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ACADM_ENST00000370841 ,ACADM ,P11310
  • Uniprot Accession= P11310
  • Ensembl Transcript= ENST00000370841.8
  • Uniprot Name= ACADM
  • Name= Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 70
  • Number of Interaction partner in hippie: 118
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AASS AASS Q9UDR5 Alpha-aminoadipic semialdehyde synthase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 161 18 3 3 0
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 42 51 2 2 0
ACAD9 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 69 28 5 5 12
ACADM_ENST00000370841 ACADM P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial chr1 Not Cancer Driver No 1 hippie 61 41 5 5 19
AHSA1 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 46 146 17 17 0
ALDH9A1 ALDH9A1 P49189 4-trimethylaminobutyraldehyde dehydrogenase chr1 Not Cancer Driver No 1 hippie, biogrid 57 16 0 0 0
ANG ANG P03950 Angiogenin chr14 Not Cancer Driver No 1 hippie 19 36 2 2 14
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
AP1M1_ENST00000291439 AP1M1 Q9BXS5 AP-1 complex subunit mu-1 chr19 Not Cancer Driver No 1 hippie, biogrid 64 38 12 12 0
ARF1_ENST00000272102 ARF1 P84077 ADP-ribosylation factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 30 4 2 2 2
ARF4 ARF4 P18085 ADP-ribosylation factor 4 chr3 Not Cancer Driver No 1 hippie, biogrid 17 0 0 0 0
ARF5 ARF5 P84085 ADP-ribosylation factor 5 chr7 Not Cancer Driver No 1 hippie, biogrid 22 11 2 2 0
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 Census Yes 1 hippie, biogrid 115 115 16 16 6
ATP5F1C ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 Not Cancer Driver No 1 hippie 39 11 0 0 0
ATP6V1A ATP6V1A P38606 V-type proton ATPase catalytic subunit A chr3 Not Cancer Driver No 1 hippie, biogrid 86 31 2 2 4
ATP9A ATP9A O75110 Probable phospholipid-transporting ATPase IIA chr20 Not Cancer Driver No 1 hippie, biogrid 175 69 18 18 0
ATPAF1_ENST00000574428 ATPAF1 Q5TC12 ATP synthase mitochondrial F1 complex assembly factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 33 47 8 8 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie 51 63 8 8 0
BCAT1_ENST00000261192 BCAT1 P54687 Branched-chain-amino-acid aminotransferase, cytosolic chr12 Not Cancer Driver No 1 hippie, biogrid 67 8 2 2 0
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 19 115 15 15 7
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 161 88 7 7 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 hippie, biogrid 65 334 38 38 0
CCT6B CCT6B Q92526 T-complex protein 1 subunit zeta-2 chr17 Not Cancer Driver No 1 hippie, biogrid 90 1 0 0 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CLPP CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 Not Cancer Driver No 1 hippie 22 83 9 9 3
COX8A COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CS CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 50 13 2 2 0
CTSD CTSD P07339 Cathepsin D chr11 Not Cancer Driver No 1 hippie, biogrid 57 6 1 1 2
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 hippie 123 167 23 23 3
DDOST_ENST00000375048 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 hippie, biogrid 34 13 3 3 1
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie, biogrid 49 34 8 8 0
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 Not Cancer Driver No 1 hippie, biogrid 62 54 8 8 1
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 hippie 132 514 82 82 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 hippie, biogrid 37 153 16 16 0
DYNC1I1 DYNC1I1 O14576 Cytoplasmic dynein 1 intermediate chain 1 chr7 Not Cancer Driver No 1 hippie 146 255 60 60 0
ECHS1 ECHS1 P30084 Enoyl-CoA hydratase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 51 7 1 1 14
ETFA ETFA P13804 Electron transfer flavoprotein subunit alpha, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 30 34 2 2 3
ETFB_ENST00000309244 ETFB P38117 Electron transfer flavoprotein subunit beta chr19 Not Cancer Driver No 1 hippie 37 38 4 4 2
FAF2 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 1 hippie 54 171 16 16 0
FAXC FAXC Q5TGI0 Failed axon connections homolog chr6 Not Cancer Driver No 1 hippie, biogrid 47 54 11 11 0
FH FH P07954 Fumarate hydratase, mitochondrial chr1 Census, Compendium Yes 1 hippie, biogrid 67 76 5 5 13
FLNC FLNC Q14315 Filamin-C chr7 Not Cancer Driver No 1 hippie 546 1442 288 288 7
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GALE GALE Q14376 UDP-glucose 4-epimerase chr1 Not Cancer Driver No 1 hippie, biogrid 32 24 2 2 16
GFPT1 GFPT1 Q06210 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 chr2 Not Cancer Driver No 1 hippie, biogrid 81 75 8 8 13
GFPT2 GFPT2 O94808 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 chr5 Not Cancer Driver No 1 hippie, biogrid 121 42 8 8 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 47 135 10 10 0
HIBCH HIBCH Q6NVY1 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 42 26 0 0 1
HMOX2_ENST00000406590 HMOX2 P30519 Heme oxygenase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 27 74 10 10 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie, biogrid 94 268 35 35 0
