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AGRN ,AGRN ,O00468
  • Number of Interaction partner in intact: 21
  • Number of Interaction partner in biogrid: 27
  • Number of Interaction partner in hippie: 249
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAP2 ACAP2 Q15057 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 chr3 Not Cancer Driver No 1 hippie 97 287 40 40 0
ACLY_ENST00000590151 ACLY P53396 ATP-citrate synthase chr17 Not Cancer Driver No 1 hippie 120 114 12 12 0
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 hippie 70 48 14 14 84
ACTN1_ENST00000193403 ACTN1 P12814 Alpha-actinin-1 chr14 Not Cancer Driver No 1 hippie 108 195 30 30 6
ACTN2_ENST00000366578 ACTN2 P35609 Alpha-actinin-2 chr1 Not Cancer Driver No 1 hippie 227 131 29 29 9
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 Not Cancer Driver No 1 hippie 131 244 42 42 8
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 Not Cancer Driver No 1 hippie 80 182 17 17 0
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
AGRN AGRN O00468 Agrin chr1 Not Cancer Driver No 1 hippie 188 490 40 40 5
AIF1L_ENST00000247291 AIF1L Q9BQI0 Allograft inflammatory factor 1-like chr9 Not Cancer Driver No 1 hippie 9 44 1 1 0
AKAP11 AKAP11 Q9UKA4 A-kinase anchor protein 11 chr13 Not Cancer Driver No 1 hippie 196 922 91 91 0
ALDOC_ENST00000395321 ALDOC P09972 Fructose-bisphosphate aldolase C chr17 Not Cancer Driver No 1 hippie 41 79 4 4 0
AMFR AMFR Q9UKV5 E3 ubiquitin-protein ligase AMFR chr16 Not Cancer Driver No 1 hippie 73 229 30 30 0
ANK3 ANK3 Q12955 Ankyrin-3 chr10 Not Cancer Driver No 1 hippie 860 3054 579 579 0
AP2A2_ENST00000448903 AP2A2 O94973 AP-2 complex subunit alpha-2 chr11 Not Cancer Driver No 1 hippie 100 145 12 12 0
APOE APOE P02649 Apolipoprotein E chr19 Not Cancer Driver No 1 hippie 25 124 6 6 12
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 intact, hippie 128 418 71 71 17
ARHGDIA_ENST00000580685 ARHGDIA P52565 Rho GDP-dissociation inhibitor 1 chr17 Not Cancer Driver No 1 hippie 25 50 6 6 0
ARL6IP4_ENST00000543566 ARL6IP4 Q66PJ3-3 Isoform 3 of ADP-ribosylation factor-like protein 6-interacting protein 4 chr12 Not Cancer Driver No 1 hippie 16 386 15 15 0
ARMCX5_ENST00000372742 ARMCX5 Q6P1M9 Armadillo repeat-containing X-linked protein 5 chrX Not Cancer Driver No 1 hippie 67 239 31 31 0
ASAP2 ASAP2 O43150 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 chr2 Not Cancer Driver No 1 hippie 141 453 63 63 0
ASPH ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 Not Cancer Driver No 1 hippie 109 373 53 53 1
ATN1_ENST00000396684 ATN1 P54259 Atrophin-1 chr12 Not Cancer Driver No 1 intact, hippie 141 1176 139 139 6
ATXN7_ENST00000487717 ATXN7 O15265 Ataxin-7 chr3 Not Cancer Driver No 1 hippie 95 797 82 82 0
B4GAT1 B4GAT1 O43505 Beta-1,4-glucuronyltransferase 1 chr11 Not Cancer Driver No 1 hippie 52 4 0 0 2
BGN BGN P21810 Biglycan chrX Not Cancer Driver No 1 hippie 63 26 3 3 2
BOLL_ENST00000392296 BOLL Q8N9W6 Protein boule-like chr2 Not Cancer Driver No 1 intact, hippie 59 78 22 22 0
