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AGO1 ,AGO1 ,Q9UL18
  • Uniprot Accession= Q9UL18
  • Ensembl Transcript= ENST00000373204.5
  • Uniprot Name= AGO1
  • Name= Protein argonaute-1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 133
  • Number of Interaction partner in biogrid: 17
  • Number of Interaction partner in hippie: 266
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AGO1 AGO1 Q9UL18 Protein argonaute-1 chr1 Not Cancer Driver No 1 intact, hippie 126 87 11 11 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 3 intact, hippie, biogrid 126 141 15 15 11
AGO3 AGO3 Q9H9G7 Protein argonaute-3 chr1 Not Cancer Driver No 2 hippie, biogrid 110 143 19 19 0
AIP AIP O00170 AH receptor-interacting protein chr11 Not Cancer Driver No 2 hippie, biogrid 32 64 9 9 1
ANKRD17 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 Not Cancer Driver No 1 hippie 312 1790 221 221 9
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ATAD3B ATAD3B Q5T9A4 ATPase family AAA domain-containing protein 3B chr1 Not Cancer Driver No 1 hippie 84 243 19 19 0
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 Not Cancer Driver No 1 hippie 63 327 55 55 0
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 Census Yes 1 intact, hippie 115 115 16 16 6
ATP5F1C ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 Not Cancer Driver No 1 intact, hippie 39 11 0 0 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 Not Cancer Driver No 1 hippie 124 656 86 86 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 hippie 50 150 30 30 0
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 161 88 7 7 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CELF1_ENST00000358597 CELF1 Q92879 CUGBP Elav-like family member 1 chr11 Not Cancer Driver No 1 hippie 56 166 17 17 0
CEP85 CEP85 Q6P2H3 Centrosomal protein of 85 kDa chr1 Not Cancer Driver No 1 hippie 77 607 60 60 0
CNOT2 CNOT2 Q9NZN8 CCR4-NOT transcription complex subunit 2 chr12 Not Cancer Driver No 1 hippie 84 354 66 66 0
CNOT6L CNOT6L Q96LI5 CCR4-NOT transcription complex subunit 6-like chr4 Not Cancer Driver No 1 hippie 58 37 3 3 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 Not Cancer Driver No 1 intact, hippie 31 21 1 1 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 Compendium Yes 1 hippie 42 30 0 0 0
COPA_ENST00000241704 COPA P53621 Coatomer subunit alpha chr1 Not Cancer Driver No 1 intact, hippie 163 157 18 18 4
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
CPEB1_ENST00000611031 CPEB1 Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 chr15 Not Cancer Driver No 1 intact, hippie 90 226 37 37 0
CPEB4 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 Not Cancer Driver No 1 hippie 85 443 54 54 0
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CSDE1_ENST00000358528 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 Not Cancer Driver No 1 hippie 118 204 29 29 0
CTIF_ENST00000256413 CTIF O43310 CBP80/20-dependent translation initiation factor chr18 Not Cancer Driver No 1 hippie 97 384 62 62 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
CUL9 CUL9 Q8IWT3 Cullin-9 chr6 Not Cancer Driver No 1 hippie 321 633 73 73 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DAZL_ENST00000399444 DAZL Q92904 Deleted in azoospermia-like chr3 Not Cancer Driver No 1 hippie 28 128 12 12 0
DCAF10 DCAF10 Q5QP82 DDB1- and CUL4-associated factor 10 chr9 Not Cancer Driver No 1 hippie 50 201 11 11 0
