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RCOR3_ENST00000367005 ,RCOR3 ,Q9P2K3
  • Uniprot Accession= Q9P2K3
  • Ensembl Transcript= ENST00000367005.8
  • Uniprot Name= RCOR3
  • Name= REST corepressor 3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 9
GO term GO name GO namespace GO def
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0003714 transcription corepressor activity molecular_function A transcription coregulator activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. [GOC:txnOH-2018, PMID:10213677, PMID:16858867]
GO:0005667 transcription regulator complex cellular_component A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription. [GOC:jl]
GO:0000118 histone deacetylase complex cellular_component A protein complex that possesses histone deacetylase activity. [GOC:mah]
GO:0016575 histone deacetylation biological_process The modification of histones by removal of acetyl groups. [GOC:ai]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0006357 regulation of transcription by RNA polymerase II biological_process Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. [GOC:go_curators, GOC:txnOH]
GO:0045892 negative regulation of transcription, DNA-templated biological_process Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. [GOC:go_curators, GOC:txnOH]