Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACTC1 | ACTC1 | P68032 | Actin, alpha cardiac muscle 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 114 | 48 | 19 | 19 | 11 |
ACTL6A | ACTL6A | O96019 | Actin-like protein 6A | chr3 | Not Cancer Driver | No | 1 | hippie | 61 | 74 | 15 | 15 | 0 |
ACTR6 | ACTR6 | Q9GZN1 | Actin-related protein 6 | chr12 | Not Cancer Driver | No | 1 | hippie | 48 | 17 | 4 | 4 | 0 |
AHCYL1 | AHCYL1 | O43865 | S-adenosylhomocysteine hydrolase-like protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 108 | 10 | 10 | 0 |
AHCYL2 | AHCYL2 | Q96HN2 | Adenosylhomocysteinase 3 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 208 | 23 | 23 | 0 |
ANP32A | ANP32A | P39687 | Acidic leucine-rich nuclear phosphoprotein 32 family member A | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 165 | 21 | 21 | 0 |
ATG7 | ATG7 | O95352 | Ubiquitin-like modifier-activating enzyme ATG7 | chr3 | Compendium | Yes | 1 | hippie | 77 | 53 | 8 | 8 | 6 |
ATP6V1C1_ENST00000518738 | ATP6V1C1 | P21283 | V-type proton ATPase subunit C 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 54 | 17 | 3 | 3 | 0 |
BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
BRD7_ENST00000394688 | BRD7 | Q9NPI1 | Bromodomain-containing protein 7 | chr16 | Compendium | Yes | 2 | hippie, biogrid | 82 | 482 | 57 | 57 | 0 |
BRD8 | BRD8 | Q9H0E9 | Bromodomain-containing protein 8 | chr5 | Not Cancer Driver | No | 1 | hippie | 189 | 934 | 147 | 147 | 0 |
CBX3_ENST00000396386 | CBX3 | Q13185 | Chromobox protein homolog 3 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 119 | 18 | 18 | 0 |
DDX23 | DDX23 | Q9BUQ8 | Probable ATP-dependent RNA helicase DDX23 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 121 | 426 | 71 | 71 | 0 |
DMAP1_ENST00000315913 | DMAP1 | Q9NPF5 | DNA methyltransferase 1-associated protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 269 | 28 | 28 | 0 |
DNAJB6 | DNAJB6 | O75190 | DnaJ homolog subfamily B member 6 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 198 | 17 | 17 | 3 |
DNAJC9 | DNAJC9 | Q8WXX5 | DnaJ homolog subfamily C member 9 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 126 | 15 | 15 | 0 |
EFTUD2 | EFTUD2 | Q15029 | 116 kDa U5 small nuclear ribonucleoprotein component | chr17 | Compendium | Yes | 1 | hippie | 132 | 179 | 30 | 30 | 3 |
EP400 | EP400 | Q96L91 | E1A-binding protein p400 | chr12 | Not Cancer Driver | No | 1 | hippie | 397 | 2064 | 234 | 234 | 0 |
EPC1 | EPC1 | Q9H2F5 | Enhancer of polycomb homolog 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 104 | 515 | 68 | 68 | 0 |
EPC2 | EPC2 | Q52LR7 | Enhancer of polycomb homolog 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 95 | 583 | 67 | 67 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
EWSR1_ENST00000397938 | EWSR1 | Q01844 | RNA-binding protein EWS | chr22 | Census, Compendium | Yes | 1 | hippie | 94 | 646 | 93 | 93 | 0 |
FBXO7 | FBXO7 | Q9Y3I1 | F-box only protein 7 | chr22 | Not Cancer Driver | No | 1 | hippie | 75 | 243 | 38 | 38 | 1 |
FOS | FOS | P01100 | Protein c-Fos | chr14 | Not Cancer Driver | No | 1 | hippie | 45 | 245 | 33 | 33 | 0 |
