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ARF1_ENST00000272102 ,ARF1 ,P84077
  • Number of Interaction partner in intact: 37
  • Number of Interaction partner in biogrid: 133
  • Number of Interaction partner in hippie: 202
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ACADM_ENST00000370841 ACADM P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 61 41 5 5 19
ADCK1 ADCK1 Q86TW2 AarF domain-containing protein kinase 1 chr14 Not Cancer Driver No 1 intact, hippie 82 6 3 3 0
ADCK2 ADCK2 Q7Z695 Uncharacterized aarF domain-containing protein kinase 2 chr7 Not Cancer Driver No 1 hippie 62 9 1 1 0
ADCK5 ADCK5 Q3MIX3 Uncharacterized aarF domain-containing protein kinase 5 chr8 Not Cancer Driver No 1 intact, hippie 51 5 2 2 0
AGAP1 AGAP1 Q9UPQ3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie 163 403 81 81 0
AGAP2 AGAP2 Q99490 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie 133 754 81 81 0
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
AHSA1 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 46 146 17 17 0
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
AP1B1 AP1B1 Q10567 AP-1 complex subunit beta-1 chr22 Not Cancer Driver No 1 hippie 114 119 10 10 1
AP1G1_ENST00000569748 AP1G1 O43747 AP-1 complex subunit gamma-1 chr16 Not Cancer Driver No 1 hippie 111 144 22 22 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 Not Cancer Driver No 1 hippie 126 316 31 31 1
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 Not Cancer Driver No 1 hippie 138 404 59 59 0
AP3S2 AP3S2 P59780 AP-3 complex subunit sigma-2 chr15 Not Cancer Driver No 1 hippie 21 0 0 0 0
AP4E1 AP4E1 Q9UPM8 AP-4 complex subunit epsilon-1 chr15 Not Cancer Driver No 1 hippie 130 148 28 28 2
AP4M1_ENST00000421755 AP4M1 O00189 AP-4 complex subunit mu-1 chr7 Not Cancer Driver No 1 hippie 63 64 7 7 0
ARF1_ENST00000272102 ARF1 P84077 ADP-ribosylation factor 1 chr1 Not Cancer Driver No 6 intact, hippie 30 4 2 2 2
ARF3 ARF3 P61204 ADP-ribosylation factor 3 chr12 Not Cancer Driver No 1 hippie, biogrid 17 4 1 1 0
ARF4 ARF4 P18085 ADP-ribosylation factor 4 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 17 0 0 0 0
ARF5 ARF5 P84085 ADP-ribosylation factor 5 chr7 Not Cancer Driver No 2 hippie, biogrid 22 11 2 2 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 18 5 0 0 0
ARFGAP1_ENST00000370283 ARFGAP1 Q8N6T3 ADP-ribosylation factor GTPase-activating protein 1 chr20 Not Cancer Driver No 2 hippie, biogrid 60 264 37 37 0
ARFGAP2 ARFGAP2 Q8N6H7 ADP-ribosylation factor GTPase-activating protein 2 chr11 Not Cancer Driver No 2 hippie, biogrid 62 345 40 40 0
ARFGAP3 ARFGAP3 Q9NP61 ADP-ribosylation factor GTPase-activating protein 3 chr22 Not Cancer Driver No 1 hippie, biogrid 53 321 38 38 0
ARFIP1 ARFIP1 P53367 Arfaptin-1 chr4 Not Cancer Driver No 2 intact, hippie 43 145 19 19 0
ARFIP2_ENST00000254584 ARFIP2 P53365 Arfaptin-2 chr11 Not Cancer Driver No 1 hippie 37 144 15 15 0
ARHGAP21 ARHGAP21 Q5T5U3 Rho GTPase-activating protein 21 chr10 Not Cancer Driver No 1 hippie 242 1612 204 204 0
ARHGAP31 ARHGAP31 Q2M1Z3 Rho GTPase-activating protein 31 chr3 Not Cancer Driver No 1 hippie, biogrid 272 1170 226 226 0
ARHGAP36 ARHGAP36 Q6ZRI8 Rho GTPase-activating protein 36 chrX Not Cancer Driver No 1 hippie, biogrid 194 132 61 61 0
ARIH2 ARIH2 O95376 E3 ubiquitin-protein ligase ARIH2 chr3 Not Cancer Driver No 1 biogrid 64 85 11 11 0