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 Not Cancer Driver No 1 hippie 90 399 45 45 4
C1QTNF7_ENST00000429690 C1QTNF7 Q9BXJ2 Complement C1q tumor necrosis factor-related protein 7 chr4 Not Cancer Driver No 1 hippie, biogrid 45 124 18 18 0
C1orf54 C1orf54 Q8WWF1 Uncharacterized protein C1orf54 chr1 Not Cancer Driver No 1 hippie, biogrid 17 28 3 3 0
C3 C3 P01024 Complement C3 chr19 Not Cancer Driver No 1 hippie 337 287 50 50 12
CACNA1A_ENST00000360228 CACNA1A O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A chr19 Not Cancer Driver No 1 hippie 436 1144 132 132 46
CAMKV CAMKV Q8NCB2 CaM kinase-like vesicle-associated protein chr3 Not Cancer Driver No 2 intact, hippie, biogrid 87 226 30 30 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 hippie 65 334 38 38 0
CBLN4 CBLN4 Q9NTU7 Cerebellin-4 chr20 Not Cancer Driver No 1 hippie, biogrid 62 20 10 10 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 hippie 52 214 31 31 0
CFC1 CFC1 P0CG37 Cryptic protein chr2 Not Cancer Driver No 1 hippie, biogrid 25 68 23 23 1
CHCHD4_ENST00000396914 CHCHD4 Q8N4Q1 Mitochondrial intermembrane space import and assembly protein 40 chr3 Not Cancer Driver No 1 hippie 18 82 8 8 0
CKB CKB P12277 Creatine kinase B-type chr14 Not Cancer Driver No 1 hippie 31 102 4 4 0
CKMT2_ENST00000437669 CKMT2 P17540 Creatine kinase S-type, mitochondrial chr5 Not Cancer Driver No 1 hippie 70 68 12 12 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 Not Cancer Driver No 1 hippie 22 42 4 4 1
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie 190 71 6 6 1
COL4A2 COL4A2 P08572 Collagen alpha-2(IV) chain chr13 Not Cancer Driver No 1 hippie 264 1462 234 234 2
COL6A1 COL6A1 P12109 Collagen alpha-1(VI) chain chr21 Not Cancer Driver No 1 hippie 145 434 61 61 12
COL6A2 COL6A2 P12110 Collagen alpha-2(VI) chain chr21 Not Cancer Driver No 1 hippie 220 460 97 97 10
COPS2_ENST00000388901 COPS2 P61201 COP9 signalosome complex subunit 2 chr15 Not Cancer Driver No 1 hippie 59 59 9 9 0
CREB5 CREB5 Q02930 Cyclic AMP-responsive element-binding protein 5 chr7 Not Cancer Driver No 1 hippie 92 494 89 89 0
CRP CRP P02741 C-reactive protein chr1 Not Cancer Driver No 2 intact, hippie, biogrid 59 0 0 0 0
CSNK2A2 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 Not Cancer Driver No 1 hippie 43 13 1 1 0
CTNNBL1 CTNNBL1 Q8WYA6 Beta-catenin-like protein 1 chr20 Not Cancer Driver No 1 hippie 72 158 24 24 0
CZIB CZIB Q9NWV4 CXXC motif containing zinc binding protein chr1 Not Cancer Driver No 1 hippie 19 2 1 1 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 Not Cancer Driver No 4 intact, hippie 102 485 61 61 4
DBI_ENST00000355857 DBI P07108 Acyl-CoA-binding protein chr2 Not Cancer Driver No 1 hippie 13 27 6 6 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 Census Yes 1 hippie 74 225 23 23 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 Not Cancer Driver No 1 hippie 230 1119 135 135 0
DMD DMD P11532 Dystrophin chrX Not Cancer Driver No 1 hippie 895 1399 329 329 14
DNAJB9 DNAJB9 Q9UBS3 DnaJ homolog subfamily B member 9 chr7 Not Cancer Driver No 1 hippie, biogrid 30 107 15 15 0
