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AKAP2_ENST00000259318 ,AKAP2 ,Q9Y2D5
  • Uniprot Accession= Q9Y2D5
  • Ensembl Transcript= ENST00000259318.7
  • Uniprot Name= AKAP2
  • Name= A-kinase anchor protein 2
  • Chromosome= chr9
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 21
  • Number of Interaction partner in biogrid: 4
  • Number of Interaction partner in hippie: 79
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 112 43 5 5 5
ANK3 ANK3 Q12955 Ankyrin-3 chr10 Not Cancer Driver No 1 hippie 860 3054 579 579 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 intact, hippie 144 767 104 104 2
ARHGAP11A ARHGAP11A Q6P4F7 Rho GTPase-activating protein 11A chr15 Not Cancer Driver No 1 intact, hippie 127 696 93 93 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 40 25 6 6 1
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 Not Cancer Driver No 1 intact, hippie 66 23 5 5 2
BABAM1_ENST00000601043 BABAM1 Q9NWV8 BRISC and BRCA1-A complex member 1 chr19 Not Cancer Driver No 1 hippie 35 113 14 14 0
BABAM2_ENST00000342045 BABAM2 Q9NXR7 BRISC and BRCA1-A complex member 2 chr2 Not Cancer Driver No 1 hippie 52 0 0 0 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 80 45 4 4 0
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 1 hippie 37 19 0 0 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CERS2_ENST00000368954 CERS2 Q96G23 Ceramide synthase 2 chr1 Not Cancer Driver No 1 hippie 38 36 4 4 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CLTA CLTA P09496 Clathrin light chain A chr9 Not Cancer Driver No 1 hippie 20 192 12 12 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CSTF2_ENST00000372972 CSTF2 P33240 Cleavage stimulation factor subunit 2 chrX Not Cancer Driver No 1 hippie 85 484 72 72 0
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 42 123 9 9 1
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 Not Cancer Driver No 1 intact, hippie 84 510 73 73 0
DYNC1LI2 DYNC1LI2 O43237 Cytoplasmic dynein 1 light intermediate chain 2 chr16 Not Cancer Driver No 1 hippie 43 211 14 14 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EZR EZR P15311 Ezrin chr6 Census Yes 1 intact, hippie 66 295 35 35 0
FGD5 FGD5 Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 chr3 Compendium Yes 1 hippie, biogrid 275 915 180 180 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 intact, hippie 416 1456 214 214 28
FMNL3_ENST00000550488 FMNL3 Q8IVF7 Formin-like protein 3 chr12 Not Cancer Driver No 1 hippie 140 284 37 37 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
INS INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 15 5 1 1 22
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 intact, hippie 183 351 35 35 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 Census, Compendium Yes 1 hippie 122 586 67 67 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 86 94 13 13 1
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie 88 687 81 81 0
LUZP4 LUZP4 Q9P127 Leucine zipper protein 4 chrX Not Cancer Driver No 1 hippie 74 313 74 74 0
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie 14 328 14 14 0
MAU2 MAU2 Q9Y6X3 MAU2 chromatid cohesion factor homolog chr19 Not Cancer Driver No 1 hippie 68 36 1 1 0
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 310 1120 160 160 17
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie 268 1237 176 176 0
MYO5C MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 intact, hippie 204 394 43 43 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 1 intact, hippie 48 111 17 17 0
NUDCD2 NUDCD2 Q8WVJ2 NudC domain-containing protein 2 chr5 Not Cancer Driver No 1 hippie 12 39 6 6 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PDLIM7 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 Not Cancer Driver No 1 hippie 48 244 20 20 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 intact, hippie 154 268 61 61 2
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie 158 186 21 21 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 hippie 152 919 121 121 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 1 intact, hippie 47 25 5 5 5
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 2 intact, hippie 53 24 0 0 2
PRKACB_ENST00000370689 PRKACB P22694 cAMP-dependent protein kinase catalytic subunit beta chr1 Not Cancer Driver No 1 intact, hippie 50 26 6 6 4
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 Census, Compendium Yes 1 hippie 39 66 11 11 17
PRKAR2A PRKAR2A P13861 cAMP-dependent protein kinase type II-alpha regulatory subunit chr3 Not Cancer Driver No 1 hippie 37 149 13 13 0
PRKAR2B PRKAR2B P31323 cAMP-dependent protein kinase type II-beta regulatory subunit chr7 Not Cancer Driver No 3 intact, hippie, biogrid 60 125 4 4 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 Compendium Yes 1 hippie 118 246 34 34 0
RBPMS_ENST00000320203 RBPMS Q93062 RNA-binding protein with multiple splicing chr8 Not Cancer Driver No 1 hippie 23 87 11 11 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 Not Cancer Driver No 1 hippie 71 297 37 37 1
RPP38_ENST00000378202 RPP38 P78345 Ribonuclease P protein subunit p38 chr10 Not Cancer Driver No 1 hippie 36 118 19 19 0
SART3 SART3 Q15020 Squamous cell carcinoma antigen recognized by T-cells 3 chr12 Not Cancer Driver No 1 hippie 101 404 45 45 0
SCARB2 SCARB2 Q14108 Lysosome membrane protein 2 chr4 Not Cancer Driver No 1 hippie 61 13 3 3 1
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
SYDE2 SYDE2 Q5VT97 Rho GTPase-activating protein SYDE2 chr1 Not Cancer Driver No 1 intact, hippie 136 693 69 69 0
SYNPO SYNPO Q8N3V7 Synaptopodin chr5 Not Cancer Driver No 1 intact, hippie 103 918 102 102 0
TES TES Q9UGI8 Testin chr7 Not Cancer Driver No 1 hippie 56 100 7 7 0
TFG TFG Q92734 Protein TFG chr3 Census, Compendium Yes 1 hippie 45 290 34 34 3
TIAF1 MYO18A O95411 Putative TGFB1-induced anti-apoptotic factor 1 chr17 Not Cancer Driver No 1 hippie 16 30 5 5 0
TJP2_ENST00000377245 TJP2 Q9UDY2 Tight junction protein ZO-2 chr9 Not Cancer Driver No 1 hippie, biogrid 149 919 113 113 1
VASP VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 1 hippie 39 335 34 34 0
VAV1 VAV1 P15498 Proto-oncogene vav chr19 Census, Compendium Yes 1 intact, hippie 165 113 19 19 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VMP1 VMP1 Q96GC9 Vacuole membrane protein 1 chr17 Not Cancer Driver No 1 hippie 57 68 11 11 0
WASHC5 WASHC5 Q12768 WASH complex subunit 5 chr8 Not Cancer Driver No 1 hippie 152 23 6 6 6
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 Not Cancer Driver No 1 hippie 30 41 2 2 0
ZYX ZYX Q15942 Zyxin chr7 Not Cancer Driver No 1 hippie 83 385 52 52 0