 538 | 63 | 63 | 0 |
| NCOR2 | NCOR2 | Q9Y618 | Nuclear receptor corepressor 2 | chr12 | Census, Compendium | Yes | 1 | intact, hippie | 373 | 2355 | 356 | 356 | 0 |
| NDOR1_ENST00000344894 | NDOR1 | Q9UHB4 | NADPH-dependent diflavin oxidoreductase 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 67 | 7 | 7 | 0 |
| NF2 | NF2 | P35240 | Merlin | chr22 | Census, Compendium | Yes | 1 | hippie | 69 | 252 | 26 | 26 | 16 |
| NONO | NONO | Q15233 | Non-POU domain-containing octamer-binding protein | chrX | Census, Compendium | Yes | 1 | hippie | 101 | 349 | 64 | 64 | 0 |
| NPAS1_ENST00000449844 | NPAS1 | Q99742 | Neuronal PAS domain-containing protein 1 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 53 | 309 | 23 | 23 | 0 |
| NPAS3 | NPAS3 | Q8IXF0 | Neuronal PAS domain-containing protein 3 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 190 | 505 | 111 | 111 | 0 |
| NPAS4 | NPAS4 | Q8IUM7 | Neuronal PAS domain-containing protein 4 | chr11 | Not Cancer Driver | No | 1 | hippie | 229 | 429 | 114 | 114 | 0 |
| OR6K3_ENST00000368146 | OR6K3 | Q8NGY3 | Olfactory receptor 6K3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 132 | 6 | 2 | 2 | 0 |
| PAX7_ENST00000420770 | PAX7 | P23759 | Paired box protein Pax-7 | chr1 | Census | Yes | 1 | intact, hippie | 97 | 401 | 77 | 77 | 1 |
| PCCB_ENST00000251654 | PCCB | P05166 | Propionyl-CoA carboxylase beta chain, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 64 | 12 | 12 | 25 |
| PDGFRA | PDGFRA | P16234 | Platelet-derived growth factor receptor alpha | chr4 | Census, Compendium | Yes | 1 | hippie | 290 | 173 | 45 | 45 | 2 |
| PDK1_ENST00000282077 | PDK1 | Q15118 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 52 | 50 | 10 | 10 | 0 |
| PFKFB3_ENST00000379775 | PFKFB3 | Q16875 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | chr10 | Not Cancer Driver | No | 1 | hippie | 65 | 97 | 19 | 19 | 0 |
| PFKFB4 | PFKFB4 | Q16877 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | chr3 | Not Cancer Driver | No | 1 | hippie | 71 | 44 | 3 | 3 | 0 |
| PFKM_ENST00000550924 | PFKM | P08237 | ATP-dependent 6-phosphofructokinase, muscle type | chr12 | Not Cancer Driver | No | 1 | hippie | 80 | 70 | 8 | 8 | 9 |
| PIAS2 | PIAS2 | O75928 | E3 SUMO-protein ligase PIAS2 | chr18 | Not Cancer Driver | No | 1 | hippie | 78 | 209 | 28 | 28 | 0 |
| PML | PML | P29590 | Protein PML | chr15 | Census, Compendium | Yes | 1 | hippie | 112 | 312 | 34 | 34 | 0 |
| PPA1 | PPA1 | Q15181 | Inorganic pyrophosphatase | chr10 | Not Cancer Driver | No | 1 | hippie | 31 | 24 | 0 | 0 | 0 |
| PPP1CA_ENST00000376745 | PPP1CA | P62136 | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | chr11 | Not Cancer Driver | No | 1 | hippie | 38 | 27 | 6 | 6 | 0 |
| PPP2R1A | PPP2R1A | P30153 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | chr19 | Census, Compendium | Yes | 1 | hippie | 179 | 0 | 0 | 0 | 4 |
| PSMD2 | PSMD2 | Q13200 | 26S proteasome non-ATPase regulatory subunit 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 100 | 135 | 14 | 14 | 0 |
| PTGES3_ENST00000262033 | PTGES3 | Q15185 | Prostaglandin E synthase 3 | chr12 | Not Cancer Driver | No | 1 | hippie | 11 | 52 | 3 | 3 | 0 |
| PXN_ENST00000228307 | PXN | P49023 | Paxillin | chr12 | Not Cancer Driver | No | 1 | hippie | 62 | 341 | 24 | 24 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
| RAF1 | RAF1 | P04049 | RAF proto-oncogene serine/threonine-protein kinase | chr3 | Census, Compendium | Yes | 1 | hippie | 89 | 169 | 38 | 38 | 22 |
| RANBP1_ENST00000331821 | RANBP1 | P43487 | Ran-specific GTPase-activating protein | chr22 | Not Cancer Driver | No | 1 | hippie | 19 | 137 | 16 | 16 | 0 |
| RB1 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | Census, Compendium | Yes | 1 | hippie | 140 | 282 | 32 | 32 | 22 |
