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AGO3 ,AGO3 ,Q9H9G7
  • Uniprot Accession= Q9H9G7
  • Ensembl Transcript= ENST00000373191.8
  • Uniprot Name= AGO3
  • Name= Protein argonaute-3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 53
  • Number of Interaction partner in biogrid: 15
  • Number of Interaction partner in hippie: 131
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 intact, hippie 112 43 5 5 5
AGO1 AGO1 Q9UL18 Protein argonaute-1 chr1 Not Cancer Driver No 2 hippie, biogrid 126 87 11 11 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 2 intact, hippie 126 141 15 15 11
AGO3 AGO3 Q9H9G7 Protein argonaute-3 chr1 Not Cancer Driver No 1 hippie 110 143 19 19 0
AGO4 AGO4 Q9HCK5 Protein argonaute-4 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 100 183 24 24 0
ANKMY2 ANKMY2 Q8IV38 Ankyrin repeat and MYND domain-containing protein 2 chr7 Not Cancer Driver No 3 intact, hippie, biogrid 57 99 15 15 0
ANKRD17 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 Not Cancer Driver No 1 hippie 312 1790 221 221 9
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 Not Cancer Driver No 3 hippie, biogrid 126 316 31 31 1
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 138 404 59 59 0
AP3M1 AP3M1 Q9Y2T2 AP-3 complex subunit mu-1 chr10 Not Cancer Driver No 3 hippie, biogrid 45 19 1 1 0
AP3S1 AP3S1 Q92572 AP-3 complex subunit sigma-1 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 35 0 0 0 0
ATAD3B ATAD3B Q5T9A4 ATPase family AAA domain-containing protein 3B chr1 Not Cancer Driver No 1 hippie 84 243 19 19 0
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 Not Cancer Driver No 1 hippie 63 327 55 55 0
ATP4B ATP4B P51164 Potassium-transporting ATPase subunit beta chr13 Not Cancer Driver No 1 intact, hippie 35 2 0 0 0
ATP6V0D2 ATP6V0D2 Q8N8Y2 V-type proton ATPase subunit d 2 chr8 Not Cancer Driver No 1 intact, hippie 81 0 0 0 0
ATXN2_ENST00000550104 ATXN2 Q99700 Ataxin-2 chr12 Not Cancer Driver No 1 hippie 146 1228 134 134 0
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 intact, hippie 37 63 7 7 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 Not Cancer Driver No 1 hippie 47 79 19 19 1
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 Not Cancer Driver No 1 hippie 124 656 86 86 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 161 88 7 7 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 intact, hippie 71 95 12 12 0
CELF1_ENST00000358597 CELF1 Q92879 CUGBP Elav-like family member 1 chr11 Not Cancer Driver No 1 hippie 56 166 17 17 0
CEP85 CEP85 Q6P2H3 Centrosomal protein of 85 kDa chr1 Not Cancer Driver No 1 hippie 77 607 60 60 0
CIR1 CIR1 Q86X95 Corepressor interacting with RBPJ 1 chr2 Not Cancer Driver No 1 hippie 46 385 42 42 0
CLNS1A_ENST00000528364 CLNS1A P54105 Methylosome subunit pICln chr11 Not Cancer Driver No 1 hippie 19 170 13 13 0
CNOT2 CNOT2 Q9NZN8 CCR4-NOT transcription complex subunit 2 chr12 Not Cancer Driver No 1 hippie 84 354 66 66 0
CNOT6L CNOT6L Q96LI5 CCR4-NOT transcription complex subunit 6-like chr4 Not Cancer Driver No 1 hippie 58 37 3 3 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 Not Cancer Driver No 2 intact, hippie 31 21 1 1 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 Compendium Yes 1 hippie 42 30 0 0 0
CPEB1_ENST00000611031 CPEB1 Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 chr15 Not Cancer Driver No 1 intact, hippie 90 226 37 37 0
CPEB4 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 Not Cancer Driver No 1 hippie 85 443 54 54 0
CTIF_ENST00000256413 CTIF O43310 CBP80/20-dependent translation initiation factor chr18 Not Cancer Driver No 1 hippie 97 384 62 62 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
CUL5 CUL5 Q93034 Cullin-5 chr11 Not Cancer Driver No 1 intact, hippie 97 5 1 1 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
DAZL_ENST00000399444 DAZL Q92904 Deleted in azoospermia-like chr3 Not Cancer Driver No 1 hippie 28 128 12 12 0
DBT DBT P11182 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 64 81 11 11 3
DCP1A DCP1A Q9NPI6 mRNA-decapping enzyme 1A chr3 Not Cancer Driver No 1 hippie 46 382 31 31 0
DDOST_ENST00000375048 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 intact, hippie 34 13 3 3 1
DDX6 DDX6 P26196 Probable ATP-dependent RNA helicase DDX6 chr11 Census, Compendium Yes 1 hippie 44 129 7 7 5
