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ABCD3 ,ABCD3 ,P28288
  • Uniprot Accession= P28288
  • Ensembl Transcript= ENST00000370214.8
  • Uniprot Name= ABCD3
  • Name= ATP-binding cassette sub-family D member 3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 48
  • Number of Interaction partner in biogrid: 88
  • Number of Interaction partner in hippie: 216
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX Not Cancer Driver No 2 intact, hippie, biogrid 106 75 5 5 138
ABCD2 ABCD2 Q9UBJ2 ATP-binding cassette sub-family D member 2 chr12 Not Cancer Driver No 1 hippie 150 29 4 4 0
ABCD3 ABCD3 P28288 ATP-binding cassette sub-family D member 3 chr1 Not Cancer Driver No 1 intact, hippie 75 21 2 2 0
ACBD5_ENST00000375888 ACBD5 Q5T8D3 Acyl-CoA-binding domain-containing protein 5 chr10 Not Cancer Driver No 1 hippie, biogrid 65 330 45 45 0
AGPS AGPS O00116 Alkyldihydroxyacetonephosphate synthase, peroxisomal chr2 Not Cancer Driver No 1 hippie, biogrid 68 151 10 10 6
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
ANKRD55 ANKRD55 Q3KP44 Ankyrin repeat domain-containing protein 55 chr5 Not Cancer Driver No 1 hippie 95 339 63 63 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 18 5 0 0 0
ARHGEF16 ARHGEF16 Q5VV41 Rho guanine nucleotide exchange factor 16 chr1 Not Cancer Driver No 1 hippie, biogrid 68 297 13 13 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 157 80 11 11 1
ATP2A3_ENST00000397041 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 Not Cancer Driver No 1 hippie, biogrid 130 147 16 16 0
ATP2B2 ATP2B2 Q01814 Plasma membrane calcium-transporting ATPase 2 chr3 Not Cancer Driver No 1 hippie, biogrid 248 360 82 82 0
ATP6V1C1_ENST00000518738 ATP6V1C1 P21283 V-type proton ATPase subunit C 1 chr8 Not Cancer Driver No 1 hippie, biogrid 54 17 3 3 0
AURKAIP1_ENST00000321751 AURKAIP1 Q9NWT8 Aurora kinase A-interacting protein chr1 Not Cancer Driver No 1 hippie 18 104 8 8 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 Not Cancer Driver No 1 hippie 14 163 14 14 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
BRF2 BRF2 Q9HAW0 Transcription factor IIIB 50 kDa subunit chr8 Not Cancer Driver No 1 hippie 40 138 13 13 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 80 45 4 4 0
C15orf48_ENST00000396650 NMES1 Q9C002 Normal mucosa of esophagus-specific gene 1 protein chr15 Not Cancer Driver No 1 intact 14 10 1 1 0
CBX4 CBX4 O00257 E3 SUMO-protein ligase CBX4 chr17 Not Cancer Driver No 1 hippie 72 477 63 63 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 29 54 9 9 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 Not Cancer Driver No 1 hippie 26 95 11 11 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie 50 34 2 2 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CLK2 CLK2 P49760 Dual specificity protein kinase CLK2 chr1 Not Cancer Driver No 1 hippie, biogrid 104 151 37 37 0
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 Not Cancer Driver No 1 intact, hippie 58 69 10 10 9
COL6A2 COL6A2 P12110 Collagen alpha-2(VI) chain chr21 Not Cancer Driver No 1 hippie 220 460 97 97 10
COQ9 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 43 111 13 13 0
COX14_ENST00000550654 COX14 Q96I36 Cytochrome c oxidase assembly protein COX14 chr12 Not Cancer Driver No 1 intact, hippie 4 7 0 0 1
COX15 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 48 0 0 0 2
COX6B1_ENST00000592141 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 1 hippie 15 23 6 6 2
CRELD1_ENST00000383811 CRELD1 Q96HD1 Protein disulfide isomerase CRELD1 chr3 Not Cancer Driver No 1 hippie, biogrid 45 44 7 7 4
CTDNEP1_ENST00000318988 CTDNEP1 O95476 CTD nuclear envelope phosphatase 1 chr17 Not Cancer Driver No 1 intact, hippie 20 0 0 0 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 64 102 2 2 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DEPDC1B DEPDC1B Q8WUY9 DEP domain-containing protein 1B chr5 Not Cancer Driver No 1 hippie, biogrid 76 52 6 6 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 Compendium Yes 1 hippie, biogrid 182 331 42 42 0
DOCK2 DOCK2 Q92608 Dedicator of cytokinesis protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 480 266 79 79 2
DOCK3 DOCK3 Q8IZD9 Dedicator of cytokinesis protein 3 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 365 458 69 69 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 135 447 73 73 0
DYRK1B_ENST00000323039 DYRK1B Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B chr19 Not Cancer Driver No 1 hippie 77 319 38 38 2
