Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AAR2_ENST00000320849 | AAR2 | Q9Y312 | Protein AAR2 homolog | chr20 | Not Cancer Driver | No | 1 | hippie | 56 | 28 | 6 | 6 | 0 |
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | Census, Compendium | Yes | 1 | hippie | 139 | 604 | 73 | 73 | 2 |
| ABLIM2_ENST00000341937 | ABLIM2 | Q6H8Q1 | Actin-binding LIM protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 101 | 272 | 43 | 43 | 0 |
| ABLIM3_ENST00000309868 | ABLIM3 | O94929 | Actin-binding LIM protein 3 | chr5 | Not Cancer Driver | No | 1 | hippie | 125 | 282 | 62 | 62 | 0 |
| ABRA | ABRA | Q8N0Z2 | Actin-binding Rho-activating protein | chr8 | Not Cancer Driver | No | 1 | hippie | 108 | 285 | 86 | 86 | 0 |
| ABTB2 | ABTB2 | Q8N961 | Ankyrin repeat and BTB/POZ domain-containing protein 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 215 | 20 | 20 | 0 |
| ACTA1 | ACTA1 | P68133 | Actin, alpha skeletal muscle | chr1 | Not Cancer Driver | No | 21 | intact, hippie | 70 | 48 | 14 | 14 | 84 |
| ACTA2 | ACTA2 | P62736 | Actin, aortic smooth muscle | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 39 | 4 | 4 | 17 |
| ACTBL2 | ACTBL2 | Q562R1 | Beta-actin-like protein 2 | chr5 | Not Cancer Driver | No | 1 | hippie | 73 | 29 | 5 | 5 | 0 |
| ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | Not Cancer Driver | No | 1 | intact | 112 | 43 | 5 | 5 | 5 |
| ACTC1 | ACTC1 | P68032 | Actin, alpha cardiac muscle 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 114 | 48 | 19 | 19 | 11 |
| ACTG1_ENST00000575087 | ACTG1 | P63261 | Actin, cytoplasmic 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 73 | 42 | 10 | 10 | 16 |
| ACTN4 | ACTN4 | O43707 | Alpha-actinin-4 | chr19 | Not Cancer Driver | No | 1 | hippie | 131 | 244 | 42 | 42 | 8 |
| ACTR10 | ACTR10 | Q9NZ32 | Actin-related protein 10 | chr14 | Not Cancer Driver | No | 1 | hippie | 45 | 29 | 3 | 3 | 0 |
| ACTR1B | ACTR1B | P42025 | Beta-centractin | chr2 | Not Cancer Driver | No | 1 | hippie | 59 | 17 | 4 | 4 | 0 |
| ACTR2_ENST00000260641 | ACTR2 | P61160 | Actin-related protein 2 | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 51 | 6 | 2 | 2 | 0 |
| ACTR3 | ACTR3 | P61158 | Actin-related protein 3 | chr2 | Not Cancer Driver | No | 1 | intact | 32 | 16 | 2 | 2 | 0 |
| ADAM19_ENST00000517905 | ADAM19 | Q9H013 | Disintegrin and metalloproteinase domain-containing protein 19 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 172 | 370 | 77 | 77 | 0 |
| AFAP1_ENST00000358461 | AFAP1 | Q8N556 | Actin filament-associated protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 104 | 487 | 60 | 60 | 0 |
| AGRN | AGRN | O00468 | Agrin | chr1 | Not Cancer Driver | No | 1 | hippie | 188 | 490 | 40 | 40 | 5 |
| AIF1 | AIF1 | P55008 | Allograft inflammatory factor 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 14 | 61 | 6 | 6 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | Census, Compendium | Yes | 1 | hippie | 108 | 158 | 24 | 24 | 4 |
| AMOT | AMOT | Q4VCS5 | Angiomotin | chrX | Not Cancer Driver | No | 1 | hippie | 161 | 909 | 128 | 128 | 0 |
| ANGPTL8_ENST00000252453 | ANGPTL8 | Q6UXH0 | Angiopoietin-like protein 8 | chr19 | Not Cancer Driver | No | 1 | hippie | 17 | 26 | 6 | 6 | 0 |
| ANXA1_ENST00000257497 | ANXA1 | P04083 | Annexin A1 | chr9 | Not Cancer Driver | No | 1 | hippie | 59 | 61 | 12 | 12 | 0 |
| ANXA2_ENST00000396024 | ANXA2 | P07355 | Annexin A2 | chr15 | Not Cancer Driver | No | 1 | hippie | 49 | 20 | 4 | 4 | 0 |
| ANXA8L1 | ANXA8L1 | Q5VT79 | Annexin A8-like protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 5 | 37 | 0 | 0 | 0 |
| APC2_ENST00000233607 | APC2 | O95996 | Adenomatous polyposis coli protein 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 117 | 1725 | 78 | 78 | 0 |
| ARPC1B_ENST00000431816 | ARPC1B | O15143 | Actin-related protein 2/3 complex subunit 1B | chr7 | Not Cancer Driver | No | 1 | intact | 37 | 34 | 1 | 1 | 0 |
| ARPC2_ENST00000315717 | ARPC2 | O15144 | Actin-related protein 2/3 complex subunit 2 | chr2 | Not Cancer Driver | No | 1 | intact | 40 | 49 | 8 | 8 | 0 |
| ARPC3 | ARPC3 | O15145 | Actin-related protein 2/3 complex subunit 3 | chr12 | Not Cancer Driver | No | 1 | intact | 17 | 26 | 6 | 6 | 0 |
| ARPC4_ENST00000397261 | ARPC4 | P59998 | Actin-related protein 2/3 complex subunit 4 | chr3 | Not Cancer Driver | No | 1 | intact | 11 | 3 | 0 | 0 | 0 |
| ARPC5_ENST00000359856 | ARPC5 | O15511 | Actin-related protein 2/3 complex subunit 5 | chr1 | Not Cancer Driver | No | 1 | intact | 15 | 66 | 7 | 7 | 0 |
| ARRB1 | ARRB1 | P49407 | Beta-arrestin-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 49 | 154 | 13 | 13 | 0 |
| ASCL4 | ASCL4 | Q6XD76 | Achaete-scute homolog 4 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 25 | 78 | 15 | 15 | 0 |
| BAIAP2 | BAIAP2 | Q9UQB8 | Brain-specific angiogenesis inhibitor 1-associated protein 2 | chr17 | Not Cancer Driver | No | 1 | intact | 85 | 330 | 52 | 52 | 0 |
| BIN1 | BIN1 | O00499 | Myc box-dependent-interacting protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 65 | 456 | 42 | 42 | 5 |
| BRD7_ENST00000394688 | BRD7 | Q9NPI1 | Bromodomain-containing protein 7 | chr16 | Compendium | Yes | 1 | hippie | 82 | 482 | 57 | 57 | 0 |
