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ARID4B ,ARID4B ,Q4LE39
  • Uniprot Accession= Q4LE39
  • Ensembl Transcript= ENST00000366603.6
  • Uniprot Name= ARID4B
  • Name= AT-rich interactive domain-containing protein 4B
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 17
  • Number of Interaction partner in biogrid: 62
  • Number of Interaction partner in hippie: 147
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AARSD1 AARSD1 Q9BTE6 Alanyl-tRNA editing protein Aarsd1 chr17 Not Cancer Driver No 1 intact, hippie 40 157 20 20 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie, biogrid 34 103 14 14 0
ARID4A ARID4A P29374 AT-rich interactive domain-containing protein 4A chr14 Not Cancer Driver No 1 hippie 151 978 123 123 0
AURKAIP1_ENST00000321751 AURKAIP1 Q9NWT8 Aurora kinase A-interacting protein chr1 Not Cancer Driver No 1 hippie 18 104 8 8 0
BCL11A BCL11A Q9H165 B-cell lymphoma/leukemia 11A chr2 Census, Compendium Yes 1 hippie, biogrid 210 677 171 171 3
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 Census, Compendium Yes 1 hippie, biogrid 156 699 114 114 2
BPTF_ENST00000321892 BPTF Q12830 Nucleosome-remodeling factor subunit BPTF chr17 Not Cancer Driver No 1 hippie, biogrid 309 2187 218 218 2
BRMS1L BRMS1L Q5PSV4 Breast cancer metastasis-suppressor 1-like protein chr14 Not Cancer Driver No 1 hippie, biogrid 35 160 17 17 0
BRPF3 BRPF3 Q9ULD4 Bromodomain and PHD finger-containing protein 3 chr6 Not Cancer Driver No 1 hippie 143 633 74 74 0
CASP1 CASP1 P29466 Caspase-1 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 79 87 18 18 0
CDK2AP1 CDK2AP1 O14519 Cyclin-dependent kinase 2-associated protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 10 76 8 8 0
CDK8 CDK8 P49336 Cyclin-dependent kinase 8 chr13 Not Cancer Driver No 1 hippie 76 152 18 18 7
CHAF1A CHAF1A Q13111 Chromatin assembly factor 1 subunit A chr19 Not Cancer Driver No 1 hippie, biogrid 133 767 99 99 0
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie, biogrid 235 1015 122 122 18
CHD5 CHD5 Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 365 931 183 183 0
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie 17 5 1 1 1
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CTSK CTSK P43235 Cathepsin K chr1 Not Cancer Driver No 3 hippie, biogrid 36 24 4 4 6
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 hippie 138 207 38 38 2
DDX41 DDX41 Q9UJV9 Probable ATP-dependent RNA helicase DDX41 chr5 Not Cancer Driver No 1 hippie, biogrid 82 180 26 26 1
DKK2 DKK2 Q9UBU2 Dickkopf-related protein 2 chr4 Not Cancer Driver No 1 hippie, biogrid 108 70 22 22 0
DYNLT1 DYNLT1 P63172 Dynein light chain Tctex-type 1 chr6 Not Cancer Driver No 1 hippie 7 1 0 0 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 Not Cancer Driver No 1 hippie 49 272 23 23 0
EAF1 EAF1 Q96JC9 ELL-associated factor 1 chr3 Not Cancer Driver No 1 intact, hippie 17 257 17 17 0
EED_ENST00000263360 EED O75530 Polycomb protein EED chr11 Census Yes 1 hippie, biogrid 64 79 11 11 6
ELF1 ELF1 P32519 ETS-related transcription factor Elf-1 chr13 Not Cancer Driver No 1 hippie 78 469 62 62 0
ELF2 ELF2 Q15723 ETS-related transcription factor Elf-2 chr4 Not Cancer Driver No 1 hippie 59 423 43 43 0
ELF4 ELF4 Q99607 ETS-related transcription factor Elf-4 chrX Census, Compendium Yes 1 hippie 88 486 60 60 0
ELK3 ELK3 P41970 ETS domain-containing protein Elk-3 chr12 Not Cancer Driver No 1 hippie 58 163 16 16 0
EN1 EN1 Q05925 Homeobox protein engrailed-1 chr2 Not Cancer Driver No 1 hippie 42 357 30 30 0
ERG_ENST00000288319 ERG P11308 Transcriptional regulator ERG chr21 Census, Compendium Yes 1 hippie 95 296 54 54 0
