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AGL_ENST00000361915 ,AGL ,P35573
  • Uniprot Accession= P35573
  • Ensembl Transcript= ENST00000361915.7
  • Uniprot Name= AGL
  • Name= Glycogen debranching enzyme
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 18
  • Number of Interaction partner in biogrid: 31
  • Number of Interaction partner in hippie: 85
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AHSA1 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 1 hippie 46 146 17 17 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 Not Cancer Driver No 1 hippie 67 292 31 31 1
ARIH2 ARIH2 O95376 E3 ubiquitin-protein ligase ARIH2 chr3 Not Cancer Driver No 1 hippie 64 85 11 11 0
ASB15_ENST00000451215 ASB15 Q8WXK1 Ankyrin repeat and SOCS box protein 15 chr7 Not Cancer Driver No 1 hippie 118 32 6 6 0
ASB3 ASB3 Q9Y575 Ankyrin repeat and SOCS box protein 3 chr2 Not Cancer Driver No 1 hippie 71 0 0 0 0
ASPSCR1_ENST00000306739 ASPSCR1 Q9BZE9 Tether containing UBX domain for GLUT4 chr17 Census Yes 1 hippie, biogrid 72 298 49 49 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie, biogrid 51 63 8 8 0
BCAT1_ENST00000261192 BCAT1 P54687 Branched-chain-amino-acid aminotransferase, cytosolic chr12 Not Cancer Driver No 1 hippie 67 8 2 2 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
CAT CAT P04040 Catalase chr11 Not Cancer Driver No 1 hippie, biogrid 70 176 18 18 0
CBX1_ENST00000225603 CBX1 P83916 Chromobox protein homolog 1 chr17 Not Cancer Driver No 1 intact, hippie 31 154 25 25 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 48 5 1 1 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 intact, hippie 151 65 9 9 0
CUL2_ENST00000374748 CUL2 Q13617 Cullin-2 chr10 Not Cancer Driver No 1 intact, hippie 87 66 3 3 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 intact, hippie 138 207 38 38 2
CUL5 CUL5 Q93034 Cullin-5 chr11 Not Cancer Driver No 1 intact, hippie 97 5 1 1 0
DCUN1D1 DCUN1D1 Q96GG9 DCN1-like protein 1 chr3 Not Cancer Driver No 1 intact, hippie 34 13 0 0 0
DERA DERA Q9Y315 Deoxyribose-phosphate aldolase chr12 Not Cancer Driver No 1 hippie, biogrid 33 2 0 0 0
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 107 59 6 6 2
EMC2 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 hippie 48 29 3 3 0
FASTK FASTK Q14296 Fas-activated serine/threonine kinase chr7 Not Cancer Driver No 1 intact, hippie, biogrid 65 143 12 12 0
FBXO32 FBXO32 Q969P5 F-box only protein 32 chr8 Not Cancer Driver No 1 hippie 54 0 0 0 0
FKBP1A FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A chr20 Not Cancer Driver No 1 hippie, biogrid 15 39 7 7 0
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 Not Cancer Driver No 1 hippie, biogrid 10 58 4 4 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 Compendium Yes 1 intact, hippie 70 258 34 34 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 11 2 1 1 0
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 Not Cancer Driver No 1 hippie, biogrid 88 73 14 14 107
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 Not Cancer Driver No 1 hippie, biogrid 73 167 18 18 3
GLO1 GLO1 Q04760 Lactoylglutathione lyase chr6 Not Cancer Driver No 1 hippie, biogrid 24 46 7 7 0
GRHPR GRHPR Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase chr9 Not Cancer Driver No 1 hippie, biogrid 31 36 4 4 0
GYG2 GYG2 O15488 Glycogenin-2 chrX Not Cancer Driver No 1 hippie, biogrid 70 217 28 28 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
KHK_ENST00000260598 KHK P50053 Ketohexokinase chr2 Not Cancer Driver No 1 hippie, biogrid 38 42 4 4 2
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 Not Cancer Driver No 1 hippie 108 16 3 3 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact 519 90 17 17 23
MAN2B1 MAN2B1 O00754 Lysosomal alpha-mannosidase chr19 Not Cancer Driver No 1 hippie, biogrid 139 145 21 21 40
