| GO term | GO name | GO namespace | GO def |
| GO:0005488 | binding | molecular_function | The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. [GOC:ceb, GOC:mah, ISBN:0198506732] |
| GO:0016020 | membrane | cellular_component | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
| GO:0036094 | small molecule binding | molecular_function | Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule. [GOC:curators, GOC:pde, GOC:pm] |
| GO:0006629 | lipid metabolic process | biological_process | The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. [GOC:ma] |
| GO:0050794 | regulation of cellular process | biological_process | Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:go_curators] |
| GO:0051171 | regulation of nitrogen compound metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. [GOC:ai, GOC:tb] |
| GO:0009891 | positive regulation of biosynthetic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. [GOC:go_curators] |
| GO:0044238 | primary metabolic process | biological_process | The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. [GOC:go_curators, http://www.metacyc.org] |
| GO:0016747 | acyltransferase activity, transferring groups other than amino-acyl groups | molecular_function | Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor). [GOC:jl] |
| GO:0051247 | positive regulation of protein metabolic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein. [GOC:ai] |
| GO:0008203 | cholesterol metabolic process | biological_process | The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues. [ISBN:0198506732] |
| GO:0042632 | cholesterol homeostasis | biological_process | Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell. [GOC:go_curators] |
| GO:0017076 | purine nucleotide binding | molecular_function | Binding to a purine nucleotide, a compound consisting of a purine nucleoside esterified with (ortho)phosphate. [GOC:ai] |
| GO:0071840 | cellular component organization or biogenesis | biological_process | A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. [GOC:mah] |
| GO:0031325 | positive regulation of cellular metabolic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. [GOC:mah] |
| GO:0009893 | positive regulation of metabolic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. [GOC:go_curators] |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | biological_process | Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. [GOC:dph, GOC:tb] |
| GO:0022607 | cellular component assembly | biological_process | The aggregation, arrangement and bonding together of a cellular component. [GOC:isa_complete] |
| GO:0048869 | cellular developmental process | biological_process | A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. [GOC:isa_complete] |
| GO:0008202 | steroid metabolic process | biological_process | The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. [ISBN:0198547684] |
| GO:0030258 | lipid modification | biological_process | The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid. [GOC:mah] |
| GO:0044255 | cellular lipid metabolic process | biological_process | The chemical reactions and pathways involving lipids, as carried out by individual cells. [GOC:jl] |
| GO:0015850 | organic hydroxy compound transport | biological_process | The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom. [GOC:ai] |
| GO:0043933 | protein-containing complex organization | biological_process | Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex. [GOC:mah] |
| GO:0051234 | establishment of localization | biological_process | Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. [GOC:ai, GOC:dos] |
| GO:0065007 | biological regulation | biological_process | Any process that modulates a measurable attribute of any biological process, quality or function. [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] |
| GO:0034381 | plasma lipoprotein particle clearance | biological_process | The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:ascb_2009, GOC:BHF, GOC:dph, GOC:mah, GOC:tb] |
| GO:0000166 | nucleotide binding | molecular_function | Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. [GOC:mah, ISBN:0198547684] |
| GO:0030301 | cholesterol transport | biological_process | The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah, ISBN:0198506732] |
| GO:0016021 | integral component of membrane | cellular_component | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. [GOC:dos, GOC:go_curators] |
| GO:0005783 | endoplasmic reticulum | cellular_component | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). [ISBN:0198506732] |
| GO:0031328 | positive regulation of cellular biosynthetic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. [GOC:mah] |
| GO:1901360 | organic cyclic compound metabolic process | biological_process | The chemical reactions and pathways involving organic cyclic compound. [GOC:TermGenie] |
| GO:0030154 | cell differentiation | biological_process | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. [ISBN:0198506732] |
| GO:2000112 | regulation of cellular macromolecule biosynthetic process | biological_process | Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process. [GOC:obol] |
| GO:0032501 | multicellular organismal process | biological_process | Any biological process, occurring at the level of a multicellular organism, pertinent to its function. [GOC:curators, GOC:dph, GOC:isa_complete, GOC:tb] |