| BRK1 | BRK1 | Q8WUW1 | Protein BRICK1 | chr3 | Not Cancer Driver | No | 1 | hippie | 7 | 14 | 1 | 1 | 0 |
| BTF3 | BTF3 | P20290 | Transcription factor BTF3 | chr5 | Not Cancer Driver | No | 1 | hippie | 27 | 192 | 24 | 24 | 0 |
| BTK_ENST00000308731 | BTK | Q06187 | Tyrosine-protein kinase BTK | chrX | Census, Compendium | Yes | 1 | hippie | 147 | 114 | 27 | 27 | 110 |
| C17orf97 | C17orf97 | Q6ZQX7-4 | Isoform 4 of Protein LIAT1 | chr17 | Not Cancer Driver | No | 1 | hippie | 63 | 401 | 55 | 55 | 0 |
| CADM4 | CADM4 | Q8NFZ8 | Cell adhesion molecule 4 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 94 | 9 | 9 | 0 |
| CAMK2A_ENST00000348628 | CAMK2A | Q9UQM7 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 83 | 62 | 10 | 10 | 7 |
| CAP1_ENST00000372805 | CAP1 | Q01518 | Adenylyl cyclase-associated protein 1 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 70 | 156 | 31 | 31 | 0 |
| CAP2 | CAP2 | P40123 | Adenylyl cyclase-associated protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 171 | 28 | 28 | 0 |
| CAPG_ENST00000409724 | CAPG | P40121 | Macrophage-capping protein | chr2 | Not Cancer Driver | No | 1 | intact | 45 | 95 | 7 | 7 | 0 |
| CAPZA2 | CAPZA2 | P47755 | F-actin-capping protein subunit alpha-2 | chr7 | Not Cancer Driver | No | 1 | hippie | 37 | 19 | 0 | 0 | 0 |
| CBL | CBL | P22681 | E3 ubiquitin-protein ligase CBL | chr11 | Census, Compendium | Yes | 1 | hippie | 115 | 512 | 56 | 56 | 4 |
| CCDC69 | CCDC69 | A6NI79 | Coiled-coil domain-containing protein 69 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 162 | 20 | 20 | 0 |
| CCIN | CCIN | Q13939 | Calicin | chr9 | Not Cancer Driver | No | 1 | hippie | 100 | 2 | 1 | 1 | 0 |
| CCT2 | CCT2 | P78371 | T-complex protein 1 subunit beta | chr12 | Not Cancer Driver | No | 1 | hippie | 63 | 46 | 3 | 3 | 0 |
| CCT3 | CCT3 | P49368 | T-complex protein 1 subunit gamma | chr1 | Not Cancer Driver | No | 1 | intact | 71 | 95 | 12 | 12 | 0 |
| CCT4 | CCT4 | P50991 | T-complex protein 1 subunit delta | chr2 | Not Cancer Driver | No | 1 | hippie | 51 | 92 | 2 | 2 | 0 |
| CCT5 | CCT5 | P48643 | T-complex protein 1 subunit epsilon | chr5 | Not Cancer Driver | No | 2 | intact, hippie | 83 | 72 | 10 | 10 | 1 |
| CCT7 | CCT7 | Q99832 | T-complex protein 1 subunit eta | chr2 | Not Cancer Driver | No | 1 | intact | 59 | 36 | 6 | 6 | 0 |
| CCT8 | CCT8 | P50990 | T-complex protein 1 subunit theta | chr21 | Not Cancer Driver | No | 1 | intact | 41 | 36 | 2 | 2 | 0 |
| CD247 | CD247 | P20963 | T-cell surface glycoprotein CD3 zeta chain | chr1 | Not Cancer Driver | No | 1 | hippie | 33 | 91 | 24 | 24 | 0 |
| CDCA5 | CDCA5 | Q96FF9 | Sororin | chr11 | Not Cancer Driver | No | 1 | hippie | 32 | 211 | 26 | 26 | 0 |
| CDH2 | CDH2 | P19022 | Cadherin-2 | chr18 | Not Cancer Driver | No | 1 | hippie | 238 | 461 | 130 | 130 | 7 |
| CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 0 |
| CDKN2A_ENST00000304494 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | Census, Compendium | Yes | 1 | hippie | 166 | 83 | 88 | 88 | 36 |
| CEP55 | CEP55 | Q53EZ4 | Centrosomal protein of 55 kDa | chr10 | Not Cancer Driver | No | 1 | hippie | 59 | 264 | 26 | 26 | 0 |
| CEP57 | CEP57 | Q86XR8 | Centrosomal protein of 57 kDa | chr11 | Not Cancer Driver | No | 1 | hippie | 61 | 403 | 50 | 50 | 0 |
| CFL1_ENST00000308162 | CFL1 | P23528 | Cofilin-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 21 | 4 | 0 | 0 | 0 |
| CHMP1B | CHMP1B | Q7LBR1 | Charged multivesicular body protein 1b | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 133 | 16 | 16 | 0 |
| CHRDL2_ENST00000376332 | CHRDL2 | Q6WN34 | Chordin-like protein 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 104 | 20 | 20 | 0 |
| CLDN20 | CLDN20 | P56880 | Claudin-20 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 19 | 3 | 3 | 0 |
| CLIC5 | CLIC5 | Q9NZA1 | Chloride intracellular channel protein 5 | chr6 | Not Cancer Driver | No | 1 | hippie | 50 | 205 | 22 | 22 | 0 |
| CNN1 | CNN1 | P51911 | Calponin-1 | chr19 | Not Cancer Driver | No | 2 | intact, hippie | 56 | 200 | 39 | 39 | 0 |
| COASY_ENST00000421097 | COASY | Q13057 | Bifunctional coenzyme A synthase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 50 | 4 | 4 | 1 |
| CORO2B | CORO2B | Q9UQ03 | Coronin-2B | chr15 | Not Cancer Driver | No | 1 | hippie | 85 | 37 | 7 | 7 | 0 |
| COTL1 | COTL1 | Q14019 | Coactosin-like protein | chr16 | Not Cancer Driver | No | 1 | hippie | 17 | 7 | 2 | 2 | 0 |
| CSNK1A1_ENST00000377843 | CSNK1A1 | P48729 | Casein kinase I isoform alpha | chr5 | Not Cancer Driver | No | 1 | hippie | 44 | 46 | 3 | 3 | 0 |
| CTNNBL1 | CTNNBL1 | Q8WYA6 | Beta-catenin-like protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 72 | 158 | 24 | 24 | 0 |
| CTNND1 | CTNND1 | O60716 | Catenin delta-1 | chr11 | Census | Yes | 1 | hippie | 154 | 570 | 83 | 83 | 0 |
| CTTN_ENST00000301843 | CTTN | Q14247 | Src substrate cortactin | chr11 | Not Cancer Driver | No | 1 | hippie | 78 | 465 | 56 | 56 | 0 |
| CUL1_ENST00000602748 | CUL1 | Q13616 | Cullin-1 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 151 | 65 | 9 | 9 | 0 |
| CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | Not Cancer Driver | No | 1 | hippie | 188 | 372 | 41 | 41 | 3 |
| CYFIP1_ENST00000610365 | CYFIP1 | Q7L576 | Cytoplasmic FMR1-interacting protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 46 | 96 | 0 | 0 | 0 |
| CYTH1_ENST00000446868 | CYTH1 | Q15438 | Cytohesin-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 93 | 15 | 15 | 0 |
| DCPS | DCPS | Q96C86 | m7GpppX diphosphatase | chr11 | Not Cancer Driver | No | 1 | hippie | 48 | 53 | 6 | 6 | 1 |
| DHX9 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | Compendium | Yes | 1 | hippie | 182 | 331 | 42 | 42 | 0 |
| DLG1_ENST00000419354 | DLG1 | Q12959 | Disks large homolog 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 120 | 460 | 67 | 67 | 0 |
| DMAP1_ENST00000315913 | DMAP1 | Q9NPF5 | DNA methyltransferase 1-associated protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 49 | 269 | 28 | 28 | 0 |
| DMC1 | DMC1 | Q14565 | Meiotic recombination protein DMC1/LIM15 homolog | chr22 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 39 | 49 | 5 | 5 | 0 |
| DMD | DMD | P11532 | Dystrophin | chrX | Not Cancer Driver | No | 1 | hippie | 895 | 1399 | 329 | 329 | 14 |
| DNASE1_ENST00000246949 | DNASE1 | P24855 | Deoxyribonuclease-1 | chr16 | Not Cancer Driver | No | 5 | intact, hippie | 24 | 0 | 0 | 0 | 0 |
| DNM2_ENST00000355667 | DNM2 | P50570 | Dynamin-2 | chr19 | Census | Yes | 1 | hippie, biogrid | 138 | 270 | 43 | 43 | 22 |
| DNMBP | DNMBP | Q6XZF7 | Dynamin-binding protein | chr10 | Not Cancer Driver | No | 1 | hippie | 208 | 758 | 92 | 92 | 0 |
| DSTN | DSTN | P60981 | Destrin | chr20 | Not Cancer Driver | No | 1 | hippie | 18 | 0 | 0 | 0 | 0 |
| DTNA_ENST00000444659 | DTNA | Q9Y4J8 | Dystrobrevin alpha | chr18 | Not Cancer Driver | No | 1 | hippie | 162 | 412 | 86 | 86 | 0 |
| DUSP19 | DUSP19 | Q8WTR2 | Dual specificity protein phosphatase 19 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 34 | 15 | 5 | 5 | 0 |
| EBP | EBP | Q15125 | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 9 | 0 | 0 | 9 |
| EEF1A1 | EEF1A1 | P68104 | Elongation factor 1-alpha 1 | chr6 | Not Cancer Driver | No | 1 | intact | 109 | 100 | 14 | 14 | 0 |
| EFTUD2 | EFTUD2 | Q15029 | 116 kDa U5 small nuclear ribonucleoprotein component | chr17 | Compendium | Yes | 1 | hippie | 132 | 179 | 30 | 30 | 3 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
| ELOVL3 | ELOVL3 | Q9HB03 | Elongation of very long chain fatty acids protein 3 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 1 | 1 | 1 | 0 |
| EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 334 | 1790 | 196 | 196 | 1 |
| EPB41L2_ENST00000368128 | EPB41L2 | O43491 | Band 4.1-like protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 157 | 708 | 113 | 113 | 0 |
| EPB41_ENST00000373798 | EPB41 | P11171 | Protein 4.1 | chr1 | Not Cancer Driver | No | 1 | hippie | 101 | 557 | 69 | 69 | 0 |
| EPS8_ENST00000645775 | EPS8 | Q12929 | Epidermal growth factor receptor kinase substrate 8 | chr12 | Not Cancer Driver | No | 1 | hippie | 106 | 459 | 54 | 54 | 0 |
| ERBB3 | ERBB3 | P21860 | Receptor tyrosine-protein kinase erbB-3 | chr12 | Census, Compendium | Yes | 1 | hippie | 298 | 396 | 70 | 70 | 3 |
| ERRFI1 | ERRFI1 | Q9UJM3 | ERBB receptor feedback inhibitor 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 55 | 297 | 37 | 37 | 0 |
| ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
| ETV6 | ETV6 | P41212 | Transcription factor ETV6 | chr12 | Census, Compendium | Yes | 1 | hippie | 98 | 251 | 46 | 46 | 3 |
| FGD4_ENST00000427716 | FGD4 | Q96M96 | FYVE, RhoGEF and PH domain-containing protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie | 78 | 290 | 28 | 28 | 2 |
| FGD5 | FGD5 | Q6ZNL6 | FYVE, RhoGEF and PH domain-containing protein 5 | chr3 | Compendium | Yes | 1 | hippie, biogrid | 275 | 915 | 180 | 180 | 0 |
| FGFR1_ENST00000447712 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | Census, Compendium | Yes | 1 | hippie | 152 | 230 | 43 | 43 | 74 |
| FHOD1 | FHOD1 | Q9Y613 | FH1/FH2 domain-containing protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 151 | 575 | 82 | 82 | 0 |
| FKBP6 | FKBP6 | O75344 | Inactive peptidyl-prolyl cis-trans isomerase FKBP6 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 17 | 1 | 1 | 0 |
| FLNA | FLNA | P21333 | Filamin-A | chrX | Census | Yes | 1 | intact | 416 | 1456 | 214 | 214 | 28 |
| FOXRED2 | FOXRED2 | Q8IWF2 | FAD-dependent oxidoreductase domain-containing protein 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 97 | 48 | 5 | 5 | 0 |
| FSCN1 | FSCN1 | Q16658 | Fascin | chr7 | Not Cancer Driver | No | 1 | hippie | 58 | 81 | 5 | 5 | 0 |
| GAS2 | GAS2 | O43903 | Growth arrest-specific protein 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 73 | 92 | 16 | 16 | 0 |
| GAS7 | GAS7 | O60861 | Growth arrest-specific protein 7 | chr17 | Census | Yes | 1 | hippie | 78 | 318 | 57 | 57 | 0 |
| GBF1 | GBF1 | Q92538 | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 216 | 669 | 76 | 76 | 0 |
| GC_ENST00000273951 | GC | P02774 | Vitamin D-binding protein | chr4 | Not Cancer Driver | No | 1 | hippie | 93 | 13 | 3 | 3 | 0 |
