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ADAM15 ,ADAM15 ,Q13444
  • Uniprot Accession= Q13444
  • Ensembl Transcript= ENST00000356955.6
  • Uniprot Name= ADAM15
  • Name= Disintegrin and metalloproteinase domain-containing protein 15
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 26
  • Number of Interaction partner in biogrid: 16
  • Number of Interaction partner in hippie: 73
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 139 604 73 73 2
ADAM33 ADAM33 Q9BZ11 Disintegrin and metalloproteinase domain-containing protein 33 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 94 165 28 28 0
ARHGEF6 ARHGEF6 Q15052 Rho guanine nucleotide exchange factor 6 chrX Not Cancer Driver No 1 intact, hippie 158 223 45 45 0
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 Not Cancer Driver No 1 hippie 106 301 39 39 0
ATXN1 ATXN1 P54253 Ataxin-1 chr6 Not Cancer Driver No 1 intact, hippie 193 604 168 168 0
BANP_ENST00000286122 BANP Q8N9N5 Protein BANP chr16 Not Cancer Driver No 1 hippie 74 311 43 43 0
BRICD5_ENST00000562360 BRICD5 Q6PL45 BRICHOS domain-containing protein 5 chr16 Not Cancer Driver No 1 hippie, biogrid 43 82 11 11 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX Census, Compendium Yes 1 hippie 147 114 27 27 110
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 intact, hippie 65 334 38 38 0
CLEC2B CLEC2B Q92478 C-type lectin domain family 2 member B chr12 Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 Not Cancer Driver No 1 hippie 66 259 44 44 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 151 8 1 1 0
ECEL1 ECEL1 O95672 Endothelin-converting enzyme-like 1 chr2 Not Cancer Driver No 1 hippie, biogrid 103 22 2 2 4
EDN3_ENST00000371028 EDN3 P14138 Endothelin-3 chr20 Not Cancer Driver No 1 hippie, biogrid 69 140 44 44 3
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FHL3 FHL3 Q13643 Four and a half LIM domains protein 3 chr1 Not Cancer Driver No 1 intact, hippie 33 0 0 0 0
FUT8_ENST00000394586 FUT8 Q9BYC5 Alpha-(1,6)-fucosyltransferase chr14 Not Cancer Driver No 1 hippie, biogrid 79 80 19 19 1
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 3 intact, hippie 28 10 1 1 0
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 Not Cancer Driver No 3 intact, hippie 112 124 25 25 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 hippie 183 265 37 37 6
ITGA5 ITGA5 P08648 Integrin alpha-5 chr12 Not Cancer Driver No 1 intact, hippie 127 201 29 29 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 Not Cancer Driver No 1 hippie 124 66 5 5 30
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 Census Yes 1 intact, hippie 139 43 10 10 1
ITSN1 ITSN1 Q15811 Intersectin-1 chr21 Not Cancer Driver No 1 hippie 214 797 107 107 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 86 94 13 13 1
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 95 84 12 12 0
LYPD4 LYPD4 Q6UWN0 Ly6/PLAUR domain-containing protein 4 chr19 Not Cancer Driver No 1 hippie, biogrid 44 0 0 0 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 Not Cancer Driver No 1 hippie 26 12 1 1 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 Not Cancer Driver No 2 intact, hippie 22 0 0 0 1
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 62 2 0 0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 38 49 5 5 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 Not Cancer Driver No 1 intact, hippie 37 181 12 12 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 1 intact, hippie 48 111 17 17 0
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX Census, Compendium Yes 1 hippie 101 349 64 64 0