DCP1A DCP1A Q9NPI6 mRNA-decapping enzyme 1A chr3 Not Cancer Driver No 1 hippie 46 382 31 31 0
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 Not Cancer Driver No 1 hippie 57 167 24 24 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 Not Cancer Driver No 1 intact 126 50 8 8 4
DDOST_ENST00000375048 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 intact, hippie 34 13 3 3 1
DDX18 DDX18 Q9NVP1 ATP-dependent RNA helicase DDX18 chr2 Not Cancer Driver No 1 hippie 111 239 36 36 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 Not Cancer Driver No 1 hippie 72 342 30 30 0
DDX39A DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie 44 37 2 2 0
DDX46_ENST00000354283 DDX46 Q7L014 Probable ATP-dependent RNA helicase DDX46 chr5 Not Cancer Driver No 1 hippie 120 510 72 72 0
DDX47 DDX47 Q9H0S4 Probable ATP-dependent RNA helicase DDX47 chr12 Not Cancer Driver No 1 intact, hippie 51 98 7 7 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 Census Yes 1 hippie 74 225 23 23 0
DDX50 DDX50 Q9BQ39 ATP-dependent RNA helicase DDX50 chr10 Not Cancer Driver No 1 hippie 86 274 30 30 0
DDX6 DDX6 P26196 Probable ATP-dependent RNA helicase DDX6 chr11 Census, Compendium Yes 1 hippie 44 129 7 7 5
DHX15 DHX15 O43143 ATP-dependent RNA helicase DHX15 chr4 Not Cancer Driver No 1 intact, hippie 110 180 30 30 0
DHX30 DHX30 Q7L2E3 ATP-dependent RNA helicase DHX30 chr3 Not Cancer Driver No 1 intact, hippie 165 260 40 40 6
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 Not Cancer Driver No 1 hippie 159 222 39 39 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 Compendium Yes 1 intact, hippie 182 331 42 42 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 Census, Compendium Yes 4 intact, hippie, biogrid 264 362 45 45 4
DIMT1 DIMT1 Q9UNQ2 Probable dimethyladenosine transferase chr5 Not Cancer Driver No 1 hippie 28 37 2 2 0
DLX4 DLX4 Q92988 Homeobox protein DLX-4 chr17 Not Cancer Driver No 1 intact, hippie 34 179 26 26 0
DNAJA2 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 intact, hippie 50 174 27 27 0
DNAJB11_ENST00000265028 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 Not Cancer Driver No 1 hippie 52 141 21 21 2
EBNA1BP2_ENST00000236051 EBNA1BP2 Q99848 Probable rRNA-processing protein EBP2 chr1 Not Cancer Driver No 1 hippie 38 254 34 34 0
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 intact, hippie 109 100 14 14 0
EIF2B2 EIF2B2 P49770 Translation initiation factor eIF-2B subunit beta chr14 Not Cancer Driver No 1 hippie 40 83 11 11 9
EIF2B4_ENST00000347454 EIF2B4 Q9UI10 Translation initiation factor eIF-2B subunit delta chr2 Not Cancer Driver No 1 intact, hippie 57 212 29 29 7
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 Not Cancer Driver No 1 hippie 50 57 6 6 1
EIF4ENIF1 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 Not Cancer Driver No 1 hippie 116 899 101 101 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 intact, hippie 69 43 5 5 0
EPRS EPRS1 P07814 Bifunctional glutamate/proline--tRNA ligase chr1 Not Cancer Driver No 1 intact 204 372 62 62 1
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FAM120C FAM120C Q9NX05 Constitutive coactivator of PPAR-gamma-like protein 2 chrX Not Cancer Driver No 1 hippie 162 508 77 77 0
FBXL13_ENST00000436908 FBXL13 Q8NEE6 Dynein regulatory complex subunit 6 chr7 Not Cancer Driver No 1 intact, hippie 103 41 5 5 0
FKBP5 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 70 150 20 20 0