| GJA1 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | Not Cancer Driver | No | 1 | hippie | 86 | 110 | 26 | 26 | 50 |
| GRB2_ENST00000392564 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 28 | 10 | 1 | 1 | 0 |
| GSN | GSN | P06396 | Gelsolin | chr9 | Not Cancer Driver | No | 2 | intact, hippie | 76 | 316 | 28 | 28 | 2 |
| HCLS1 | HCLS1 | P14317 | Hematopoietic lineage cell-specific protein | chr3 | Not Cancer Driver | No | 1 | hippie | 103 | 446 | 94 | 94 | 0 |
| HDAC1 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 47 | 135 | 10 | 10 | 0 |
| HDAC4 | HDAC4 | P56524 | Histone deacetylase 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 182 | 749 | 132 | 132 | 0 |
| HDAC8 | HDAC8 | Q9BY41 | Histone deacetylase 8 | chrX | Not Cancer Driver | No | 1 | hippie | 54 | 32 | 4 | 4 | 4 |
| HEXIM1 | HEXIM1 | O94992 | Protein HEXIM1 | chr17 | Not Cancer Driver | No | 1 | hippie | 40 | 352 | 40 | 40 | 0 |
| HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | Census | Yes | 2 | hippie, biogrid | 118 | 435 | 51 | 51 | 0 |
| HIP1R | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | Not Cancer Driver | No | 1 | hippie | 94 | 524 | 34 | 34 | 0 |
| HLX | HLX | Q14774 | H2.0-like homeobox protein | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 107 | 412 | 98 | 98 | 0 |
| HSPB2 | HSPB2 | Q16082 | Heat shock protein beta-2 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 25 | 103 | 11 | 11 | 0 |
| HTRA2 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | Compendium | Yes | 1 | hippie | 44 | 127 | 9 | 9 | 2 |
| HTT | HTT | P42858 | Huntingtin | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 336 | 666 | 69 | 69 | 2 |
| IL2RB | IL2RB | P14784 | Interleukin-2 receptor subunit beta | chr22 | Not Cancer Driver | No | 1 | hippie | 81 | 182 | 33 | 33 | 1 |
| INCA1_ENST00000576820 | INCA1 | Q0VD86 | Protein INCA1 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 18 | 195 | 14 | 14 | 0 |
| IQGAP1 | IQGAP1 | P46940 | Ras GTPase-activating-like protein IQGAP1 | chr15 | Not Cancer Driver | No | 1 | hippie | 183 | 351 | 35 | 35 | 0 |
| ISG15 | ISG15 | P05161 | Ubiquitin-like protein ISG15 | chr1 | Not Cancer Driver | No | 1 | hippie | 12 | 24 | 2 | 2 | 0 |
| ITGA2 | ITGA2 | P17301 | Integrin alpha-2 | chr5 | Not Cancer Driver | No | 1 | hippie | 166 | 26 | 0 | 0 | 0 |
| ITPKA | ITPKA | P23677 | Inositol-trisphosphate 3-kinase A | chr15 | Not Cancer Driver | No | 1 | hippie | 28 | 216 | 7 | 7 | 0 |
| KAT5_ENST00000377046 | KAT5 | Q92993 | Histone acetyltransferase KAT5 | chr11 | Not Cancer Driver | No | 1 | hippie | 65 | 173 | 21 | 21 | 3 |
| KCNMA1 | KCNMA1 | Q12791 | Calcium-activated potassium channel subunit alpha-1 | chr10 | Not Cancer Driver | No | 1 | intact | 222 | 225 | 39 | 39 | 5 |
| KIF23 | KIF23 | Q02241 | Kinesin-like protein KIF23 | chr15 | Not Cancer Driver | No | 1 | hippie | 102 | 559 | 62 | 62 | 0 |
| KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | Census, Compendium | Yes | 1 | hippie | 226 | 83 | 33 | 33 | 21 |
| KLHL20 | KLHL20 | Q9Y2M5 | Kelch-like protein 20 | chr1 | Not Cancer Driver | No | 1 | hippie | 83 | 143 | 17 | 17 | 0 |
| KRT17 | KRT17 | Q04695 | Keratin, type I cytoskeletal 17 | chr17 | Not Cancer Driver | No | 1 | hippie | 86 | 160 | 31 | 31 | 18 |
| KRT40_ENST00000398486 | KRT40 | Q6A162 | Keratin, type I cytoskeletal 40 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 6 | 1 | 1 | 0 |
| LARP7_ENST00000344442 | LARP7 | Q4G0J3 | La-related protein 7 | chr4 | Not Cancer Driver | No | 1 | hippie | 58 | 350 | 44 | 44 | 0 |
| LASP1 | LASP1 | Q14847 | LIM and SH3 domain protein 1 | chr17 | Census | Yes | 1 | hippie | 29 | 198 | 24 | 24 | 0 |
| LATS1 | LATS1 | O95835 | Serine/threonine-protein kinase LATS1 | chr6 | Census, Compendium | Yes | 1 | hippie, biogrid | 161 | 788 | 100 | 100 | 0 |
| LGALS3 | LGALS3 | P17931 | Galectin-3 | chr14 | Not Cancer Driver | No | 1 | hippie | 15 | 133 | 6 | 6 | 0 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | Not Cancer Driver | No | 1 | hippie | 54 | 65 | 16 | 16 | 0 |
| LIMA1_ENST00000341247 | LIMA1 | Q9UHB6 | LIM domain and actin-binding protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 88 | 687 | 81 | 81 | 0 |
| LRCH3_ENST00000425562 | LRCH3 | Q96II8 | DISP complex protein LRCH3 | chr3 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 101 | 415 | 55 | 55 | 0 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
| LRSAM1_ENST00000373322 | LRSAM1 | Q6UWE0 | E3 ubiquitin-protein ligase LRSAM1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 240 | 30 | 30 | 1 |
| MACF1_ENST00000372915 | MACF1 | Q9UPN3 | Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 | chr1 | Not Cancer Driver | No | 1 | hippie | 877 | 2826 | 334 | 334 | 4 |
| MAEA | MAEA | Q7L5Y9 | E3 ubiquitin-protein transferase MAEA | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 64 | 5 | 5 | 0 |
| MAK16 | MAK16 | Q9BXY0 | Protein MAK16 homolog | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 130 | 19 | 19 | 0 |
| MAP1A | MAP1A | P78559 | Microtubule-associated protein 1A | chr15 | Not Cancer Driver | No | 1 | hippie | 369 | 2443 | 311 | 311 | 0 |