NPHP1_ENST00000393272 NPHP1 O15259 Nephrocystin-1 chr2 Not Cancer Driver No 1 hippie 108 259 32 32 1
NUP62 NUP62 P37198 Nuclear pore glycoprotein p62 chr19 Not Cancer Driver No 1 intact, hippie 76 377 56 56 1
ODAM ODAM A1E959 Odontogenic ameloblast-associated protein chr4 Not Cancer Driver No 1 intact, hippie 51 140 18 18 0
OSTF1 OSTF1 Q92882 Osteoclast-stimulating factor 1 chr9 Not Cancer Driver No 1 intact, hippie 18 51 2 2 0
PACSIN3_ENST00000298838 PACSIN3 Q9UKS6 Protein kinase C and casein kinase substrate in neurons protein 3 chr11 Not Cancer Driver No 2 intact, hippie 52 290 31 31 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 intact, hippie 154 268 61 61 2
PLD3_ENST00000409735 PLD3 Q8IV08 5'-3' exonuclease PLD3 chr19 Not Cancer Driver No 1 biogrid 70 62 7 7 0
PRG2 PRG2 P13727 Bone marrow proteoglycan chr11 Not Cancer Driver No 1 hippie, biogrid 45 65 15 15 0
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 Census Yes 1 hippie 42 12 0 0 0
RBPMS_ENST00000320203 RBPMS Q93062 RNA-binding protein with multiple splicing chr8 Not Cancer Driver No 1 intact, hippie 23 87 11 11 0
SDF2L1 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 16 130 9 9 0
SFTPC SFTPC P11686 Pulmonary surfactant-associated protein C chr8 Not Cancer Driver No 1 hippie, biogrid 21 19 2 2 5
SH3D19_ENST00000409252 SH3D19 Q5HYK7 SH3 domain-containing protein 19 chr4 Not Cancer Driver No 1 hippie 86 526 52 52 0
SH3GL2 SH3GL2 Q99962 Endophilin-A1 chr9 Not Cancer Driver No 1 intact, hippie 76 214 50 50 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 Not Cancer Driver No 1 hippie 41 82 10 10 0
SH3PXD2A_ENST00000369774 SH3PXD2A Q5TCZ1 SH3 and PX domain-containing protein 2A chr10 Not Cancer Driver No 1 hippie 141 797 101 101 0
SH3RF1 SH3RF1 Q7Z6J0 E3 ubiquitin-protein ligase SH3RF1 chr4 Not Cancer Driver No 1 intact, hippie 109 586 72 72 0
SH3RF3 SH3RF3 Q8TEJ3 E3 ubiquitin-protein ligase SH3RF3 chr2 Not Cancer Driver No 1 hippie 98 564 53 53 0
SNX30 SNX30 Q5VWJ9 Sorting nexin-30 chr9 Not Cancer Driver No 1 hippie 36 98 4 4 0
SNX33 SNX33 Q8WV41 Sorting nexin-33 chr15 Not Cancer Driver No 3 intact, hippie 63 204 18 18 0
SNX9 SNX9 Q9Y5X1 Sorting nexin-9 chr6 Not Cancer Driver No 3 intact, hippie 71 231 23 23 0
SORBS1_ENST00000361941 SORBS1 Q9BX66 Sorbin and SH3 domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie 161 1111 133 133 0
SORBS2_ENST00000284776 SORBS2 O94875 Sorbin and SH3 domain-containing protein 2 chr4 Not Cancer Driver No 1 intact, hippie 172 854 137 137 0
SORBS3 SORBS3 O60504 Vinexin chr8 Not Cancer Driver No 1 hippie 62 577 56 56 0
SP4 SP4 Q02446 Transcription factor Sp4 chr7 Not Cancer Driver No 1 intact, hippie 95 532 71 71 0
SPAG5 SPAG5 Q96R06 Sperm-associated antigen 5 chr17 Not Cancer Driver No 1 intact, hippie 136 636 83 83 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
ST8SIA5_ENST00000315087 ST8SIA5 O15466 Alpha-2,8-sialyltransferase 8E chr18 Not Cancer Driver No 1 hippie, biogrid 98 0 0 0 0
TEC TEC P42680 Tyrosine-protein kinase Tec chr4 Census, Compendium Yes 1 hippie 91 57 15 15 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 31 56 4 4 1
TMPRSS11B TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie, biogrid 95 5 0 0 0
TMPRSS2_ENST00000458356 TMPRSS2 O15393 Transmembrane protease serine 2 chr21 Census Yes 1 hippie, biogrid 66 25 5 5 0
TMPRSS4_ENST00000437212 TMPRSS4 Q9NRS4 Transmembrane protease serine 4 chr11 Not Cancer Driver No 1 hippie, biogrid 47 35 4 4 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIP13 TRIP13 Q15645 Pachytene checkpoint protein 2 homolog chr5 Not Cancer Driver No 1 intact, hippie 62 30 6 6 1
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie 65 62 10 10 0