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ABL2 ,ABL2 ,P42684
  • Uniprot Accession= P42684
  • Ensembl Transcript= ENST00000502732.5
  • Uniprot Name= ABL2
  • Name= Tyrosine-protein kinase ABL2
  • Chromosome= chr1
  • Driver status= Census, Compendium
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 28
  • Number of Interaction partner in hippie: 87
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 Census, Compendium Yes 1 hippie 55 360 39 39 0
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 2 hippie, biogrid 56 361 38 38 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 139 604 73 73 2
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 Census, Compendium Yes 1 hippie 171 641 70 70 0
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie, biogrid 196 443 88 88 169
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 Not Cancer Driver No 1 hippie 168 341 64 64 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 hippie, biogrid 29 195 9 9 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 17 112 9 9 0
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 3 hippie, biogrid 37 63 7 7 0
BCR BCR P11274 Breakpoint cluster region protein chr22 Census, Compendium Yes 1 hippie 146 603 69 69 0
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 Not Cancer Driver No 1 hippie 124 656 86 86 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 115 546 73 73 10
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie, biogrid 19 115 15 15 7
CASS4 CASS4 Q9NQ75 Cas scaffolding protein family member 4 chr20 Not Cancer Driver No 1 hippie 204 496 137 137 0
CAT CAT P04040 Catalase chr11 Not Cancer Driver No 1 hippie 70 176 18 18 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie 30 2 0 0 0
CD84 CD84 Q9UIB8 SLAM family member 5 chr1 Not Cancer Driver No 1 hippie 82 52 11 11 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 2 hippie, biogrid 52 214 31 31 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 2 hippie, biogrid 30 197 23 23 0
CRKL CRKL P46109 Crk-like protein chr22 Not Cancer Driver No 1 hippie, biogrid 38 160 25 25 0
CTTN_ENST00000301843 CTTN Q14247 Src substrate cortactin chr11 Not Cancer Driver No 1 hippie 78 465 56 56 0
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 64 102 2 2 0
DOK1 DOK1 Q99704 Docking protein 1 chr2 Not Cancer Driver No 1 hippie 50 294 31 31 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 Not Cancer Driver No 1 hippie 182 140 24 24 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 Not Cancer Driver No 1 hippie 186 119 17 17 7
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 2 hippie, biogrid 275 314 41 41 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 2 hippie, biogrid 298 396 70 70 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 Census, Compendium Yes 2 hippie, biogrid 428 323 116 116 2
FBXO38_ENST00000340253 FBXO38 Q6PIJ6 F-box only protein 38 chr5 Not Cancer Driver No 1 hippie 133 440 48 48 1
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 Census, Compendium Yes 1 hippie 200 64 27 27 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 Not Cancer Driver No 1 hippie 38 12 1 1 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 Not Cancer Driver No 1 hippie 112 124 25 25 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 107 16 4 4 18
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie, biogrid 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie, biogrid 100 254 43 43 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie, biogrid 24 200 13 13 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 93 286 38 38 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 2 hippie, biogrid 149 251 52 52 0
HSPBP1 HSPBP1 Q9NZL4 Hsp70-binding protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 29 130 7 7 0
JAK1 JAK1 P23458 Tyrosine-protein kinase JAK1 chr1 Census, Compendium Yes 1 hippie 147 120 7 7 2
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 Census, Compendium Yes 1 hippie, biogrid 226 83 33 33 21
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie, biogrid 788 7 2 2 27
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 Not Cancer Driver No 1 hippie, biogrid 26 12 1 1 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 Not Cancer Driver No 1 hippie 112 589 62 62 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MED28 MED28 Q9H204 Mediator of RNA polymerase II transcription subunit 28 chr4 Not Cancer Driver No 1 hippie 24 101 18 18 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 hippie, biogrid 226 62 15 15 19
MPIG6B MPIG6B O95866 Megakaryocyte and platelet inhibitory receptor G6b chr6 Not Cancer Driver No 1 hippie 37 61 7 7 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 2 hippie, biogrid 48 111 17 17 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 Not Cancer Driver No 3 hippie, biogrid 89 88 19 19 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie 150 711 79 79 0
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 Not Cancer Driver No 1 hippie 126 463 60 60 4
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
OIP5 OIP5 O43482 Protein Mis18-beta chr15 Not Cancer Driver No 1 hippie 31 65 7 7 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 Census, Compendium Yes 1 hippie 164 231 44 44 7
PECAM1 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 Not Cancer Driver No 1 hippie 2 153 2 2 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 hippie 154 268 61 61 2
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 Not Cancer Driver No 1 hippie 51 149 20 20 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie 158 186 21 21 0
PPP1R13L_ENST00000360957 PPP1R13L Q8WUF5 RelA-associated inhibitor chr19 Not Cancer Driver No 1 hippie, biogrid 117 657 90 90 0
PRRG4 PRRG4 Q9BZD6 Transmembrane gamma-carboxyglutamic acid protein 4 chr11 Not Cancer Driver No 1 hippie 17 53 8 8 0
PSMA7 PSMA7 O14818 Proteasome subunit alpha type-7 chr20 Not Cancer Driver No 1 hippie 24 23 1 1 0
PTPN18 PTPN18 Q99952 Tyrosine-protein phosphatase non-receptor type 18 chr2 Not Cancer Driver No 1 hippie 51 138 8 8 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 24 0 0 0 4
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RHOQ RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 Not Cancer Driver No 1 hippie 25 0 0 0 0
RIN1 RIN1 Q13671 Ras and Rab interactor 1 chr11 Not Cancer Driver No 3 hippie, biogrid 76 376 43 43 0
SF1_ENST00000377390 SF1 Q15637 Splicing factor 1 chr11 Not Cancer Driver No 1 hippie 110 627 106 106 0
SIVA1 SIVA1 O15304 Apoptosis regulatory protein Siva chr14 Not Cancer Driver No 1 hippie 20 20 6 6 0
SORBS2_ENST00000284776 SORBS2 O94875 Sorbin and SH3 domain-containing protein 2 chr4 Not Cancer Driver No 1 hippie 172 854 137 137 0
SORBS3 SORBS3 O60504 Vinexin chr8 Not Cancer Driver No 1 hippie, biogrid 62 577 56 56 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
TPD52L1_ENST00000534000 TPD52L1 Q16890 Tumor protein D53 chr6 Not Cancer Driver No 1 hippie 46 170 38 38 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIP10 TRIP10 Q15642 Cdc42-interacting protein 4 chr19 Not Cancer Driver No 1 hippie 72 460 61 61 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie, biogrid 84 316 57 57 1
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
ZMAT1_ENST00000540921 ZMAT1 Q5H9K5 Zinc finger matrin-type protein 1 chrX Not Cancer Driver No 1 hippie 131 388 80 80 0