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AMY1A ,AMY1A ,P0DUB6
  • Uniprot Accession= P0DUB6
  • Ensembl Transcript= ENST00000370083.8
  • Uniprot Name= AMY1A
  • Name= Alpha-amylase 1A
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 30
  • Number of Interaction partner in biogrid: 13
  • Number of Interaction partner in hippie: 99
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ABCA8 ABCA8 O94911 ABC-type organic anion transporter ABCA8 chr17 Not Cancer Driver No 1 hippie 290 91 20 20 0
ACTR8 ACTR8 Q9H981 Actin-related protein 8 chr3 Not Cancer Driver No 2 intact, hippie 61 239 21 21 0
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie 107 537 67 67 0
AKAP8 AKAP8 O43823 A-kinase anchor protein 8 chr19 Not Cancer Driver No 1 hippie 88 566 78 78 0
AKNAD1 AKNAD1 Q5T1N1 Protein AKNAD1 chr1 Not Cancer Driver No 1 hippie 134 690 111 111 0
AMY2B AMY2B P19961 Alpha-amylase 2B chr1 Not Cancer Driver No 1 hippie 140 32 11 11 0
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 biogrid 84 181 32 32 0
ARMCX3_ENST00000537169 ARMCX3 Q9UH62 Armadillo repeat-containing X-linked protein 3 chrX Not Cancer Driver No 1 hippie 39 77 7 7 0
ASCC2 ASCC2 Q9H1I8 Activating signal cointegrator 1 complex subunit 2 chr22 Not Cancer Driver No 1 hippie 87 326 34 34 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 Not Cancer Driver No 1 biogrid 168 341 64 64 0
B3GALNT1_ENST00000392779 B3GALNT1 O75752 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 chr3 Not Cancer Driver No 2 intact, hippie 51 0 0 0 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 Not Cancer Driver No 1 hippie 38 58 9 9 0
BTBD1 BTBD1 Q9H0C5 BTB/POZ domain-containing protein 1 chr15 Not Cancer Driver No 1 hippie 48 50 1 1 0
C10orf53_ENST00000374111 C10orf53 Q8N6V4 UPF0728 protein C10orf53 chr10 Not Cancer Driver No 1 hippie 12 0 0 0 0
CACUL1 CACUL1 Q86Y37 CDK2-associated and cullin domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie 35 128 6 6 0
CAMK1D CAMK1D Q8IU85 Calcium/calmodulin-dependent protein kinase type 1D chr10 Not Cancer Driver No 2 intact, hippie 90 42 14 14 0
CCDC174 CCDC174 Q6PII3 Coiled-coil domain-containing protein 174 chr3 Not Cancer Driver No 1 hippie 60 408 51 51 0
CCRL2_ENST00000399036 CCRL2 O00421 C-C chemokine receptor-like 2 chr3 Not Cancer Driver No 2 intact, hippie 44 20 5 5 0
CDC7 CDC7 O00311 Cell division cycle 7-related protein kinase chr1 Not Cancer Driver No 1 intact, hippie, biogrid 72 185 24 24 0
CDK2AP1 CDK2AP1 O14519 Cyclin-dependent kinase 2-associated protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 10 76 8 8 0
CDKL3 CDKL3 Q8IVW4 Cyclin-dependent kinase-like 3 chr5 Not Cancer Driver No 1 biogrid 68 278 40 40 0
CFB CFB P00751 Complement factor B chr6 Not Cancer Driver No 1 hippie 75 112 20 20 7
CMKLR1 CMKLR1 Q99788 Chemerin-like receptor 1 chr12 Not Cancer Driver No 1 hippie 107 24 13 13 0