| MAPK14_ENST00000229794 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | Not Cancer Driver | No | 1 | hippie | 39 | 25 | 1 | 1 | 0 |
| MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | Not Cancer Driver | No | 1 | hippie | 128 | 750 | 126 | 126 | 18 |
| MARK4 | MARK4 | Q96L34 | MAP/microtubule affinity-regulating kinase 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 94 | 403 | 46 | 46 | 0 |
| MCM2 | MCM2 | P49736 | DNA replication licensing factor MCM2 | chr3 | Not Cancer Driver | No | 1 | hippie | 104 | 275 | 38 | 38 | 1 |
| MECOM_ENST00000494292 | MECOM | Q03112 | Histone-lysine N-methyltransferase MECOM | chr3 | Census, Compendium | Yes | 1 | hippie, biogrid | 287 | 749 | 159 | 159 | 3 |
| MEPCE | MEPCE | Q7L2J0 | 7SK snRNA methylphosphate capping enzyme | chr7 | Not Cancer Driver | No | 1 | hippie | 76 | 446 | 42 | 42 | 0 |
| MIB2_ENST00000504599 | MIB2 | Q96AX9 | E3 ubiquitin-protein ligase MIB2 | chr1 | Not Cancer Driver | No | 1 | hippie | 88 | 307 | 31 | 31 | 0 |
| MINPP1 | MINPP1 | Q9UNW1 | Multiple inositol polyphosphate phosphatase 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 52 | 46 | 2 | 2 | 2 |
| MLPH | MLPH | Q9BV36 | Melanophilin | chr2 | Not Cancer Driver | No | 2 | intact, hippie | 78 | 463 | 57 | 57 | 1 |
| MORF4L1 | MORF4L1 | Q9UBU8 | Mortality factor 4-like protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 43 | 163 | 17 | 17 | 0 |
| MORF4L2_ENST00000433176 | MORF4L2 | Q15014 | Mortality factor 4-like protein 2 | chrX | Not Cancer Driver | No | 1 | hippie | 44 | 136 | 21 | 21 | 0 |
| MRGBP | MRGBP | Q9NV56 | MRG/MORF4L-binding protein | chr20 | Not Cancer Driver | No | 1 | hippie | 27 | 147 | 23 | 23 | 0 |
| MRPS5 | MRPS5 | P82675 | 28S ribosomal protein S5, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 157 | 20 | 20 | 0 |
| MTRF1 | MTRF1 | O75570 | Peptide chain release factor 1, mitochondrial | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 71 | 9 | 9 | 0 |
| MYBPC1_ENST00000550270 | MYBPC1 | Q00872 | Myosin-binding protein C, slow-type | chr12 | Not Cancer Driver | No | 1 | intact | 227 | 220 | 38 | 38 | 7 |
| MYH9 | MYH9 | P35579 | Myosin-9 | chr22 | Census, Compendium | Yes | 1 | hippie | 310 | 1120 | 160 | 160 | 17 |
| MYLK | MYLK | Q15746 | Myosin light chain kinase, smooth muscle | chr3 | Not Cancer Driver | No | 1 | hippie | 343 | 957 | 184 | 184 | 3 |
| MYO10 | MYO10 | Q9HD67 | Unconventional myosin-X | chr5 | Not Cancer Driver | No | 2 | intact, hippie | 296 | 418 | 59 | 59 | 0 |
| MYO18A | MYO18A | Q92614 | Unconventional myosin-XVIIIa | chr17 | Not Cancer Driver | No | 1 | hippie | 268 | 1237 | 176 | 176 | 0 |
| MYO1C | MYO1C | O00159 | Unconventional myosin-Ic | chr17 | Not Cancer Driver | No | 2 | intact, hippie | 110 | 66 | 11 | 11 | 0 |
| MYO6 | MYO6 | Q9UM54 | Unconventional myosin-VI | chr6 | Not Cancer Driver | No | 1 | hippie | 176 | 342 | 41 | 41 | 3 |
| MYO7A | MYO7A | Q13402 | Unconventional myosin-VIIa | chr11 | Not Cancer Driver | No | 1 | hippie | 298 | 369 | 58 | 58 | 50 |
| MYO9B_ENST00000594824 | MYO9B | Q13459 | Unconventional myosin-IXb | chr19 | Not Cancer Driver | No | 1 | hippie | 226 | 827 | 80 | 80 | 0 |
| NAA40 | NAA40 | Q86UY6 | N-alpha-acetyltransferase 40 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 30 | 3 | 3 | 0 |
| NCKAP1_ENST00000361354 | NCKAP1 | Q9Y2A7 | Nck-associated protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 129 | 44 | 3 | 3 | 0 |
| NCOA3 | NCOA3 | Q9Y6Q9 | Nuclear receptor coactivator 3 | chr20 | Not Cancer Driver | No | 1 | hippie | 176 | 1231 | 160 | 160 | 0 |
| NCSTN | NCSTN | Q92542 | Nicastrin | chr1 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 94 | 72 | 11 | 11 | 1 |
| NEK4 | NEK4 | P51957 | Serine/threonine-protein kinase Nek4 | chr3 | Not Cancer Driver | No | 1 | hippie | 78 | 492 | 49 | 49 | 0 |
| NEXN | NEXN | Q0ZGT2 | Nexilin | chr1 | Not Cancer Driver | No | 1 | hippie | 111 | 614 | 102 | 102 | 4 |
| NMI | NMI | Q13287 | N-myc-interactor | chr2 | Not Cancer Driver | No | 1 | hippie | 34 | 104 | 12 | 12 | 0 |
| NMRAL1 | NMRAL1 | Q9HBL8 | NmrA-like family domain-containing protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 14 | 3 | 3 | 0 |
| NR3C2_ENST00000344721 | NR3C2 | P08235 | Mineralocorticoid receptor | chr4 | Not Cancer Driver | No | 1 | hippie | 168 | 484 | 88 | 88 | 14 |
| NRAP_ENST00000359988 | NRAP | Q86VF7 | Nebulin-related-anchoring protein | chr10 | Not Cancer Driver | No | 1 | hippie | 302 | 706 | 139 | 139 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
| OBSL1 | OBSL1 | O75147 | Obscurin-like protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 233 | 553 | 60 | 60 | 0 |
| OCLN | OCLN | Q16625 | Occludin | chr5 | Not Cancer Driver | No | 1 | hippie | 54 | 244 | 21 | 21 | 1 |
| OCRL | OCRL | Q01968 | Inositol polyphosphate 5-phosphatase OCRL | chrX | Not Cancer Driver | No | 1 | hippie | 151 | 126 | 24 | 24 | 41 |
| PAGE4_ENST00000376141 | PAGE4 | O60829 | P antigen family member 4 | chrX | Not Cancer Driver | No | 1 | hippie | 20 | 102 | 20 | 20 | 0 |
| PAK1_ENST00000356341 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 57 | 299 | 30 | 30 | 2 |