DNAJC21_ENST00000342382 DNAJC21 Q5F1R6 DnaJ homolog subfamily C member 21 chr5 Not Cancer Driver No 1 hippie 82 342 51 51 1
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 Not Cancer Driver No 1 hippie 96 514 64 64 0
EDN3_ENST00000371028 EDN3 P14138 Endothelin-3 chr20 Not Cancer Driver No 1 hippie, biogrid 69 140 44 44 3
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 Not Cancer Driver No 1 hippie 74 121 17 17 3
EEF2 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 hippie 111 78 14 14 1
EIF4A2 EIF4A2 Q14240 Eukaryotic initiation factor 4A-II chr3 Census Yes 1 hippie 77 27 14 14 0
EIF5_ENST00000392715 EIF5 P55010 Eukaryotic translation initiation factor 5 chr14 Not Cancer Driver No 1 hippie 64 185 23 23 0
ELSPBP1 ELSPBP1 Q96BH3 Epididymal sperm-binding protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 54 0 0 0 0
EMD EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie 42 160 28 28 4
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie 51 21 2 2 0
ENO3 ENO3 P13929 Beta-enolase chr17 Not Cancer Driver No 1 hippie 46 26 1 1 2
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 1 hippie 94 646 93 93 0
FAM160A2_ENST00000449352 FHIP1B Q8N612 FHF complex subunit HOOK interacting protein 1B chr11 Not Cancer Driver No 1 intact 129 415 54 54 0
FAM160B1 FHIP2A Q5W0V3 FHF complex subunit HOOK interacting protein 2A chr10 Not Cancer Driver No 1 intact 92 130 13 13 0
FAM206A ABITRAM Q9NX38 Protein Abitram chr9 Not Cancer Driver No 1 hippie 10 12 1 1 0
FBLN1 FBLN1 P23142 Fibulin-1 chr22 Compendium Yes 1 hippie 122 22 3 3 0
FBLN5 FBLN5 Q9UBX5 Fibulin-5 chr14 Not Cancer Driver No 1 hippie, biogrid 77 11 2 2 16
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 21 75 1 1 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FGF4 FGF4 P08620 Fibroblast growth factor 4 chr11 Not Cancer Driver No 1 hippie, biogrid 16 21 3 3 0
FHL1_ENST00000345434 FHL1 Q13642 Four and a half LIM domains protein 1 chrX Not Cancer Driver No 1 hippie 56 51 7 7 13
FLNB_ENST00000295956 FLNB O75369 Filamin-B chr3 Not Cancer Driver No 1 hippie 362 1183 170 170 19
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
FSTL1 FSTL1 Q12841 Follistatin-related protein 1 chr3 Not Cancer Driver No 1 hippie 41 51 7 7 0
GFI1B GFI1B Q5VTD9 Zinc finger protein Gfi-1b chr9 Not Cancer Driver No 1 intact, hippie 50 142 23 23 0
GLS GLS O94925 Glutaminase kidney isoform, mitochondrial chr2 Not Cancer Driver No 1 hippie 71 187 9 9 3
GNAO1_ENST00000638705 GNAO1 P09471 Guanine nucleotide-binding protein G(o) subunit alpha chr16 Not Cancer Driver No 1 hippie 54 10 0 0 15
GNS GNS P15586 N-acetylglucosamine-6-sulfatase chr12 Not Cancer Driver No 1 hippie 48 22 0 0 3
GRN GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie 76 29 6 6 1
GTF2A1 GTF2A1 P52655 Transcription initiation factor IIA subunit 1 chr14 Not Cancer Driver No 1 hippie 49 260 38 38 0
HADHA HADHA P40939 Trifunctional enzyme subunit alpha, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 72 19 2 2 5
