Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABI1 | ABI1 | Q8IZP0 | Abl interactor 1 | chr10 | Census, Compendium | Yes | 1 | hippie | 55 | 360 | 39 | 39 | 0 |
| ACTA2 | ACTA2 | P62736 | Actin, aortic smooth muscle | chr10 | Not Cancer Driver | No | 1 | hippie | 50 | 39 | 4 | 4 | 17 |
| ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 112 | 43 | 5 | 5 | 5 |
| ACTN1_ENST00000193403 | ACTN1 | P12814 | Alpha-actinin-1 | chr14 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 108 | 195 | 30 | 30 | 6 |
| ACTN2_ENST00000366578 | ACTN2 | P35609 | Alpha-actinin-2 | chr1 | Not Cancer Driver | No | 6 | intact, hippie | 227 | 131 | 29 | 29 | 9 |
| ACTN3_ENST00000513398 | ACTN3 | Q08043 | Alpha-actinin-3 | chr11 | Not Cancer Driver | No | 1 | hippie | 123 | 135 | 13 | 13 | 0 |
| ACTN4 | ACTN4 | O43707 | Alpha-actinin-4 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 131 | 244 | 42 | 42 | 8 |
| ADAM12 | ADAM12 | O43184 | Disintegrin and metalloproteinase domain-containing protein 12 | chr10 | Not Cancer Driver | No | 1 | hippie | 165 | 205 | 37 | 37 | 0 |
| ADORA2A | ADORA2A | P29274 | Adenosine receptor A2a | chr22 | Not Cancer Driver | No | 1 | hippie | 61 | 93 | 11 | 11 | 0 |
| AGRN | AGRN | O00468 | Agrin | chr1 | Not Cancer Driver | No | 1 | hippie | 188 | 490 | 40 | 40 | 5 |
| AKT2 | AKT2 | P31751 | RAC-beta serine/threonine-protein kinase | chr19 | Census | Yes | 1 | hippie | 77 | 84 | 9 | 9 | 2 |
| AKTIP_ENST00000570004 | AKTIP | Q9H8T0 | AKT-interacting protein | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 33 | 95 | 10 | 10 | 0 |
| ANG | ANG | P03950 | Angiogenin | chr14 | Not Cancer Driver | No | 1 | hippie | 19 | 36 | 2 | 2 | 14 |
| ANGPTL7 | ANGPTL7 | O43827 | Angiopoietin-related protein 7 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 38 | 33 | 7 | 7 | 0 |
| ANLN | ANLN | Q9NQW6 | Anillin | chr7 | Not Cancer Driver | No | 1 | hippie | 144 | 767 | 104 | 104 | 2 |
| APPL1 | APPL1 | Q9UKG1 | DCC-interacting protein 13-alpha | chr3 | Not Cancer Driver | No | 1 | hippie | 67 | 292 | 31 | 31 | 1 |
| ARX | ARX | Q96QS3 | Homeobox protein ARX | chrX | Not Cancer Driver | No | 1 | intact, hippie | 33 | 423 | 18 | 18 | 9 |
| ASH2L | ASH2L | Q9UBL3 | Set1/Ash2 histone methyltransferase complex subunit ASH2 | chr8 | Not Cancer Driver | No | 1 | hippie | 95 | 293 | 39 | 39 | 0 |
| ATP5MC1_ENST00000355938 | ATP5MC1 | P05496 | ATP synthase F(0) complex subunit C1, mitochondrial | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 14 | 0 | 0 | 0 | 0 |
| ATXN2_ENST00000550104 | ATXN2 | Q99700 | Ataxin-2 | chr12 | Not Cancer Driver | No | 1 | hippie | 146 | 1228 | 134 | 134 | 0 |
| ATXN7_ENST00000487717 | ATXN7 | O15265 | Ataxin-7 | chr3 | Not Cancer Driver | No | 1 | hippie | 95 | 797 | 82 | 82 | 0 |
| BAD_ENST00000309032 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | Not Cancer Driver | No | 1 | hippie | 14 | 163 | 14 | 14 | 0 |
| BRMS1L | BRMS1L | Q5PSV4 | Breast cancer metastasis-suppressor 1-like protein | chr14 | Not Cancer Driver | No | 1 | hippie | 35 | 160 | 17 | 17 | 0 |
| CACNA1C | CACNA1C | Q13936 | Voltage-dependent L-type calcium channel subunit alpha-1C | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 455 | 744 | 146 | 146 | 14 |