| PCLAF | PCLAF | Q15004 | PCNA-associated factor | chr15 | Not Cancer Driver | No | 1 | hippie | 20 | 111 | 20 | 20 | 0 |
| PCYT1B | PCYT1B | Q9Y5K3 | Choline-phosphate cytidylyltransferase B | chrX | Not Cancer Driver | No | 1 | hippie | 60 | 171 | 17 | 17 | 0 |
| PFDN1 | PFDN1 | O60925 | Prefoldin subunit 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 8 | 42 | 4 | 4 | 0 |
| PFN1 | PFN1 | P07737 | Profilin-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 16 | 7 | 1 | 1 | 3 |
| PHACTR1 | PHACTR1 | Q9C0D0 | Phosphatase and actin regulator 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 81 | 447 | 59 | 59 | 3 |
| PIH1D1 | PIH1D1 | Q9NWS0 | PIH1 domain-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 157 | 13 | 13 | 0 |
| PIK3R1 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | Census, Compendium | Yes | 1 | hippie | 154 | 268 | 61 | 61 | 2 |
| PLD1 | PLD1 | Q13393 | Phospholipase D1 | chr3 | Not Cancer Driver | No | 1 | hippie | 181 | 133 | 32 | 32 | 1 |
| PNMA5_ENST00000452693 | PNMA5 | Q96PV4 | Paraneoplastic antigen-like protein 5 | chrX | Not Cancer Driver | No | 1 | hippie | 84 | 163 | 31 | 31 | 0 |
| POLR1B_ENST00000263331 | POLR1B | Q9H9Y6 | DNA-directed RNA polymerase I subunit RPA2 | chr2 | Not Cancer Driver | No | 1 | hippie | 120 | 69 | 10 | 10 | 2 |
| POU5F1 | POU5F1 | Q01860 | POU domain, class 5, transcription factor 1 | chr6 | Census | Yes | 1 | hippie | 36 | 186 | 12 | 12 | 0 |
| PPM1B | PPM1B | O75688 | Protein phosphatase 1B | chr2 | Not Cancer Driver | No | 1 | hippie | 65 | 243 | 31 | 31 | 0 |
| PPP1CA_ENST00000376745 | PPP1CA | P62136 | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | chr11 | Not Cancer Driver | No | 1 | hippie | 38 | 27 | 6 | 6 | 0 |
| PPP1CB_ENST00000358506 | PPP1CB | P62140 | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | chr2 | Not Cancer Driver | No | 1 | hippie | 47 | 25 | 5 | 5 | 5 |
| PPP1R1A | PPP1R1A | Q13522 | Protein phosphatase 1 regulatory subunit 1A | chr12 | Not Cancer Driver | No | 3 | hippie, biogrid | 24 | 171 | 24 | 24 | 0 |
| PPP1R9B | PPP1R9B | Q96SB3 | Neurabin-2 | chr17 | Not Cancer Driver | No | 1 | hippie | 47 | 695 | 35 | 35 | 0 |
| PRKCA | PRKCA | P17252 | Protein kinase C alpha type | chr17 | Not Cancer Driver | No | 1 | hippie | 94 | 154 | 22 | 22 | 0 |
| PRKCD_ENST00000330452 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | Compendium | Yes | 1 | hippie | 79 | 43 | 9 | 9 | 0 |
| PRKCE | PRKCE | Q02156 | Protein kinase C epsilon type | chr2 | Not Cancer Driver | No | 1 | hippie | 107 | 170 | 26 | 26 | 0 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | Not Cancer Driver | No | 1 | hippie | 110 | 78 | 15 | 15 | 31 |
| PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 49 | 140 | 25 | 25 | 0 |
| PTPN22 | PTPN22 | Q9Y2R2 | Tyrosine-protein phosphatase non-receptor type 22 | chr1 | Not Cancer Driver | No | 1 | hippie | 141 | 364 | 62 | 62 | 4 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
| RAD18 | RAD18 | Q9NS91 | E3 ubiquitin-protein ligase RAD18 | chr3 | Not Cancer Driver | No | 1 | hippie | 59 | 328 | 43 | 43 | 0 |
| RAVER1_ENST00000615032 | RAVER1 | Q8IY67 | Ribonucleoprotein PTB-binding 1 | chr19 | Not Cancer Driver | No | 1 | intact | 61 | 330 | 22 | 22 | 0 |
| RC3H1_ENST00000258349 | RC3H1 | Q5TC82 | Roquin-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 158 | 796 | 115 | 115 | 0 |
| RC3H2_ENST00000357244 | RC3H2 | Q9HBD1 | Roquin-2 | chr9 | Not Cancer Driver | No | 1 | hippie | 128 | 703 | 81 | 81 | 0 |
| RELA | RELA | Q04206 | Transcription factor p65 | chr11 | Compendium | Yes | 1 | hippie | 75 | 400 | 48 | 48 | 0 |
| RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 19 | 2 | 2 | 0 |
| RNF167_ENST00000571816 | RNF167 | Q9H6Y7 | E3 ubiquitin-protein ligase RNF167 | chr17 | Not Cancer Driver | No | 1 | hippie | 35 | 102 | 18 | 18 | 0 |
| RPS6KB1 | RPS6KB1 | P23443 | Ribosomal protein S6 kinase beta-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 45 | 226 | 26 | 26 | 0 |
| RPS6KB2 | RPS6KB2 | Q9UBS0 | Ribosomal protein S6 kinase beta-2 | chr11 | Not Cancer Driver | No | 1 | hippie | 54 | 194 | 16 | 16 | 0 |
| RRN3 | RRN3 | Q9NYV6 | RNA polymerase I-specific transcription initiation factor RRN3 | chr16 | Not Cancer Driver | No | 1 | hippie | 66 | 115 | 15 | 15 | 0 |
| RSPH6A | RSPH6A | Q9H0K4 | Radial spoke head protein 6 homolog A | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 129 | 483 | 94 | 94 | 0 |
| S100A1 | S100A1 | P23297 | Protein S100-A1 | chr1 | Not Cancer Driver | No | 1 | hippie | 13 | 9 | 0 | 0 | 0 |
| S100A4_ENST00000354332 | S100A4 | P26447 | Protein S100-A4 | chr1 | Not Cancer Driver | No | 1 | hippie | 9 | 6 | 2 | 2 | 0 |
| SCIN | SCIN | Q9Y6U3 | Scinderin | chr7 | Not Cancer Driver | No | 1 | hippie | 100 | 170 | 35 | 35 | 0 |
| SFN | SFN | P31947 | 14-3-3 protein sigma | chr1 | Not Cancer Driver | No | 1 | hippie | 27 | 75 | 9 | 9 | 0 |
| SHC1_ENST00000368445 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 84 | 397 | 58 | 58 | 0 |
| SLC16A10 | SLC16A10 | Q8TF71 | Monocarboxylate transporter 10 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 82 | 2 | 2 | 0 |