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 Census, Compendium Yes 2 intact, hippie 264 362 45 45 4
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 intact, hippie 37 153 16 16 0
ECH1 ECH1 Q13011 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 35 23 2 2 0
ECI2 ECI2 O75521 Enoyl-CoA delta isomerase 2 chr6 Not Cancer Driver No 1 intact, hippie 52 70 8 8 0
EDC4 EDC4 Q6P2E9 Enhancer of mRNA-decapping protein 4 chr16 Not Cancer Driver No 1 hippie 144 702 69 69 0
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 intact, hippie 109 100 14 14 0
EIF3L EIF3L Q9Y262 Eukaryotic translation initiation factor 3 subunit L chr22 Not Cancer Driver No 1 intact, hippie 60 41 1 1 0
EIF4B_ENST00000262056 EIF4B P23588 Eukaryotic translation initiation factor 4B chr12 Not Cancer Driver No 1 intact, hippie 94 589 90 90 0
EIF4ENIF1 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 Not Cancer Driver No 1 hippie 116 899 101 101 0
FAM120C FAM120C Q9NX05 Constitutive coactivator of PPAR-gamma-like protein 2 chrX Not Cancer Driver No 1 hippie 162 508 77 77 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 Not Cancer Driver No 1 hippie, biogrid 75 243 38 38 1
FKBP5 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 70 150 20 20 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 intact, hippie 416 1456 214 214 28
FUBP3 FUBP3 Q96I24 Far upstream element-binding protein 3 chr9 Not Cancer Driver No 1 hippie 68 353 51 51 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 Not Cancer Driver No 1 hippie 68 388 42 42 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
HELZ_ENST00000358691 HELZ P42694 Probable helicase with zinc finger domain chr17 Not Cancer Driver No 1 hippie 234 873 110 110 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 hippie 39 206 19 19 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 5 intact, hippie, biogrid 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 2 intact, hippie 100 254 43 43 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 intact, hippie 67 283 26 26 2
IPO8 IPO8 O15397 Importin-8 chr12 Not Cancer Driver No 1 intact, hippie 130 111 13 13 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
LIMD1 LIMD1 Q9UGP4 LIM domain-containing protein 1 chr3 Not Cancer Driver No 1 intact, hippie 58 428 36 36 0
LONRF3 LONRF3 Q496Y0 LON peptidase N-terminal domain and RING finger protein 3 chrX Not Cancer Driver No 3 intact, hippie, biogrid 105 262 36 36 0
LSM14A_ENST00000433627 LSM14A Q8ND56 Protein LSM14 homolog A chr19 Census Yes 1 hippie 67 408 63 63 0
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie 78 508 66 66 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 22 24 1 1 0
MEX3B MEX3B Q6ZN04 RNA-binding protein MEX3B chr15 Not Cancer Driver No 1 hippie 85 437 64 64 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 45 145 16 16 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 310 1120 160 160 17
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 230 881 150 150 0
OTUD4_ENST00000447906 OTUD4 Q01804 OTU domain-containing protein 4 chr4 Not Cancer Driver No 1 hippie 148 788 120 120 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 1 hippie 100 317 55 55 0
PATL1 PATL1 Q86TB9 Protein PAT1 homolog 1 chr11 Not Cancer Driver No 1 hippie 79 499 49 49 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie 31 26 4 4 0
PHIP PHIP Q8WWQ0 PH-interacting protein chr6 Not Cancer Driver No 1 hippie 239 835 110 110 0
PPP5C PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 Not Cancer Driver No 2 intact, hippie 70 73 12 12 0
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 Census, Compendium Yes 1 hippie 39 66 11 11 17
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 intact, hippie 83 72 6 6 0
PRPF31 PRPF31 Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 chr19 Not Cancer Driver No 1 hippie 58 213 17 17 2
PRRC2A_ENST00000376007 PRRC2A P48634 Protein PRRC2A chr6 Not Cancer Driver No 1 hippie 253 2119 249 249 0
PSPC1_ENST00000619300 PSPC1 Q8WXF1 Paraspeckle component 1 chr13 Not Cancer Driver No 1 intact, hippie 97 367 81 81 0
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 1 hippie, biogrid 11 52 3 3 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 Not Cancer Driver No 1 hippie 150 640 77 77 3