COG2 COG2 Q14746 Conserved oligomeric Golgi complex subunit 2 chr1 Not Cancer Driver No 1 hippie 90 105 16 16 1
COMMD1 COMMD1 Q8N668 COMM domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie 21 17 0 0 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 hippie 61 84 13 13 0
DAZ2_ENST00000382424 DAZ2 Q13117 Deleted in azoospermia protein 2 chrY Not Cancer Driver No 1 hippie 1 72 0 0 0
DDX17_ENST00000640332 DDX17 Q92841 Probable ATP-dependent RNA helicase DDX17 chr22 Not Cancer Driver No 1 hippie 91 362 48 48 0
DNAH17 DNAH17 Q9UFH2 Dynein axonemal heavy chain 17 chr17 Not Cancer Driver No 1 hippie 725 175 31 31 3
DUSP4 DUSP4 Q13115 Dual specificity protein phosphatase 4 chr8 Not Cancer Driver No 1 intact, hippie 43 63 9 9 0
E2F6 E2F6 O75461 Transcription factor E2F6 chr2 Not Cancer Driver No 1 intact, hippie 20 105 10 10 0
ECE2 ECE2 P0DPD6 Endothelin-converting enzyme 2 chr3 Not Cancer Driver No 1 hippie 178 149 40 40 0
FAM24B_ENST00000368896 FAM24B Q8N5W8 Protein FAM24B chr10 Not Cancer Driver No 1 hippie 9 0 0 0 0
FKBP5 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 1 hippie 70 150 20 20 0
FNBP4 FNBP4 Q8N3X1 Formin-binding protein 4 chr11 Not Cancer Driver No 1 hippie 119 926 106 106 0
FNDC5_ENST00000640867 FNDC5 Q8NAU1 Fibronectin type III domain-containing protein 5 chr1 Not Cancer Driver No 1 hippie 17 74 8 8 0
FOXN4 FOXN4 Q96NZ1 Forkhead box protein N4 chr12 Not Cancer Driver No 1 intact, hippie 60 377 34 34 0
FRMD1 FRMD1 Q8N878 FERM domain-containing protein 1 chr6 Not Cancer Driver No 1 intact, hippie 82 259 36 36 0
GKN1 GKN1 A0A8I5KHR1 Gastrokine-1 chr2 Not Cancer Driver No 1 intact, hippie 37 50 7 7 0
GTF2B GTF2B Q00403 Transcription initiation factor IIB chr1 Not Cancer Driver No 2 intact, hippie 33 80 6 6 0
GYG1 GYG1 P46976 Glycogenin-1 chr3 Not Cancer Driver No 1 hippie 38 21 3 3 3
GYG2 GYG2 O15488 Glycogenin-2 chrX Not Cancer Driver No 1 hippie 70 217 28 28 0
GYS1 GYS1 P13807 Glycogen [starch] synthase, muscle chr19 Not Cancer Driver No 1 hippie 98 127 18 18 0
HBQ1 HBQ1 P09105 Hemoglobin subunit theta-1 chr16 Not Cancer Driver No 1 hippie 10 0 0 0 0
HINT2 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 1 hippie 10 29 2 2 0
HTN3_ENST00000526767 HTN3 P15516 Histatin-3 chr4 Not Cancer Driver No 1 hippie 10 13 3 3 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 Census, Compendium Yes 1 hippie 136 59 5 5 5
KLF15 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 Not Cancer Driver No 1 hippie 66 273 48 48 0
KLHL22 KLHL22 Q53GT1 Kelch-like protein 22 chr22 Not Cancer Driver No 1 hippie 90 50 8 8 0
LYPD6B_ENST00000409876 LYPD6B Q8NI32 Ly6/PLAUR domain-containing protein 6B chr2 Not Cancer Driver No 1 hippie 35 3 4 4 0
MAB21L1 MAB21L1 Q13394 Putative nucleotidyltransferase MAB21L1 chr13 Not Cancer Driver No 2 intact, hippie 94 0 0 0 0
MAGED2 MAGED2 Q9UNF1 Melanoma-associated antigen D2 chrX Not Cancer Driver No 1 hippie 99 326 53 53 1