MAP3K6 MAP3K6 O95382 Mitogen-activated protein kinase kinase kinase 6 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 108 390 31 31 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 hippie, biogrid 92 376 49 49 1
MCFD2_ENST00000409973 MCFD2 Q8NI22 Multiple coagulation factor deficiency protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 16 90 11 11 4
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie 76 446 42 42 0
MMGT1 MMGT1 Q8N4V1 ER membrane protein complex subunit 5 chrX Not Cancer Driver No 1 hippie 24 17 4 4 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
NAXD NAXD Q8IW45-2 Isoform 2 of ATP-dependent (S)-NAD(P)H-hydrate dehydratase chr13 Not Cancer Driver No 1 hippie 48 111 11 11 0
NHLRC1 NHLRC1 Q6VVB1 E3 ubiquitin-protein ligase NHLRC1 chr6 Not Cancer Driver No 1 hippie 66 18 3 3 22
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PHKG2 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 Not Cancer Driver No 1 hippie, biogrid 48 50 6 6 4
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie, biogrid 78 58 13 13 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 Not Cancer Driver No 1 intact, hippie 128 98 26 26 0
PRKAB1 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 Not Cancer Driver No 1 hippie 39 124 13 13 0
PRKAB2 PRKAB2 O43741 5'-AMP-activated protein kinase subunit beta-2 chr1 Not Cancer Driver No 1 intact, hippie 31 110 12 12 0
PRKAG1_ENST00000548065 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 35 25 2 2 0
PRNP PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 36 115 7 7 18
PSMB6 PSMB6 P28072 Proteasome subunit beta type-6 chr17 Not Cancer Driver No 1 hippie, biogrid 19 22 1 1 0
PUS1 PUS1 Q9Y606 Pseudouridylate synthase 1 homolog chr12 Not Cancer Driver No 1 hippie 48 157 18 18 1
PYGB PYGB P11216 Glycogen phosphorylase, brain form chr20 Not Cancer Driver No 1 hippie, biogrid 118 29 5 5 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 Not Cancer Driver No 1 hippie, biogrid 20 14 1 1 0
RASSF5 RASSF5 Q8WWW0 Ras association domain-containing protein 5 chr1 Not Cancer Driver No 1 hippie 37 183 11 11 0
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 167 220 28 28 0
RNF126 RNF126 Q9BV68 E3 ubiquitin-protein ligase RNF126 chr19 Not Cancer Driver No 1 hippie 33 182 22 22 0
SDHB SDHB P21912 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial chr1 Census Yes 1 hippie, biogrid 37 17 3 3 23
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 Not Cancer Driver No 1 hippie 62 0 0 0 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 Not Cancer Driver No 1 hippie 41 82 10 10 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 intact, hippie 97 111 19 19 5
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 Not Cancer Driver No 1 hippie 136 680 101 101 0
SPATA20_ENST00000356488 SPATA20 Q8TB22 Spermatogenesis-associated protein 20 chr17 Not Cancer Driver No 1 hippie, biogrid 101 162 19 19 0
STBD1 STBD1 O95210 Starch-binding domain-containing protein 1 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 47 229 31 31 0
SULT1E1 SULT1E1 P49888 Sulfotransferase 1E1 chr4 Not Cancer Driver No 1 hippie, biogrid 76 15 5 5 0
TKFC TKFC Q3LXA3 Triokinase/FMN cyclase chr11 Not Cancer Driver No 1 hippie 66 91 14 14 2
TNS2_ENST00000314250 TNS2 Q63HR2 Tensin-2 chr12 Not Cancer Driver No 1 hippie 132 799 63 63 0
TOM1L2 TOM1L2 Q6ZVM7 TOM1-like protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 57 335 37 37 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
USP5 USP5 P45974 Ubiquitin carboxyl-terminal hydrolase 5 chr12 Not Cancer Driver No 1 hippie, biogrid 117 262 38 38 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 Not Cancer Driver No 1 intact, hippie 89 243 28 28 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VPS25 VPS25 Q9BRG1 Vacuolar protein-sorting-associated protein 25 chr17 Not Cancer Driver No 1 hippie 16 10 0 0 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 67 376 44 44 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0