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ARHGEF2 ,ARHGEF2 ,Q92974
  • Uniprot Accession= Q92974
  • Ensembl Transcript= ENST00000361247.8
  • Uniprot Name= ARHGEF2
  • Name= Rho guanine nucleotide exchange factor 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 39
  • Number of Interaction partner in biogrid: 43
  • Number of Interaction partner in hippie: 166
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AKAP10 AKAP10 O43572 A-kinase anchor protein 10, mitochondrial chr17 Not Cancer Driver No 1 hippie 51 304 16 16 0
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 Census, Compendium Yes 1 intact 303 575 114 114 16
ANKRD28 ANKRD28 O15084 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A chr3 Not Cancer Driver No 1 intact, hippie, biogrid 121 115 15 15 0
ANKRD52 ANKRD52 Q8NB46 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C chr12 Not Cancer Driver No 1 hippie 123 67 3 3 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
APOO APOO Q9BUR5 MICOS complex subunit MIC26 chrX Not Cancer Driver No 1 hippie, biogrid 25 23 4 4 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 Not Cancer Driver No 1 hippie 146 450 70 70 0
ASAP1 ASAP1 Q9ULH1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 chr8 Not Cancer Driver No 1 hippie 183 584 108 108 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
AURKAIP1_ENST00000321751 AURKAIP1 Q9NWT8 Aurora kinase A-interacting protein chr1 Not Cancer Driver No 1 hippie 18 104 8 8 0
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 hippie 37 63 7 7 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BET1 BET1 O15155 BET1 homolog chr7 Not Cancer Driver No 1 hippie 14 7 2 2 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
CAMSAP1 CAMSAP1 Q5T5Y3 Calmodulin-regulated spectrin-associated protein 1 chr9 Not Cancer Driver No 1 hippie 208 1129 158 158 0
CAMSAP2 CAMSAP2 Q08AD1 Calmodulin-regulated spectrin-associated protein 2 chr1 Not Cancer Driver No 1 hippie 176 1025 127 127 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 100 618 77 77 0
CEP170 CEP170 Q5SW79 Centrosomal protein of 170 kDa chr1 Not Cancer Driver No 1 intact, hippie 264 1429 246 246 0
CEP170B_ENST00000556508 CEP170B Q9Y4F5 Centrosomal protein of 170 kDa protein B chr14 Not Cancer Driver No 1 hippie 126 1438 117 117 0
CEP250 CEP250 Q9BV73 Centrosome-associated protein CEP250 chr20 Not Cancer Driver No 1 hippie 250 1859 195 195 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact, hippie 287 145 18 18 151
CGN CGN Q9P2M7 Cingulin chr1 Not Cancer Driver No 1 hippie 152 1179 149 149 0
CIAO2A CIAO2A Q9H5X1 Cytosolic iron-sulfur assembly component 2A chr15 Not Cancer Driver No 1 hippie 24 28 4 4 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CKAP2 CKAP2 Q8WWK9 Cytoskeleton-associated protein 2 chr13 Not Cancer Driver No 1 hippie 72 522 57 57 0
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 Not Cancer Driver No 1 hippie 163 642 70 70 0
CNTRL_ENST00000238341 CNTRL Q7Z7A1 Centriolin chr9 Census Yes 1 hippie 234 1556 159 159 0
COPS7A_ENST00000534947 COPS7A Q9UBW8 COP9 signalosome complex subunit 7a chr12 Not Cancer Driver No 1 hippie, biogrid 32 74 10 10 0
DCLK1 DCLK1 O15075 Serine/threonine-protein kinase DCLK1 chr13 Not Cancer Driver No 1 hippie 209 252 77 77 0
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 Census Yes 2 intact, hippie, biogrid 172 817 111 111 11
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DVL1 DVL1 O14640 Segment polarity protein dishevelled homolog DVL-1 chr1 Not Cancer Driver No 1 hippie 73 434 38 38 0
DYNLT1 DYNLT1 P63172 Dynein light chain Tctex-type 1 chr6 Not Cancer Driver No 1 hippie 7 1 0 0 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 77 294 39 39 0