| CACNA1D_ENST00000350061 | CACNA1D | Q01668 | Voltage-dependent L-type calcium channel subunit alpha-1D | chr3 | Census, Compendium | Yes | 1 | hippie | 342 | 736 | 126 | 126 | 2 |
| CADPS | CADPS | Q9ULU8 | Calcium-dependent secretion activator 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 298 | 336 | 71 | 71 | 0 |
| CALM1 | CALM1 | P0DP23 | Calmodulin-1 | chr14 | Not Cancer Driver | No | 1 | hippie | 19 | 115 | 15 | 15 | 7 |
| CAMK2A_ENST00000348628 | CAMK2A | Q9UQM7 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | chr5 | Not Cancer Driver | No | 1 | hippie | 83 | 62 | 10 | 10 | 7 |
| CAMK2D_ENST00000342666 | CAMK2D | Q13557 | Calcium/calmodulin-dependent protein kinase type II subunit delta | chr4 | Not Cancer Driver | No | 1 | hippie | 57 | 84 | 10 | 10 | 0 |
| CAMK2G_ENST00000423381 | CAMK2G | Q13555 | Calcium/calmodulin-dependent protein kinase type II subunit gamma | chr10 | Not Cancer Driver | No | 1 | hippie | 68 | 145 | 14 | 14 | 1 |
| CAPN1_ENST00000533129 | CAPN1 | P07384 | Calpain-1 catalytic subunit | chr11 | Not Cancer Driver | No | 1 | hippie | 68 | 32 | 2 | 2 | 1 |
| CD27 | CD27 | P26842 | CD27 antigen | chr12 | Not Cancer Driver | No | 1 | hippie | 30 | 92 | 11 | 11 | 1 |
| CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 1 | hippie | 287 | 145 | 18 | 18 | 151 |
| CHMP4B | CHMP4B | Q9H444 | Charged multivesicular body protein 4b | chr20 | Not Cancer Driver | No | 1 | hippie | 25 | 201 | 22 | 22 | 2 |
| CHMP4C | CHMP4C | Q96CF2 | Charged multivesicular body protein 4c | chr8 | Not Cancer Driver | No | 1 | hippie | 33 | 224 | 31 | 31 | 0 |
| CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
| CLEC4D | CLEC4D | Q8WXI8 | C-type lectin domain family 4 member D | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 59 | 17 | 3 | 3 | 0 |
| CNNM3 | CNNM3 | Q8NE01 | Metal transporter CNNM3 | chr2 | Not Cancer Driver | No | 1 | hippie | 47 | 101 | 7 | 7 | 0 |
| COIL | COIL | P38432 | Coilin | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 61 | 385 | 42 | 42 | 0 |
| CRABP2_ENST00000368221 | CRABP2 | P29373 | Cellular retinoic acid-binding protein 2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 27 | 23 | 6 | 6 | 0 |
| CRADD_ENST00000332896 | CRADD | P78560 | Death domain-containing protein CRADD | chr12 | Not Cancer Driver | No | 1 | hippie | 35 | 45 | 5 | 5 | 1 |
| CSRP3 | CSRP3 | P50461 | Cysteine and glycine-rich protein 3 | chr11 | Not Cancer Driver | No | 1 | hippie | 25 | 31 | 1 | 1 | 2 |
| DDX58 | DDX58 | O95786 | Antiviral innate immune response receptor RIG-I | chr9 | Not Cancer Driver | No | 1 | hippie | 118 | 61 | 10 | 10 | 2 |
| DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 132 | 514 | 82 | 82 | 0 |
| DLG1_ENST00000419354 | DLG1 | Q12959 | Disks large homolog 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 120 | 460 | 67 | 67 | 0 |
| DLG4_ENST00000399506 | DLG4 | P78352 | Disks large homolog 4 | chr17 | Not Cancer Driver | No | 1 | hippie | 116 | 232 | 55 | 55 | 0 |
| DYSF_ENST00000258104 | DYSF | O75923 | Dysferlin | chr2 | Not Cancer Driver | No | 1 | hippie | 467 | 329 | 64 | 64 | 55 |
| ECT2 | ECT2 | Q9H8V3 | Protein ECT2 | chr3 | Not Cancer Driver | No | 1 | hippie | 104 | 284 | 33 | 33 | 0 |
| EPS8L1 | EPS8L1 | Q8TE68 | Epidermal growth factor receptor kinase substrate 8-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 116 | 521 | 96 | 96 | 0 |