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 Not Cancer Driver No 1 hippie 68 78 9 9 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie, biogrid 120 284 44 44 11
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FEV FEV Q99581 Protein FEV chr2 Census Yes 1 hippie 15 55 0 0 0
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 30 0 0 0 0
FOXI1 FOXI1 Q12951 Forkhead box protein I1 chr5 Not Cancer Driver No 1 hippie 91 253 66 66 0
FOXK1 FOXK1 P85037 Forkhead box protein K1 chr7 Not Cancer Driver No 1 hippie 97 511 65 65 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 Not Cancer Driver No 1 hippie 79 548 64 64 0
FOXL1 FOXL1 Q12952 Forkhead box protein L1 chr16 Not Cancer Driver No 1 hippie 62 212 26 26 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 Census, Compendium Yes 1 hippie 72 370 49 49 6
GATAD1 GATAD1 Q8WUU5 GATA zinc finger domain-containing protein 1 chr7 Not Cancer Driver No 2 hippie, biogrid 14 131 4 4 1
GATAD2A_ENST00000360315 GATAD2A Q86YP4 Transcriptional repressor p66-alpha chr19 Not Cancer Driver No 1 hippie, biogrid 88 548 77 77 0
GATAD2B_ENST00000634544 GATAD2B Q8WXI9 Transcriptional repressor p66-beta chr1 Not Cancer Driver No 1 hippie, biogrid 76 510 67 67 0
GCM1 GCM1 Q9NP62 Chorion-specific transcription factor GCMa chr6 Not Cancer Driver No 1 hippie 78 194 36 36 0
GGH GGH Q92820 Gamma-glutamyl hydrolase chr8 Not Cancer Driver No 1 hippie 46 5 0 0 0
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 hippie 115 854 96 96 0
HAT1 HAT1 O14929 Histone acetyltransferase type B catalytic subunit chr2 Not Cancer Driver No 1 hippie, biogrid 51 14 2 2 0
HBP1_ENST00000468410 HBP1 O60381 HMG box-containing protein 1 chr7 Not Cancer Driver No 1 hippie 48 263 16 16 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 5 intact, hippie, biogrid 47 135 10 10 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 2 hippie, biogrid 46 145 14 14 0
HMGXB4 HMGXB4 Q9UGU5 HMG domain-containing protein 4 chr22 Not Cancer Driver No 1 hippie, biogrid 68 475 56 56 0
HNF4A HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 Not Cancer Driver No 1 hippie 135 127 48 48 5
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 Census, Compendium Yes 1 intact, hippie 68 255 41 41 0
ING1 ING1 Q9UK53 Inhibitor of growth protein 1 chr13 Compendium Yes 1 hippie, biogrid 69 209 33 33 3
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 Not Cancer Driver No 3 intact, hippie, biogrid 33 169 26 26 0
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 Not Cancer Driver No 1 hippie 37 43 1 1 0
INSIG2 INSIG2 Q9Y5U4 Insulin-induced gene 2 protein chr2 Not Cancer Driver No 1 hippie 47 11 3 3 0
IRF8 IRF8 Q02556 Interferon regulatory factor 8 chr16 Not Cancer Driver No 1 hippie 80 77 20 20 2
KIF11 KIF11 P52732 Kinesin-like protein KIF11 chr10 Not Cancer Driver No 1 intact, hippie 90 389 26 26 4
KLF10 KLF10 Q13118 Krueppel-like factor 10 chr8 Not Cancer Driver No 1 hippie 59 349 46 46 0
KLF12 KLF12 Q9Y4X4 Krueppel-like factor 12 chr13 Not Cancer Driver No 1 hippie 60 338 50 50 0
KLF15 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 Not Cancer Driver No 1 hippie 66 273 48 48 0
KLF16 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 hippie 13 204 8 8 0
KLF3 KLF3 P57682 Krueppel-like factor 3 chr4 Not Cancer Driver No 1 hippie 53 243 38 38 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 Compendium Yes 1 hippie 77 366 40 40 0
KLF8 KLF8 O95600 Krueppel-like factor 8 chrX Not Cancer Driver No 1 hippie 71 270 53 53 0
KLF9 KLF9 Q13886 Krueppel-like factor 9 chr9 Not Cancer Driver No 1 hippie 34 154 24 24 0
LACC1 LACC1 Q8IV20 Purine nucleoside phosphorylase LACC1 chr13 Not Cancer Driver No 3 intact, hippie, biogrid 50 4 0 0 1
LHX2 LHX2 P50458 LIM/homeobox protein Lhx2 chr9 Not Cancer Driver No 1 hippie 60 203 28 28 0