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 1 hippie 35 203 29 29 0
HDLBP_ENST00000391976 HDLBP Q00341 Vigilin chr2 Not Cancer Driver No 1 hippie 195 555 87 87 0
HMGA1 HMGA1 P17096 High mobility group protein HMG-I/HMG-Y chr6 Census Yes 1 hippie 6 107 6 6 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 hippie 70 290 58 58 4
HNRNPAB HNRNPAB Q99729 Heterogeneous nuclear ribonucleoprotein A/B chr5 Not Cancer Driver No 1 hippie 31 202 11 11 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 Not Cancer Driver No 1 hippie 75 302 59 59 0
HNRNPUL2 HNRNPUL2 Q1KMD3 Heterogeneous nuclear ribonucleoprotein U-like protein 2 chr11 Not Cancer Driver No 1 hippie 71 418 35 35 0
HOXA1_ENST00000643460 HOXA1 P49639 Homeobox protein Hox-A1 chr7 Not Cancer Driver No 1 hippie 90 262 68 68 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie 100 254 43 43 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie 94 268 35 35 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 20
IGFL3 IGFL3 Q6UXB1 Insulin growth factor-like family member 3 chr19 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 0
INSR INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 hippie 190 280 57 57 64
IPO4 IPO4 Q8TEX9 Importin-4 chr14 Not Cancer Driver No 1 hippie 106 87 5 5 0
IPO9 IPO9 Q96P70 Importin-9 chr1 Not Cancer Driver No 1 hippie 145 102 22 22 0
IQGAP2 IQGAP2 Q13576 Ras GTPase-activating-like protein IQGAP2 chr5 Not Cancer Driver No 1 hippie 237 255 50 50 0
IRS4 IRS4 O14654 Insulin receptor substrate 4 chrX Census, Compendium Yes 1 hippie 297 798 203 203 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KRT19 KRT19 P08727 Keratin, type I cytoskeletal 19 chr17 Not Cancer Driver No 1 hippie 57 165 19 19 0
KRT78 KRT78 Q8N1N4 Keratin, type II cytoskeletal 78 chr12 Not Cancer Driver No 1 hippie 96 122 27 27 0
LAIR2 LAIR2 Q6ISS4 Leukocyte-associated immunoglobulin-like receptor 2 chr19 Not Cancer Driver No 1 hippie, biogrid 46 77 26 26 0
LAMB4 LAMB4 A4D0S4 Laminin subunit beta-4 chr7 Not Cancer Driver No 1 intact 344 247 53 53 0
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie 40 9 0 0 0
LLCFC1 LLCFC1 Q96L11-3 Isoform 3 of Sperm-egg fusion protein LLCFC1 chr7 Not Cancer Driver No 1 hippie 42 62 17 17 0
LPIN1_ENST00000256720 LPIN1 Q14693 Phosphatidate phosphatase LPIN1 chr2 Not Cancer Driver No 1 hippie 120 447 70 70 0
M6PR M6PR P20645 Cation-dependent mannose-6-phosphate receptor chr12 Not Cancer Driver No 1 hippie 16 35 4 4 0
MAGED1_ENST00000326587 MAGED1 Q9Y5V3 Melanoma-associated antigen D1 chrX Not Cancer Driver No 1 hippie 131 457 71 71 0
MANEA MANEA Q5SRI9 Glycoprotein endo-alpha-1,2-mannosidase chr6 Not Cancer Driver No 1 hippie, biogrid 91 80 14 14 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 Not Cancer Driver No 1 hippie 332 1947 278 278 0
MAP1S MAP1S Q66K74 Microtubule-associated protein 1S chr19 Not Cancer Driver No 1 hippie 118 527 48 48 0
MAX MAX P61244 Protein max chr14 Census, Compendium Yes 1 hippie, biogrid 45 160 45 45 9
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MT1G MT1G P13640 Metallothionein-1G chr16 Not Cancer Driver No 1 hippie 9 0 0 0 0
