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ARHGEF16 ,ARHGEF16 ,Q5VV41
  • Uniprot Accession= Q5VV41
  • Ensembl Transcript= ENST00000378378.8
  • Uniprot Name= ARHGEF16
  • Name= Rho guanine nucleotide exchange factor 16
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 5
  • Number of Interaction partner in biogrid: 54
  • Number of Interaction partner in hippie: 77
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCD3 ABCD3 P28288 ATP-binding cassette sub-family D member 3 chr1 Not Cancer Driver No 1 hippie, biogrid 75 21 2 2 0
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 45 32 1 1 10
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 Not Cancer Driver No 1 hippie 88 156 20 20 4
ANKFY1_ENST00000341657 ANKFY1 Q9P2R3 Rabankyrin-5 chr17 Not Cancer Driver No 1 hippie, biogrid 109 185 29 29 0
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 230 161 34 34 8
ATP5PO ATP5PO P48047 ATP synthase subunit O, mitochondrial chr21 Not Cancer Driver No 1 hippie 19 9 2 2 0
BOLL_ENST00000392296 BOLL Q8N9W6 Protein boule-like chr2 Not Cancer Driver No 1 hippie 59 78 22 22 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CEP55 CEP55 Q53EZ4 Centrosomal protein of 55 kDa chr10 Not Cancer Driver No 1 intact, hippie 59 264 26 26 0
CHCHD2 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 Not Cancer Driver No 1 hippie, biogrid 24 114 21 21 1
CKAP5 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 Not Cancer Driver No 1 hippie 198 634 64 64 0
COQ8A COQ8A Q8NI60 Atypical kinase COQ8A, mitochondrial chr1 Not Cancer Driver No 1 hippie 95 166 29 29 12
DLAT DLAT P10515 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 63 294 42 42 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 Not Cancer Driver No 2 hippie, biogrid 120 460 67 67 0
DPP8_ENST00000559233 DPP8 Q6V1X1 Dipeptidyl peptidase 8 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 99 71 5 5 0
ELMO1_ENST00000448602 ELMO1 Q92556 Engulfment and cell motility protein 1 chr7 Not Cancer Driver No 1 hippie 199 98 22 22 0
EPB41L3 EPB41L3 Q9Y2J2 Band 4.1-like protein 3 chr18 Not Cancer Driver No 1 hippie, biogrid 298 695 207 207 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 1 hippie 171 187 39 39 3
FGD6 FGD6 Q6ZV73 FYVE, RhoGEF and PH domain-containing protein 6 chr12 Not Cancer Driver No 1 hippie, biogrid 198 804 117 117 0
GAPDHS GAPDHS O14556 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific chr19 Not Cancer Driver No 1 hippie, biogrid 71 111 19 19 0
GAR1 GAR1 Q9NY12 H/ACA ribonucleoprotein complex subunit 1 chr4 Not Cancer Driver No 1 hippie, biogrid 23 141 14 14 0
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 1 hippie 216 669 76 76 0
HACD3 HACD3 Q9P035 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 chr15 Not Cancer Driver No 1 hippie 28 10 0 0 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie, biogrid 46 145 14 14 0
HMGN1 HMGN1 P05114 Non-histone chromosomal protein HMG-14 chr21 Not Cancer Driver No 1 hippie, biogrid 12 100 12 12 0
HMGN3_ENST00000344726 HMGN3 Q15651 High mobility group nucleosome-binding domain-containing protein 3 chr6 Not Cancer Driver No 1 hippie, biogrid 14 99 14 14 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 107 16 4 4 18
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie, biogrid 149 251 52 52 0
IFT122_ENST00000348417 IFT122 Q9HBG6 Intraflagellar transport protein 122 homolog chr3 Not Cancer Driver No 2 hippie, biogrid 157 54 5 5 5
KPNA2_ENST00000330459 KPNA2 P52292 Importin subunit alpha-1 chr17 Not Cancer Driver No 1 hippie, biogrid 74 129 18 18 0
LASP1 LASP1 Q14847 LIM and SH3 domain protein 1 chr17 Census Yes 1 hippie 29 198 24 24 0
LBR_ENST00000272163 LBR Q14739 Delta(14)-sterol reductase LBR chr1 Not Cancer Driver No 1 hippie, biogrid 95 130 15 15 5
LIN7C LIN7C Q9NUP9 Protein lin-7 homolog C chr11 Not Cancer Driver No 1 hippie, biogrid 22 102 11 11 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