ASAP1 ASAP1 Q9ULH1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 chr8 Not Cancer Driver No 1 hippie 183 584 108 108 0
ASAP2 ASAP2 O43150 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 chr2 Not Cancer Driver No 1 hippie 141 453 63 63 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 Not Cancer Driver No 1 intact, hippie 65 451 58 58 0
B3GAT1_ENST00000312527 B3GAT1 Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 85 93 32 32 0
B3GNT2 B3GNT2 Q9NY97 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 chr2 Not Cancer Driver No 1 biogrid 51 22 6 6 0
B4GALT1 B4GALT1 P15291 Beta-1,4-galactosyltransferase 1 chr9 Not Cancer Driver No 1 biogrid 38 129 13 13 0
B4GALT3_ENST00000367998 B4GALT3 O60512 Beta-1,4-galactosyltransferase 3 chr1 Not Cancer Driver No 1 biogrid 56 171 27 27 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 biogrid 29 195 9 9 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
C11orf52 C11orf52 Q96A22 Uncharacterized protein C11orf52 chr11 Not Cancer Driver No 1 hippie, biogrid 15 108 12 12 0
CADPS CADPS Q9ULU8 Calcium-dependent secretion activator 1 chr3 Not Cancer Driver No 1 hippie 298 336 71 71 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 hippie 42 212 19 19 0
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 biogrid 161 88 7 7 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 biogrid 115 512 56 56 4
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 hippie, biogrid 71 95 12 12 0
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 Not Cancer Driver No 1 hippie, biogrid 66 5 1 1 0
CDC7 CDC7 O00311 Cell division cycle 7-related protein kinase chr1 Not Cancer Driver No 1 intact 72 185 24 24 0
CDC73 CDC73 Q6P1J9 Parafibromin chr1 Census, Compendium Yes 1 hippie 110 210 39 39 2
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CHCHD10_ENST00000484558 CHCHD10 Q8WYQ3 Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial chr22 Not Cancer Driver No 1 hippie 8 97 4 4 4
CHCHD2 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 Not Cancer Driver No 1 hippie 24 114 21 21 1
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CHRM3_ENST00000615928 CHRM3 P20309 Muscarinic acetylcholine receptor M3 chr1 Not Cancer Driver No 1 hippie 182 136 42 42 0
CKAP4 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 hippie, biogrid 73 409 55 55 0
COPB1_ENST00000439561 COPB1 P53618 Coatomer subunit beta chr11 Not Cancer Driver No 1 hippie 110 95 10 10 1
COPE_ENST00000262812 COPE O14579 Coatomer subunit epsilon chr19 Not Cancer Driver No 1 hippie 29 47 6 6 0
COPG1 COPG1 Q9Y678 Coatomer subunit gamma-1 chr3 Not Cancer Driver No 1 hippie 108 107 13 13 0
COQ2_ENST00000647002 COQ2 Q96H96 4-hydroxybenzoate polyprenyltransferase, mitochondrial chr4 Not Cancer Driver No 1 intact, hippie, biogrid 23 25 0 0 17
COQ7_ENST00000568985 COQ7 Q99807 5-demethoxyubiquinone hydroxylase, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 27 5 1 1 1
COQ9 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 hippie 43 111 13 13 0
COX15 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 1 intact, hippie, biogrid 48 0 0 0 2
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 51 98 19 19 0
CYTH1_ENST00000446868 CYTH1 Q15438 Cytohesin-1 chr17 Not Cancer Driver No 1 hippie 59 93 15 15 0
CYTH2_ENST00000641098 CYTH2 Q99418 Cytohesin-2 chr19 Not Cancer Driver No 1 hippie 55 93 12 12 0