EEF1AKMT3 EEF1AKMT3 Q96AZ1 EEF1A lysine methyltransferase 3 chr12 Not Cancer Driver No 1 hippie 23 33 1 1 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FBXO45 FBXO45 P0C2W1 F-box/SPRY domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 28 10 0 0 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 intact 152 230 43 43 74
FGL1_ENST00000381840 FGL1 Q08830 Fibrinogen-like protein 1 chr8 Not Cancer Driver No 3 intact, hippie, biogrid 42 10 2 2 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 Census, Compendium Yes 1 intact, hippie 70 595 68 68 0
FTSJ3 FTSJ3 Q8IY81 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 chr17 Not Cancer Driver No 1 hippie, biogrid 103 533 66 66 0
FYB1_ENST00000515010 FYB1 O15117 FYN-binding protein 1 chr5 Not Cancer Driver No 1 intact, hippie 176 687 161 161 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GTSE1 GTSE1 Q9NYZ3 G2 and S phase-expressed protein 1 chr22 Not Cancer Driver No 1 hippie 91 660 85 85 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HECTD1 HECTD1 Q9ULT8 E3 ubiquitin-protein ligase HECTD1 chr14 Not Cancer Driver No 1 hippie, biogrid 274 991 108 108 0
HNRNPCL2 HNRNPCL2 B2RXH8 Heterogeneous nuclear ribonucleoprotein C-like 2 chr1 Not Cancer Driver No 1 hippie, biogrid 51 199 41 41 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 2 intact, hippie 149 251 52 52 0
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KLC2_ENST00000394067 KLC2 Q9H0B6 Kinesin light chain 2 chr11 Not Cancer Driver No 1 hippie, biogrid 75 344 49 49 0
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 intact, hippie 114 404 58 58 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LRRC31 LRRC31 Q6UY01 Leucine-rich repeat-containing protein 31 chr3 Not Cancer Driver No 1 hippie 109 80 10 10 0
LURAP1L LURAP1L Q8IV03 Leucine rich adaptor protein 1-like chr9 Not Cancer Driver No 1 hippie, biogrid 31 142 16 16 0
MAP1S MAP1S Q66K74 Microtubule-associated protein 1S chr19 Not Cancer Driver No 1 hippie 118 527 48 48 0
MAP3K14 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 Not Cancer Driver No 1 intact, hippie 94 543 52 52 0
MAP7D2_ENST00000379651 MAP7D2 Q96T17 MAP7 domain-containing protein 2 chrX Not Cancer Driver No 1 hippie 124 723 120 120 0
MAP7D3 MAP7D3 Q8IWC1 MAP7 domain-containing protein 3 chrX Not Cancer Driver No 1 hippie 131 847 127 127 0
MAP7_ENST00000354570 MAP7 Q14244 Ensconsin chr6 Not Cancer Driver No 1 hippie 122 745 122 122 0
MAP9 MAP9 Q49MG5 Microtubule-associated protein 9 chr4 Not Cancer Driver No 1 hippie 118 622 116 116 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 62 2 0 0 7
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 Not Cancer Driver No 1 hippie 26 109 11 11 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 Not Cancer Driver No 1 hippie, biogrid 37 120 16 16 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 Compendium Yes 1 hippie, biogrid 124 445 70 70 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 hippie, biogrid 92 376 49 49 1
MARK4 MARK4 Q96L34 MAP/microtubule affinity-regulating kinase 4 chr19 Not Cancer Driver No 1 intact, hippie 94 403 46 46 0
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 287 749 159 159 3
MMS19 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 Not Cancer Driver No 1 hippie 73 11 0 0 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MTUS1 MTUS1 Q9ULD2 Microtubule-associated tumor suppressor 1 chr8 Not Cancer Driver No 1 hippie 127 978 106 106 4
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 1 hippie 48 111 17 17 0
NEDD1_ENST00000266742 NEDD1 Q8NHV4 Protein NEDD1 chr12 Not Cancer Driver No 1 hippie 87 282 36 36 0
NFKBID NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 Not Cancer Driver No 1 intact, hippie 47 124 20 20 0
NFKBIE NFKBIE O00221 NF-kappa-B inhibitor epsilon chr6 Census, Compendium Yes 1 hippie 41 284 16 16 0