MTHFD1 MTHFD1 P11586 C-1-tetrahydrofolate synthase, cytoplasmic chr14 Not Cancer Driver No 1 hippie 103 129 11 11 6
MYBPC1_ENST00000550270 MYBPC1 Q00872 Myosin-binding protein C, slow-type chr12 Not Cancer Driver No 1 hippie 227 220 38 38 7
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYH11_ENST00000300036 MYH11 P35749 Myosin-11 chr16 Census, Compendium Yes 1 hippie 353 1180 201 201 2
MYH14_ENST00000596571 MYH14 Q7Z406 Myosin-14 chr19 Not Cancer Driver No 1 hippie 275 1215 169 169 5
MYH3 MYH3 P11055 Myosin-3 chr17 Not Cancer Driver No 1 hippie 312 967 179 179 14
MYH7 MYH7 P12883 Myosin-7 chr14 Not Cancer Driver No 1 hippie 464 1107 276 276 200
MYH8 MYH8 P13535 Myosin-8 chr17 Not Cancer Driver No 1 hippie 498 1086 315 315 2
MYL12B_ENST00000237500 MYL12B O14950 Myosin regulatory light chain 12B chr18 Not Cancer Driver No 1 hippie 23 61 13 13 0
MYL3 MYL3 P08590 Myosin light chain 3 chr3 Not Cancer Driver No 1 hippie 21 99 9 9 5
MYOT MYOT Q9UBF9 Myotilin chr5 Not Cancer Driver No 1 hippie 78 280 39 39 6
NAA15 NAA15 Q9BXJ9 N-alpha-acetyltransferase 15, NatA auxiliary subunit chr4 Not Cancer Driver No 1 hippie 95 115 17 17 0
NCOR2 NCOR2 Q9Y618 Nuclear receptor corepressor 2 chr12 Census, Compendium Yes 1 hippie 373 2355 356 356 0
NEIL2 NEIL2 Q969S2 Endonuclease 8-like 2 chr8 Not Cancer Driver No 1 hippie 31 145 14 14 0
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 intact, hippie 69 252 26 26 16
NID2 NID2 Q14112 Nidogen-2 chr14 Not Cancer Driver No 2 hippie, biogrid 270 415 96 96 0
NIN NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 239 1392 164 164 2
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 29 249 22 22 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NSFL1C_ENST00000216879 NSFL1C Q9UNZ2 NSFL1 cofactor p47 chr20 Not Cancer Driver No 1 hippie 56 266 39 39 0
NT5C1B NT5C1B Q96P26 Cytosolic 5'-nucleotidase 1B chr2 Not Cancer Driver No 1 hippie 136 253 58 58 0
NUDCD1 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 75 38 4 4 0
NUFIP2 NUFIP2 Q7Z417 Nuclear fragile X mental retardation-interacting protein 2 chr17 Not Cancer Driver No 1 intact, hippie 67 623 62 62 0
NUP98_ENST00000359171 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 Census Yes 1 hippie 227 1008 107 107 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OLFM3 OLFM3 Q96PB7 Noelin-3 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 148 44 17 17 0
OLFML3 OLFML3 Q9NRN5 Olfactomedin-like protein 3 chr1 Not Cancer Driver No 1 hippie 55 105 14 14 0
OS9 OS9 Q13438 Protein OS-9 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 72 451 49 49 0
OSER1 OSER1 Q9NX31 Oxidative stress-responsive serine-rich protein 1 chr20 Not Cancer Driver No 1 hippie 32 221 28 28 0
PA2G4 PA2G4 Q9UQ80 Proliferation-associated protein 2G4 chr12 Not Cancer Driver No 1 hippie 45 128 18 18 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 1 hippie 100 317 55 55 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 hippie 119 320 34 34 0