LIN37 LIN37 Q96GY3 Protein lin-37 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 34 239 34 34 0
LIN9 LIN9 Q5TKA1 Protein lin-9 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 67 219 25 25 0
MAX MAX P61244 Protein max chr14 Census, Compendium Yes 1 hippie, biogrid 45 160 45 45 9
MBD2 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 Not Cancer Driver No 1 hippie, biogrid 26 384 25 25 0
MBD3 MBD3 O95983 Methyl-CpG-binding domain protein 3 chr19 Not Cancer Driver No 1 hippie, biogrid 50 246 46 46 0
MLLT1 MLLT1 Q03111 Protein ENL chr19 Census, Compendium Yes 1 hippie, biogrid 68 413 43 43 0
MTA1 MTA1 Q13330 Metastasis-associated protein MTA1 chr14 Not Cancer Driver No 1 hippie, biogrid 92 327 42 42 0
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 Not Cancer Driver No 1 hippie, biogrid 78 283 32 32 0
MTA3 MTA3 Q9BTC8 Metastasis-associated protein MTA3 chr2 Not Cancer Driver No 1 hippie, biogrid 48 169 18 18 0
MTF2 MTF2 Q9Y483 Metal-response element-binding transcription factor 2 chr1 Not Cancer Driver No 1 hippie, biogrid 70 225 28 28 0
MXD1 MXD1 Q05195 Max dimerization protein 1 chr2 Not Cancer Driver No 3 hippie, biogrid 27 171 24 24 0
MXD3_ENST00000513063 MXD3 Q9BW11 Max dimerization protein 3 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 17 156 13 13 0
MYBL2 MYBL2 P10244 Myb-related protein B chr20 Not Cancer Driver No 1 hippie, biogrid 111 506 85 85 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 Census Yes 1 hippie 45 246 33 33 0
NFIA_ENST00000403491 NFIA Q12857 Nuclear factor 1 A-type chr1 Not Cancer Driver No 1 hippie 78 347 55 55 0
NFIC NFIC P08651 Nuclear factor 1 C-type chr19 Not Cancer Driver No 1 hippie 61 327 44 44 0
NFIX_ENST00000592199 NFIX Q14938 Nuclear factor 1 X-type chr19 Not Cancer Driver No 1 hippie 60 305 40 40 6
NFYC NFYC Q13952 Nuclear transcription factor Y subunit gamma chr1 Not Cancer Driver No 1 hippie 46 320 32 32 0
NHLH1 NHLH1 Q02575 Helix-loop-helix protein 1 chr1 Not Cancer Driver No 1 hippie 30 90 22 22 0
NHSL2 NHSL2 Q5HYW2 NHS-like protein 2 chrX Not Cancer Driver No 1 intact, hippie 123 1127 119 119 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 119 320 34 34 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 Not Cancer Driver No 1 hippie 62 296 48 48 23
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 Not Cancer Driver No 1 hippie 72 337 56 56 38
PAX7_ENST00000420770 PAX7 P23759 Paired box protein Pax-7 chr1 Census Yes 1 hippie 97 401 77 77 1
PAX9 PAX9 P55771 Paired box protein Pax-9 chr14 Not Cancer Driver No 1 hippie 52 198 32 32 1
PHF1 PHF1 O43189 PHD finger protein 1 chr6 Not Cancer Driver No 2 hippie, biogrid 62 277 29 29 0
PHF12 PHF12 Q96QT6 PHD finger protein 12 chr17 Not Cancer Driver No 1 hippie, biogrid 107 619 68 68 0
PHF23 PHF23 Q9BUL5 PHD finger protein 23 chr17 Not Cancer Driver No 2 hippie, biogrid 45 331 37 37 0
PIH1D3_ENST00000372453 DNAAF6 Q9NQM4 Dynein axonemal assembly factor 6 chrX Not Cancer Driver No 1 intact 23 114 12 12 1
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 Not Cancer Driver No 1 hippie 51 149 20 20 0
PLEKHF2 PLEKHF2 Q9H8W4 Pleckstrin homology domain-containing family F member 2 chr8 Not Cancer Driver No 1 hippie 32 36 4 4 0
PRR23B PRR23B Q6ZRT6 Proline-rich protein 23B chr3 Not Cancer Driver No 1 intact, hippie 116 167 66 66 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie 23 67 6 6 0
PWWP2A PWWP2A Q96N64 PWWP domain-containing protein 2A chr5 Census Yes 1 hippie, biogrid 57 601 46 46 0
RANBP2 RANBP2 P49792 E3 SUMO-protein ligase RanBP2 chr2 Census, Compendium Yes 1 hippie 427 1387 177 177 3
RBBP4 RBBP4 Q09028 Histone-binding protein RBBP4 chr1 Not Cancer Driver No 2 hippie, biogrid 53 169 23 23 0