DENND1A DENND1A Q8TEH3 DENN domain-containing protein 1A chr9 Not Cancer Driver No 1 hippie 117 589 76 76 0
DENND1B DENND1B Q6P3S1 DENN domain-containing protein 1B chr1 Not Cancer Driver No 1 hippie 69 299 19 19 0
DEPDC5_ENST00000382112 DEPDC5 O75140 GATOR complex protein DEPDC5 chr22 Not Cancer Driver No 1 biogrid 226 575 91 91 7
DIRAS3_ENST00000646789 DIRAS3 O95661 GTP-binding protein Di-Ras3 chr1 Not Cancer Driver No 1 hippie, biogrid 38 21 3 3 0
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 67 17 0 0 10
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 Not Cancer Driver No 1 hippie, biogrid 67 212 23 23 7
DPF2_ENST00000528416 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 Not Cancer Driver No 1 hippie 67 179 30 30 5
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 Not Cancer Driver No 1 hippie 84 0 0 0 0
EEF1G EEF1G P26641 Elongation factor 1-gamma chr11 Not Cancer Driver No 1 hippie, biogrid 44 66 5 5 0
EIF2B1 EIF2B1 Q14232 Translation initiation factor eIF-2B subunit alpha chr12 Not Cancer Driver No 1 hippie, biogrid 33 0 0 0 2
ELOVL5_ENST00000304434 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 Not Cancer Driver No 1 hippie, biogrid 34 25 4 4 2
EMD EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie, biogrid 42 160 28 28 4
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 intact 51 21 2 2 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
ERGIC1 ERGIC1 Q969X5 Endoplasmic reticulum-Golgi intermediate compartment protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 38 26 2 2 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ETF1 ETF1 P62495 Eukaryotic peptide chain release factor subunit 1 chr5 Not Cancer Driver No 1 intact 60 28 11 11 0
ETFA ETFA P13804 Electron transfer flavoprotein subunit alpha, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 30 34 2 2 3
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 biogrid 120 284 44 44 11
FAM136A FAM136A Q96C01 Protein FAM136A chr2 Not Cancer Driver No 1 intact, hippie 17 13 1 1 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 Not Cancer Driver No 1 intact, hippie 68 120 4 4 0
FGD5 FGD5 Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 chr3 Compendium Yes 1 intact, hippie, biogrid 275 915 180 180 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GALE GALE Q14376 UDP-glucose 4-epimerase chr1 Not Cancer Driver No 1 hippie, biogrid 32 24 2 2 16
GCNT2_ENST00000379597 GCNT2 Q8N0V5 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase chr6 Not Cancer Driver No 1 biogrid 40 3 0 0 0
GGA1 GGA1 Q9UJY5 ADP-ribosylation factor-binding protein GGA1 chr22 Not Cancer Driver No 1 hippie 75 385 33 33 0
GGA2 GGA2 Q9UJY4 ADP-ribosylation factor-binding protein GGA2 chr16 Not Cancer Driver No 1 hippie 84 240 37 37 0
GGA3 GGA3 Q9NZ52 ADP-ribosylation factor-binding protein GGA3 chr17 Not Cancer Driver No 1 hippie 73 419 41 41 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie, biogrid 86 110 26 26 50
GJD3 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 5 79 0 0 0
GLRX5 GLRX5 Q86SX6 Glutaredoxin-related protein 5, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 7 23 0 0 2
GOSR2_ENST00000640051 GOSR2 O14653 Golgi SNAP receptor complex member 2 chr17 Not Cancer Driver No 1 hippie 25 103 17 17 1
GOT1 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 Not Cancer Driver No 1 intact 56 35 5 5 0
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 Not Cancer Driver No 1 hippie 108 83 7 7 0