FLG2 FLG2 Q5D862 Filaggrin-2 chr1 Not Cancer Driver No 1 intact, hippie 613 2252 577 577 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX Not Cancer Driver No 1 intact, hippie 124 327 70 70 3
FUBP3 FUBP3 Q96I24 Far upstream element-binding protein 3 chr9 Not Cancer Driver No 1 hippie 68 353 51 51 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 hippie 88 312 53 53 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 Not Cancer Driver No 1 intact, hippie 68 388 42 42 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 11 2 1 1 0
GEMIN2 GEMIN2 O14893 Gem-associated protein 2 chr14 Not Cancer Driver No 1 intact, hippie 39 99 6 6 0
GEMIN4 GEMIN4 P57678 Gem-associated protein 4 chr17 Not Cancer Driver No 1 intact, hippie 101 24 1 1 0
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 Not Cancer Driver No 1 hippie 56 257 21 21 0
GPRASP2 GPRASP2 Q96D09 G-protein coupled receptor-associated sorting protein 2 chrX Not Cancer Driver No 1 hippie 133 506 81 81 1
GTF3C1 GTF3C1 Q12789 General transcription factor 3C polypeptide 1 chr16 Not Cancer Driver No 1 intact, hippie 323 735 114 114 0
GTF3C4 GTF3C4 Q9UKN8 General transcription factor 3C polypeptide 4 chr9 Not Cancer Driver No 1 intact, hippie 76 164 13 13 0
HELZ_ENST00000358691 HELZ P42694 Probable helicase with zinc finger domain chr17 Not Cancer Driver No 1 hippie 234 873 110 110 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie 37 77 9 9 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 intact, hippie 70 290 58 58 4
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 Not Cancer Driver No 1 intact, hippie 42 227 35 35 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 hippie 39 206 19 19 0
HNRNPF_ENST00000356053 HNRNPF P52597 Heterogeneous nuclear ribonucleoprotein F chr10 Not Cancer Driver No 1 intact, hippie 65 105 18 18 0
HNRNPH2 HNRNPH2 P55795 Heterogeneous nuclear ribonucleoprotein H2 chrX Not Cancer Driver No 1 intact, hippie 73 168 34 34 3
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 intact, hippie 77 504 45 45 0
HNRNPUL1 HNRNPUL1 Q9BUJ2 Heterogeneous nuclear ribonucleoprotein U-like protein 1 chr19 Not Cancer Driver No 1 hippie 100 535 49 49 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 2 hippie, biogrid 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 3 intact, hippie, biogrid 100 254 43 43 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 61 82 6 6 2
IGF2BP1 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 Not Cancer Driver No 1 hippie 141 298 80 80 0
IGF2BP2_ENST00000382199 IGF2BP2 Q9Y6M1 Insulin-like growth factor 2 mRNA-binding protein 2 chr3 Census Yes 1 hippie 68 237 31 31 0
IGF2BP3 IGF2BP3 O00425 Insulin-like growth factor 2 mRNA-binding protein 3 chr7 Not Cancer Driver No 1 intact, hippie 79 264 40 40 0
ILF2 ILF2 Q12905 Interleukin enhancer-binding factor 2 chr1 Not Cancer Driver No 1 hippie 36 92 9 9 0
ILF3_ENST00000590261 ILF3 Q12906 Interleukin enhancer-binding factor 3 chr19 Not Cancer Driver No 1 intact, hippie 103 674 82 82 0
IMMT IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie 97 400 50 50 0
IPO8 IPO8 O15397 Importin-8 chr12 Not Cancer Driver No 1 intact, hippie 130 111 13 13 0
IPO9 IPO9 Q96P70 Importin-9 chr1 Not Cancer Driver No 1 hippie 145 102 22 22 0