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EEF2 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 hippie, biogrid 111 78 14 14 1
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 Not Cancer Driver No 1 intact 147 211 38 38 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 58 176 15 15 0
FAF2 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 1 hippie 54 171 16 16 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FIS1 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 Not Cancer Driver No 1 hippie, biogrid 25 6 0 0 0
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 hippie, biogrid 71 160 25 25 0
GNAO1_ENST00000638705 GNAO1 P09471 Guanine nucleotide-binding protein G(o) subunit alpha chr16 Not Cancer Driver No 1 hippie 54 10 0 0 15
GOLT1B GOLT1B Q9Y3E0 Vesicle transport protein GOT1B chr12 Not Cancer Driver No 1 intact, hippie 26 0 0 0 0
GPR182 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 hippie, biogrid 49 33 4 4 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 Not Cancer Driver No 1 hippie, biogrid 44 219 32 32 2
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie 37 77 9 9 0
HIPK4 HIPK4 Q8NE63 Homeodomain-interacting protein kinase 4 chr19 Not Cancer Driver No 1 hippie 87 258 23 23 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 intact, hippie 107 16 4 4 18
HSD17B11 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 Not Cancer Driver No 1 hippie, biogrid 28 3 0 0 0
HSD3B7 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 Not Cancer Driver No 1 hippie, biogrid 43 27 5 5 2
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 20
INS INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 15 5 1 1 22
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KLF15 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 Not Cancer Driver No 1 hippie 66 273 48 48 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 3 intact, hippie, biogrid 788 7 2 2 27
KRT18_ENST00000388837 KRT18 P05783 Keratin, type I cytoskeletal 18 chr12 Not Cancer Driver No 1 hippie, biogrid 57 179 21 21 4
LACC1 LACC1 Q8IV20 Purine nucleoside phosphorylase LACC1 chr13 Not Cancer Driver No 1 intact, hippie 50 4 0 0 1
LMAN1 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie, biogrid 63 222 25 25 1
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 79 165 20 20 0
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 14 328 14 14 0
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 Not Cancer Driver No 1 hippie, biogrid 70 411 58 58 0
MDC1 MDC1 Q14676 Mediator of DNA damage checkpoint protein 1 chr6 Not Cancer Driver No 1 hippie 249 1829 223 223 0
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 287 749 159 159 3
MEST MEST Q5EB52 Mesoderm-specific transcript homolog protein chr7 Not Cancer Driver No 1 hippie, biogrid 34 0 0 0 0
METTL7A_ENST00000332160 METTL7A Q9H8H3 Putative methyltransferase-like protein 7A chr12 Not Cancer Driver No 1 hippie, biogrid 31 0 0 0 0
MEX3C MEX3C Q5U5Q3 RNA-binding E3 ubiquitin-protein ligase MEX3C chr18 Not Cancer Driver No 1 intact 54 475 32 32 0
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 540 3169 529 529 0
MLF2_ENST00000542154 MLF2 Q15773 Myeloid leukemia factor 2 chr12 Not Cancer Driver No 1 hippie, biogrid 37 187 32 32 0
MMS19 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 Not Cancer Driver No 1 hippie 73 11 0 0 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MPV17 MPV17 P39210 Protein Mpv17 chr2 Not Cancer Driver No 1 hippie, biogrid 21 0 0 0 16
MRPL41 MRPL41 Q8IXM3 39S ribosomal protein L41, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 18 23 1 1 0
MTCH1 MTCH1 Q9NZJ7 Mitochondrial carrier homolog 1 chr6 Not Cancer Driver No 1 hippie, biogrid 31 102 2 2 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie, biogrid 45 11 0 0 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYH14_ENST00000596571 MYH14 Q7Z406 Myosin-14 chr19 Not Cancer Driver No 1 intact, hippie 275 1215 169 169 5
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 123 117 42 42 0
NDUFA4 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 Not Cancer Driver No 1 hippie, biogrid 14 4 0 0 0
NDUFAF4 NDUFAF4 Q9P032 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 chr6 Not Cancer Driver No 1 hippie 14 46 4 4 2
NDUFB11_ENST00000377811 NDUFB11 Q9NX14 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 26 51 6 6 1
NDUFS4 NDUFS4 O43181 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 26 92 17 17 1
NDUFV1 NDUFV1 P49821 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 66 57 9 9 3