GRK5 GRK5 P34947 G protein-coupled receptor kinase 5 chr10 Not Cancer Driver No 1 hippie 77 103 18 18 0
HDAC8 HDAC8 Q9BY41 Histone deacetylase 8 chrX Not Cancer Driver No 1 biogrid 54 32 4 4 4
HERC1 HERC1 Q15751 Probable E3 ubiquitin-protein ligase HERC1 chr15 Not Cancer Driver No 1 hippie 487 1344 129 129 1
HOOK1 HOOK1 Q9UJC3 Protein Hook homolog 1 chr1 Not Cancer Driver No 1 hippie 97 427 59 59 0
HOOK2 HOOK2 Q96ED9 Protein Hook homolog 2 chr19 Not Cancer Driver No 1 intact 94 487 62 62 0
HSD17B11 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 Not Cancer Driver No 1 hippie, biogrid 28 3 0 0 0
HSD3B7 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 Not Cancer Driver No 1 hippie, biogrid 43 27 5 5 2
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 biogrid 100 254 43 43 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 Not Cancer Driver No 1 hippie 105 44 8 8 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 biogrid 183 265 37 37 6
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 Not Cancer Driver No 1 hippie, biogrid 70 6 1 1 0
INSR INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 hippie 190 280 57 57 64
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 254 97 27 27 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KDELR1 KDELR1 P24390 ER lumen protein-retaining receptor 1 chr19 Not Cancer Driver No 1 intact, hippie 32 0 0 0 0
KHSRP KHSRP Q92945 Far upstream element-binding protein 2 chr19 Not Cancer Driver No 1 biogrid 84 684 81 81 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 3 intact, hippie, biogrid 788 7 2 2 27
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie, biogrid 43 55 7 7 1
LAMP3 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 67 222 38 38 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LDHAL6A LDHAL6A Q6ZMR3 L-lactate dehydrogenase A-like 6A chr11 Not Cancer Driver No 1 hippie, biogrid 47 16 4 4 0
LDHAL6B LDHAL6B Q9BYZ2 L-lactate dehydrogenase A-like 6B chr15 Not Cancer Driver No 1 hippie, biogrid 54 17 2 2 0
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie, biogrid 40 9 0 0 0
LDHB_ENST00000350669 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie, biogrid 47 15 2 2 11
LDHC LDHC P07864 L-lactate dehydrogenase C chain chr11 Not Cancer Driver No 1 hippie, biogrid 61 0 0 0 0
LNPK_ENST00000272748 LNPK Q9C0E8 Endoplasmic reticulum junction formation protein lunapark chr2 Not Cancer Driver No 1 hippie 62 257 43 43 0
LRIF1 LRIF1 Q5T3J3 Ligand-dependent nuclear receptor-interacting factor 1 chr1 Not Cancer Driver No 1 hippie 116 520 74 74 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 95 84 12 12 0
LYRM2 LYRM2 Q9NU23 LYR motif-containing protein 2 chr6 Not Cancer Driver No 1 intact, hippie 5 30 4 4 0
LYRM7 LYRM7 Q5U5X0 Complex III assembly factor LYRM7 chr5 Not Cancer Driver No 1 intact, hippie 5 28 1 1 1
MAIP1 MAIP1 Q8WWC4 m-AAA protease-interacting protein 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 28 12 0 0 0
MAN1A1 MAN1A1 P33908 Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA chr6 Not Cancer Driver No 1 biogrid 118 134 23 23 0
MAN1B1 MAN1B1 Q9UKM7 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase chr9 Not Cancer Driver No 1 biogrid 74 172 22 22 2
MAN2A1 MAN2A1 Q16706 Alpha-mannosidase 2 chr5 Not Cancer Driver No 1 biogrid 165 83 9 9 0
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 14 328 14 14 0