FYTTD1 | FYTTD1 | Q96QD9 | UAP56-interacting factor | chr3 | Not Cancer Driver | No | 1 | hippie | 51 | 281 | 48 | 48 | 0 |
G3BP1 | G3BP1 | Q13283 | Ras GTPase-activating protein-binding protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 85 | 352 | 65 | 65 | 0 |
HSCB | HSCB | Q8IWL3 | Iron-sulfur cluster co-chaperone protein HscB | chr22 | Not Cancer Driver | No | 1 | hippie | 36 | 25 | 6 | 6 | 0 |
HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | hippie | 149 | 251 | 52 | 52 | 0 |
IMMP2L_ENST00000452895 | IMMP2L | Q96T52 | Mitochondrial inner membrane protease subunit 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 36 | 29 | 7 | 7 | 0 |
ING3 | ING3 | Q9NXR8 | Inhibitor of growth protein 3 | chr7 | Not Cancer Driver | No | 1 | hippie | 44 | 292 | 32 | 32 | 1 |
IPO9 | IPO9 | Q96P70 | Importin-9 | chr1 | Not Cancer Driver | No | 1 | hippie | 145 | 102 | 22 | 22 | 0 |
KAT5_ENST00000377046 | KAT5 | Q92993 | Histone acetyltransferase KAT5 | chr11 | Not Cancer Driver | No | 1 | hippie | 65 | 173 | 21 | 21 | 3 |
KIF23 | KIF23 | Q02241 | Kinesin-like protein KIF23 | chr15 | Not Cancer Driver | No | 1 | hippie | 102 | 559 | 62 | 62 | 0 |
KPNA1 | KPNA1 | P52294 | Importin subunit alpha-5 | chr3 | Not Cancer Driver | No | 2 | hippie, biogrid | 65 | 121 | 18 | 18 | 0 |
KPNA5 | KPNA5 | O15131 | Importin subunit alpha-6 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 133 | 13 | 13 | 0 |
KPNA6 | KPNA6 | O60684 | Importin subunit alpha-7 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 97 | 17 | 17 | 0 |
LMNA | LMNA | P02545 | Prelamin-A/C | chr1 | Census | Yes | 1 | hippie | 68 | 544 | 49 | 49 | 131 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 519 | 90 | 17 | 17 | 23 |
MEPCE | MEPCE | Q7L2J0 | 7SK snRNA methylphosphate capping enzyme | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 446 | 42 | 42 | 0 |
MGMT | MGMT | B4DEE8 | Methylated-DNA--protein-cysteine methyltransferase | chr10 | Census | Yes | 1 | hippie | 43 | 40 | 15 | 15 | 0 |
MORF4L1 | MORF4L1 | Q9UBU8 | Mortality factor 4-like protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 43 | 163 | 17 | 17 | 0 |
MORF4L2_ENST00000433176 | MORF4L2 | Q15014 | Mortality factor 4-like protein 2 | chrX | Not Cancer Driver | No | 1 | hippie | 44 | 136 | 21 | 21 | 0 |
MRGBP | MRGBP | Q9NV56 | MRG/MORF4L-binding protein | chr20 | Not Cancer Driver | No | 1 | hippie | 27 | 147 | 23 | 23 | 0 |
MSH2 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | Census | Yes | 1 | hippie | 92 | 37 | 4 | 4 | 70 |
MSH6 | MSH6 | P52701 | DNA mismatch repair protein Msh6 | chr2 | Census | Yes | 1 | hippie | 154 | 386 | 41 | 41 | 6 |
NAA40 | NAA40 | Q86UY6 | N-alpha-acetyltransferase 40 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 30 | 3 | 3 | 0 |
NAP1L1 | NAP1L1 | P55209 | Nucleosome assembly protein 1-like 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 47 | 207 | 31 | 31 | 0 |
NIFK | NIFK | Q9BYG3 | MKI67 FHA domain-interacting nucleolar phosphoprotein | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 148 | 15 | 15 | 0 |
NOP56 | NOP56 | O00567 | Nucleolar protein 56 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 191 | 34 | 34 | 0 |
NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