| RELA | RELA | Q04206 | Transcription factor p65 | chr11 | Compendium | Yes | 1 | hippie | 75 | 400 | 48 | 48 | 0 |
| RPL18 | RPL18 | Q07020 | 60S ribosomal protein L18 | chr19 | Not Cancer Driver | No | 1 | hippie | 16 | 98 | 6 | 6 | 0 |
| RPL19 | RPL19 | P84098 | 60S ribosomal protein L19 | chr17 | Not Cancer Driver | No | 1 | hippie | 30 | 121 | 21 | 21 | 0 |
| RPL27_ENST00000253788 | RPL27 | P61353 | 60S ribosomal protein L27 | chr17 | Not Cancer Driver | No | 1 | hippie | 21 | 13 | 3 | 3 | 0 |
| RPL35A | RPL35A | P18077 | 60S ribosomal protein L35a | chr3 | Not Cancer Driver | No | 1 | hippie | 9 | 25 | 0 | 0 | 1 |
| RPL4 | RPL4 | P36578 | 60S ribosomal protein L4 | chr15 | Not Cancer Driver | No | 1 | hippie | 49 | 222 | 31 | 31 | 0 |
| RPL7 | RPL7 | P18124 | 60S ribosomal protein L7 | chr8 | Not Cancer Driver | No | 1 | hippie | 24 | 40 | 4 | 4 | 0 |
| RPS5_ENST00000601521 | RPS5 | P46782 | 40S ribosomal protein S5 | chr19 | Not Cancer Driver | No | 1 | hippie | 38 | 40 | 8 | 8 | 0 |
| RTL10_ENST00000407472 | RTL10 | Q7L3V2 | Protein Bop | chr22 | Not Cancer Driver | No | 1 | hippie | 52 | 196 | 31 | 31 | 0 |
| RTN4 | RTN4 | Q9NQC3 | Reticulon-4 | chr2 | Not Cancer Driver | No | 1 | hippie | 121 | 866 | 82 | 82 | 0 |
| RUVBL1 | RUVBL1 | Q9Y265 | RuvB-like 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 54 | 67 | 7 | 7 | 0 |
| RUVBL2 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 62 | 100 | 13 | 13 | 0 |
| S100A8 | S100A8 | P05109 | Protein S100-A8 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 8 | 4 | 4 | 0 |
| S100A9 | S100A9 | P06702 | Protein S100-A9 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 76 | 7 | 7 | 0 |
| SELENBP1_ENST00000368868 | SELENBP1 | Q13228 | Methanethiol oxidase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 32 | 5 | 5 | 2 |
| SENP6 | SENP6 | Q9GZR1 | Sentrin-specific protease 6 | chr6 | Not Cancer Driver | No | 1 | hippie | 120 | 612 | 59 | 59 | 0 |
| SFN | SFN | P31947 | 14-3-3 protein sigma | chr1 | Not Cancer Driver | No | 1 | hippie | 27 | 75 | 9 | 9 | 0 |
| SHARPIN | SHARPIN | Q9H0F6 | Sharpin | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 237 | 16 | 16 | 0 |
| SHMT1 | SHMT1 | P34896 | Serine hydroxymethyltransferase, cytosolic | chr17 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 51 | 32 | 7 | 7 | 0 |
| SIM1_ENST00000262901 | SIM1 | P81133 | Single-minded homolog 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 223 | 376 | 120 | 120 | 0 |
| SIM2 | SIM2 | Q14190 | Single-minded homolog 2 | chr21 | Not Cancer Driver | No | 2 | hippie, biogrid | 62 | 262 | 12 | 12 | 0 |
| SIPA1L3 | SIPA1L3 | O60292 | Signal-induced proliferation-associated 1-like protein 3 | chr19 | Not Cancer Driver | No | 1 | hippie | 273 | 1257 | 190 | 190 | 0 |
| SLC25A11 | SLC25A11 | Q02978 | Mitochondrial 2-oxoglutarate/malate carrier protein | chr17 | Not Cancer Driver | No | 1 | hippie | 37 | 16 | 1 | 1 | 3 |
| SLC7A5 | SLC7A5 | Q01650 | Large neutral amino acids transporter small subunit 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 62 | 35 | 1 | 1 | 0 |
| SLX1A_ENST00000345535 | SLX1A | Q9BQ83-2 | Isoform 2 of Structure-specific endonuclease subunit SLX1 | chr16 | Not Cancer Driver | No | 2 | hippie, biogrid | 5 | 27 | 0 | 0 | 0 |
| SMAD9 | SMAD9 | O15198 | Mothers against decapentaplegic homolog 9 | chr13 | Not Cancer Driver | No | 1 | hippie | 79 | 132 | 14 | 14 | 1 |
| SMARCA5 | SMARCA5 | O60264 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 | chr4 | Not Cancer Driver | No | 1 | hippie | 116 | 363 | 48 | 48 | 0 |
| SMG7_ENST00000347615 | SMG7 | Q92540 | Nonsense-mediated mRNA decay factor SMG7 | chr1 | Not Cancer Driver | No | 1 | hippie | 134 | 664 | 82 | 82 | 0 |
| SOX2 | SOX2 | P48431 | Transcription factor SOX-2 | chr3 | Census | Yes | 1 | intact, hippie | 39 | 312 | 39 | 39 | 0 |