MDM4 MDM4 O15151 Protein Mdm4 chr1 Census, Compendium Yes 1 hippie 57 202 26 26 1
METTL7A_ENST00000332160 METTL7A Q9H8H3 Putative methyltransferase-like protein 7A chr12 Not Cancer Driver No 1 hippie, biogrid 31 0 0 0 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 45 145 16 16 0
MMS19 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 Not Cancer Driver No 1 hippie 73 11 0 0 0
MTF2 MTF2 Q9Y483 Metal-response element-binding transcription factor 2 chr1 Not Cancer Driver No 1 biogrid 70 225 28 28 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 Census, Compendium Yes 1 biogrid 352 2347 340 340 0
NEDD8-MDP1 NEDD8-MDP1 E9PL57 NEDD8-MDP1 readthrough (Fragment) chr14 Not Cancer Driver No 1 biogrid 28 55 13 13 0
NOA1 NOA1 Q8NC60 Nitric oxide-associated protein 1 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 74 225 25 25 0
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 29 249 22 22 0
NPRL2 NPRL2 Q8WTW4 GATOR complex protein NPRL2 chr3 Compendium Yes 1 biogrid 37 10 3 3 1
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 Not Cancer Driver No 1 hippie 107 58 27 27 0
PAICS_ENST00000512576 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 Not Cancer Driver No 1 hippie, biogrid 23 35 3 3 0
PANX1 PANX1 Q96RD7 Pannexin-1 chr11 Not Cancer Driver No 1 hippie, biogrid 54 45 7 7 2
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 11 30 0 0 5
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PEX3 PEX3 P56589 Peroxisomal biogenesis factor 3 chr6 Not Cancer Driver No 1 hippie, biogrid 31 24 0 0 2
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 Not Cancer Driver No 1 hippie 50 49 3 3 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PIP5K1A PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 Not Cancer Driver No 1 hippie 74 216 29 29 0
PLD1 PLD1 Q13393 Phospholipase D1 chr3 Not Cancer Driver No 2 hippie, biogrid 181 133 32 32 1
PLD2 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 1 hippie 107 97 8 8 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHA8 PLEKHA8 Q96JA3 Pleckstrin homology domain-containing family A member 8 chr7 Not Cancer Driver No 1 hippie 57 128 22 22 0
PLEKHG4 PLEKHG4 Q58EX7 Puratrophin-1 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 132 295 35 35 0
PLEKHG6_ENST00000011684 PLEKHG6 Q3KR16 Pleckstrin homology domain-containing family G member 6 chr12 Not Cancer Driver No 1 hippie, biogrid 103 471 65 65 0
PLIN2 PLIN2 Q99541 Perilipin-2 chr9 Not Cancer Driver No 1 hippie 43 126 14 14 0
POLE3 POLE3 Q9NRF9 DNA polymerase epsilon subunit 3 chr9 Not Cancer Driver No 1 biogrid 11 117 9 9 0
PRKACB_ENST00000370689 PRKACB P22694 cAMP-dependent protein kinase catalytic subunit beta chr1 Not Cancer Driver No 1 hippie, biogrid 50 26 6 6 4
PRNP PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 36 115 7 7 18
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie 49 140 25 25 0
PTPN18 PTPN18 Q99952 Tyrosine-protein phosphatase non-receptor type 18 chr2 Not Cancer Driver No 1 hippie 51 138 8 8 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 hippie 62 341 24 24 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 2 hippie, biogrid 31 43 4 4 0
RAB11B RAB11B Q15907 Ras-related protein Rab-11B chr19 Not Cancer Driver No 1 hippie, biogrid 26 39 3 3 2
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 Not Cancer Driver No 1 hippie, biogrid 16 38 2 2 0