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie, biogrid 80 351 24 24 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 20
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 61 82 6 6 2
IDH3A IDH3A P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 41 47 11 11 0
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 36 29 7 7 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie, biogrid 40 9 0 0 0
LDHB_ENST00000350669 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie, biogrid 47 15 2 2 11
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 131 18 2 2 1
MCUR1 MCUR1 Q96AQ8 Mitochondrial calcium uniporter regulator 1 chr6 Not Cancer Driver No 1 hippie, biogrid 30 65 0 0 0
MDH2 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 39 8 1 1 3
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 287 749 159 159 3
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie 76 446 42 42 0
METTL17_ENST00000339374 METTL17 Q9H7H0 Methyltransferase-like protein 17, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 62 95 16 16 0
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 Not Cancer Driver No 1 hippie 17 0 0 0 0
MRPS26 MRPS26 Q9BYN8 28S ribosomal protein S26, mitochondrial chr20 Not Cancer Driver No 1 hippie, biogrid 18 102 6 6 0
MTG2 MTG2 Q9H4K7 Mitochondrial ribosome-associated GTPase 2 chr20 Not Cancer Driver No 1 hippie, biogrid 57 47 9 9 0
MTRF1L MTRF1L Q9UGC7 Peptide chain release factor 1-like, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 31 183 12 12 0
NFS1 NFS1 Q9Y697 Cysteine desulfurase, mitochondrial chr20 Not Cancer Driver No 1 hippie, biogrid 46 72 9 9 1
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 hippie 50 10 5 5 0
PANK1 PANK1 Q8TE04 Pantothenate kinase 1 chr10 Not Cancer Driver No 1 hippie 62 248 17 17 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 hippie 52 50 10 10 0
PGD PGD P52209 6-phosphogluconate dehydrogenase, decarboxylating chr1 Not Cancer Driver No 1 hippie, biogrid 73 19 3 3 0
PMPCB PMPCB O75439 Mitochondrial-processing peptidase subunit beta chr7 Not Cancer Driver No 1 hippie, biogrid 55 22 3 3 5
PNKD PNKD Q8N490 Probable hydrolase PNKD chr2 Not Cancer Driver No 1 hippie 52 160 25 25 2
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 intact 38 27 6 6 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 1 hippie, biogrid 179 0 0 0 4
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 Not Cancer Driver No 1 hippie, biogrid 72 17 1 1 0
PRKCSH_ENST00000589838 PRKCSH P14314 Glucosidase 2 subunit beta chr19 Not Cancer Driver No 1 hippie, biogrid 68 320 41 41 0
PSMC2_ENST00000292644 PSMC2 P35998 26S proteasome regulatory subunit 7 chr7 Not Cancer Driver No 1 hippie, biogrid 63 120 13 13 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 22 58 4 4 0
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie, biogrid 50 69 3 3 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 37 214 37 37 0
SEC63 SEC63 Q9UGP8 Translocation protein SEC63 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 98 266 37 37 0
SLC25A3 SLC25A3 Q00325 Phosphate carrier protein, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 49 32 4 4 1
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 27 0 0 0 6
STRAP STRAP Q9Y3F4 Serine-threonine kinase receptor-associated protein chr12 Not Cancer Driver No 1 hippie 44 40 5 5 0
SUCLA2 SUCLA2 Q9P2R7 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 51 46 6 6 3
SUCLG2_ENST00000307227 SUCLG2 Q96I99 Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 48 12 2 2 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 7 87 5 5 0
SUMO4 SUMO4 Q6EEV6 Small ubiquitin-related modifier 4 chr6 Not Cancer Driver No 1 hippie 7 69 4 4 0
TECR TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 Not Cancer Driver No 1 hippie, biogrid 41 0 0 0 1
TEX101_ENST00000598265 TEX101 Q9BY14 Testis-expressed protein 101 chr19 Not Cancer Driver No 1 hippie 45 2 0 0 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TRMT61B TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 Not Cancer Driver No 1 hippie 48 123 10 10 0
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 37 73 7 7 0
TSFM_ENST00000454289 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 37 74 7 7 2
UBD UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 31 8 1 1 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
UBR5 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 Census, Compendium Yes 1 hippie 340 1296 162 162 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
UQCRC2 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 53 48 13 13 1
USP20_ENST00000358355 USP20 Q9Y2K6 Ubiquitin carboxyl-terminal hydrolase 20 chr9 Not Cancer Driver No 1 hippie, biogrid 112 295 36 36 0
USP50 USP50 Q70EL3 Inactive ubiquitin carboxyl-terminal hydrolase 50 chr15 Not Cancer Driver No 1 hippie, biogrid 33 2 0 0 0
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 38 36 4 4 0
VDAC2_ENST00000543351 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 35 9 1 1 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 hippie, biogrid 26 77 9 9 2
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0