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RBBP5 ,RBBP5 ,Q15291
  • Uniprot Accession= Q15291
  • Ensembl Transcript= ENST00000264515.10
  • Uniprot Name= RBBP5
  • Name= Retinoblastoma-binding protein 5
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 30
GO term
GO name
GO namespace
GO def
GO:0051568 histone H3-K4 methylation biological_process The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone. [GOC:ai, GOC:pr]
GO:0032991 protein-containing complex cellular_component A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. [GOC:dos, GOC:mah]
GO:0008168 methyltransferase activity molecular_function Catalysis of the transfer of a methyl group to an acceptor molecule. [ISBN:0198506732]
GO:0035097 histone methyltransferase complex cellular_component A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins. [GOC:bf]
GO:0016740 transferase activity molecular_function Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. [ISBN:0198506732]
GO:1990234 transferase complex cellular_component A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). [GOC:bhm, PMID:16540464]
GO:0050896 response to stimulus biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. [GOC:ai, GOC:bf]
GO:0016278 lysine N-methyltransferase activity molecular_function Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue. [GOC:mah]
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity molecular_function Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate. [GOC:mah]
GO:0003824 catalytic activity molecular_function Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [GOC:vw, ISBN:0198506732]
GO:0042054 histone methyltransferase activity molecular_function Catalysis of the reaction
GO:0000976 transcription cis-regulatory region binding molecular_function Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. [GOC:txnOH]
GO:0006325 chromatin organization biological_process Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. [GOC:mah, GOC:vw, PMID:20404130]
GO:0010033 response to organic substance biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. [GOC:sm, PMID:23356676]
GO:0005730 nucleolus cellular_component A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. [ISBN:0198506732]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0016279 protein-lysine N-methyltransferase activity molecular_function Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate. [PMID:12054878]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0042221 response to chemical biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. [GOC:jl]
GO:1902494 catalytic complex cellular_component A protein complex which is capable of catalytic activity. [GOC:bhm, GOC:TermGenie, PMID:8077207]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0006974 cellular response to DNA damage stimulus biological_process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. [GOC:go_curators]
GO:0008276 protein methyltransferase activity molecular_function Catalysis of the transfer of a methyl group (CH3-) to a protein. [GOC:jl, ISBN:0198506732]
GO:0140096 catalytic activity, acting on a protein molecular_function Catalytic activity that acts to modify a protein. [GOC:molecular_function_refactoring, GOC:pdt]
GO:0008170 N-methyltransferase activity molecular_function Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule. [GOC:ai]
GO:0016741 transferase activity, transferring one-carbon groups molecular_function Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor). [GOC:jl, ISBN:0198506732]
GO:0018024 histone-lysine N-methyltransferase activity molecular_function Catalysis of the reaction
GO:0009719 response to endogenous stimulus biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. [GOC:sm]
GO:0009725 response to hormone biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. [GOC:jl]
GO:0035064 methylated histone binding molecular_function Binding to a histone in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. [GOC:bf, PMID:14585615]