RAB1B RAB1B Q9H0U4 Ras-related protein Rab-1B chr11 Not Cancer Driver No 2 hippie, biogrid 24 40 3 3 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 3 hippie, biogrid 22 58 4 4 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
RAB3B RAB3B P20337 Ras-related protein Rab-3B chr1 Not Cancer Driver No 1 hippie, biogrid 36 25 6 6 0
RAB4A RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie, biogrid 26 32 11 11 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie, biogrid 32 65 15 15 0
RAB5B RAB5B P61020 Ras-related protein Rab-5B chr12 Not Cancer Driver No 1 hippie, biogrid 23 43 5 5 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 3 hippie, biogrid 24 50 4 4 0
RAB6A_ENST00000336083 RAB6A P20340 Ras-related protein Rab-6A chr11 Not Cancer Driver No 1 hippie, biogrid 22 45 6 6 0
RAB6B RAB6B Q9NRW1 Ras-related protein Rab-6B chr3 Not Cancer Driver No 1 hippie, biogrid 39 42 5 5 0
RAB8A RAB8A P61006 Ras-related protein Rab-8A chr19 Not Cancer Driver No 1 hippie 37 26 3 3 0
RAB9A RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 1 hippie, biogrid 18 21 1 1 0
RABGEF1_ENST00000284957 RABGEF1 Q9UJ41 Rab5 GDP/GTP exchange factor chr7 Not Cancer Driver No 1 biogrid 73 175 35 35 0
RAD52 RAD52 P43351 DNA repair protein RAD52 homolog chr12 Not Cancer Driver No 1 intact, hippie 41 251 30 30 0
RALA RALA P11233 Ras-related protein Ral-A chr7 Not Cancer Driver No 1 hippie 34 34 3 3 5
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie, biogrid 52 19 2 2 0
RICTOR_ENST00000357387 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 Not Cancer Driver No 1 biogrid 212 366 50 50 0
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie, biogrid 50 69 3 3 0
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 53 26 4 4 0
SAR1A_ENST00000373238 SAR1A Q9NR31 GTP-binding protein SAR1a chr10 Not Cancer Driver No 2 hippie, biogrid 23 4 0 0 0
SCYL1 SCYL1 Q96KG9 N-terminal kinase-like protein chr11 Not Cancer Driver No 1 hippie 85 312 32 32 0
SEC23B SEC23B Q15437 Protein transport protein Sec23B chr20 Not Cancer Driver No 1 biogrid 105 82 4 4 7
SEC23IP SEC23IP Q9Y6Y8 SEC23-interacting protein chr10 Not Cancer Driver No 1 biogrid 112 371 40 40 0
SEC24A SEC24A O95486 Protein transport protein Sec24A chr5 Not Cancer Driver No 1 biogrid 113 407 49 49 0
SEC24C SEC24C P53992 Protein transport protein Sec24C chr10 Not Cancer Driver No 1 biogrid 121 402 38 38 0
SEC31A_ENST00000355196 SEC31A O94979 Protein transport protein Sec31A chr4 Not Cancer Driver No 1 biogrid 139 519 58 58 0
SEC61B SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 hippie, biogrid 11 60 7 7 0
SEC62 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 41 211 23 23 0
SEPT5 SEPTIN5 Q99719 Septin-5 chr22 Not Cancer Driver No 1 intact 50 76 5 5 0
SLC30A5 SLC30A5 Q8TAD4 Zinc transporter 5 chr5 Not Cancer Driver No 1 biogrid 58 33 0 0 0
SLC33A1_ENST00000643144 SLC33A1 O00400 Acetyl-coenzyme A transporter 1 chr3 Not Cancer Driver No 1 biogrid 64 54 8 8 2
SLC39A3 SLC39A3 Q9BRY0 Zinc transporter ZIP3 chr19 Not Cancer Driver No 1 biogrid 41 0 0 0 0
SLC39A7 SLC39A7 Q92504 Zinc transporter SLC39A7 chr6 Not Cancer Driver No 1 biogrid 47 192 17 17 0
SNAP25 SNAP25 P60880 Synaptosomal-associated protein 25 chr20 Not Cancer Driver No 1 hippie 61 176 49 49 1
SOAT1 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 73 49 4 4 0