| SLC39A3 | SLC39A3 | Q9BRY0 | Zinc transporter ZIP3 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 0 | 0 | 0 | 0 |
| SMARCA4 | SMARCA4 | P51532 | Transcription activator BRG1 | chr19 | Census, Compendium | Yes | 1 | hippie | 349 | 1072 | 195 | 195 | 5 |
| SMARCB1_ENST00000644036 | SMARCB1 | Q12824 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | chr22 | Census, Compendium | Yes | 1 | hippie | 64 | 141 | 35 | 35 | 3 |
| SMARCD1 | SMARCD1 | Q96GM5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 | chr12 | Census, Compendium | Yes | 1 | hippie | 48 | 216 | 18 | 18 | 2 |
| SMTN_ENST00000347557 | SMTN | P53814 | Smoothelin | chr22 | Not Cancer Driver | No | 1 | hippie | 121 | 755 | 93 | 93 | 0 |
| SMURF2 | SMURF2 | Q9HAU4 | E3 ubiquitin-protein ligase SMURF2 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 87 | 242 | 28 | 28 | 0 |
| SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | Not Cancer Driver | No | 1 | hippie | 21 | 107 | 13 | 13 | 5 |
| SORBS1_ENST00000361941 | SORBS1 | Q9BX66 | Sorbin and SH3 domain-containing protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 161 | 1111 | 133 | 133 | 0 |
| SORBS3 | SORBS3 | O60504 | Vinexin | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 577 | 56 | 56 | 0 |
| SPIRE1 | SPIRE1 | Q08AE8 | Protein spire homolog 1 | chr18 | Not Cancer Driver | No | 1 | intact | 78 | 414 | 48 | 48 | 0 |
| SPRR1A | SPRR1A | P35321 | Cornifin-A | chr1 | Not Cancer Driver | No | 1 | hippie | 26 | 82 | 25 | 25 | 0 |
| SPTA1_ENST00000368147 | SPTA1 | P02549 | Spectrin alpha chain, erythrocytic 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 1046 | 707 | 294 | 294 | 21 |
| SPTAN1_ENST00000372731 | SPTAN1 | Q13813 | Spectrin alpha chain, non-erythrocytic 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 315 | 980 | 114 | 114 | 0 |
| SPTBN2 | SPTBN2 | O15020 | Spectrin beta chain, non-erythrocytic 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 317 | 877 | 126 | 126 | 2 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | Census | Yes | 1 | hippie | 53 | 130 | 11 | 11 | 1 |
| SSH1 | SSH1 | Q8WYL5 | Protein phosphatase Slingshot homolog 1 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 129 | 658 | 85 | 85 | 0 |
| SSH3 | SSH3 | Q8TE77 | Protein phosphatase Slingshot homolog 3 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 96 | 354 | 49 | 49 | 0 |
| STYXL1_ENST00000359697 | STYXL1 | Q9Y6J8 | Serine/threonine/tyrosine-interacting-like protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 55 | 18 | 3 | 3 | 0 |
| SUMO3_ENST00000332859 | SUMO3 | P55854 | Small ubiquitin-related modifier 3 | chr21 | Not Cancer Driver | No | 1 | hippie | 7 | 87 | 5 | 5 | 0 |
| SVIL | SVIL | O95425 | Supervillin | chr10 | Not Cancer Driver | No | 1 | intact | 308 | 1423 | 192 | 192 | 0 |
| SYNC | SYNC | Q9H7C4 | Syncoilin | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 358 | 22 | 22 | 0 |
| TAGLN_ENST00000530649 | TAGLN | Q01995 | Transgelin | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 94 | 12 | 12 | 0 |
| TCP1 | TCP1 | P17987 | T-complex protein 1 subunit alpha | chr6 | Not Cancer Driver | No | 2 | intact, hippie | 54 | 55 | 10 | 10 | 0 |
| TES | TES | Q9UGI8 | Testin | chr7 | Not Cancer Driver | No | 1 | hippie | 56 | 100 | 7 | 7 | 0 |
| TET2 | TET2 | Q6N021 | Methylcytosine dioxygenase TET2 | chr4 | Census, Compendium | Yes | 1 | hippie | 191 | 1663 | 176 | 176 | 1 |
| TEX101_ENST00000598265 | TEX101 | Q9BY14 | Testis-expressed protein 101 | chr19 | Not Cancer Driver | No | 1 | hippie | 45 | 2 | 0 | 0 | 0 |
| TFCP2 | TFCP2 | Q12800 | Alpha-globin transcription factor CP2 | chr12 | Not Cancer Driver | No | 1 | hippie | 68 | 169 | 23 | 23 | 0 |
| TIAF1 | MYO18A | O95411 | Putative TGFB1-induced anti-apoptotic factor 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 16 | 30 | 5 | 5 | 0 |
| TJP1_ENST00000346128 | TJP1 | Q07157 | Tight junction protein ZO-1 | chr15 | Not Cancer Driver | No | 1 | hippie | 198 | 1350 | 151 | 151 | 0 |
| TLE3 | TLE3 | Q04726 | Transducin-like enhancer protein 3 | chr15 | Not Cancer Driver | No | 2 | hippie, biogrid | 87 | 381 | 50 | 50 | 0 |
| TLN1 | TLN1 | Q9Y490 | Talin-1 | chr9 | Not Cancer Driver | No | 1 | hippie | 278 | 1109 | 126 | 126 | 0 |
| TMSB4X_ENST00000380633 | TMSB4X | P62328 | Thymosin beta-4 | chrX | Census | Yes | 1 | hippie | 7 | 44 | 7 | 7 | 0 |
| TMSB4Y | TMSB4Y | O14604 | Thymosin beta-4, Y-chromosomal | chrY | Not Cancer Driver | No | 1 | hippie | 1 | 44 | 1 | 1 | 0 |
| TNIP2 | TNIP2 | Q8NFZ5 | TNFAIP3-interacting protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 43 | 316 | 36 | 36 | 0 |
| TNNI1_ENST00000336092 | TNNI1 | P19237 | Troponin I, slow skeletal muscle | chr1 | Not Cancer Driver | No | 1 | hippie | 34 | 72 | 8 | 8 | 0 |
| TNNI3 | TNNI3 | P19429 | Troponin I, cardiac muscle | chr19 | Not Cancer Driver | No | 1 | hippie | 42 | 108 | 19 | 19 | 21 |
| TNNI3K | TNNI3K | Q59H18 | Serine/threonine-protein kinase TNNI3K | chr1 | Not Cancer Driver | No | 1 | hippie | 234 | 78 | 26 | 26 | 1 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
| TPM1_ENST00000403994 | TPM1 | P09493 | Tropomyosin alpha-1 chain | chr15 | Not Cancer Driver | No | 1 | intact | 33 | 234 | 29 | 29 | 8 |