PAXX PAXX Q9BUH6 Protein PAXX chr9 Not Cancer Driver No 1 hippie 22 121 17 17 0
PC PC P11498 Pyruvate carboxylase, mitochondrial chr11 Not Cancer Driver No 1 hippie 185 172 27 27 9
PCNX3 PCNX3 Q9H6A9 Pecanex-like protein 3 chr11 Not Cancer Driver No 1 hippie 185 839 71 71 0
PCOLCE PCOLCE Q15113 Procollagen C-endopeptidase enhancer 1 chr7 Not Cancer Driver No 1 hippie 46 187 18 18 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 Census, Compendium Yes 1 hippie, biogrid 290 173 45 45 2
PDIA3 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 Not Cancer Driver No 1 hippie 57 98 11 11 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 33 121 12 12 0
PGAM1 PGAM1 P18669 Phosphoglycerate mutase 1 chr10 Not Cancer Driver No 1 hippie 20 70 5 5 0
PGD PGD P52209 6-phosphogluconate dehydrogenase, decarboxylating chr1 Not Cancer Driver No 1 hippie 73 19 3 3 0
PGM1_ENST00000371084 PGM1 P36871 Phosphoglucomutase-1 chr1 Not Cancer Driver No 1 hippie 62 31 3 3 13
PGRMC1 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX Not Cancer Driver No 1 hippie 30 74 16 16 0
PHC2 PHC2 Q8IXK0 Polyhomeotic-like protein 2 chr1 Not Cancer Driver No 1 hippie 101 674 67 67 0
PI15 PI15 O43692 Peptidase inhibitor 15 chr8 Not Cancer Driver No 1 hippie, biogrid 87 4 1 1 0
PIP5K1A PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 Not Cancer Driver No 1 hippie 74 216 29 29 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PLTP PLTP P55058 Phospholipid transfer protein chr20 Not Cancer Driver No 1 hippie 78 27 6 6 0
PNPLA6 PNPLA6 Q8IY17 Patatin-like phospholipase domain-containing protein 6 chr19 Not Cancer Driver No 1 hippie 171 367 49 49 18
PPA2 PPA2 Q9H2U2 Inorganic pyrophosphatase 2, mitochondrial chr4 Not Cancer Driver No 1 hippie 49 71 9 9 9
PPP3R1 PPP3R1 P63098 Calcineurin subunit B type 1 chr2 Not Cancer Driver No 1 hippie 19 1 0 0 0
PRKAR2A PRKAR2A P13861 cAMP-dependent protein kinase type II-alpha regulatory subunit chr3 Not Cancer Driver No 1 hippie 37 149 13 13 0
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PRSS1 PRSS1 P07477 Serine protease 1 chr7 Not Cancer Driver No 1 hippie 121 0 0 0 12
PSMD4_ENST00000368884 PSMD4 P55036 26S proteasome non-ATPase regulatory subunit 4 chr1 Not Cancer Driver No 1 hippie 43 243 25 25 0
PTMA PTMA P06454 Prothymosin alpha chr2 Compendium Yes 1 hippie 10 111 10 10 0
PTMS_ENST00000309083 PTMS P20962 Parathymosin chr12 Not Cancer Driver No 1 hippie 10 102 10 10 0
PYGM PYGM P11217 Glycogen phosphorylase, muscle form chr11 Not Cancer Driver No 1 hippie 153 39 4 4 17
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 174 291 99 99 0
QPCT QPCT Q16769 Glutaminyl-peptide cyclotransferase chr2 Not Cancer Driver No 1 hippie 44 41 3 3 0
RABGAP1 RABGAP1 Q9Y3P9 Rab GTPase-activating protein 1 chr9 Not Cancer Driver No 1 hippie 114 407 40 40 0
RANBP1_ENST00000331821 RANBP1 P43487 Ran-specific GTPase-activating protein chr22 Not Cancer Driver No 1 hippie 19 137 16 16 0
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 Not Cancer Driver No 1 hippie 132 495 71 71 0