| ERBIN_ENST00000284037 | ERBIN | Q96RT1 | Erbin | chr5 | Not Cancer Driver | No | 1 | hippie | 167 | 967 | 118 | 118 | 0 |
| EXOC1 | EXOC1 | Q9NV70 | Exocyst complex component 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 128 | 154 | 22 | 22 | 0 |
| FAM50B | FAM50B | Q9Y247 | Protein FAM50B | chr6 | Not Cancer Driver | No | 1 | hippie | 61 | 165 | 31 | 31 | 0 |
| FBXL22 | FBXL22 | Q6P050 | F-box and leucine-rich protein 22 | chr15 | Not Cancer Driver | No | 1 | hippie | 15 | 125 | 3 | 3 | 0 |
| FEZ1 | FEZ1 | Q99689 | Fasciculation and elongation protein zeta-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 66 | 277 | 49 | 49 | 0 |
| FXR1 | FXR1 | P51114 | Fragile X mental retardation syndrome-related protein 1 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 88 | 312 | 53 | 53 | 0 |
| GATA3_ENST00000346208 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | Census, Compendium | Yes | 1 | intact, hippie | 111 | 364 | 87 | 87 | 2 |
| GOLGA7_ENST00000518270 | GOLGA7 | Q7Z5G4 | Golgin subfamily A member 7 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 8 | 6 | 0 | 0 | 0 |
| GRIN1_ENST00000371561 | GRIN1 | Q05586 | Glutamate receptor ionotropic, NMDA 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 88 | 190 | 15 | 15 | 13 |
| GRIN2B | GRIN2B | Q13224 | Glutamate receptor ionotropic, NMDA 2B | chr12 | Not Cancer Driver | No | 1 | hippie | 413 | 426 | 147 | 147 | 11 |
| HIST1H4A | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 15 | 31 | 5 | 5 | 0 |
| HIST1H4B | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 29 | 31 | 6 | 6 | 0 |
| HIST1H4C | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 29 | 31 | 7 | 7 | 0 |
| HIST1H4D | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 32 | 31 | 8 | 8 | 0 |
| HIST1H4E | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 45 | 31 | 14 | 14 | 0 |
| HIST1H4F | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 30 | 31 | 7 | 7 | 0 |
| HIST1H4H | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 22 | 31 | 9 | 9 | 0 |
| HIST1H4I | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 33 | 31 | 10 | 10 | 0 |
| HIST1H4J | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 26 | 31 | 9 | 9 | 0 |
| HIST1H4K | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 44 | 31 | 13 | 13 | 0 |
| HIST1H4L | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 25 | 31 | 14 | 14 | 0 |
| HIST2H2BE | H2BC21 | Q16778 | Histone H2B type 2-E | chr1 | Not Cancer Driver | No | 1 | intact | 47 | 77 | 30 | 30 | 0 |
| HIST4H4 | H4-16 | P62805 | Histone H4 | chr12 | Not Cancer Driver | No | 1 | intact | 21 | 31 | 7 | 7 | 0 |
| HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 10 | 118 | 8 | 8 | 20 |
| HSPB8 | HSPB8 | Q9UJY1 | Heat shock protein beta-8 | chr12 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 40 | 130 | 31 | 31 | 5 |
| HTR1B | HTR1B | P28222 | 5-hydroxytryptamine receptor 1B | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 91 | 33 | 15 | 15 | 0 |
| HTT | HTT | P42858 | Huntingtin | chr4 | Not Cancer Driver | No | 1 | hippie | 336 | 666 | 69 | 69 | 2 |
| IGSF8_ENST00000614243 | IGSF8 | Q969P0 | Immunoglobulin superfamily member 8 | chr1 | Not Cancer Driver | No | 1 | hippie | 93 | 207 | 32 | 32 | 0 |