NEFM NEFM P07197 Neurofilament medium polypeptide chr8 Not Cancer Driver No 1 hippie, biogrid 182 767 147 147 0
NET1 NET1 Q7Z628 Neuroepithelial cell-transforming gene 1 protein chr10 Not Cancer Driver No 1 hippie, biogrid 60 294 37 37 0
NNT_ENST00000344920 NNT Q13423 NAD(P) transhydrogenase, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 129 47 6 6 11
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUDCD1 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 intact 75 38 4 4 0
NUP155 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 Not Cancer Driver No 1 hippie, biogrid 154 221 19 19 1
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OCIAD1 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 2 hippie, biogrid 37 169 25 25 0
OPA3_ENST00000263275 OPA3 Q9H6K4 Optic atrophy 3 protein chr19 Not Cancer Driver No 1 hippie 18 44 7 7 2
PBXIP1 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 100 605 86 86 0
PCM1 PCM1 Q15154 Pericentriolar material 1 protein chr8 Census Yes 1 intact, hippie 152 1665 134 134 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PELO PELO Q9BRX2 Protein pelota homolog chr5 Not Cancer Driver No 1 intact, hippie, biogrid 38 67 10 10 0
PEX14 PEX14 O75381 Peroxisomal membrane protein PEX14 chr1 Not Cancer Driver No 2 hippie, biogrid 38 266 28 28 0
PEX19 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 Not Cancer Driver No 4 intact, hippie 41 266 38 38 0
PEX3 PEX3 P56589 Peroxisomal biogenesis factor 3 chr6 Not Cancer Driver No 2 hippie, biogrid 31 24 0 0 2
PGRMC1 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX Not Cancer Driver No 1 hippie, biogrid 30 74 16 16 0
PHYH PHYH O14832 Phytanoyl-CoA dioxygenase, peroxisomal chr10 Not Cancer Driver No 1 hippie 54 40 4 4 14
PIM3 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 24 9 0 0 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLGRKT PLGRKT Q9HBL7 Plasminogen receptor (KT) chr9 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 Census Yes 1 hippie 201 189 33 33 2
PSMA1_ENST00000396394 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 Not Cancer Driver No 1 intact, hippie 48 51 9 9 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie 23 67 6 6 0
PTP4A3_ENST00000521578 PTP4A3 O75365 Protein tyrosine phosphatase type IVA 3 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 30 3 0 0 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 49 140 25 25 0
PTRH2_ENST00000470557 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 Not Cancer Driver No 1 hippie 14 19 2 2 1
PXMP2 PXMP2 Q9NR77 Peroxisomal membrane protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 15 0 0 0 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie 174 291 99 99 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 1 hippie, biogrid 31 43 4 4 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 22 58 4 4 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
RAB3B RAB3B P20337 Ras-related protein Rab-3B chr1 Not Cancer Driver No 1 hippie, biogrid 36 25 6 6 0
RAB4A RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie, biogrid 26 32 11 11 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 2 intact, hippie, biogrid 32 65 15 15 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 24 50 4 4 0
RAB5IF_ENST00000373852 RAB5IF Q9BUV8 Respirasome Complex Assembly Factor 1 chr20 Not Cancer Driver No 1 hippie 7 13 0 0 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 2 intact, hippie, biogrid 27 11 0 0 4
RAB9A RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 2 intact, hippie, biogrid 18 21 1 1 0
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 24 0 0 0 4
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 1 intact, hippie 89 169 38 38 22
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RETREG2 RETREG2 Q8NC44 Reticulophagy regulator 2 chr2 Not Cancer Driver No 1 intact, hippie 61 318 43 43 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 30 53 7 7 0
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 20 10 0 0 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 41 12 3 3 0
RHOT2 RHOT2 Q8IXI1 Mitochondrial Rho GTPase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 52 79 5 5 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie 119 232 34 34 3
RMDN3 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 45 196 17 17 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 19 54 4 4 0