REST REST Q13127 RE1-silencing transcription factor chr4 Not Cancer Driver No 1 hippie 142 868 113 113 4
RFC3 RFC3 P40938 Replication factor C subunit 3 chr13 Not Cancer Driver No 1 hippie 31 13 1 1 0
RNF180 RNF180 Q86T96 E3 ubiquitin-protein ligase RNF180 chr5 Not Cancer Driver No 1 hippie 80 190 26 26 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 Not Cancer Driver No 1 hippie 142 319 45 45 0
RPL22 RPL22 P35268 60S ribosomal protein L22 chr1 Census, Compendium Yes 1 hippie 26 15 1 1 0
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie 50 69 3 3 0
RPS27L RPS27L Q71UM5 40S ribosomal protein S27-like chr15 Not Cancer Driver No 1 hippie 4 22 2 2 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 Not Cancer Driver No 1 hippie 22 48 4 4 0
RRAGA RRAGA Q7L523 Ras-related GTP-binding protein A chr9 Not Cancer Driver No 1 hippie 30 0 0 0 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 Not Cancer Driver No 1 hippie 18 76 7 7 0
SACM1L SACM1L Q9NTJ5 Phosphatidylinositol-3-phosphatase SAC1 chr3 Not Cancer Driver No 1 hippie 41 0 0 0 0
SCGB1A1 SCGB1A1 P11684 Uteroglobin chr11 Not Cancer Driver No 1 hippie 12 14 2 2 0
SCGB2A2 SCGB2A2 Q13296 Mammaglobin-A chr11 Not Cancer Driver No 1 hippie, biogrid 11 0 0 0 0
SDF2L1 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 16 130 9 9 0
SEC23A SEC23A Q15436 Protein transport protein Sec23A chr14 Not Cancer Driver No 1 hippie 100 73 8 8 1
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 Not Cancer Driver No 1 hippie 142 47 28 28 0
SKI SKI P12755 Ski oncogene chr1 Census Yes 1 hippie 44 432 26 26 14
SLC12A4_ENST00000316341 SLC12A4 Q9UP95 Solute carrier family 12 member 4 chr16 Not Cancer Driver No 1 hippie 122 171 17 17 0
SLC39A7 SLC39A7 Q92504 Zinc transporter SLC39A7 chr6 Not Cancer Driver No 1 hippie 47 192 17 17 0
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 Census Yes 1 hippie 127 258 48 48 0
SNRNP200 SNRNP200 O75643 U5 small nuclear ribonucleoprotein 200 kDa helicase chr2 Not Cancer Driver No 1 hippie 237 270 37 37 11
SNX14 SNX14 Q9Y5W7 Sorting nexin-14 chr6 Not Cancer Driver No 1 hippie 94 99 12 12 0
SPP1 SPP1 P10451 Osteopontin chr4 Not Cancer Driver No 1 hippie 56 296 54 54 0
SPRR2G SPRR2G Q9BYE4 Small proline-rich protein 2G chr1 Not Cancer Driver No 1 hippie 23 0 0 0 0
SPTAN1_ENST00000372731 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 Not Cancer Driver No 1 hippie 315 980 114 114 0
SRP72_ENST00000642900 SRP72 O76094 Signal recognition particle subunit SRP72 chr4 Not Cancer Driver No 1 hippie 79 237 22 22 1
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 1 hippie 70 231 30 30 0
SUGP1 SUGP1 Q8IWZ8 SURP and G-patch domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 94 536 76 76 0
SUPT16H SUPT16H Q9Y5B9 FACT complex subunit SPT16 chr14 Not Cancer Driver No 1 hippie 147 301 44 44 0
SYCP1_ENST00000618516 SYCP1 Q15431 Synaptonemal complex protein 1 chr1 Not Cancer Driver No 1 hippie 207 602 124 124 0
SYNE1 SYNE1 Q8NF91 Nesprin-1 chr6 Not Cancer Driver No 1 hippie 1694 2530 530 530 2
SYT12_ENST00000527043 SYT12 Q8IV01 Synaptotagmin-12 chr11 Not Cancer Driver No 1 hippie 71 73 13 13 0