NR4A2_ENST00000409572 | NR4A2 | P43354 | Nuclear receptor subfamily 4 group A member 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 110 | 261 | 38 | 38 | 0 |
NSD2_ENST00000382892 | NSD2 | O96028 | Histone-lysine N-methyltransferase NSD2 | chr4 | Census, Compendium | Yes | 1 | hippie | 191 | 552 | 76 | 76 | 0 |
NXF1_ENST00000294172 | NXF1 | Q9UBU9 | Nuclear RNA export factor 1 | chr11 | Compendium | Yes | 1 | hippie | 100 | 163 | 32 | 32 | 0 |
OTUB1_ENST00000428192 | OTUB1 | Q96FW1 | Ubiquitin thioesterase OTUB1 | chr11 | Not Cancer Driver | No | 1 | hippie | 31 | 33 | 2 | 2 | 0 |
P2RY6_ENST00000540342 | P2RY6 | Q15077 | P2Y purinoceptor 6 | chr11 | Not Cancer Driver | No | 1 | hippie | 50 | 10 | 5 | 5 | 0 |
PAPPA | PAPPA | Q13219 | Pappalysin-1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 370 | 239 | 37 | 37 | 0 |
PARD3 | PARD3 | Q8TEW0 | Partitioning defective 3 homolog | chr10 | Not Cancer Driver | No | 1 | hippie | 200 | 1144 | 170 | 170 | 2 |
PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 119 | 320 | 34 | 34 | 0 |
PBRM1_ENST00000296302 | PBRM1 | Q86U86 | Protein polybromo-1 | chr3 | Census, Compendium | Yes | 1 | hippie, biogrid | 209 | 703 | 77 | 77 | 0 |
PHLPP1 | PHLPP1 | O60346 | PH domain leucine-rich repeat-containing protein phosphatase 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 134 | 744 | 29 | 29 | 0 |
PLEKHH1 | PLEKHH1 | Q9ULM0 | Pleckstrin homology domain-containing family H member 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 131 | 575 | 62 | 62 | 0 |
PMAIP1 | PMAIP1 | Q13794 | Phorbol-12-myristate-13-acetate-induced protein 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 2 | 23 | 1 | 1 | 0 |
PRC1 | PRC1 | O43663 | Protein regulator of cytokinesis 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 63 | 235 | 26 | 26 | 0 |
PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | Not Cancer Driver | No | 1 | hippie | 538 | 421 | 61 | 61 | 2 |
PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | Census, Compendium | Yes | 1 | hippie | 505 | 76 | 4 | 4 | 41 |
PTPN2 | PTPN2 | P17706 | Tyrosine-protein phosphatase non-receptor type 2 | chr18 | Not Cancer Driver | No | 1 | hippie | 57 | 120 | 14 | 14 | 0 |
RAD50 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | Not Cancer Driver | No | 1 | hippie | 157 | 730 | 84 | 84 | 0 |
RDX_ENST00000343115 | RDX | P35241 | Radixin | chr11 | Not Cancer Driver | No | 1 | hippie | 71 | 297 | 37 | 37 | 1 |
RNASEH2B | RNASEH2B | Q5TBB1 | Ribonuclease H2 subunit B | chr13 | Not Cancer Driver | No | 1 | hippie | 34 | 84 | 9 | 9 | 14 |
RNF123 | RNF123 | Q5XPI4 | E3 ubiquitin-protein ligase RNF123 | chr3 | Not Cancer Driver | No | 1 | hippie | 167 | 220 | 28 | 28 | 0 |
RPL31_ENST00000264258 | RPL31 | P62899 | 60S ribosomal protein L31 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 69 | 14 | 14 | 0 |
RPS2 | RPS2 | P15880 | 40S ribosomal protein S2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 85 | 14 | 14 | 0 |
RPS24_ENST00000613865 | RPS24 | P62847 | 40S ribosomal protein S24 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 88 | 10 | 10 | 0 |
RUVBL1 | RUVBL1 | Q9Y265 | RuvB-like 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 54 | 67 | 7 | 7 | 0 |