| ITGB3BP_ENST00000271002 | ITGB3BP | Q13352 | Centromere protein R | chr1 | Not Cancer Driver | No | 1 | hippie | 19 | 122 | 14 | 14 | 0 |
| KAT2B | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | Not Cancer Driver | No | 1 | hippie | 107 | 266 | 27 | 27 | 0 |
| KATNAL2_ENST00000356157 | KATNAL2 | Q8IYT4 | Katanin p60 ATPase-containing subunit A-like 2 | chr18 | Not Cancer Driver | No | 1 | hippie | 84 | 142 | 30 | 30 | 0 |
| KCNA4 | KCNA4 | P22459 | Potassium voltage-gated channel subfamily A member 4 | chr11 | Not Cancer Driver | No | 1 | hippie | 213 | 233 | 82 | 82 | 0 |
| KCNA5 | KCNA5 | P22460 | Potassium voltage-gated channel subfamily A member 5 | chr12 | Not Cancer Driver | No | 2 | intact, hippie | 213 | 218 | 53 | 53 | 0 |
| KCNN2 | KCNN2 | Q9H2S1 | Small conductance calcium-activated potassium channel protein 2 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 112 | 175 | 33 | 33 | 0 |
| KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 774 | 102 | 102 | 2 |
| KIF20A | KIF20A | O95235 | Kinesin-like protein KIF20A | chr5 | Not Cancer Driver | No | 1 | hippie | 79 | 340 | 40 | 40 | 1 |
| LDB3_ENST00000361373 | LDB3 | O75112 | LIM domain-binding protein 3 | chr10 | Not Cancer Driver | No | 1 | hippie | 107 | 529 | 71 | 71 | 4 |
| LRP12 | LRP12 | Q9Y561 | Low-density lipoprotein receptor-related protein 12 | chr8 | Not Cancer Driver | No | 1 | hippie | 199 | 240 | 54 | 54 | 0 |
| LRRC7 | LRRC7 | Q96NW7 | Leucine-rich repeat-containing protein 7 | chr1 | Not Cancer Driver | No | 1 | hippie | 474 | 1058 | 331 | 331 | 0 |
| MAST2 | MAST2 | Q6P0Q8 | Microtubule-associated serine/threonine-protein kinase 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 187 | 1326 | 133 | 133 | 0 |
| MED14 | MED14 | O60244 | Mediator of RNA polymerase II transcription subunit 14 | chrX | Not Cancer Driver | No | 1 | hippie | 182 | 318 | 45 | 45 | 0 |
| MICALL2 | MICALL2 | Q8IY33 | MICAL-like protein 2 | chr7 | Not Cancer Driver | No | 3 | intact, hippie | 110 | 675 | 88 | 88 | 0 |
| MOS | MOS | P00540 | Proto-oncogene serine/threonine-protein kinase mos | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 94 | 16 | 4 | 4 | 0 |
| MRPL10_ENST00000351111 | MRPL10 | Q7Z7H8 | 39S ribosomal protein L10, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie | 37 | 40 | 6 | 6 | 0 |
| MYBPC2 | MYBPC2 | Q14324 | Myosin-binding protein C, fast-type | chr19 | Not Cancer Driver | No | 1 | hippie | 198 | 261 | 43 | 43 | 0 |
| MYH1 | MYH1 | P12882 | Myosin-1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 546 | 1153 | 335 | 335 | 0 |
| MYH2_ENST00000397183 | MYH2 | Q9UKX2 | Myosin-2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 572 | 1073 | 338 | 338 | 1 |
| MYH3 | MYH3 | P11055 | Myosin-3 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 312 | 967 | 179 | 179 | 14 |
| MYH4 | MYH4 | Q9Y623 | Myosin-4 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 464 | 1138 | 288 | 288 | 0 |
| MYH6 | MYH6 | P13533 | Myosin-6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 392 | 1112 | 238 | 238 | 7 |
| MYH7 | MYH7 | P12883 | Myosin-7 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 464 | 1107 | 276 | 276 | 200 |
| MYH8 | MYH8 | P13535 | Myosin-8 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 498 | 1086 | 315 | 315 | 2 |