| SOX6_ENST00000528429 | SOX6 | P35712 | Transcription factor SOX-6 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 130 | 744 | 118 | 118 | 0 |
| SP1 | SP1 | P08047 | Transcription factor Sp1 | chr12 | Not Cancer Driver | No | 1 | hippie | 96 | 599 | 71 | 71 | 0 |
| SP7 | SP7 | Q8TDD2 | Transcription factor Sp7 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 63 | 332 | 44 | 44 | 0 |
| SPTBN1 | SPTBN1 | Q01082 | Spectrin beta chain, non-erythrocytic 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 311 | 869 | 123 | 123 | 0 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | Census | Yes | 1 | hippie | 53 | 130 | 11 | 11 | 1 |
| STK11 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | Census, Compendium | Yes | 1 | hippie | 75 | 135 | 14 | 14 | 9 |
| STRBP_ENST00000348403 | STRBP | Q96SI9 | Spermatid perinuclear RNA-binding protein | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 74 | 306 | 31 | 31 | 0 |
| SUDS3 | SUDS3 | Q9H7L9 | Sin3 histone deacetylase corepressor complex component SDS3 | chr12 | Not Cancer Driver | No | 1 | hippie | 35 | 249 | 28 | 28 | 0 |
| SUGT1 | SUGT1 | Q9Y2Z0 | Protein SGT1 homolog | chr13 | Not Cancer Driver | No | 1 | hippie | 31 | 119 | 5 | 5 | 0 |
| SYT7_ENST00000263846 | SYT7 | O43581 | Synaptotagmin-7 | chr11 | Not Cancer Driver | No | 1 | hippie | 63 | 132 | 25 | 25 | 0 |
| TACC3 | TACC3 | Q9Y6A5 | Transforming acidic coiled-coil-containing protein 3 | chr4 | Not Cancer Driver | No | 1 | hippie | 98 | 707 | 81 | 81 | 0 |
| TEAD2_ENST00000311227 | TEAD2 | Q15562 | Transcriptional enhancer factor TEF-4 | chr19 | Not Cancer Driver | No | 1 | hippie | 66 | 220 | 31 | 31 | 0 |
| TERF2IP | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 310 | 16 | 16 | 0 |
| TGM2 | TGM2 | P21980 | Protein-glutamine gamma-glutamyltransferase 2 | chr20 | Not Cancer Driver | No | 1 | hippie | 123 | 107 | 26 | 26 | 0 |
| TIMM8A_ENST00000647359 | TIMM8A | O60220 | Mitochondrial import inner membrane translocase subunit Tim8 A | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 22 | 1 | 1 | 1 |
| TMPO | TMPO | P42166 | Lamina-associated polypeptide 2, isoform alpha | chr12 | Not Cancer Driver | No | 1 | hippie | 78 | 412 | 52 | 52 | 0 |
| TNFAIP1 | TNFAIP1 | Q13829 | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 35 | 39 | 5 | 5 | 0 |
| TNNC2 | TNNC2 | P02585 | Troponin C, skeletal muscle | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 87 | 13 | 13 | 0 |
| TNS3 | TNS3 | Q68CZ2 | Tensin-3 | chr7 | Not Cancer Driver | No | 1 | hippie | 238 | 864 | 143 | 143 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
| TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 430 | 41 | 41 | 0 |
| TRIP11 | TRIP11 | Q15643 | Thyroid receptor-interacting protein 11 | chr14 | Census, Compendium | Yes | 1 | hippie | 218 | 1364 | 161 | 161 | 2 |
| TUBB2A | TUBB2A | Q13885 | Tubulin beta-2A chain | chr6 | Not Cancer Driver | No | 1 | hippie | 44 | 70 | 13 | 13 | 2 |
| UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | Not Cancer Driver | No | 1 | hippie | 16 | 16 | 3 | 3 | 0 |
| VEGFA_ENST00000523873 | VEGFA | P15692 | Vascular endothelial growth factor A | chr6 | Not Cancer Driver | No | 1 | hippie | 27 | 41 | 7 | 7 | 0 |
| VHL | VHL | P40337 | von Hippel-Lindau disease tumor suppressor | chr3 | Census, Compendium | Yes | 1 | hippie, biogrid | 142 | 117 | 36 | 36 | 133 |
| XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie | 140 | 33 | 9 | 9 | 0 |
| XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | Not Cancer Driver | No | 1 | hippie | 66 | 140 | 12 | 12 | 0 |
| ZSCAN18_ENST00000240727 | ZSCAN18 | Q8TBC5 | Zinc finger and SCAN domain-containing protein 18 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 119 | 401 | 96 | 96 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|