NIN NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 239 1392 164 164 2
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 1 hippie 363 686 87 87 3
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUDCD1 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 intact 75 38 4 4 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 1 hippie 57 299 30 30 2
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 Not Cancer Driver No 1 hippie 58 340 33 33 0
PAK5 PAK5 Q9P286 Serine/threonine-protein kinase PAK 5 chr20 Not Cancer Driver No 1 intact, hippie 226 407 123 123 0
PDZD11_ENST00000374454 PDZD11 Q5EBL8 PDZ domain-containing protein 11 chrX Not Cancer Driver No 1 hippie 20 46 8 8 0
PEX14 PEX14 O75381 Peroxisomal membrane protein PEX14 chr1 Not Cancer Driver No 2 hippie, biogrid 38 266 28 28 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie 158 186 21 21 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHA5_ENST00000299275 PLEKHA5 Q9HAU0 Pleckstrin homology domain-containing family A member 5 chr12 Not Cancer Driver No 1 hippie 144 869 114 114 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 87 119 13 13 0
PLS3_ENST00000539310 PLS3 P13797 Plastin-3 chrX Not Cancer Driver No 1 hippie 75 75 5 5 0
PNMA2 PNMA2 Q9UL42 Paraneoplastic antigen Ma2 chr8 Not Cancer Driver No 1 hippie, biogrid 52 45 5 5 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 1 intact, hippie 41 12 1 1 8
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 Not Cancer Driver No 2 intact, hippie 37 12 0 0 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 2 intact, hippie, biogrid 179 0 0 0 4
PPP2R2A_ENST00000380737 PPP2R2A P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform chr8 Not Cancer Driver No 1 intact, hippie 60 68 10 10 0
PPP2R5A PPP2R5A Q15172 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform chr1 Not Cancer Driver No 2 hippie, biogrid 55 93 5 5 0
PPP2R5B PPP2R5B Q15173 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform chr11 Not Cancer Driver No 2 intact, hippie, biogrid 79 119 9 9 0
PPP2R5D PPP2R5D Q14738 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform chr6 Not Cancer Driver No 1 hippie 64 178 13 13 4
PPP2R5E PPP2R5E Q16537 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform chr14 Not Cancer Driver No 1 intact, hippie 68 86 20 20 0
PPP6C_ENST00000373547 PPP6C O00743 Serine/threonine-protein phosphatase 6 catalytic subunit chr9 Census, Compendium Yes 2 intact, hippie, biogrid 63 0 0 0 0
PPP6R1_ENST00000587283 PPP6R1 Q9UPN7 Serine/threonine-protein phosphatase 6 regulatory subunit 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 82 471 47 47 0
PPP6R2_ENST00000216061 PPP6R2 O75170 Serine/threonine-protein phosphatase 6 regulatory subunit 2 chr22 Not Cancer Driver No 1 hippie 103 491 63 63 0
PPP6R3_ENST00000393800 PPP6R3 Q5H9R7 Serine/threonine-protein phosphatase 6 regulatory subunit 3 chr11 Not Cancer Driver No 1 hippie 108 389 52 52 0
PRDM16 PRDM16 Q9HAZ2 Histone-lysine N-methyltransferase PRDM16 chr1 Census Yes 1 hippie 254 830 152 152 1
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 Not Cancer Driver No 1 hippie, biogrid 22 40 5 5 0
PSME3_ENST00000590720 PSME3 P61289 Proteasome activator complex subunit 3 chr17 Not Cancer Driver No 1 hippie, biogrid 20 25 5 5 0
PTBP3_ENST00000374255 PTBP3 O95758 Polypyrimidine tract-binding protein 3 chr9 Not Cancer Driver No 1 intact, hippie 61 114 9 9 0
PTPRF PTPRF P10586 Receptor-type tyrosine-protein phosphatase F chr1 Not Cancer Driver No 1 hippie 268 696 96 96 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 hippie 62 341 24 24 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie 59 328 43 43 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 3 hippie, biogrid 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 2 hippie, biogrid 52 19 2 2 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 Not Cancer Driver No 1 hippie 142 319 45 45 0