| MYOM2 | MYOM2 | P54296 | Myomesin-2 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 356 | 266 | 58 | 58 | 0 |
| MYOT | MYOT | Q9UBF9 | Myotilin | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 78 | 280 | 39 | 39 | 6 |
| MYOZ1 | MYOZ1 | Q9NP98 | Myozenin-1 | chr10 | Not Cancer Driver | No | 1 | hippie | 49 | 223 | 39 | 39 | 0 |
| MYOZ2 | MYOZ2 | Q9NPC6 | Myozenin-2 | chr4 | Not Cancer Driver | No | 1 | hippie | 50 | 197 | 38 | 38 | 2 |
| MYOZ3_ENST00000517768 | MYOZ3 | Q8TDC0 | Myozenin-3 | chr5 | Not Cancer Driver | No | 1 | hippie | 40 | 211 | 27 | 27 | 0 |
| MYPN_ENST00000540630 | MYPN | Q86TC9 | Myopalladin | chr10 | Not Cancer Driver | No | 1 | hippie | 262 | 925 | 182 | 182 | 17 |
| NCAPH2_ENST00000420993 | NCAPH2 | Q6IBW4 | Condensin-2 complex subunit H2 | chr22 | Not Cancer Driver | No | 1 | hippie | 67 | 335 | 39 | 39 | 0 |
| NCOA1_ENST00000348332 | NCOA1 | Q15788 | Nuclear receptor coactivator 1 | chr2 | Census, Compendium | Yes | 1 | hippie | 188 | 1217 | 149 | 149 | 0 |
| NCOA2 | NCOA2 | Q15596 | Nuclear receptor coactivator 2 | chr8 | Census, Compendium | Yes | 1 | hippie | 210 | 1281 | 185 | 185 | 0 |
| NCOR1 | NCOR1 | O75376 | Nuclear receptor corepressor 1 | chr17 | Census, Compendium | Yes | 1 | hippie | 352 | 2347 | 340 | 340 | 0 |
| NKAPD1_ENST00000420986 | NKAPD1 | Q6ZUT1 | Uncharacterized protein NKAPD1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 35 | 261 | 31 | 31 | 0 |
| NOS3 | NOS3 | P29474 | Nitric oxide synthase, endothelial | chr7 | Not Cancer Driver | No | 1 | hippie | 168 | 347 | 38 | 38 | 0 |
| NR1I2_ENST00000393716 | NR1I2 | O75469 | Nuclear receptor subfamily 1 group I member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 60 | 81 | 8 | 8 | 0 |
| NRAP_ENST00000359988 | NRAP | Q86VF7 | Nebulin-related-anchoring protein | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 302 | 706 | 139 | 139 | 0 |
| NRIP1_ENST00000400199 | NRIP1 | P48552 | Nuclear receptor-interacting protein 1 | chr21 | Not Cancer Driver | No | 1 | hippie | 141 | 998 | 124 | 124 | 0 |
| ODF3B | ODF3B | A8MYP8 | Outer dense fiber protein 3B | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 10 | 183 | 5 | 5 | 0 |
| PALLD_ENST00000512127 | PALLD | Q8WX93-8 | Isoform 8 of Palladin | chr4 | Not Cancer Driver | No | 1 | hippie | 105 | 509 | 65 | 65 | 0 |
| PDLIM1 | PDLIM1 | O00151 | PDZ and LIM domain protein 1 | chr10 | Not Cancer Driver | No | 4 | hippie, biogrid | 62 | 219 | 39 | 39 | 0 |
| PDLIM3 | PDLIM3 | Q53GG5 | PDZ and LIM domain protein 3 | chr4 | Not Cancer Driver | No | 2 | intact, hippie | 44 | 235 | 35 | 35 | 0 |
| PDLIM7 | PDLIM7 | Q9NR12 | PDZ and LIM domain protein 7 | chr5 | Not Cancer Driver | No | 1 | hippie | 48 | 244 | 20 | 20 | 0 |
| PKD2 | PKD2 | Q13563 | Polycystin-2 | chr4 | Not Cancer Driver | No | 1 | hippie | 113 | 375 | 35 | 35 | 10 |
| PKN1_ENST00000242783 | PKN1 | Q16512 | Serine/threonine-protein kinase N1 | chr19 | Not Cancer Driver | No | 1 | hippie | 120 | 459 | 54 | 54 | 0 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PPP1CB_ENST00000358506 | PPP1CB | P62140 | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 47 | 25 | 5 | 5 | 5 |
| PPP1R9B | PPP1R9B | Q96SB3 | Neurabin-2 | chr17 | Not Cancer Driver | No | 1 | hippie | 47 | 695 | 35 | 35 | 0 |