KHDRBS1 KHDRBS1 Q07666 KH domain-containing, RNA-binding, signal transduction-associated protein 1 chr1 Not Cancer Driver No 1 hippie 53 362 43 43 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KRR1 KRR1 Q13601 KRR1 small subunit processome component homolog chr12 Not Cancer Driver No 1 hippie 37 194 23 23 0
LAS1L LAS1L Q9Y4W2 Ribosomal biogenesis protein LAS1L chrX Not Cancer Driver No 1 intact, hippie 100 279 49 49 0
LIMD1 LIMD1 Q9UGP4 LIM domain-containing protein 1 chr3 Not Cancer Driver No 1 intact, hippie 58 428 36 36 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 intact, hippie 33 122 15 15 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 2 intact, hippie 519 90 17 17 23
LSM14A_ENST00000433627 LSM14A Q8ND56 Protein LSM14 homolog A chr19 Census Yes 1 hippie 67 408 63 63 0
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 Not Cancer Driver No 1 intact, hippie 50 249 31 31 0
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie 78 508 66 66 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 22 24 1 1 0
MATR3_ENST00000509990 MATR3 P43243 Matrin-3 chr5 Not Cancer Driver No 1 hippie 98 611 68 68 3
MCF2L_ENST00000375608 MCF2L O15068 Guanine nucleotide exchange factor DBS chr13 Not Cancer Driver No 1 hippie 173 410 54 54 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie 76 446 42 42 0
MEX3B MEX3B Q6ZN04 RNA-binding protein MEX3B chr15 Not Cancer Driver No 1 hippie 85 437 64 64 0
MEX3D MEX3D Q86XN8 RNA-binding protein MEX3D chr19 Not Cancer Driver No 1 hippie 35 501 24 24 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 45 145 16 16 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MRPS15 MRPS15 P82914 28S ribosomal protein S15, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 35 72 7 7 0
MRPS16 MRPS16 Q9Y3D3 28S ribosomal protein S16, mitochondrial chr10 Not Cancer Driver No 1 intact, hippie 7 29 2 2 0
MRPS2 MRPS2 Q9Y399 28S ribosomal protein S2, mitochondrial chr9 Not Cancer Driver No 1 intact 32 57 6 6 3
MRPS22 MRPS22 P82650 28S ribosomal protein S22, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 51 65 8 8 1
MRPS23 MRPS23 Q9Y3D9 28S ribosomal protein S23, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 21 58 6 6 1
MRPS27_ENST00000261413 MRPS27 Q92552 28S ribosomal protein S27, mitochondrial chr5 Not Cancer Driver No 1 intact, hippie 46 51 7 7 0
MRPS5 MRPS5 P82675 28S ribosomal protein S5, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 52 157 20 20 0
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 Not Cancer Driver No 1 intact, hippie 144 463 47 47 0
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 Not Cancer Driver No 1 intact, hippie 109 142 18 18 0
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 Not Cancer Driver No 1 hippie 88 89 8 8 0
NCL NCL P19338 Nucleolin chr2 Not Cancer Driver No 1 intact, hippie 85 569 68 68 0
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 Not Cancer Driver No 1 hippie 300 71 20 20 9
NOP56 NOP56 O00567 Nucleolar protein 56 chr20 Not Cancer Driver No 1 intact, hippie 83 191 34 34 0
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 intact, hippie 29 249 22 22 0
NUDCD1 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 75 38 4 4 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OTUD7B OTUD7B Q6GQQ9 OTU domain-containing protein 7B chr1 Not Cancer Driver No 1 hippie 124 537 87 87 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 2 intact, hippie 100 317 55 55 0
PABPC3 PABPC3 Q9H361 Polyadenylate-binding protein 3 chr13 Not Cancer Driver No 1 hippie 154 286 68 68 0