ROS1 ROS1 P08922 Proto-oncogene tyrosine-protein kinase ROS chr6 Census Yes 1 intact 498 191 55 55 0
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 51 98 6 6 0
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie 28 114 16 16 0
RPA3 RPA3 P35244 Replication protein A 14 kDa subunit chr7 Not Cancer Driver No 1 hippie 13 4 1 1 0
RPL26L1 RPL26L1 Q9UNX3 60S ribosomal protein L26-like 1 chr5 Not Cancer Driver No 1 hippie, biogrid 21 107 11 11 0
RPP25L RPP25L Q8N5L8 Ribonuclease P protein subunit p25-like protein chr9 Not Cancer Driver No 4 intact, hippie, biogrid 31 113 18 18 0
RRAS2 RRAS2 P62070 Ras-related protein R-Ras2 chr11 Compendium Yes 1 hippie 29 37 1 1 4
SCLT1 SCLT1 Q96NL6 Sodium channel and clathrin linker 1 chr4 Not Cancer Driver No 1 intact, hippie 98 398 61 61 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 33 164 12 12 0
SKA1_ENST00000398452 SKA1 Q96BD8 Spindle and kinetochore-associated protein 1 chr18 Not Cancer Driver No 1 hippie 23 74 7 7 0
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie 38 416 37 37 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 62 488 56 56 0
SPSB4 SPSB4 Q96A44 SPRY domain-containing SOCS box protein 4 chr3 Not Cancer Driver No 1 hippie, biogrid 42 75 3 3 0
SRP54 SRP54 P61011 Signal recognition particle 54 kDa protein chr14 Not Cancer Driver No 1 hippie 53 115 13 13 7
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
TAF10 TAF10 Q12962 Transcription initiation factor TFIID subunit 10 chr11 Not Cancer Driver No 1 hippie, biogrid 17 131 4 4 0
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 Not Cancer Driver No 1 intact 198 1350 151 151 0
TRIM36 TRIM36 Q9NQ86 E3 ubiquitin-protein ligase TRIM36 chr5 Not Cancer Driver No 1 hippie, biogrid 106 89 21 21 1
TRIM52 TRIM52 Q96A61 E3 ubiquitin-protein ligase TRIM52 chr5 Not Cancer Driver No 1 hippie, biogrid 23 147 13 13 0
TULP3_ENST00000448120 TULP3 O75386 Tubby-related protein 3 chr12 Not Cancer Driver No 1 hippie 66 218 29 29 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX Compendium Yes 1 hippie 35 67 13 13 2
UBXN6 UBXN6 Q9BZV1 UBX domain-containing protein 6 chr19 Not Cancer Driver No 1 hippie, biogrid 64 132 26 26 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
USE1 USE1 Q9NZ43 Vesicle transport protein USE1 chr19 Not Cancer Driver No 1 hippie 31 101 19 19 0
USP21_ENST00000289865 USP21 Q9UK80 Ubiquitin carboxyl-terminal hydrolase 21 chr1 Not Cancer Driver No 1 hippie 95 230 47 47 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VPS33B VPS33B Q9H267 Vacuolar protein sorting-associated protein 33B chr15 Not Cancer Driver No 1 hippie 54 17 0 0 2
WASF1_ENST00000392586 WASF1 Q92558 Wiskott-Aldrich syndrome protein family member 1 chr6 Not Cancer Driver No 1 hippie 63 445 49 49 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie 30 35 3 3 0
WDR83 WDR83 Q9BRX9 WD repeat domain-containing protein 83 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 28 35 3 3 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 3 intact, hippie, biogrid 22 109 4 4 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 3 intact, hippie, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 3 intact, hippie, biogrid 15 55 3 3 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 3 intact, hippie, biogrid 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 4 intact, hippie, biogrid 30 81 10 10 0
ZBTB44_ENST00000357899 ZBTB44 Q8NCP5 Zinc finger and BTB domain-containing protein 44 chr11 Not Cancer Driver No 1 hippie, biogrid 68 266 35 35 0
ZNRF2 ZNRF2 Q8NHG8 E3 ubiquitin-protein ligase ZNRF2 chr7 Not Cancer Driver No 1 hippie, biogrid 12 147 0 0 0