| TPM2 | TPM2 | P07951 | Tropomyosin beta chain | chr9 | Not Cancer Driver | No | 1 | hippie | 39 | 232 | 35 | 35 | 15 |
| TPM3 | TPM3 | P06753 | Tropomyosin alpha-3 chain | chr1 | Census | Yes | 1 | hippie | 35 | 230 | 27 | 27 | 21 |
| TPT1_ENST00000530705 | TPT1 | P13693 | Translationally-controlled tumor protein | chr13 | Not Cancer Driver | No | 1 | intact, hippie | 17 | 43 | 6 | 6 | 0 |
| TRAF3IP1 | TRAF3IP1 | Q8TDR0 | TRAF3-interacting protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 75 | 507 | 60 | 60 | 4 |
| TRAF3_ENST00000392745 | TRAF3 | Q13114 | TNF receptor-associated factor 3 | chr14 | Compendium | Yes | 1 | hippie | 61 | 101 | 9 | 9 | 1 |
| TRIM37 | TRIM37 | O94972 | E3 ubiquitin-protein ligase TRIM37 | chr17 | Not Cancer Driver | No | 1 | hippie | 119 | 492 | 60 | 60 | 3 |
| TRIM55 | TRIM55 | Q9BYV6 | Tripartite motif-containing protein 55 | chr8 | Not Cancer Driver | No | 1 | hippie | 134 | 276 | 78 | 78 | 0 |
| TRIM63 | TRIM63 | Q969Q1 | E3 ubiquitin-protein ligase TRIM63 | chr1 | Not Cancer Driver | No | 1 | hippie | 47 | 71 | 13 | 13 | 0 |
| TRIM6_ENST00000278302 | TRIM6 | Q9C030 | Tripartite motif-containing protein 6 | chr11 | Not Cancer Driver | No | 1 | hippie | 86 | 47 | 15 | 15 | 0 |
| TRIP6 | TRIP6 | Q15654 | Thyroid receptor-interacting protein 6 | chr7 | Not Cancer Driver | No | 1 | hippie | 62 | 268 | 19 | 19 | 0 |
| TSC1 | TSC1 | Q92574 | Hamartin | chr9 | Census, Compendium | Yes | 1 | hippie | 135 | 732 | 78 | 78 | 11 |
| TSPAN33 | TSPAN33 | Q86UF1 | Tetraspanin-33 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 0 | 0 | 0 | 0 |
| TTN_ENST00000615779 | TTN | Q8WZ42 | Titin | chr2 | Not Cancer Driver | No | 1 | hippie | 7917 | 12926 | 2861 | 2861 | 10 |
| TWF1_ENST00000395510 | TWF1 | Q12792 | Twinfilin-1 | chr12 | Not Cancer Driver | No | 1 | intact | 50 | 52 | 3 | 3 | 0 |
| UBAC2 | UBAC2 | Q8NBM4 | Ubiquitin-associated domain-containing protein 2 | chr13 | Not Cancer Driver | No | 1 | hippie | 33 | 57 | 9 | 9 | 0 |
| UBE3A | UBE3A | Q05086 | Ubiquitin-protein ligase E3A | chr15 | Not Cancer Driver | No | 1 | hippie | 141 | 136 | 22 | 22 | 0 |
| UBL4A | UBL4A | P11441 | Ubiquitin-like protein 4A | chrX | Not Cancer Driver | No | 1 | hippie | 22 | 16 | 5 | 5 | 0 |
| USP25_ENST00000285679 | USP25 | Q9UHP3 | Ubiquitin carboxyl-terminal hydrolase 25 | chr21 | Not Cancer Driver | No | 1 | hippie | 135 | 354 | 55 | 55 | 0 |
| USP6NL_ENST00000609104 | USP6NL | Q92738 | USP6 N-terminal-like protein | chr10 | Not Cancer Driver | No | 1 | hippie | 113 | 472 | 81 | 81 | 0 |
| UTRN | UTRN | P46939 | Utrophin | chr6 | Not Cancer Driver | No | 1 | hippie | 476 | 1283 | 183 | 183 | 0 |
| VASP | VASP | P50552 | Vasodilator-stimulated phosphoprotein | chr19 | Not Cancer Driver | No | 1 | hippie | 39 | 335 | 34 | 34 | 0 |
| VAV1 | VAV1 | P15498 | Proto-oncogene vav | chr19 | Census, Compendium | Yes | 1 | hippie | 165 | 113 | 19 | 19 | 0 |
| VCL | VCL | P18206 | Vinculin | chr10 | Not Cancer Driver | No | 2 | intact, hippie | 114 | 673 | 80 | 80 | 2 |
| VIL1 | VIL1 | P09327 | Villin-1 | chr2 | Not Cancer Driver | No | 2 | intact, hippie | 124 | 222 | 38 | 38 | 0 |
| VIM_ENST00000224237 | VIM | P08670 | Vimentin | chr10 | Not Cancer Driver | No | 1 | hippie | 84 | 316 | 57 | 57 | 1 |
| VRK3_ENST00000594948 | VRK3 | Q8IV63 | Inactive serine/threonine-protein kinase VRK3 | chr19 | Not Cancer Driver | No | 1 | hippie | 65 | 180 | 18 | 18 | 0 |
| WASF1_ENST00000392586 | WASF1 | Q92558 | Wiskott-Aldrich syndrome protein family member 1 | chr6 | Not Cancer Driver | No | 2 | intact | 63 | 445 | 49 | 49 | 0 |
| WASHC1 | WASHC1 | A8K0Z3 | WASH complex subunit 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 6 | 336 | 6 | 6 | 0 |
| WASL | WASL | O00401 | Neural Wiskott-Aldrich syndrome protein | chr7 | Not Cancer Driver | No | 2 | intact | 72 | 394 | 57 | 57 | 0 |
| WIPF1_ENST00000359761 | WIPF1 | O43516 | WAS/WASL-interacting protein family member 1 | chr2 | Not Cancer Driver | No | 1 | intact | 110 | 503 | 110 | 110 | 0 |
| XIRP1 | XIRP1 | Q702N8 | Xin actin-binding repeat-containing protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 326 | 1660 | 301 | 301 | 0 |
| XPO6 | XPO6 | Q96QU8 | Exportin-6 | chr16 | Not Cancer Driver | No | 1 | hippie | 133 | 29 | 1 | 1 | 0 |
| YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | Not Cancer Driver | No | 1 | hippie | 51 | 489 | 49 | 49 | 0 |
| YWHAZ_ENST00000395956 | YWHAZ | P63104 | 14-3-3 protein zeta/delta | chr8 | Not Cancer Driver | No | 1 | hippie | 30 | 81 | 10 | 10 | 0 |
| ZNF16 | ZNF16 | P17020 | Zinc finger protein 16 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 99 | 293 | 40 | 40 | 0 |
| ZNF20 | ZNF20 | P17024 | Zinc finger protein 20 | chr19 | Not Cancer Driver | No | 1 | hippie | 63 | 90 | 18 | 18 | 0 |
| ZNF213 | ZNF213 | O14771 | Zinc finger protein 213 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 292 | 38 | 38 | 0 |
| ZNF324B | ZNF324B | Q6AW86 | Zinc finger protein 324B | chr19 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 87 | 266 | 40 | 40 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|