RBBP7_ENST00000380087 RBBP7 Q16576 Histone-binding protein RBBP7 chrX Not Cancer Driver No 3 intact, hippie, biogrid 67 138 19 19 0
RPS26_ENST00000646449 RPS26 P62854 40S ribosomal protein S26 chr12 Not Cancer Driver No 1 hippie, biogrid 9 52 5 5 2
S100A2_ENST00000368709 S100A2 P29034 Protein S100-A2 chr1 Not Cancer Driver No 1 hippie, biogrid 16 6 2 2 0
SAP130_ENST00000259235 SAP130 Q9H0E3 Histone deacetylase complex subunit SAP130 chr2 Not Cancer Driver No 3 hippie, biogrid 119 940 107 107 0
SAP30 SAP30 O75446 Histone deacetylase complex subunit SAP30 chr4 Not Cancer Driver No 4 hippie, biogrid 26 123 17 17 0
SHPRH SHPRH Q149N8 E3 ubiquitin-protein ligase SHPRH chr6 Not Cancer Driver No 1 hippie, biogrid 227 359 51 51 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 Compendium Yes 3 hippie, biogrid 172 617 73 73 0
SIN3B SIN3B O75182 Paired amphipathic helix protein Sin3b chr19 Not Cancer Driver No 2 hippie, biogrid 130 316 32 32 0
SINHCAF_ENST00000454658 SINHCAF Q9NP50 SIN3-HDAC complex-associated factor chr12 Not Cancer Driver No 1 intact, hippie 24 108 10 10 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 Not Cancer Driver No 1 hippie 70 435 31 31 0
SMARCA1_ENST00000371122 SMARCA1 P28370 Probable global transcription activator SNF2L1 chrX Compendium Yes 1 hippie, biogrid 143 309 41 41 0
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 Not Cancer Driver No 1 hippie 66 421 62 62 14
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SOX5 SOX5 P35711 Transcription factor SOX-5 chr12 Not Cancer Driver No 1 hippie 182 665 162 162 0
SOX6_ENST00000528429 SOX6 P35712 Transcription factor SOX-6 chr11 Not Cancer Driver No 1 hippie 130 744 118 118 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 Compendium Yes 1 hippie 86 495 82 82 18
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 hippie 63 332 44 44 0
SUDS3 SUDS3 Q9H7L9 Sin3 histone deacetylase corepressor complex component SDS3 chr12 Not Cancer Driver No 2 hippie, biogrid 35 249 28 28 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TBR1 TBR1 Q16650 T-box brain protein 1 chr2 Not Cancer Driver No 1 hippie 88 413 56 56 5
TBXT TBXT O15178 T-box transcription factor T chr6 Not Cancer Driver No 1 hippie 110 253 69 69 1
TEAD1_ENST00000638666 TEAD1 P28347 Transcriptional enhancer factor TEF-1 chr11 Not Cancer Driver No 1 hippie 52 157 24 24 1
TGIF2LX_ENST00000283891 TGIF2LX Q8IUE1 Homeobox protein TGIF2LX chrX Not Cancer Driver No 1 hippie, biogrid 117 215 101 101 0
TGIF2_ENST00000611732 TGIF2 Q9GZN2 Homeobox protein TGIF2 chr20 Not Cancer Driver No 1 hippie, biogrid 37 171 23 23 0
TLX1 TLX1 P31314 T-cell leukemia homeobox protein 1 chr10 Census Yes 1 hippie 28 223 17 17 0
TLX3 TLX3 O43711 T-cell leukemia homeobox protein 3 chr5 Census Yes 1 hippie 40 179 24 24 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TRAF3IP1 TRAF3IP1 Q8TDR0 TRAF3-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 75 507 60 60 4
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WDYHV1 NTAQ1 Q96HA8 Protein N-terminal glutamine amidohydrolase chr8 Not Cancer Driver No 1 intact 38 26 3 3 0
YAF2_ENST00000534854 YAF2 Q8IY57 YY1-associated factor 2 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 27 166 27 27 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 Not Cancer Driver No 1 hippie 37 336 26 26 2
ZNF219 ZNF219 Q9P2Y4 Zinc finger protein 219 chr14 Not Cancer Driver No 1 hippie, biogrid 44 628 37 37 0
ZNF330 ZNF330 Q9Y3S2 Zinc finger protein 330 chr4 Not Cancer Driver No 1 hippie, biogrid 44 127 19 19 0
ZNF512B ZNF512B Q96KM6 Zinc finger protein 512B chr20 Not Cancer Driver No 1 hippie, biogrid 101 694 83 83 0
ZNF704 ZNF704 Q6ZNC4 Zinc finger protein 704 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 64 336 55 55 0