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PLCH2 ,PLCH2 ,O75038
  • Uniprot Accession= O75038
  • Ensembl Transcript= ENST00000378486.7
  • Uniprot Name= PLCH2
  • Name= 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 14
GO term GO name GO namespace GO def
GO:0004629 phospholipase C activity molecular_function Catalysis of the reaction
GO:0048015 phosphatidylinositol-mediated signaling biological_process A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives. [GOC:bf, GOC:ceb, ISBN:0198506732]
GO:0016788 hydrolase activity, acting on ester bonds molecular_function Catalysis of the hydrolysis of any ester bond. [GOC:jl]
GO:0046488 phosphatidylinositol metabolic process biological_process The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. [ISBN:0198506732]
GO:0016787 hydrolase activity molecular_function Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. [ISBN:0198506732]
GO:0004620 phospholipase activity molecular_function Catalysis of the hydrolysis of a glycerophospholipid. [ISBN:0198506732]
GO:0042578 phosphoric ester hydrolase activity molecular_function Catalysis of the reaction
GO:0016042 lipid catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. [GOC:go_curators]
GO:0003824 catalytic activity molecular_function Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [GOC:vw, ISBN:0198506732]
GO:0016298 lipase activity molecular_function Catalysis of the hydrolysis of a lipid or phospholipid. [GOC:mah]
GO:0005509 calcium ion binding molecular_function Binding to a calcium ion (Ca2+). [GOC:ai]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0008081 phosphoric diester hydrolase activity molecular_function Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group. [EC:3.1.4.-, GOC:curators]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]