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 167 220 28 28 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RTRAF RTRAF Q9Y224 RNA transcription, translation and transport factor protein chr14 Not Cancer Driver No 1 intact, hippie 24 35 1 1 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 37 214 37 37 0
SCARB2 SCARB2 Q14108 Lysosome membrane protein 2 chr4 Not Cancer Driver No 1 hippie 61 13 3 3 1
SCN3B_ENST00000299333 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 Not Cancer Driver No 1 hippie, biogrid 63 16 5 5 3
SEC61B SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 hippie, biogrid 11 60 7 7 0
SEC63 SEC63 Q9UGP8 Translocation protein SEC63 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 98 266 37 37 0
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 hippie, biogrid 31 29 1 1 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 33 164 12 12 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SLC25A46 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 Not Cancer Driver No 1 hippie, biogrid 37 96 2 2 4
SLC39A4 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 Not Cancer Driver No 2 hippie, biogrid 77 116 11 11 9
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 52 97 11 11 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 Not Cancer Driver No 1 intact, hippie 28 400 24 24 4
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 intact, hippie 96 599 71 71 0
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 intact, hippie 63 332 44 44 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 73 252 38 38 1
STARD8_ENST00000374597 STARD8 Q92502 StAR-related lipid transfer protein 8 chrX Not Cancer Driver No 1 hippie, biogrid 145 574 86 86 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STOM STOM P27105 Stomatin chr9 Not Cancer Driver No 2 intact, hippie 23 44 3 3 0
SUB1_ENST00000515355 SUB1 P53999 Activated RNA polymerase II transcriptional coactivator p15 chr5 Not Cancer Driver No 1 hippie 13 108 6 6 0
SURF1 SURF1 Q15526 Surfeit locus protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 17 82 6 6 11
SYNJ2BP SYNJ2BP P57105 Synaptojanin-2-binding protein chr14 Not Cancer Driver No 1 hippie, biogrid 27 12 4 4 0
TAP1 TAP1 Q03518-2 Isoform 2 of Antigen peptide transporter 1 chr6 Not Cancer Driver No 1 hippie, biogrid 67 83 6 6 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 68 169 23 23 0
TFDP1 TFDP1 Q14186 Transcription factor Dp-1 chr13 Not Cancer Driver No 1 hippie 82 245 47 47 0
TIMMDC1 TIMMDC1 Q9NPL8 Complex I assembly factor TIMMDC1, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 44 50 6 6 0
TMEM41B_ENST00000611268 TMEM41B Q5BJD5 Transmembrane protein 41B chr11 Not Cancer Driver No 1 hippie 19 47 3 3 0
TMEM63B TMEM63B Q5T3F8 CSC1-like protein 2 chr6 Not Cancer Driver No 1 intact, hippie 108 78 12 12 0
TMEM67 TMEM67 Q5HYA8 Meckelin chr8 Not Cancer Driver No 1 intact, hippie 120 11 0 0 37
TOMM20 TOMM20 Q15388 Mitochondrial import receptor subunit TOM20 homolog chr1 Not Cancer Driver No 1 hippie 8 25 1 1 0
TOMM22 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 intact, hippie 18 83 9 9 0
TOMM40_ENST00000405636 TOMM40 O96008 Mitochondrial import receptor subunit TOM40 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 17 98 1 1 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
TUFT1 TUFT1 Q9NNX1 Tuftelin chr1 Not Cancer Driver No 1 intact, hippie 45 295 34 34 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX Compendium Yes 1 hippie 35 67 13 13 2
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
UNK UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 79 511 46 46 0
USP11 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 1 hippie 140 210 28 28 0
USP32 USP32 Q8NFA0 Ubiquitin carboxyl-terminal hydrolase 32 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 182 401 43 43 0
USP50 USP50 Q70EL3 Inactive ubiquitin carboxyl-terminal hydrolase 50 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 33 2 0 0 0
VAPA_ENST00000400000 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 1 intact, hippie 24 184 14 14 0
VAV1 VAV1 P15498 Proto-oncogene vav chr19 Census, Compendium Yes 1 intact, hippie, biogrid 165 113 19 19 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
ZBTB2 ZBTB2 Q8N680 Zinc finger and BTB domain-containing protein 2 chr6 Not Cancer Driver No 1 hippie 75 216 30 30 0
ZFPL1 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie, biogrid 40 127 16 16 0
ZNF454 ZNF454 Q8N9F8 Zinc finger protein 454 chr5 Not Cancer Driver No 1 hippie, biogrid 122 150 37 37 0
ZNF746_ENST00000340622 ZNF746 Q6NUN9 Zinc finger protein 746 chr7 Not Cancer Driver No 1 hippie 93 436 56 56 0