PAIP2_ENST00000265192 PAIP2 Q9BPZ3 Polyadenylate-binding protein-interacting protein 2 chr5 Not Cancer Driver No 1 hippie 11 88 10 10 0
PAK1IP1 PAK1IP1 Q9NWT1 p21-activated protein kinase-interacting protein 1 chr6 Not Cancer Driver No 1 intact, hippie 38 83 6 6 0
PARP2 PARP2 Q9UGN5 Poly [ADP-ribose] polymerase 2 chr14 Not Cancer Driver No 1 intact, hippie 74 172 23 23 0
PASK_ENST00000234040 PASK Q96RG2 PAS domain-containing serine/threonine-protein kinase chr2 Not Cancer Driver No 1 hippie 181 412 62 62 0
PATL1 PATL1 Q86TB9 Protein PAT1 homolog 1 chr11 Not Cancer Driver No 1 hippie 79 499 49 49 0
PCBP2_ENST00000439930 PCBP2 Q15366 Poly(rC)-binding protein 2 chr12 Not Cancer Driver No 1 intact, hippie 40 200 24 24 0
PDCD1 PDCD1 Q15116 Programmed cell death protein 1 chr2 Not Cancer Driver No 1 intact, hippie 56 141 37 37 0
PELP1_ENST00000574876 PELP1 Q8IZL8 Proline-, glutamic acid- and leucine-rich protein 1 chr17 Not Cancer Driver No 1 hippie 134 610 82 82 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie 31 26 4 4 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 Not Cancer Driver No 1 intact 37 4 1 1 0
PHF5A PHF5A Q7RTV0 PHD finger-like domain-containing protein 5A chr22 Not Cancer Driver No 1 hippie 20 0 0 0 0
POLR1A POLR1A O95602 DNA-directed RNA polymerase I subunit RPA1 chr2 Not Cancer Driver No 1 intact, hippie 208 361 64 64 2
POLR1C POLR1C O15160 DNA-directed RNA polymerases I and III subunit RPAC1 chr6 Not Cancer Driver No 1 hippie 34 28 3 3 13
POLR2A POLR2A P24928-2 Isoform 2 of DNA-directed RNA polymerase II subunit RPB1 chr17 Census Yes 1 hippie 56 230 20 20 0
PPP5C PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 Not Cancer Driver No 1 hippie 70 73 12 12 0
PPP6R1_ENST00000587283 PPP6R1 Q9UPN7 Serine/threonine-protein phosphatase 6 regulatory subunit 1 chr19 Not Cancer Driver No 1 hippie 82 471 47 47 0
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 intact, hippie 83 72 6 6 0
PRNP PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 36 115 7 7 18
PRRC2A_ENST00000376007 PRRC2A P48634 Protein PRRC2A chr6 Not Cancer Driver No 1 hippie 253 2119 249 249 0
PTCD3 PTCD3 Q96EY7 Pentatricopeptide repeat domain-containing protein 3, mitochondrial chr2 Not Cancer Driver No 1 hippie 69 77 4 4 0
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 1 hippie, biogrid 11 52 3 3 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 Not Cancer Driver No 1 hippie 150 640 77 77 3
R3HDM2_ENST00000358907 R3HDM2 Q9Y2K5 R3H domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie 78 836 66 66 0
RBMS1 RBMS1 P29558 RNA-binding motif, single-stranded-interacting protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 55 243 36 36 0
RBMS2 RBMS2 Q15434 RNA-binding motif, single-stranded-interacting protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 53 265 38 38 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 158 796 115 115 0
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 75 400 48 48 0
RPL10_ENST00000369817 RPL10 P27635 60S ribosomal protein L10 chrX Census, Compendium Yes 1 intact, hippie 46 9 3 3 4
RPL11 RPL11 P62913 60S ribosomal protein L11 chr1 Not Cancer Driver No 1 intact, hippie 27 12 1 1 1
RPL12 RPL12 P30050 60S ribosomal protein L12 chr9 Not Cancer Driver No 1 intact, hippie 13 75 6 6 0
RPL13A RPL13A P40429 60S ribosomal protein L13a chr19 Not Cancer Driver No 1 hippie 27 33 2 2 0