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 Census Yes 1 biogrid 157 593 91 91 0
MAPK12 MAPK12 P53778 Mitogen-activated protein kinase 12 chr22 Not Cancer Driver No 1 biogrid 31 63 5 5 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie 45 11 0 0 0
MUC5B MUC5B Q9HC84 Mucin-5B chr11 Not Cancer Driver No 1 hippie 911 3134 586 586 0
MUC7 MUC7 Q8TAX7 Mucin-7 chr4 Not Cancer Driver No 1 intact, hippie 151 338 142 142 0
MYL2 MYL2 P10916 Myosin regulatory light chain 2, ventricular/cardiac muscle isoform chr12 Not Cancer Driver No 1 hippie 44 34 8 8 6
NPB NPB Q8NG41 Neuropeptide B chr17 Not Cancer Driver No 1 hippie 6 22 1 1 0
NTNG1_ENST00000370073 NTNG1 Q9Y2I2 Netrin-G1 chr1 Not Cancer Driver No 1 hippie 149 1 0 0 0
OMP OMP P47874 Olfactory marker protein chr11 Not Cancer Driver No 1 hippie 34 56 5 5 0
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 Not Cancer Driver No 1 biogrid 69 208 29 29 0
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 Not Cancer Driver No 1 hippie 62 104 13 13 2
PABPN1L PABPN1L A6NDY0 Embryonic polyadenylate-binding protein 2 chr16 Not Cancer Driver No 1 hippie 20 211 13 13 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PIM1 PIM1 P11309 Serine/threonine-protein kinase pim-1 chr6 Census, Compendium Yes 1 hippie 71 27 8 8 0
PLEKHG6_ENST00000011684 PLEKHG6 Q3KR16 Pleckstrin homology domain-containing family G member 6 chr12 Not Cancer Driver No 1 intact, hippie 103 471 65 65 0
PLEKHO1 PLEKHO1 Q53GL0 Pleckstrin homology domain-containing family O member 1 chr1 Not Cancer Driver No 1 hippie 55 341 46 46 0
PLK4 PLK4 O00444 Serine/threonine-protein kinase PLK4 chr4 Not Cancer Driver No 1 hippie, biogrid 102 451 45 45 0
PMPCB PMPCB O75439 Mitochondrial-processing peptidase subunit beta chr7 Not Cancer Driver No 1 hippie 55 22 3 3 5
PRKAB2 PRKAB2 O43741 5'-AMP-activated protein kinase subunit beta-2 chr1 Not Cancer Driver No 1 hippie 31 110 12 12 0
PRKAR2B PRKAR2B P31323 cAMP-dependent protein kinase type II-beta regulatory subunit chr7 Not Cancer Driver No 2 intact, hippie 60 125 4 4 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 Not Cancer Driver No 1 hippie 107 170 26 26 0
PRSS45_ENST00000620911 PRSS45P Q7RTY3 Putative serine protease 45 chr3 Not Cancer Driver No 1 hippie 35 0 0 0 0
RASSF6 RASSF6 Q6ZTQ3 Ras association domain-containing protein 6 chr4 Not Cancer Driver No 1 intact, hippie 53 74 10 10 0
RCAN1_ENST00000313806 RCAN1 P53805 Calcipressin-1 chr21 Not Cancer Driver No 1 intact, hippie 26 104 7 7 0
RCAN2_ENST00000330430 RCAN2 Q14206 Calcipressin-2 chr6 Not Cancer Driver No 2 intact, hippie 43 92 20 20 0
RHOBTB1 RHOBTB1 O94844 Rho-related BTB domain-containing protein 1 chr10 Not Cancer Driver No 1 intact, hippie 95 121 19 19 0
RING1 RING1 Q06587 E3 ubiquitin-protein ligase RING1 chr6 Not Cancer Driver No 1 hippie 60 302 44 44 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 Not Cancer Driver No 2 intact, hippie 66 295 39 39 0
