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AGT ,AGT ,P01019
  • Number of Interaction partner in intact: 4
  • Number of Interaction partner in biogrid: 8
  • Number of Interaction partner in hippie: 42
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACE ACE P12821 Angiotensin-converting enzyme chr17 Not Cancer Driver No 1 hippie 201 86 8 8 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX Not Cancer Driver No 3 intact, hippie 104 68 5 5 0
AGT AGT P01019 Angiotensinogen chr1 Not Cancer Driver No 1 hippie 85 33 10 10 1
AGTR1_ENST00000349243 AGTR1 P30556 Type-1 angiotensin II receptor chr3 Not Cancer Driver No 2 intact, hippie 95 0 0 0 1
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX Not Cancer Driver No 2 intact, hippie 98 0 0 0 0
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX Not Cancer Driver No 1 hippie 56 0 0 0 2
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 2 hippie, biogrid 65 334 38 38 0
CIR1 CIR1 Q86X95 Corepressor interacting with RBPJ 1 chr2 Not Cancer Driver No 1 hippie, biogrid 46 385 42 42 0
CMA1 CMA1 P23946 Chymase chr14 Not Cancer Driver No 1 hippie 47 9 1 1 0
CTSG CTSG P08311 Cathepsin G chr14 Not Cancer Driver No 1 hippie 65 80 29 29 0
DNPEP_ENST00000273075 DNPEP Q9ULA0 Aspartyl aminopeptidase chr2 Not Cancer Driver No 1 hippie 55 90 8 8 0
ECE1 ECE1 P42892 Endothelin-converting enzyme 1 chr1 Not Cancer Driver No 1 hippie 118 99 26 26 1
EIF2B4_ENST00000347454 EIF2B4 Q9UI10 Translation initiation factor eIF-2B subunit delta chr2 Not Cancer Driver No 1 hippie 57 212 29 29 7
ENPEP ENPEP Q07075 Glutamyl aminopeptidase chr4 Compendium Yes 1 hippie 235 130 44 44 0
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 1 hippie 94 646 93 93 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
GSDMB GSDMB Q8TAX9 Gasdermin-B chr17 Not Cancer Driver No 1 hippie 50 84 11 11 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie, biogrid 73 282 35 35 0
ITSN2 ITSN2 Q9NZM3 Intersectin-2 chr2 Not Cancer Driver No 1 hippie 207 680 92 92 0
KLK10_ENST00000358789 KLK10 O43240 Kallikrein-10 chr19 Not Cancer Driver No 1 hippie, biogrid 35 30 8 8 0
KNG1 KNG1 P01042 Kininogen-1 chr3 Not Cancer Driver No 1 hippie 130 294 66 66 1
LNPEP LNPEP Q9UIQ6 Leucyl-cystinyl aminopeptidase chr5 Not Cancer Driver No 1 hippie 115 103 8 8 0
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 Not Cancer Driver No 1 hippie 47 5 2 2 0
MEP1A MEP1A Q16819 Meprin A subunit alpha chr6 Not Cancer Driver No 1 hippie 163 140 20 20 0
MME_ENST00000492661 MME P08473 Neprilysin chr3 Not Cancer Driver No 1 hippie 189 40 17 17 4
NDUFA3 NDUFA3 O95167 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 chr19 Not Cancer Driver No 2 hippie, biogrid 7 27 4 4 0
NME4 NME4 O00746 Nucleoside diphosphate kinase, mitochondrial chr16 Not Cancer Driver No 1 hippie 13 41 4 4 0
PHF11 PHF11 Q9UIL8 PHD finger protein 11 chr13 Not Cancer Driver No 1 hippie, biogrid 34 82 10 10 0
PRCP_ENST00000313010 PRCP P42785 Lysosomal Pro-X carboxypeptidase chr11 Not Cancer Driver No 2 intact, hippie 58 0 0 0 0
PREP PREP P48147 Prolyl endopeptidase chr6 Not Cancer Driver No 1 hippie 87 23 1 1 0
PRG2 PRG2 P13727 Bone marrow proteoglycan chr11 Not Cancer Driver No 1 hippie 45 65 15 15 0
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 hippie 83 72 6 6 0
REN REN P00797 Renin chr1 Not Cancer Driver No 1 hippie 60 10 0 0 3
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 2 hippie, biogrid 119 232 34 34 3
SLFN12_ENST00000452764 SLFN12 Q8IYM2 Ribonuclease SLFN12 chr17 Not Cancer Driver No 1 hippie 78 7 1 1 0
SNX12 SNX12 Q9UMY4 Sorting nexin-12 chrX Not Cancer Driver No 1 hippie 22 28 4 4 0
TGOLN2_ENST00000377386 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 hippie 51 399 46 46 0
TMEM185A TMEM185A Q8NFB2 Transmembrane protein 185A chrX Not Cancer Driver No 1 hippie 29 19 0 0 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
UBE2U_ENST00000611228 UBE2U Q5VVX9 Ubiquitin-conjugating enzyme E2 U chr1 Not Cancer Driver No 1 hippie, biogrid 38 66 1 1 0
VKORC1L1_ENST00000360768 VKORC1L1 Q8N0U8 Vitamin K epoxide reductase complex subunit 1-like protein 1 chr7 Not Cancer Driver No 1 hippie 20 0 0 0 0