SPAG9 SPAG9 O60271 C-Jun-amino-terminal kinase-interacting protein 4 chr17 Not Cancer Driver No 1 hippie 128 841 81 81 0
SPATA20_ENST00000356488 SPATA20 Q8TB22 Spermatogenesis-associated protein 20 chr17 Not Cancer Driver No 1 hippie 101 162 19 19 0
SPRYD4 SPRYD4 Q8WW59 SPRY domain-containing protein 4 chr12 Not Cancer Driver No 1 hippie 16 1 0 0 0
SSR1 SSR1 P43307 Translocon-associated protein subunit alpha chr6 Not Cancer Driver No 1 hippie, biogrid 26 114 10 10 0
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 Not Cancer Driver No 1 hippie, biogrid 70 387 45 45 13
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 1 intact, hippie 70 231 30 30 0
STX4 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 50 152 20 20 0
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 29 164 14 14 0
TBL1XR1 TBL1XR1 Q9BZK7 F-box-like/WD repeat-containing protein TBL1XR1 chr3 Census, Compendium Yes 1 biogrid 82 136 19 19 4
TET2 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 Census, Compendium Yes 1 hippie 191 1663 176 176 1
TMED10 TMED10 P49755 Transmembrane emp24 domain-containing protein 10 chr14 Not Cancer Driver No 1 hippie 24 15 3 3 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 Not Cancer Driver No 1 intact, hippie 24 25 4 4 0
TMEM106A TMEM106A Q96A25 Transmembrane protein 106A chr17 Not Cancer Driver No 1 intact, hippie 26 9 1 1 0
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie, biogrid 78 412 52 52 0
TRAPPC12 TRAPPC12 Q8WVT3 Trafficking protein particle complex subunit 12 chr2 Not Cancer Driver No 1 biogrid 88 318 31 31 0
TRAPPC13_ENST00000399438 TRAPPC13 A5PLN9 Trafficking protein particle complex subunit 13 chr5 Not Cancer Driver No 1 biogrid 34 18 0 0 0
TRAPPC2L_ENST00000301021 TRAPPC2L Q9UL33 Trafficking protein particle complex subunit 2-like protein chr16 Not Cancer Driver No 1 biogrid 21 0 0 0 1
TRPV2 TRPV2 Q9Y5S1 Transient receptor potential cation channel subfamily V member 2 chr17 Not Cancer Driver No 1 intact, hippie 105 175 23 23 0
TSC1 TSC1 Q92574 Hamartin chr9 Census, Compendium Yes 1 biogrid 135 732 78 78 11
TSC2 TSC2 P49815 Tuberin chr16 Census, Compendium Yes 1 biogrid 192 563 50 50 53
TUFM TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 51 50 3 3 1
UBD UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 31 8 1 1 0
UBE2J1 UBE2J1 Q9Y385 Ubiquitin-conjugating enzyme E2 J1 chr6 Not Cancer Driver No 1 biogrid 33 158 20 20 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 biogrid 30 32 6 6 0
UNK UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 79 511 46 46 0
USP39 USP39 Q53GS9 U4/U6.U5 tri-snRNP-associated protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 58 128 10 10 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 188 110 28 28 0
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 38 36 4 4 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VPS51 VPS51 Q9UID3 Vacuolar protein sorting-associated protein 51 homolog chr11 Not Cancer Driver No 1 biogrid 75 150 11 11 1
WBP11 WBP11 Q9Y2W2 WW domain-binding protein 11 chr12 Not Cancer Driver No 1 hippie, biogrid 86 606 79 79 0
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 79 108 9 9 3
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
ZC3H7A_ENST00000355758 ZC3H7A Q8IWR0 Zinc finger CCCH domain-containing protein 7A chr16 Not Cancer Driver No 1 hippie 91 224 23 23 0
ZFPL1 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie, biogrid 40 127 16 16 0