| PRC1 | PRC1 | O43663 | Protein regulator of cytokinesis 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 63 | 235 | 26 | 26 | 0 |
| PSMA1_ENST00000396394 | PSMA1 | P25786 | Proteasome subunit alpha type-1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 48 | 51 | 9 | 9 | 0 |
| PSMA3 | PSMA3 | P25788 | Proteasome subunit alpha type-3 | chr14 | Not Cancer Driver | No | 1 | hippie | 27 | 30 | 5 | 5 | 0 |
| PSMB5 | PSMB5 | P28074 | Proteasome subunit beta type-5 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 9 | 0 | 0 | 0 |
| QARS | QARS1 | P47897 | Glutamine--tRNA ligase | chr3 | Not Cancer Driver | No | 1 | intact | 101 | 106 | 16 | 16 | 4 |
| RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 34 | 13 | 0 | 0 | 0 |
| RAVER1_ENST00000615032 | RAVER1 | Q8IY67 | Ribonucleoprotein PTB-binding 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 61 | 330 | 22 | 22 | 0 |
| RGS9 | RGS9 | O75916 | Regulator of G-protein signaling 9 | chr17 | Not Cancer Driver | No | 1 | hippie | 138 | 240 | 65 | 65 | 1 |
| RPL35 | RPL35 | P42766 | 60S ribosomal protein L35 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 12 | 65 | 9 | 9 | 0 |
| RPP14_ENST00000295959 | RPP14 | O95059 | Ribonuclease P protein subunit p14 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 8 | 0 | 0 | 0 | 0 |
| RTP5 | RTP5 | Q14D33 | Receptor-transporting protein 5 | chr2 | Not Cancer Driver | No | 1 | hippie | 92 | 148 | 34 | 34 | 0 |
| SAXO1 | SAXO1 | Q8IYX7 | Stabilizer of axonemal microtubules 1 | chr9 | Not Cancer Driver | No | 3 | intact, hippie | 63 | 249 | 35 | 35 | 0 |
| SCRIB_ENST00000320476 | SCRIB | Q14160 | Protein scribble homolog | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 196 | 1064 | 135 | 135 | 2 |
| SELE | SELE | P16581 | E-selectin | chr1 | Not Cancer Driver | No | 1 | hippie | 137 | 12 | 0 | 0 | 0 |
| SMARCA2 | SMARCA2 | P51531 | Probable global transcription activator SNF2L2 | chr9 | Not Cancer Driver | No | 1 | hippie | 273 | 1009 | 160 | 160 | 42 |
| SNAI1 | SNAI1 | O95863 | Zinc finger protein SNAI1 | chr20 | Not Cancer Driver | No | 1 | hippie | 52 | 97 | 11 | 11 | 0 |
| SNAPIN | SNAPIN | O95295 | SNARE-associated protein Snapin | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 9 | 62 | 5 | 5 | 0 |
| SNW1_ENST00000261531 | SNW1 | Q13573 | SNW domain-containing protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 62 | 488 | 56 | 56 | 0 |
| SP100_ENST00000264052 | SP100 | P23497 | Nuclear autoantigen Sp-100 | chr2 | Not Cancer Driver | No | 1 | hippie | 136 | 680 | 101 | 101 | 0 |
| SPA17 | SPA17 | Q15506 | Sperm surface protein Sp17 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 18 | 137 | 15 | 15 | 0 |
| SRP9 | SRP9 | P49458 | Signal recognition particle 9 kDa protein | chr1 | Not Cancer Driver | No | 1 | intact | 14 | 4 | 1 | 1 | 0 |
| SSSCA1 | ZNRD2 | O60232 | Protein ZNRD2 | chr11 | Not Cancer Driver | No | 1 | intact | 19 | 103 | 12 | 12 | 0 |
| SSX2IP | SSX2IP | Q9Y2D8 | Afadin- and alpha-actinin-binding protein | chr1 | Not Cancer Driver | No | 1 | hippie | 82 | 265 | 31 | 31 | 0 |
| ST7 | ST7 | Q9NRC1 | Suppressor of tumorigenicity 7 protein | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 62 | 64 | 5 | 5 | 0 |
| SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 10 | 76 | 7 | 7 | 0 |