LNX1 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 Not Cancer Driver No 1 hippie 117 261 40 40 0
LRIF1 LRIF1 Q5T3J3 Ligand-dependent nuclear receptor-interacting factor 1 chr1 Not Cancer Driver No 1 hippie 116 520 74 74 0
LYPLA1 LYPLA1 O75608 Acyl-protein thioesterase 1 chr8 Not Cancer Driver No 1 hippie, biogrid 19 12 2 2 0
MAGED1_ENST00000326587 MAGED1 Q9Y5V3 Melanoma-associated antigen D1 chrX Not Cancer Driver No 1 hippie 131 457 71 71 0
MAPK1IP1L_ENST00000622254 MAPK1IP1L Q8NDC0 MAPK-interacting and spindle-stabilizing protein-like chr14 Not Cancer Driver No 1 hippie 25 245 25 25 0
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 Not Cancer Driver No 1 hippie, biogrid 26 109 11 11 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX Not Cancer Driver No 1 hippie, biogrid 75 483 74 74 46
MGA MGA Q8IWI9 MAX gene-associated protein chr15 Compendium Yes 1 hippie, biogrid 341 2317 259 259 0
MRPL53 MRPL53 Q96EL3 39S ribosomal protein L53, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 20 22 1 1 0
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 Not Cancer Driver No 1 hippie, biogrid 21 37 3 3 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PML PML P29590 Protein PML chr15 Census, Compendium Yes 2 intact, hippie, biogrid 112 312 34 34 0
PPIB PPIB P23284 Peptidyl-prolyl cis-trans isomerase B chr15 Not Cancer Driver No 1 hippie, biogrid 28 16 1 1 1
PPIL4 PPIL4 Q8WUA2 Peptidyl-prolyl cis-trans isomerase-like 4 chr6 Not Cancer Driver No 1 hippie, biogrid 62 237 34 34 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 Not Cancer Driver No 1 hippie, biogrid 110 120 16 16 0
QPCTL QPCTL Q9NXS2 Glutaminyl-peptide cyclotransferase-like protein chr19 Not Cancer Driver No 1 hippie, biogrid 42 22 1 1 0
RABL3 RABL3 Q5HYI8 Rab-like protein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 37 1 0 0 1
RBFOX2_ENST00000449924 RBFOX2 O43251 RNA binding protein fox-1 homolog 2 chr22 Compendium Yes 1 hippie, biogrid 44 173 22 22 0
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie, biogrid 52 19 2 2 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 Not Cancer Driver No 1 hippie, biogrid 287 1355 164 164 0
RPL22L1 RPL22L1 Q6P5R6 60S ribosomal protein L22-like 1 chr3 Not Cancer Driver No 1 hippie, biogrid 16 22 4 4 0
RPS27A_ENST00000404735 RPS27A P62979 Ubiquitin-40S ribosomal protein S27a chr2 Not Cancer Driver No 1 hippie, biogrid 18 47 2 2 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 Not Cancer Driver No 2 hippie, biogrid 196 1064 135 135 2
SF3A1 SF3A1 Q15459 Splicing factor 3A subunit 1 chr22 Not Cancer Driver No 1 hippie, biogrid 82 631 67 67 0
SFN SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 27 75 9 9 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 57 58 5 5 1
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie, biogrid 38 416 37 37 0
SNTB2 SNTB2 Q13425 Beta-2-syntrophin chr16 Not Cancer Driver No 1 hippie, biogrid 28 163 3 3 0
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 74 270 39 39 0
TAB1 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 81 232 34 34 0
TFG TFG Q92734 Protein TFG chr3 Census, Compendium Yes 1 hippie 45 290 34 34 3
TMEM160 TMEM160 Q9NX00 Transmembrane protein 160 chr19 Not Cancer Driver No 1 hippie, biogrid 8 46 1 1 0
UBAC1 UBAC1 Q9BSL1 Ubiquitin-associated domain-containing protein 1 chr9 Not Cancer Driver No 2 hippie, biogrid 38 241 23 23 0
UTRN UTRN P46939 Utrophin chr6 Not Cancer Driver No 1 hippie, biogrid 476 1283 183 183 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie, biogrid 140 33 9 9 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 2 hippie, biogrid 22 109 4 4 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 hippie, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 2 hippie, biogrid 15 55 3 3 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 2 hippie, biogrid 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 2 hippie, biogrid 30 81 10 10 0