RPL13_ENST00000393099 RPL13 P26373 60S ribosomal protein L13 chr16 Not Cancer Driver No 1 intact, hippie 14 160 11 11 1
RPL14_ENST00000396203 RPL14 P50914 60S ribosomal protein L14 chr3 Not Cancer Driver No 1 intact, hippie 21 129 13 13 0
RPL15_ENST00000413699 RPL15 P61313 60S ribosomal protein L15 chr3 Not Cancer Driver No 1 intact, hippie 18 84 9 9 0
RPL17_ENST00000579248 RPL17 P18621 60S ribosomal protein L17 chr18 Not Cancer Driver No 1 hippie 26 97 14 14 0
RPL18 RPL18 Q07020 60S ribosomal protein L18 chr19 Not Cancer Driver No 1 intact, hippie 16 98 6 6 0
RPL18A RPL18A Q02543 60S ribosomal protein L18a chr19 Not Cancer Driver No 1 intact, hippie 28 25 4 4 0
RPL19 RPL19 P84098 60S ribosomal protein L19 chr17 Not Cancer Driver No 1 intact, hippie 30 121 21 21 0
RPL21_ENST00000326092 RPL21 P46778 60S ribosomal protein L21 chr13 Not Cancer Driver No 1 intact, hippie 15 103 11 11 1
RPL23A RPL23A P62750 60S ribosomal protein L23a chr17 Not Cancer Driver No 1 intact, hippie 21 70 13 13 0
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 Not Cancer Driver No 1 intact, hippie 14 29 4 4 0
RPL24 RPL24 P83731 60S ribosomal protein L24 chr3 Not Cancer Driver No 1 intact, hippie 19 105 14 14 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 Not Cancer Driver No 1 intact, hippie 16 114 13 13 0
RPL27A RPL27A P46776 60S ribosomal protein L27a chr11 Not Cancer Driver No 1 intact, hippie 7 56 2 2 0
RPL28_ENST00000559463 RPL28 P46779 60S ribosomal protein L28 chr19 Not Cancer Driver No 1 intact, hippie 29 115 24 24 0
RPL29_ENST00000475248 RPL29 P47914 60S ribosomal protein L29 chr3 Not Cancer Driver No 1 hippie 9 159 9 9 0
RPL31_ENST00000264258 RPL31 P62899 60S ribosomal protein L31 chr2 Not Cancer Driver No 1 intact, hippie 19 69 14 14 0
RPL35 RPL35 P42766 60S ribosomal protein L35 chr9 Not Cancer Driver No 1 intact, hippie 12 65 9 9 0
RPL35A RPL35A P18077 60S ribosomal protein L35a chr3 Not Cancer Driver No 1 intact, hippie 9 25 0 0 1
RPL37A RPL37A P61513 60S ribosomal protein L37a chr2 Not Cancer Driver No 1 intact, hippie 4 0 0 0 0
RPL38_ENST00000439590 RPL38 P63173 60S ribosomal protein L38 chr17 Not Cancer Driver No 1 intact, hippie 2 9 0 0 0
RPL4 RPL4 P36578 60S ribosomal protein L4 chr15 Not Cancer Driver No 1 intact, hippie 49 222 31 31 0
RPL6 RPL6 Q02878 60S ribosomal protein L6 chr12 Not Cancer Driver No 1 intact, hippie 41 159 24 24 0
RPL7 RPL7 P18124 60S ribosomal protein L7 chr8 Not Cancer Driver No 1 intact, hippie 24 40 4 4 0
RPL7A RPL7A P62424 60S ribosomal protein L7a chr9 Not Cancer Driver No 1 intact, hippie 27 100 5 5 0
RPL8_ENST00000528957 RPL8 P62917 60S ribosomal protein L8 chr8 Not Cancer Driver No 1 intact, hippie 32 115 17 17 0
RPLP0_ENST00000228306 RPLP0 P05388 60S acidic ribosomal protein P0 chr12 Not Cancer Driver No 1 intact, hippie 44 36 4 4 0
RPS13 RPS13 P62277 40S ribosomal protein S13 chr11 Not Cancer Driver No 1 intact, hippie 19 18 5 5 0
RPS15A_ENST00000565420 RPS15A P62244 40S ribosomal protein S15a chr16 Not Cancer Driver No 1 intact, hippie 6 4 0 0 0
RPS18 RPS18 P62269 40S ribosomal protein S18 chr6 Not Cancer Driver No 1 intact, hippie 28 27 8 8 0
RPS2 RPS2 P15880 40S ribosomal protein S2 chr16 Not Cancer Driver No 1 intact, hippie 34 85 14 14 0
RPS23 RPS23 P62266 40S ribosomal protein S23 chr5 Not Cancer Driver No 1 intact, hippie 8 35 1 1 2
RPS26_ENST00000646449 RPS26 P62854 40S ribosomal protein S26 chr12 Not Cancer Driver No 1 intact, hippie 9 52 5 5 2
