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TM2D1_ENST00000294613 ,TM2D1 ,Q9BX74
  • Uniprot Accession= Q9BX74
  • Ensembl Transcript= ENST00000294613.9
  • Uniprot Name= TM2D1
  • Name= TM2 domain-containing protein 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 6
GO term GO name GO namespace GO def
GO:0005887 integral component of plasma membrane cellular_component The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. [GOC:dos, GOC:go_curators]
GO:0001540 amyloid-beta binding molecular_function Binding to an amyloid-beta peptide/protein. [GOC:hjd]
GO:0007186 G protein-coupled receptor signaling pathway biological_process A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane. [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor]
GO:0097190 apoptotic signaling pathway biological_process A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered. [GOC:mtg_apoptosis]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0004930 G protein-coupled receptor activity molecular_function Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. [GOC:bf, http://www.iuphar-db.org, Wikipedia:GPCR]