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ADGRL2_ENST00000370728 ,ADGRL2 ,O95490
  • Uniprot Accession= O95490
  • Ensembl Transcript= ENST00000370728.5
  • Uniprot Name= ADGRL2
  • Name= Adhesion G protein-coupled receptor L2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 17
  • Number of Interaction partner in biogrid: 0
  • Number of Interaction partner in hippie: 74
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 Census Yes 1 hippie 248 1247 180 180 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie 18 5 0 0 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BRD8 BRD8 Q9H0E9 Bromodomain-containing protein 8 chr5 Not Cancer Driver No 1 hippie 189 934 147 147 0
C11orf52 C11orf52 Q96A22 Uncharacterized protein C11orf52 chr11 Not Cancer Driver No 1 hippie 15 108 12 12 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie 30 2 0 0 0
CD9 CD9 P21926 CD9 antigen chr12 Not Cancer Driver No 1 intact, hippie 22 0 0 0 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 Not Cancer Driver No 1 hippie 58 69 10 10 9
CTDSPL CTDSPL O15194 CTD small phosphatase-like protein chr3 Not Cancer Driver No 1 intact, hippie 32 60 4 4 0
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 64 102 2 2 0
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie 51 98 19 19 0
DIRAS3_ENST00000646789 DIRAS3 O95661 GTP-binding protein Di-Ras3 chr1 Not Cancer Driver No 1 hippie 38 21 3 3 0
DNAJC16 DNAJC16 Q9Y2G8 DnaJ homolog subfamily C member 16 chr1 Not Cancer Driver No 1 hippie 84 63 2 2 0
DNAJC25 DNAJC25 Q9H1X3 DnaJ homolog subfamily C member 25 chr9 Not Cancer Driver No 1 hippie 37 39 3 3 0
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 Not Cancer Driver No 1 hippie 23 46 6 6 1
DNAJC5B DNAJC5B Q9UF47 DnaJ homolog subfamily C member 5B chr8 Not Cancer Driver No 1 hippie 64 31 7 7 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 Not Cancer Driver No 1 intact 182 140 24 24 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 Census, Compendium Yes 1 intact 280 71 15 15 0
FAM160A1_ENST00000505231 FHIP1A Q05DH4 FHF complex subunit HOOK interacting protein 1A chr4 Not Cancer Driver No 1 intact 47 341 8 8 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie 43 122 15 15 0
FLRT1 FLRT1 Q9NZU1 Leucine-rich repeat transmembrane protein FLRT1 chr11 Not Cancer Driver No 1 hippie 74 90 9 9 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX Not Cancer Driver No 1 intact, hippie 124 327 70 70 3
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie 86 110 26 26 50
GJD3 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie 5 79 0 0 0
HSPA12B HSPA12B Q96MM6 Heat shock 70 kDa protein 12B chr20 Not Cancer Driver No 1 hippie 75 126 18 18 0
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 Not Cancer Driver No 1 intact, hippie 36 204 21 21 1
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 Not Cancer Driver No 1 hippie 103 49 11 11 12
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 788 7 2 2 27
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie 47 93 10 10 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie 13 96 7 7 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 95 84 12 12 0
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie 14 328 14 14 0
MIB1 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 Not Cancer Driver No 1 hippie 122 282 34 34 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 1 intact, hippie 48 111 17 17 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
OTULINL OTULINL Q9NUU6 Inactive ubiquitin thioesterase OTULINL chr5 Not Cancer Driver No 1 hippie 59 21 0 0 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 1 hippie 200 1144 170 170 2
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PROM1 PROM1 O43490 Prominin-1 chr4 Not Cancer Driver No 1 hippie 94 76 9 9 3
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 Not Cancer Driver No 1 hippie 204 137 34 34 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie 22 58 4 4 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie 25 25 2 2 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 24 0 0 0 4
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie 52 19 2 2 0
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 20 10 0 0 0
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 18 10 0 0 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 41 12 3 3 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RHOQ RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 Not Cancer Driver No 1 hippie 25 0 0 0 0
RHOU RHOU Q7L0Q8 Rho-related GTP-binding protein RhoU chr1 Not Cancer Driver No 1 hippie 34 63 6 6 0
RND1 RND1 Q92730 Rho-related GTP-binding protein Rho6 chr12 Not Cancer Driver No 1 hippie 45 9 1 1 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 19 54 4 4 0
RND3_ENST00000263895 RND3 P61587 Rho-related GTP-binding protein RhoE chr2 Not Cancer Driver No 1 hippie 36 70 10 10 0
RPL31_ENST00000264258 RPL31 P62899 60S ribosomal protein L31 chr2 Not Cancer Driver No 1 hippie 19 69 14 14 0
RPS6KA2_ENST00000265678 RPS6KA2 Q15349 Ribosomal protein S6 kinase alpha-2 chr6 Not Cancer Driver No 1 hippie 133 91 15 15 0
SHANK1 SHANK1 Q9Y566 SH3 and multiple ankyrin repeat domains protein 1 chr19 Not Cancer Driver No 1 intact, hippie 288 1659 186 186 0
SHANK2_ENST00000601538 SHANK2 Q9UPX8 SH3 and multiple ankyrin repeat domains protein 2 chr11 Not Cancer Driver No 1 hippie 303 1379 262 262 0
SLC15A4 SLC15A4 Q8N697 Solute carrier family 15 member 4 chr12 Not Cancer Driver No 1 intact, hippie 66 23 4 4 0
SLC38A1_ENST00000546893 SLC38A1 Q9H2H9 Sodium-coupled neutral amino acid transporter 1 chr12 Not Cancer Driver No 1 intact, hippie 95 25 4 4 0
STX4 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie 50 152 20 20 0
STX6 STX6 O43752 Syntaxin-6 chr1 Not Cancer Driver No 1 hippie 33 78 11 11 0
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie 29 164 14 14 0
STYK1 STYK1 Q6J9G0 Tyrosine-protein kinase STYK1 chr12 Not Cancer Driver No 1 intact 83 35 10 10 0
TMEM17 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 intact, hippie 22 14 2 2 0
TMEM216 TMEM216 Q9P0N5 Transmembrane protein 216 chr11 Not Cancer Driver No 1 intact, hippie 11 0 0 0 7
TMPRSS11B TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie 95 5 0 0 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TRIM66_ENST00000299550 TRIM66 O15016 Tripartite motif-containing protein 66 chr11 Not Cancer Driver No 1 hippie 58 723 32 32 0
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 Not Cancer Driver No 1 intact 46 159 23 23 0
TSPAN5 TSPAN5 P62079 Tetraspanin-5 chr4 Not Cancer Driver No 1 intact, hippie 49 0 0 0 0
UNC93B1 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 Not Cancer Driver No 1 intact, hippie 57 127 5 5 0
ZFPL1 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie 40 127 16 16 0