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ACOT7 ,ACOT7 ,O00154
  • Number of Interaction partner in intact: 17
  • Number of Interaction partner in biogrid: 19
  • Number of Interaction partner in hippie: 91
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACOT12 ACOT12 Q8WYK0 Acetyl-coenzyme A thioesterase chr5 Not Cancer Driver No 1 intact, hippie 93 41 3 3 0
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
ALDH9A1 ALDH9A1 P49189 4-trimethylaminobutyraldehyde dehydrogenase chr1 Not Cancer Driver No 1 hippie 57 16 0 0 0
ANK2 ANK2 Q01484 Ankyrin-2 chr4 Not Cancer Driver No 1 hippie 770 2844 566 566 4
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 Not Cancer Driver No 1 hippie 66 23 5 5 2
ATXN1 ATXN1 P54253 Ataxin-1 chr6 Not Cancer Driver No 1 hippie 193 604 168 168 0
ATXN1L ATXN1L P0C7T5 Ataxin-1-like chr16 Not Cancer Driver No 1 hippie 30 476 19 19 0
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 Not Cancer Driver No 1 intact, hippie 55 402 49 49 0
BOLA1_ENST00000369150 BOLA1 Q9Y3E2 BolA-like protein 1 chr1 Not Cancer Driver No 1 hippie 27 71 11 11 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 2 intact, hippie, biogrid 80 45 4 4 0
CAB39L_ENST00000347776 CAB39L Q9H9S4 Calcium-binding protein 39-like chr13 Not Cancer Driver No 3 intact, hippie, biogrid 41 38 2 2 0
CADPS CADPS Q9ULU8 Calcium-dependent secretion activator 1 chr3 Not Cancer Driver No 1 hippie, biogrid 298 336 71 71 0
CAMK2B CAMK2B Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta chr7 Not Cancer Driver No 2 intact, hippie 86 273 28 28 6
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie 30 2 0 0 0
CD247 CD247 P20963 T-cell surface glycoprotein CD3 zeta chain chr1 Not Cancer Driver No 1 hippie 33 91 24 24 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 hippie 287 145 18 18 151
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 Not Cancer Driver No 1 hippie 328 1411 148 148 0
COIL COIL P38432 Coilin chr17 Not Cancer Driver No 1 hippie, biogrid 61 385 42 42 0
COQ5 COQ5 Q5HYK3 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial chr12 Not Cancer Driver No 1 hippie 45 15 2 2 0
COQ9 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 hippie 43 111 13 13 0
CRYAB_ENST00000616970 CRYAB P02511 Alpha-crystallin B chain chr11 Not Cancer Driver No 1 hippie 22 59 11 11 4
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 hippie 123 167 23 23 3
DAZAP2_ENST00000412716 DAZAP2 Q15038 DAZ-associated protein 2 chr12 Not Cancer Driver No 1 hippie 17 68 7 7 0
DCTD_ENST00000438320 DCTD P32321 Deoxycytidylate deaminase chr4 Not Cancer Driver No 1 intact, hippie 33 3 0 0 0
DHRS4L2 DHRS4L2 Q6PKH6 Dehydrogenase/reductase SDR family member 4-like 2 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 24 32 4 4 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 Not Cancer Driver No 1 hippie 331 922 237 237 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 Not Cancer Driver No 1 hippie 34 15 5 5 0
DUSP4 DUSP4 Q13115 Dual specificity protein phosphatase 4 chr8 Not Cancer Driver No 1 hippie 43 63 9 9 0
ENKD1 ENKD1 Q9H0I2 Enkurin domain-containing protein 1 chr16 Not Cancer Driver No 1 intact, hippie 40 307 34 34 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 Not Cancer Driver No 1 hippie 182 140 24 24 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX Not Cancer Driver No 1 hippie 124 327 70 70 3
FOXI2 FOXI2 Q6ZQN5 Forkhead box protein I2 chr10 Not Cancer Driver No 1 hippie 32 165 22 22 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 hippie 88 312 53 53 0
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 hippie 39 24 3 3 0
GDI1 GDI1 P31150 Rab GDP dissociation inhibitor alpha chrX Not Cancer Driver No 1 hippie 69 34 6 6 2
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HOXA1_ENST00000643460 HOXA1 P49639 Homeobox protein Hox-A1 chr7 Not Cancer Driver No 1 hippie 90 262 68 68 0
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX Not Cancer Driver No 1 hippie, biogrid 27 15 3 3 11
KDSR KDSR Q06136 3-ketodihydrosphingosine reductase chr18 Census Yes 1 hippie, biogrid 31 35 4 4 1