RPS27L RPS27L Q71UM5 40S ribosomal protein S27-like chr15 Not Cancer Driver No 1 intact, hippie 4 22 2 2 0
RPS3A RPS3A P61247 40S ribosomal protein S3a chr4 Compendium Yes 1 intact, hippie 21 85 5 5 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 Not Cancer Driver No 1 intact, hippie 22 48 4 4 0
RPS4X RPS4X P62701 40S ribosomal protein S4, X isoform chrX Not Cancer Driver No 1 intact, hippie 32 35 6 6 0
RPS5_ENST00000601521 RPS5 P46782 40S ribosomal protein S5 chr19 Not Cancer Driver No 1 intact, hippie 38 40 8 8 0
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 Not Cancer Driver No 1 intact, hippie 38 150 25 25 0
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 Not Cancer Driver No 1 intact, hippie 29 39 7 7 0
RPS8 RPS8 P62241 40S ribosomal protein S8 chr1 Not Cancer Driver No 1 intact 23 81 7 7 0
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 Not Cancer Driver No 1 intact, hippie 23 34 5 5 0
RSL1D1 RSL1D1 O76021 Ribosomal L1 domain-containing protein 1 chr16 Not Cancer Driver No 1 intact, hippie 61 275 33 33 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 1 intact, hippie 62 100 13 13 0
SAMD4B SAMD4B Q5PRF9 Protein Smaug homolog 2 chr19 Not Cancer Driver No 1 hippie 79 467 57 57 0
SART3 SART3 Q15020 Squamous cell carcinoma antigen recognized by T-cells 3 chr12 Not Cancer Driver No 1 hippie 101 404 45 45 0
SF3B1 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 Census, Compendium Yes 1 hippie 244 477 80 80 0
SF3B2 SF3B2 Q13435 Splicing factor 3B subunit 2 chr11 Not Cancer Driver No 1 intact, hippie 110 804 105 105 0
SF3B3 SF3B3 Q15393 Splicing factor 3B subunit 3 chr16 Not Cancer Driver No 1 intact, hippie 154 145 19 19 0
SF3B6 SF3B6 Q9Y3B4 Splicing factor 3B subunit 6 chr2 Not Cancer Driver No 1 intact, hippie 9 10 0 0 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 Not Cancer Driver No 1 hippie 70 435 31 31 0
SLC25A13_ENST00000265631 SLC25A13 Q9UJS0 Calcium-binding mitochondrial carrier protein Aralar2 chr7 Not Cancer Driver No 1 intact, hippie 111 23 2 2 1
SLC25A3 SLC25A3 Q00325 Phosphate carrier protein, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie 49 32 4 4 1
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 1 intact, hippie 41 0 0 0 0
SLC25A6 SLC25A6 P12236 ADP/ATP translocase 3 chrX Not Cancer Driver No 1 intact, hippie 41 0 0 0 0
SMAP2 SMAP2 Q8WU79 Stromal membrane-associated protein 2 chr1 Not Cancer Driver No 1 hippie 50 214 30 30 0
SMG6 SMG6 Q86US8 Telomerase-binding protein EST1A chr17 Not Cancer Driver No 1 hippie 166 751 97 97 0
SNRNP200 SNRNP200 O75643 U5 small nuclear ribonucleoprotein 200 kDa helicase chr2 Not Cancer Driver No 1 intact, hippie 237 270 37 37 11
SRSF10 SRSF10 O75494 Serine/arginine-rich splicing factor 10 chr1 Not Cancer Driver No 1 hippie 2 192 1 1 0
SSR1 SSR1 P43307 Translocon-associated protein subunit alpha chr6 Not Cancer Driver No 1 hippie 26 114 10 10 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 2 hippie, biogrid 35 112 14 14 12
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 Not Cancer Driver No 1 hippie 93 285 39 39 0
SYNE1 SYNE1 Q8NF91 Nesprin-1 chr6 Not Cancer Driver No 1 intact, hippie 1694 2530 530 530 2
TARBP2 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 Not Cancer Driver No 2 hippie, biogrid 45 203 22 22 0
TAX1BP1 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 Not Cancer Driver No 1 hippie 78 429 50 50 0