RPS6KA4 RPS6KA4 O75676 Ribosomal protein S6 kinase alpha-4 chr11 Not Cancer Driver No 1 biogrid 72 220 11 11 0
SCAMP2 SCAMP2 O15127 Secretory carrier-associated membrane protein 2 chr15 Not Cancer Driver No 1 hippie 34 111 9 9 0
SLC39A3 SLC39A3 Q9BRY0 Zinc transporter ZIP3 chr19 Not Cancer Driver No 1 hippie 41 0 0 0 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 Census, Compendium Yes 1 intact, hippie, biogrid 64 141 35 35 3
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 59 2 0 0 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 62 488 56 56 0
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 Not Cancer Driver No 1 intact, hippie 32 25 5 5 0
SRRT SRRT Q9BXP5 Serrate RNA effector molecule homolog chr7 Not Cancer Driver No 1 hippie 146 595 108 108 0
ST3GAL5 ST3GAL5 Q9UNP4 Lactosylceramide alpha-2,3-sialyltransferase chr2 Not Cancer Driver No 1 hippie 43 27 0 0 0
STARD3NL STARD3NL O95772 STARD3 N-terminal-like protein chr7 Not Cancer Driver No 1 hippie 34 32 2 2 0
STBD1 STBD1 O95210 Starch-binding domain-containing protein 1 chr4 Not Cancer Driver No 2 intact, hippie 47 229 31 31 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 Census, Compendium Yes 1 hippie 75 135 14 14 9
STRADA STRADA Q7RTN6 STE20-related kinase adapter protein alpha chr17 Not Cancer Driver No 1 biogrid 49 118 14 14 0
TIMM10_ENST00000525587 TIMM10 P62072 Mitochondrial import inner membrane translocase subunit Tim10 chr11 Not Cancer Driver No 1 hippie 6 43 6 6 0
TNFRSF19 TNFRSF19 Q9NS68 Tumor necrosis factor receptor superfamily member 19 chr13 Not Cancer Driver No 1 intact, hippie 72 103 19 19 0
TRAPPC12 TRAPPC12 Q8WVT3 Trafficking protein particle complex subunit 12 chr2 Not Cancer Driver No 2 intact, hippie 88 318 31 31 0
TSFM_ENST00000454289 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie 37 74 7 7 2
TTL TTL Q8NG68 Tubulin--tyrosine ligase chr2 Not Cancer Driver No 1 hippie 37 24 0 0 0
UBL7_ENST00000565335 UBL7 Q96S82 Ubiquitin-like protein 7 chr15 Not Cancer Driver No 1 hippie 31 192 22 22 0
UBXN4 UBXN4 Q92575 UBX domain-containing protein 4 chr2 Not Cancer Driver No 1 hippie 69 302 41 41 0
UCP2 UCP2 P55851 Mitochondrial uncoupling protein 2 chr11 Not Cancer Driver No 2 intact, hippie 31 11 3 3 0
VAPA_ENST00000400000 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 1 hippie 24 184 14 14 0
VASH1 VASH1 Q7L8A9 Tubulinyl-Tyr carboxypeptidase 1 chr14 Not Cancer Driver No 1 hippie 39 215 18 18 0
WDR6_ENST00000608424 WDR6 Q9NNW5 WD repeat-containing protein 6 chr3 Not Cancer Driver No 1 intact, hippie 166 105 13 13 0
ZBBX_ENST00000392766 ZBBX A8MT70 Zinc finger B-box domain-containing protein 1 chr3 Not Cancer Driver No 1 intact, hippie 259 462 155 155 0
ZNF154 ZNF154 Q13106 Zinc finger protein 154 chr19 Not Cancer Driver No 1 hippie 65 104 22 22 0
ZWINT ZWINT O95229 ZW10 interactor chr10 Not Cancer Driver No 1 hippie 65 168 44 44 0