RUVBL2 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 62 | 100 | 13 | 13 | 0 |
SMAD2_ENST00000402690 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | Census, Compendium | Yes | 1 | hippie | 79 | 137 | 12 | 12 | 0 |
SNX2 | SNX2 | O60749 | Sorting nexin-2 | chr5 | Not Cancer Driver | No | 1 | hippie | 45 | 218 | 18 | 18 | 0 |
SNX6 | SNX6 | Q9UNH7 | Sorting nexin-6 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 85 | 7 | 7 | 0 |
SOX2 | SOX2 | P48431 | Transcription factor SOX-2 | chr3 | Census | Yes | 1 | hippie | 39 | 312 | 39 | 39 | 0 |
SRCAP | SRCAP | Q6ZRS2 | Helicase SRCAP | chr16 | Not Cancer Driver | No | 1 | hippie | 438 | 2534 | 340 | 340 | 0 |
SSRP1 | SSRP1 | Q08945 | FACT complex subunit SSRP1 | chr11 | Not Cancer Driver | No | 1 | hippie | 92 | 308 | 35 | 35 | 0 |
SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
SUPT16H | SUPT16H | Q9Y5B9 | FACT complex subunit SPT16 | chr14 | Not Cancer Driver | No | 1 | hippie | 147 | 301 | 44 | 44 | 0 |
TES | TES | Q9UGI8 | Testin | chr7 | Not Cancer Driver | No | 1 | hippie | 56 | 100 | 7 | 7 | 0 |
TPGS1 | TPGS1 | Q6ZTW0 | Tubulin polyglutamylase complex subunit 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 6 | 62 | 2 | 2 | 0 |
TPI1_ENST00000396705 | TPI1 | P60174 | Triosephosphate isomerase | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 15 | 2 | 2 | 7 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 430 | 41 | 41 | 0 |
TRRAP | TRRAP | Q9Y4A5 | Transformation/transcription domain-associated protein | chr7 | Census, Compendium | Yes | 1 | hippie | 554 | 402 | 59 | 59 | 8 |
UBA5 | UBA5 | Q9GZZ9 | Ubiquitin-like modifier-activating enzyme 5 | chr3 | Not Cancer Driver | No | 1 | hippie | 41 | 126 | 8 | 8 | 7 |
UCHL5 | UCHL5 | Q9Y5K5 | Ubiquitin carboxyl-terminal hydrolase isozyme L5 | chr1 | Not Cancer Driver | No | 1 | hippie | 33 | 41 | 7 | 7 | 0 |
UNK | UNK | Q9C0B0 | RING finger protein unkempt homolog | chr17 | Not Cancer Driver | No | 1 | hippie | 79 | 511 | 46 | 46 | 0 |
VPS35 | VPS35 | Q96QK1 | Vacuolar protein sorting-associated protein 35 | chr16 | Not Cancer Driver | No | 1 | hippie | 68 | 99 | 9 | 9 | 1 |
VPS72 | VPS72 | Q15906 | Vacuolar protein sorting-associated protein 72 homolog | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 329 | 37 | 37 | 0 |
XRCC5_ENST00000392132 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | Not Cancer Driver | No | 1 | hippie | 87 | 118 | 11 | 11 | 0 |
XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | Not Cancer Driver | No | 1 | hippie | 66 | 140 | 12 | 12 | 0 |
YEATS4 | YEATS4 | O95619 | YEATS domain-containing protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie | 23 | 17 | 1 | 1 | 0 |
ZDHHC5 | ZDHHC5 | Q9C0B5 | Palmitoyltransferase ZDHHC5 | chr11 | Not Cancer Driver | No | 1 | hippie | 89 | 462 | 63 | 63 | 0 |
ZNF330 | ZNF330 | Q9Y3S2 | Zinc finger protein 330 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 127 | 19 | 19 | 0 |
ZNHIT1 | ZNHIT1 | O43257 | Zinc finger HIT domain-containing protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 34 | 85 | 16 | 16 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|