| SUMO3_ENST00000332859 | SUMO3 | P55854 | Small ubiquitin-related modifier 3 | chr21 | Not Cancer Driver | No | 1 | hippie | 7 | 87 | 5 | 5 | 0 |
| SYNPO2L | SYNPO2L | Q9H987 | Synaptopodin 2-like protein | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 103 | 950 | 99 | 99 | 0 |
| SYNPO2_ENST00000429713 | SYNPO2 | Q9UMS6 | Synaptopodin-2 | chr4 | Not Cancer Driver | No | 1 | hippie | 240 | 978 | 219 | 219 | 0 |
| TCTEX1D2 | DYNLT2B | Q8WW35 | Dynein light chain Tctex-type protein 2B | chr3 | Not Cancer Driver | No | 1 | intact | 22 | 30 | 10 | 10 | 0 |
| TNN | TNN | Q9UQP3 | Tenascin-N | chr1 | Not Cancer Driver | No | 1 | hippie | 426 | 637 | 231 | 231 | 0 |
| TNNI1_ENST00000336092 | TNNI1 | P19237 | Troponin I, slow skeletal muscle | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 72 | 8 | 8 | 0 |
| TOLLIP | TOLLIP | Q9H0E2 | Toll-interacting protein | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 38 | 81 | 12 | 12 | 0 |
| TPM1_ENST00000403994 | TPM1 | P09493 | Tropomyosin alpha-1 chain | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 234 | 29 | 29 | 8 |
| TPM2 | TPM2 | P07951 | Tropomyosin beta chain | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 232 | 35 | 35 | 15 |
| TPM3 | TPM3 | P06753 | Tropomyosin alpha-3 chain | chr1 | Census | Yes | 1 | hippie, biogrid | 35 | 230 | 27 | 27 | 21 |
| TPM4_ENST00000300933 | TPM4 | P67936 | Tropomyosin alpha-4 chain | chr19 | Census | Yes | 1 | hippie, biogrid | 28 | 216 | 28 | 28 | 0 |
| TSC1 | TSC1 | Q92574 | Hamartin | chr9 | Census, Compendium | Yes | 1 | intact, hippie | 135 | 732 | 78 | 78 | 11 |
| TSC2 | TSC2 | P49815 | Tuberin | chr16 | Census, Compendium | Yes | 1 | intact, hippie | 192 | 563 | 50 | 50 | 53 |
| TTN_ENST00000615779 | TTN | Q8WZ42 | Titin | chr2 | Not Cancer Driver | No | 5 | intact, hippie | 7917 | 12926 | 2861 | 2861 | 10 |
| TUBA1A | TUBA1A | Q71U36 | Tubulin alpha-1A chain | chr12 | Not Cancer Driver | No | 1 | hippie | 59 | 52 | 11 | 11 | 8 |
| TUBA4A | TUBA4A | P68366 | Tubulin alpha-4A chain | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 73 | 39 | 4 | 4 | 5 |
| TULP3_ENST00000448120 | TULP3 | O75386 | Tubby-related protein 3 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 66 | 218 | 29 | 29 | 0 |
| USP2 | USP2 | O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 88 | 213 | 39 | 39 | 0 |
| UTRN | UTRN | P46939 | Utrophin | chr6 | Not Cancer Driver | No | 1 | hippie | 476 | 1283 | 183 | 183 | 0 |
| WDYHV1 | NTAQ1 | Q96HA8 | Protein N-terminal glutamine amidohydrolase | chr8 | Not Cancer Driver | No | 1 | intact | 38 | 26 | 3 | 3 | 0 |
| YWHAQ | YWHAQ | P27348 | 14-3-3 protein theta | chr2 | Not Cancer Driver | No | 1 | hippie | 29 | 41 | 6 | 6 | 0 |
| YWHAZ_ENST00000395956 | YWHAZ | P63104 | 14-3-3 protein zeta/delta | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 81 | 10 | 10 | 0 |
| ZC2HC1C | ZC2HC1C | Q53FD0 | Zinc finger C2HC domain-containing protein 1C | chr14 | Not Cancer Driver | No | 2 | intact, hippie | 39 | 395 | 32 | 32 | 0 |
| ZNF446 | ZNF446 | Q9NWS9 | Zinc finger protein 446 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 345 | 41 | 41 | 0 |
| ZYX | ZYX | Q15942 | Zyxin | chr7 | Not Cancer Driver | No | 1 | hippie | 83 | 385 | 52 | 52 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|