TBL2 TBL2 Q9Y4P3 Transducin beta-like protein 2 chr7 Not Cancer Driver No 1 intact, hippie 68 115 13 13 0
TCF25 TCF25 Q9BQ70 Transcription factor 25 chr16 Not Cancer Driver No 1 hippie 82 280 35 35 0
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 Not Cancer Driver No 1 hippie 54 55 10 10 0
TDRD3_ENST00000196169 TDRD3 Q9H7E2 Tudor domain-containing protein 3 chr13 Not Cancer Driver No 1 hippie 97 518 77 77 0
TEX10 TEX10 Q9NXF1 Testis-expressed protein 10 chr9 Not Cancer Driver No 1 intact, hippie 115 103 12 12 0
TMEM33_ENST00000325094 TMEM33 P57088 Transmembrane protein 33 chr4 Not Cancer Driver No 1 hippie 24 6 0 0 0
TNRC6A TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 Not Cancer Driver No 5 intact, hippie, biogrid 284 1830 265 265 0
TNRC6B TNRC6B Q9UPQ9 Trinucleotide repeat-containing gene 6B protein chr22 Not Cancer Driver No 3 intact, hippie 205 1735 195 195 0
TNRC6C_ENST00000301624 TNRC6C Q9HCJ0 Trinucleotide repeat-containing gene 6C protein chr17 Not Cancer Driver No 2 intact, hippie, biogrid 170 1564 162 162 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 Census, Compendium Yes 1 hippie 229 398 143 143 28
TP73 TP73 O15350 Tumor protein p73 chr1 Not Cancer Driver No 1 hippie 82 443 55 55 0
TRMT13 TRMT13 Q9NUP7 tRNA:m(4)X modification enzyme TRM13 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 69 177 31 31 0
UBAP2L UBAP2L Q14157 Ubiquitin-associated protein 2-like chr1 Not Cancer Driver No 1 hippie 129 1039 128 128 0
UBC UBC P0CG48 Polyubiquitin-C chr12 Not Cancer Driver No 1 intact 97 312 53 53 0
UNK UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 79 511 46 46 0
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 Not Cancer Driver No 1 intact, hippie 146 329 36 36 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WDCP WDCP Q9H6R7 WD repeat and coiled-coil-containing protein chr2 Census Yes 1 hippie 77 126 9 9 0
WDR18 WDR18 Q9BV38 WD repeat-containing protein 18 chr19 Not Cancer Driver No 1 intact, hippie 38 60 2 2 0
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 Not Cancer Driver No 1 intact, hippie 30 41 2 2 0
WTIP WTIP A6NIX2 Wilms tumor protein 1-interacting protein chr19 Not Cancer Driver No 1 intact, hippie 32 217 2 2 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 intact, hippie 66 140 12 12 0
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 Not Cancer Driver No 1 hippie 213 577 65 65 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 41 312 41 41 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 Not Cancer Driver No 1 hippie, biogrid 49 359 47 47 0
YTHDF1 YTHDF1 Q9BYJ9 YTH domain-containing family protein 1 chr20 Not Cancer Driver No 1 hippie 87 369 46 46 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 Not Cancer Driver No 1 hippie 67 376 44 44 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 Not Cancer Driver No 1 hippie 74 409 51 51 0
ZBP1 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 Not Cancer Driver No 1 intact, hippie 97 385 80 80 0
ZC3H7A_ENST00000355758 ZC3H7A Q8IWR0 Zinc finger CCCH domain-containing protein 7A chr16 Not Cancer Driver No 1 hippie 91 224 23 23 0
ZC3HAV1 ZC3HAV1 Q7Z2W4 Zinc finger CCCH-type antiviral protein 1 chr7 Not Cancer Driver No 1 hippie 142 344 63 63 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 Not Cancer Driver No 1 hippie 43 262 34 34 0
ZNF326 ZNF326 Q5BKZ1 DBIRD complex subunit ZNF326 chr1 Not Cancer Driver No 1 intact, hippie 64 490 53 53 0