| GO:1901363 | heterocyclic compound binding | molecular_function | Binding to heterocyclic compound. [GOC:TermGenie] |
| GO:0032502 | developmental process | biological_process | A biological process whose specific outcome is the progression of an integrated living unit |
| GO:0033218 | amide binding | molecular_function | Binding to an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. [GOC:mah] |
| GO:0048518 | positive regulation of biological process | biological_process | Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:jid] |
| GO:0016746 | acyltransferase activity | molecular_function | Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). [GOC:jl, ISBN:0198506732] |
| GO:0071702 | organic substance transport | biological_process | The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon. [GOC:mah] |
| GO:0019222 | regulation of metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. [GOC:go_curators] |
| GO:0051246 | regulation of protein metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. [GOC:ai] |
| GO:0006869 | lipid transport | biological_process | The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. [ISBN:0198506732] |
| GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
| GO:1901265 | nucleoside phosphate binding | molecular_function | Binding to nucleoside phosphate. [GOC:TermGenie] |
| GO:0060255 | regulation of macromolecule metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. [GOC:dph, GOC:tb] |
| GO:0015485 | cholesterol binding | molecular_function | Binding to cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. [GOC:jl, ISBN:0198506732] |
| GO:0019915 | lipid storage | biological_process | The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. [GOC:dph, GOC:mah, GOC:tb, PMID:11102830] |
| GO:0097159 | organic cyclic compound binding | molecular_function | Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure. [GOC:sjw, PMID:7583672] |
| GO:0097367 | carbohydrate derivative binding | molecular_function | Binding to a carbohydrate derivative. [GOC:pr] |
| GO:0065003 | protein-containing complex assembly | biological_process | The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. [GOC:jl] |
| GO:0051179 | localization | biological_process | Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. [GOC:ai, GOC:dos] |
| GO:0050789 | regulation of biological process | biological_process | Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:ai, GOC:go_curators] |
| GO:0016043 | cellular component organization | biological_process | A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. [GOC:ai, GOC:jl, GOC:mah] |
| GO:0051235 | maintenance of location | biological_process | Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere. [GOC:ai, GOC:dph, GOC:tb] |
| GO:0016740 | transferase activity | molecular_function | Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. [ISBN:0198506732] |
| GO:0005789 | endoplasmic reticulum membrane | cellular_component | The lipid bilayer surrounding the endoplasmic reticulum. [GOC:mah] |
| GO:0009889 | regulation of biosynthetic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. [GOC:go_curators] |
| GO:0009987 | cellular process | biological_process | Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:go_curators, GOC:isa_complete] |
| GO:0010556 | regulation of macromolecule biosynthetic process | biological_process | Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. [GOC:dph, GOC:tb] |
| GO:0008152 | metabolic process | biological_process | The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. [GOC:go_curators, ISBN:0198547684] |
| GO:0048522 | positive regulation of cellular process | biological_process | Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [GOC:jid] |
| GO:0031323 | regulation of cellular metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. [GOC:mah] |
| GO:0010604 | positive regulation of macromolecule metabolic process | biological_process | Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. [GOC:dph, GOC:tb] |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. [GOC:ai, GOC:tb] |
| GO:0003824 | catalytic activity | molecular_function | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [GOC:vw, ISBN:0198506732] |
| GO:0044237 | cellular metabolic process | biological_process | The chemical reactions and pathways by which individual cells transform chemical substances. [GOC:go_curators] |
| GO:0006810 | transport | biological_process | The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein. [GOC:dos, GOC:dph, GOC:jl, GOC:mah] |
| GO:0015918 | sterol transport | biological_process | The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. [GOC:ai] |
| GO:0031326 | regulation of cellular biosynthetic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. [GOC:mah] |
| GO:0080090 | regulation of primary metabolic process | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. [PMID:19211694] |
| GO:0071704 | organic substance metabolic process | biological_process | The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. [GOC:mah] |
| GO:0008374 | O-acyltransferase activity | molecular_function | Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule. [GOC:ai] |