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MAGEA3 MAGEA3 P43357 Melanoma-associated antigen 3 chrX Not Cancer Driver No 1 intact, hippie 79 103 18 18 0
MAGEA6 MAGEA6 P43360 Melanoma-associated antigen 6 chrX Not Cancer Driver No 1 hippie 95 103 20 20 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 hippie, biogrid 104 333 66 66 6
MDP1 MDP1 Q86V88 Magnesium-dependent phosphatase 1 chr14 Not Cancer Driver No 1 hippie 25 35 8 8 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYLK MYLK Q15746 Myosin light chain kinase, smooth muscle chr3 Not Cancer Driver No 1 hippie, biogrid 343 957 184 184 3
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NCOA5 NCOA5 Q9HCD5 Nuclear receptor coactivator 5 chr20 Not Cancer Driver No 1 hippie 84 478 70 70 0
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 hippie 123 117 42 42 0
NDRG1 NDRG1 Q92597 Protein NDRG1 chr8 Census Yes 1 hippie 66 140 22 22 0
NDUFS3 NDUFS3 O75489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial chr11 Not Cancer Driver No 1 hippie 34 26 3 3 2
NHLRC2 NHLRC2 Q8NBF2 NHL repeat-containing protein 2 chr10 Not Cancer Driver No 1 hippie 74 103 12 12 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 hippie 31 33 2 2 0
PCBP1 PCBP1 Q15365 Poly(rC)-binding protein 1 chr2 Census, Compendium Yes 1 hippie, biogrid 65 166 24 24 0
PDIA3 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 Not Cancer Driver No 1 hippie 57 98 11 11 0
PHYHIPL PHYHIPL Q96FC7 Phytanoyl-CoA hydroxylase-interacting protein-like chr10 Not Cancer Driver No 1 hippie, biogrid 49 68 9 9 0
PKNOX1 PKNOX1 P55347 Homeobox protein PKNOX1 chr21 Not Cancer Driver No 2 intact, hippie, biogrid 60 279 36 36 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 Census, Compendium Yes 1 hippie 113 31 6 6 9
POU6F1 POU6F1 A0A1C7CYV8 POU domain protein chr12 Not Cancer Driver No 1 hippie 55 397 34 34 0
PPM1K PPM1K Q8N3J5 Protein phosphatase 1K, mitochondrial chr4 Not Cancer Driver No 1 hippie 59 62 12 12 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 Compendium Yes 1 hippie, biogrid 118 246 34 34 0
RABGAP1L RABGAP1L Q5R372 Rab GTPase-activating protein 1-like chr1 Not Cancer Driver No 1 intact, hippie, biogrid 116 235 33 33 0
RAD51D_ENST00000394589 RAD51D O75771 DNA repair protein RAD51 homolog 4 chr17 Not Cancer Driver No 1 hippie, biogrid 34 49 10 10 0
RCC2 RCC2 Q9P258 Protein RCC2 chr1 Not Cancer Driver No 1 hippie 63 194 27 27 0
RELT RELT Q969Z4 Tumor necrosis factor receptor superfamily member 19L chr11 Not Cancer Driver No 3 intact, hippie, biogrid 48 239 18 18 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 Not Cancer Driver No 1 hippie, biogrid 44 33 2 2 0
RPS4Y1 RPS4Y1 P22090 40S ribosomal protein S4, Y isoform 1 chrY Not Cancer Driver No 1 hippie, biogrid 10 34 0 0 0
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 Not Cancer Driver No 1 hippie 110 440 72 72 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 1 hippie, biogrid 16 93 9 9 79
SORD SORD Q00796 Sorbitol dehydrogenase chr15 Not Cancer Driver No 1 hippie 29 41 7 7 3
SPATC1L SPATC1L Q9H0A9 Speriolin-like protein chr21 Not Cancer Driver No 1 intact, hippie 30 179 11 11 0
SST SST P61278 Somatostatin chr3 Not Cancer Driver No 1 hippie 25 40 15 15 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 Not Cancer Driver No 1 hippie 63 220 34 34 0
THAP1 THAP1 Q9NVV9 THAP domain-containing protein 1 chr8 Not Cancer Driver No 2 intact, hippie 19 76 8 8 45
TINF2 TINF2 Q9BSI4 TERF1-interacting nuclear factor 2 chr14 Not Cancer Driver No 1 hippie 38 190 17 17 4
TNFAIP8_ENST00000504771 TNFAIP8 O95379 Tumor necrosis factor alpha-induced protein 8 chr5 Not Cancer Driver No 1 hippie 21 13 1 1 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 Not Cancer Driver No 1 hippie 141 136 22 22 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 64 543 58 58 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 intact, hippie 82 581 79 79 8
UBXN1_ENST00000301935 UBXN1 Q04323 UBX domain-containing protein 1 chr11 Not Cancer Driver No 1 intact, hippie 35 271 33 33 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0
ZNF438 ZNF438 Q7Z4V0 Zinc finger protein 438 chr10 Not Cancer Driver No 1 intact, hippie 123 612 90 90 0