TENM3 TENM3 Q9P273 Teneurin-3 chr4 Not Cancer Driver No 1 hippie 618 484 112 112 0
TEPSIN TEPSIN Q96N21 AP-4 complex accessory subunit Tepsin chr17 Not Cancer Driver No 1 intact, hippie 54 321 37 37 0
THOC1 THOC1 Q96FV9 THO complex subunit 1 chr18 Not Cancer Driver No 1 hippie 55 280 26 26 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX Census Yes 1 hippie 7 44 7 7 0
TNN TNN Q9UQP3 Tenascin-N chr1 Not Cancer Driver No 1 hippie 426 637 231 231 0
TNNI1_ENST00000336092 TNNI1 P19237 Troponin I, slow skeletal muscle chr1 Not Cancer Driver No 1 hippie 34 72 8 8 0
TNNT1 TNNT1 P13805 Troponin T, slow skeletal muscle chr19 Not Cancer Driver No 1 hippie 61 240 55 55 0
TNNT3_ENST00000397301 TNNT3 P45378 Troponin T, fast skeletal muscle chr11 Not Cancer Driver No 1 hippie 59 246 52 52 2
TPM2 TPM2 P07951 Tropomyosin beta chain chr9 Not Cancer Driver No 1 hippie 39 232 35 35 15
TPM3 TPM3 P06753 Tropomyosin alpha-3 chain chr1 Census Yes 1 hippie 35 230 27 27 21
TRIM11 TRIM11 Q96F44 E3 ubiquitin-protein ligase TRIM11 chr1 Not Cancer Driver No 1 hippie 58 132 14 14 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 Not Cancer Driver No 1 hippie 85 49 7 7 0
TRPC3_ENST00000264811 TRPC3 Q13507 Short transient receptor potential channel 3 chr4 Not Cancer Driver No 1 hippie 200 23 2 2 1
TTN_ENST00000615779 TTN Q8WZ42 Titin chr2 Not Cancer Driver No 1 hippie 7917 12926 2861 2861 10
TTYH2 TTYH2 Q9BSA4 Protein tweety homolog 2 chr17 Not Cancer Driver No 1 hippie 63 68 19 19 0
TUBA1B TUBA1B P68363 Tubulin alpha-1B chain chr12 Not Cancer Driver No 1 hippie 41 52 9 9 0
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie 40 63 11 11 5
TUBG1 TUBG1 P23258 Tubulin gamma-1 chain chr17 Not Cancer Driver No 1 hippie 51 44 10 10 3
USP24 USP24 Q9UPU5 Ubiquitin carboxyl-terminal hydrolase 24 chr1 Not Cancer Driver No 1 hippie 229 430 27 27 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie 84 316 57 57 1
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VPS13D VPS13D Q5THJ4 Intermembrane lipid transfer protein VPS13D chr1 Not Cancer Driver No 1 hippie 501 973 118 118 8
WDR76 WDR76 Q9H967 WD repeat-containing protein 76 chr15 Not Cancer Driver No 1 hippie 60 288 33 33 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
ZC3H15 ZC3H15 Q8WU90 Zinc finger CCCH domain-containing protein 15 chr2 Not Cancer Driver No 1 hippie 58 281 44 44 0
ZCCHC8 ZCCHC8 Q6NZY4 Zinc finger CCHC domain-containing protein 8 chr12 Census Yes 1 hippie 81 503 56 56 1
ZFP41_ENST00000520584 ZFP41 Q8N8Y5 Zinc finger protein 41 homolog chr8 Not Cancer Driver No 2 intact, hippie, biogrid 33 100 17 17 0
ZMIZ1 ZMIZ1 Q9ULJ6 Zinc finger MIZ domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie 148 762 111 111 5
ZNF394 ZNF394 Q53GI3 Zinc finger protein 394 chr7 Not Cancer Driver No 1 hippie 74 329 47 47 0
ZRANB2 ZRANB2 O95218 Zinc finger Ran-binding domain-containing protein 2 chr1 Not Cancer Driver No 1 hippie 56 257 44 44 0
ZWINT ZWINT O95229 ZW10 interactor chr10 Not Cancer Driver No 1 hippie 65 168 44 44 0