QPCTL QPCTL Q9NXS2 Glutaminyl-peptide cyclotransferase-like protein chr19 Not Cancer Driver No 1 hippie 42 22 1 1 0
R3HDM2_ENST00000358907 R3HDM2 Q9Y2K5 R3H domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie 78 836 66 66 0
RANGRF RANGRF Q9HD47 Ran guanine nucleotide release factor chr17 Not Cancer Driver No 1 hippie, biogrid 10 42 5 5 0
RBM10_ENST00000377604 RBM10 P98175 RNA-binding protein 10 chrX Census, Compendium Yes 1 hippie 112 777 99 99 0
RBMS1 RBMS1 P29558 RNA-binding motif, single-stranded-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 55 243 36 36 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 158 796 115 115 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 1 intact, hippie 62 100 13 13 0
SF3B6 SF3B6 Q9Y3B4 Splicing factor 3B subunit 6 chr2 Not Cancer Driver No 1 intact, hippie 9 10 0 0 0
SLC22A2 SLC22A2 O15244 Solute carrier family 22 member 2 chr6 Not Cancer Driver No 1 intact, hippie 126 31 11 11 0
SLC25A3 SLC25A3 Q00325 Phosphate carrier protein, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie 49 32 4 4 1
SPIN1 SPIN1 Q9Y657 Spindlin-1 chr9 Not Cancer Driver No 1 hippie 31 132 18 18 0
SPSB4 SPSB4 Q96A44 SPRY domain-containing SOCS box protein 4 chr3 Not Cancer Driver No 1 hippie, biogrid 42 75 3 3 0
SPTAN1_ENST00000372731 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 Not Cancer Driver No 1 intact, hippie 315 980 114 114 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 Not Cancer Driver No 1 intact, hippie 311 869 123 123 0
STK38 STK38 Q15208 Serine/threonine-protein kinase 38 chr6 Not Cancer Driver No 1 hippie 57 77 6 6 0
SUN2_ENST00000405510 SUN2 Q9UH99 SUN domain-containing protein 2 chr22 Not Cancer Driver No 1 hippie 74 214 18 18 0
TAB1 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 1 intact, hippie 81 232 34 34 0
TARBP2 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 Not Cancer Driver No 1 hippie 45 203 22 22 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 Not Cancer Driver No 1 hippie, biogrid 188 320 58 58 0
TNRC6A TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 Not Cancer Driver No 4 intact, hippie 284 1830 265 265 0
TNRC6B TNRC6B Q9UPQ9 Trinucleotide repeat-containing gene 6B protein chr22 Not Cancer Driver No 4 intact, hippie 205 1735 195 195 0
TNRC6C_ENST00000301624 TNRC6C Q9HCJ0 Trinucleotide repeat-containing gene 6C protein chr17 Not Cancer Driver No 1 intact, hippie 170 1564 162 162 0
TOMM20 TOMM20 Q15388 Mitochondrial import receptor subunit TOM20 homolog chr1 Not Cancer Driver No 1 hippie 8 25 1 1 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 Not Cancer Driver No 1 intact, hippie 85 49 7 7 0
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 intact, hippie 59 52 11 11 8
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 intact, hippie 40 63 11 11 5
TUBB2A TUBB2A Q13885 Tubulin beta-2A chain chr6 Not Cancer Driver No 1 intact, hippie 44 70 13 13 2
TUBB4A TUBB4A P04350 Tubulin beta-4A chain chr19 Not Cancer Driver No 1 intact, hippie 91 61 16 16 2
TUBB4B TUBB4B P68371 Tubulin beta-4B chain chr9 Not Cancer Driver No 1 intact, hippie 52 65 11 11 2
UBAP2L UBAP2L Q14157 Ubiquitin-associated protein 2-like chr1 Not Cancer Driver No 1 hippie 129 1039 128 128 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 Not Cancer Driver No 1 intact, hippie 30 41 2 2 0
WTIP WTIP A6NIX2 Wilms tumor protein 1-interacting protein chr19 Not Cancer Driver No 1 intact, hippie 32 217 2 2 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
YTHDF1 YTHDF1 Q9BYJ9 YTH domain-containing family protein 1 chr20 Not Cancer Driver No 1 hippie 87 369 46 46 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 Not Cancer Driver No 1 hippie 67 376 44 44 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 Not Cancer Driver No 1 hippie 74 409 51 51 0
ZC3H7A_ENST00000355758 ZC3H7A Q8IWR0 Zinc finger CCCH domain-containing protein 7A chr16 Not Cancer Driver No 1 hippie 91 224 23 23 0
ZC3HAV1 ZC3HAV1 Q7Z2W4 Zinc finger CCCH-type antiviral protein 1 chr7 Not Cancer Driver No 1 hippie 142 344 63 63 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 Not Cancer Driver No 1 hippie 43 262 34 34 0
ZNF346_ENST00000358149 ZNF346 Q9UL40 Zinc finger protein 346 chr5 Not Cancer Driver No 1 hippie 29 175 17 17 0